Dual-Channel Phase-Tunable Down Converter With LO Frequency Doubling by Yunxin Wang, Hongbiao Zhang, Dayong Wang, Tao Zhou, Feng Yang, Xin Zhong, Zhiyu Chen, Dengcai Yang, Lu Rong

“…A dual-channel phase-tunable down converter with local oscillator (LO) frequency doubling is proposed by using a commercial dual-polarization dual-drive Mach-Zehnder modulator (DP-DMZM) and a specially designed dual-channel phase modulator (DP-PM). …”
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Decoding the impact of MMP1+ malignant subsets on tumor-immune interactions: insights from single-cell and spatial transcriptomics by Da-Ming Xu, Ling-Xiao Chen, Ting Xue, Xiao-Yu Zhuang, Li-Chao Wei, Hui Han, Miao Mo

“…MMP1 expression correlated with enhanced macrophage infiltration and impaired CD8+ T-cell function, contributing to an immunosuppressive tumor microenvironment. …”
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HENCE: Hardware End-to-End Neural Conditional Entropy Encoder for Lossless 3D Medical Image Compression by Jietao Chen, Qianhao Chen, Huan Zhang, Weijie Chen, Wei Luo, Feng Yu

“…To obtain the cumulative distribution function of the discrete logistic distribution, we further introduce a high-precision Sigmoid approximation algorithm, using the Newton-Raphson method. …”
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Multiple delivery strategies of nanocarriers for myocardial ischemia-reperfusion injury: current strategies and future prospective by Shengnan Li, Fengmei Li, Yan Wang, Wenqun Li, Junyong Wu, Xiongbin Hu, Tiantian Tang, Xinyi Liu

“…The pathogenesis of MI/RI involves several mechanisms, including overproduction of reactive oxygen species, abnormal mitochondrial function, calcium overload, and other factors that induce cell death and inflammatory responses. …”
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Is colloidal oat an effective emollient ingredient for the prevention and treatment of atopic dermatitis in infants? by Joseph F. Fowler, Lin Ma, James Bergman, Paul Horowitz, Tina Lavender, Lawrence F. Eichenfield, Zoe Draelos, Simon G. Danby, Michael J. Cork

“…Studies assessing skin barrier function, immune modulation, AD prevention, food allergy risk, and healthcare utilization were included.Results Colloidal oat emollients improved skin hydration, reduced transepidermal water loss (TEWL), and supported barrier repair, leading to fewer AD flares and reduced reliance on steroid treatments. …”
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Attention-Based Lightweight YOLOv8 Underwater Target Recognition Algorithm by Shun Cheng, Zhiqian Wang, Shaojin Liu, Yan Han, Pengtao Sun, Jianrong Li

“…Firstly, the SPDConv module is utilized in the backbone network to replace the standard convolutional module for feature extraction. …”
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Effect of a Scale‐Aware Convective Parameterization Scheme on the Simulation of Convective Cells‐Related Heavy Rainfall in South Korea by Haerin Park, Gayoung Kim, Dong‐Hyun Cha, Eun‐Chul Chang, Joowan Kim, Sang‐Hun Park, Dong‐Kyou Lee

“…The MSKF scheme uses a scale‐aware parameter that modulates the convective available potential energy (CAPE) timescale and entrainment process in the KF scheme as a function of the horizontal grid spacing. …”
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Mechanical feedback mechanisms in a multiscale sliding filament model of lymphatic muscle pumping by Peter Y. Xie, Christopher J. Morris, Christopher D. Bertram, Michael J. Davis, Samira Jamalian, Mohammad Jafarnejad, David C. Zawieja, James E. Moore, Jr

“…Lymph transport is important not only for fluid homeostasis, but also for immune function, as lymph is a carrier for immune cells. Lymphatic muscle cells exhibit both cardiac-like phasic contractions to generate flow and smooth-muscle-like tonic contractions to regulate flow. …”
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The Anticancer Effect of Genistein Through Enhancing PERK Signaling and Suppressing the IRE1α-XBP1 Axis in Canine Mammary Gland Tumor Cells by Ye-Ji Jang, Min-Jae Yoo, Hyuk Jang, Jun Song, Sang-Youel Park, Jawun Choi, Jae-Won Seol

“…On regulation of the UPR system, genistein treatment showed a dual-function by enhancing the protein kinase R-like endoplasmic reticulum kinase (PERK) signaling while suppressing the inositol-requiring enzyme 1 alpha (IRE1α)–X-box-binding protein 1 (XBP1) axis. …”
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Channel Amplitude and Phase Error Estimation of Fully Polarimetric Airborne SAR with 0.1 m Resolution by Jianmin Hu, Yanfei Wang, Jinting Xie, Guangyou Fang, Huanjun Chen, Yan Shen, Zhenyu Yang, Xinwen Zhang

“…Secondly, the paired-echo broadening function is obtained by selecting high-quality sample points after single-band imaging and the nonlinear phase error within the subbands is estimated via Sinusoidal Frequency Modulation Fourier Transform (SMFT). …”
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Increased CO₂ Concentration Mitigates the Impact of Nitrite on Zebrafish (<i>Danio rerio</i>) Liver and Gills by Xinyu Wang, Yao Tang, Hui Yang, Ya He, Kang Ou-Yang, Liangmou Wang, Qian Zhang, Dapeng Li, Li Li

“…In conclusion, our study suggests that in the presence of 2 mg/L nitrite, increased CO₂ (2.5–10 mg/L) may modulate ion transporter genes to reduce the chloride-dependent nitrite uptake and maintain pH homeostasis, concurrently alleviating oxidative stress, restoring mitochondrial respiratory function, and improving lipid metabolism in a dose-dependent manner. …”
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BLF1 Affects ATP Hydrolysis Catalyzed by Native and Mutated eIF4A1 and eIF4A2 Proteins by Min An, Xin Cheng, Yu Zhang, Jiang Gu, Xuhu Mao

“…Our findings provide molecular insights into the functional difference between eIF4A isoforms and suggest that BLF1 might be of promising value for anticancer therapies.…”
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Exploring the role of neutrophils in inflammatory pain hypersensitivity via single-cell transcriptome profiling by Kai Ding, Xing Liu, Bin Zeng, Songyu Liu, Lu Zhang, Bo Li, Jinyi Zhou, Xiaosan Su, Jun Wang

“…Using comprehensive bioinformatics techniques, we identified distinct cell subpopulations and characterized their gene expression profiles and functional attributes. Based on these analyses, NAMO was selected to intervene in neutrophil differentiation and maturation. …”
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Genome-Wide Identification of the GRAS Transcription Factor Family in Sweet Orange and the Regulation of Salt Stress-Enhanced Plant Salt Tolerance in Sweet Orange by <i>CsGRAS15</i... by Hailin Ren, Rong Xu, Jie Wang, Qian Zhang, Lili Nie, Li Zhang, Xianyan Zhou, Xiaozhen Liu, Hanyao Zhang

“…These genes reside on nine chromosomes, with segmental duplication being the primary evolutionary driver (eight duplicated pairs). Functional enrichment implicated hormone signaling pathways in regulating growth under stress. …”
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Unveiling the pivotal role of Ni doping in ilmenite as oxygen carrier to realize simultaneous enhanced oxygen release and inhibited phase segregation in chemical looping process by Haochen Sun, Susanna T. Maanoja, Lujiang Xu, Huan Liu, Daofeng Mei, Wen-Da Oh, Chao He

“…The superior performance of Ni doping could be attributed to the incorporation of Ni2+ element in Fe-O-Ti structure rather than Ni0, which was validated by pre-activation and cyclic experiments, and density functional theory calculations. Modulated electronic structure by Ni2+ in Fe-O-Ti lattice was responsible for significantly promoted oxygen release capacity and enhanced Fe/Ti interactions, thereby activating the reactivity of ilmenite with CH4 and suppressing Ti/Fe phase segregation. …”
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Compound probiotics alleviate hyperuricemia-induced renal injury via restoring gut microbiota and metabolism by Ping Liu, Ping Hu, Meiping Jin, Weiqian Sun, Jiajun Wu, Yuyan Tang, Danye Shi, Ting Xie, Yijing Tong, Lusheng Huang, Dongliang Zhang, Hui Zheng, Xudong Xu, Haidong He

“…Renal pathological and functional changes were assessed through H&E staining and plasma biochemical analysis. …”
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EMG-based body–machine interface for targeted trunk muscle activation by Carolina Correia, Andrea Bandini, Silvestro Micera, Sara Moccia

“…Deficits in trunk control, commonly observed in individuals with neurological conditions, can significantly impair balance, posture, and functional movements. Body–machine interfaces (BoMIs) are promising tools for trunk rehabilitation, as they can provide real-time feedback on user movements and muscle activity, allowing for continuous monitoring and guidance during motor control training. …”
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Single-cell and machine learning integration reveals ferroptosis-driven immune landscapes for melanoma stratification by Lei Wang, Lei Wang, Xueying Jin, Yuchen Wu, Runing Qiu, Jianfang Wang

“…BackgroundFerroptosis, a regulated form of cell death, has emerged as a critical modulator of melanoma's tumor progression and immune evasion. …”
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Lipid-Lowering Potential of Almond Hulls (Quercetin, Baicalein, and Kaempferol): Insights from Network Pharmacology and Molecular Dynamics by Qiming Miao, Lu Sun, Jiayuan Wu, Xinyue Zhu, Juer Liu, Roger Ruan, Guangwei Huang, Shengquan Mi, Yanling Cheng

“…These findings support its potential in functional foods and pharmaceuticals, though further in vivo validation and mechanistic investigations are required.…”
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Antimicrobial evaluation, molecular docking, DFT analysis, and ADME studies of 3-Hydroxypyridin-4-one analogues by Hossein Sadeghpour, Sara Sadeghian, Fateme Zare, Mehdi Jamali, Narjes Moghtaderi Estahbanati, Kamiar Zomorodian, Zahra Zareshahrabadi, Razieh Sabet

“…Molecular docking studies supported these findings by demonstrating strong binding affinities of potent compounds to bacterial Gyrase B and fungal sterol 14-alpha demethylase (CYP51). Density Functional Theory (DFT) calculations further elucidated the electronic properties correlating with reactivity and stability. …”
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