Effect of Droplet Contamination on Camera Lens Surfaces: Degradation of Image Quality and Object Detection Performance by Hyunwoo Kim, Yoseph Yang, Youngkwang Kim, Dong-Won Jang, Dongil Choi, Kang Park, Sangkug Chung, Daegeun Kim

“…Image quality degradation was analyzed using the modulation transfer function (MTF), with droplet volume and number as variables. …”
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Enhancing magnetostriction in FeAl alloys via crystal growth orientation tuning by a trace amount of Pt doping by Zhiyong Dai, Ruisheng Zhang, Chao Zhou, Yuanliang Chen, Sen Kong, Yin Zhang, Fanghua Tian, Wenliang Zuo, Yoshitaka Matsushita, Sen Yang, Kaiyun Chen, Xiaoping Song

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Identification of the metabolic protein ATP5MF as a potential therapeutic target of TNBC by Kaiyan Chen, Yingchun Wu, Linfeng Xu, Changyong Wang, Jinqiu Xue

“…Employing the high dimensional weighted gene coexpression network analysis (hdWGCNA) method, we analyzed the tumor epithelial cells from non-BRCA1/2 mutation TNBC to identify the functional module genes. PPI analysis and survival analysis were further emplyed to identify the key gene. siRNA-NC and siRNA-ATP5MF were transfected into two MDA-MB-231 and BT-549 TNBC cell lines. …”
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The mechanism of Weiqi decoction treating gastric cancer: a work based on network pharmacology and experimental verification by Xu Huang, Zhihong Pan, Lei Shen, Huan Chen, Chang Chen, Tingting Lv, Yuzhou Mei

“…GO enrichment analysis indicated involvement in 726 biological processes, 91 cellular components, and 177 molecular functions, while KEGG pathway analysis suggested modulation of the AGE-RAGE, PI3K-Akt, and HIF-1 signaling pathways. …”
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Weighted Gene Coexpression Network Analysis Identifies Neutrophil-Related Molecular Subtypes and Their Clinical Significance in Gastric Cancer by Chen C, Shao Y, Ye C, Yu X, Hu M, Yan J, Ye G

“…High-dimensional weighted gene coexpression network analysis (hdWGCNA) and multiple bioinformatics methods were utilized to classify the molecular subtypes of GC and further investigate the differences among the subtypes. Based on the module genes and differentially expressed genes (DEGs), random survival forest analysis was applied to identify the key prognostic genes for GC, and the roles and functional mechanisms of the key genes in GC were explored by clinical samples and cellular experiments.Results: Two distinct GC molecular subtypes (C1 and C2) associated with neutrophils were identified, with C1 associated with better prognosis. …”
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Structure, evolution, and roles of MYB transcription factors proteins in secondary metabolite biosynthetic pathways and abiotic stresses responses in plants: a comprehensive review by Ziming Ma, Ziming Ma, Lanjuan Hu, Yu Zhong

“…In this review, we examine the structural features, classification, and functional mechanisms of MYB transcription factors. …”
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Differential regulation of innate immune cytokine production through pharmacological activation of Nuclear Factor-Erythroid-2-Related Factor 2 (NRF2) in burn patient immune cells a... by Timothy K Eitas, Wesley H Stepp, Lucas Sjeklocha, Clayton V Long, Caitlin Riley, James Callahan, Yolanda Sanchez, Peter Gough, Laquanda Knowlin, David van Duin, Shiara Ortiz-Pujols, Samuel W Jones, Robert Maile, Zhi Hong, Scott Berger, Bruce A Cairns

“…Our work also demonstrates that the NRF2 pathway is retained and can be modulated to regulate important immunomodulatory functions in burn patient immune cells.…”
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TRIM26 as a dual regulator of ferroptosis and chemoresistance in gastric cancer through HSF1 ubiquitination and exosomal miR-24-3p signaling by Nouf S. Al-Abbas

“…TRIM26, an E3 ubiquitin ligase with emerging tumor-suppressive functions, has been implicated in various malignancies; however, its precise role in GC has not been fully elucidated. …”
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Advances in research on biomaterials and stem cell/exosome-based strategies in the treatment of traumatic brain injury by Wenya Chi, Yingying He, Shuisheng Chen, Lingyi Guo, Yan Yuan, Rongjie Li, Ruiyao Liu, Dairan Zhou, Jianzhong Du, Tao Xu, Yuan Yu

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The dimeric conformation of PRRSV nsp1α is important for its ability to regulate viral RNA synthesis by Qingyu Li, Jingbo Hu, Xue Jiao, Jing Shi, Chenxi Li, Yanhua Li

“…In this study, we aimed to elucidate the functional significance of nsp1α dimerization. Using the alanine scanning strategy, we identified valine132 and proline134 as critical residues for nsp1α dimerization. …”
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Genome-scale metabolic modelling of human gut microbes to inform rational community design by Juan Pablo Molina Ortiz, Dale David McClure, Andrew Holmes, Scott Alan Rice, Mark Norman Read, Erin Rose Shanahan

“…While DRC supplementation offers a means to modulate the microbiome therapeutically, its effectiveness is often limited by the microbial community’s complexity and individual variability in microbiome functionality. …”
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Exploration of biomarkers associated with histone lactylation modification in spinal cord injury by Yisong Sun, Jie Gao, Juehua Jing

“…Inter-cluster comparisons were conducted to examine Hallmark pathways, HLA genes, and immune functions. Weighted gene co-expression network analysis (WGCNA) was applied to identify cluster-related module genes, which were further used for protein-protein interaction (PPI) network construction to pinpoint key proteins. …”
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Enhancing the antibacterial ability of Ligilactobacillus salivarius through ARTP mutagenesis breeding: an effective strategy to improve its probiotic properties by Hetian Zhou, Hetian Zhou, Hetian Zhou, Yunping Du, Guolian Yu, Wei Liu, Juanjuan Zeng, Bin Wang, Bin Wang, Maojin Chen, Yujue Wang, Wenbo Zhang, Xiaona Wei, Xiaona Wei

“…IntroductionLigilactobacillus salivarius (L. salivarius), a well-characterized probiotic species with established safety and functional efficacy, has been widely applied in poultry production for decades. …”
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Disruption of the biorhythm in gastric epithelial cell triggers inflammation in Helicobacter pylori-associated gastritis by aberrantly regulating NFIL3 via CagA activated ERK-SP1 p... by Yongsheng Teng, Yipin Lv, Wanyan Chen, Fangyuan Mao, Liusheng Peng, He Huang, Haiyan Li, Liwei Shi, Quanming Zou, Yuan Zhuang, Wenqing Tian, Hong Guo

“…We aimed to investigate the functional roles and regulatory mechanisms of key biorhythm molecules in H. pylori associated gastritis. …”
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Global microRNA level regulation of EGFR‐driven cell‐cycle protein network in breast cancer by Stefan Uhlmann, Heiko Mannsperger, Jitao David Zhang, Emöke‐Ágnes Horvat, Christian Schmidt, Moritz Küblbeck, Frauke Henjes, Aoife Ward, Ulrich Tschulena, Katharina Zweig, Ulrike Korf, Stefan Wiemann, Özgür Sahin

“…Furthermore, the novel network‐analysis methodology we developed implied the existence of consistent intrinsic regulatory patterns where miRNAs simultaneously co‐regulate several proteins acting in the same functional module. Finally, our approach led us to identify and validate three miRNAs (miR‐124, miR‐147 and miR‐193a‐3p) as novel tumor suppressors that co‐target EGFR‐driven cell‐cycle network proteins and inhibit cell‐cycle progression and proliferation in breast cancer.…”
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Identification of pyroptosis related genes and subtypes in atherosclerosis using multiomic and single cell analysis by Kaisheng Jiang, Yang He, Bingjie Hu, Li Quan, Longyun Peng, Juntao Tian, Nan Zhou, Erwen Huang, Qianhao Zhao

“…A multi-omics framework integrating transcriptomics, single-cell RNA sequencing, and machine learning to identify and prioritize pyroptosis-related genes (PRGs) in AS. Functional enrichment, immune infiltration profiling, and protein–protein interaction network analyses were conducted. …”
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Development of conformation-selective antibodies targeting human SLC15A4 by Yalan Zhu, Xuyuan Zhang, Qixiang Zhang, Panpan Sun, Kexin Liu, Xiaohua Nie, Junxiao Ma, Liwei Zhang, Yina Gao, Yong Wang, Songqing Liu, Ang Gao, Liguo Zhang, Pu Gao

“…Abstract SLC15A4, an endolysosomal solute carrier family transporter, plays a critical role in TLR7/8/9-induced immune responses through assembling a complex with the downstream adaptor TASL in a conformation-dependent manner. Despite its close functional association and promising therapeutic potential in infections, tumors, and autoimmune diseases, the development of conformation-specific antibodies for human SLC15A4 (hSLC15A4) remains challenging. …”
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Dynamic Mechanical Load as a Trigger for Growth and Proliferation in Porcine Epithelial Cells by Stefan Kahlert, Constanze Nossol, Marcus Krüger, Sascha Kopp, Daniela Grimm, Simon L. Wuest, Hermann-Josef Rothkötter

“…The morphological and functional response of non-cancer-derived porcine epithelial cell lines IPEC-1 and IPEC-J2 was analyzed. …”
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Evidence from pupillometry, fMRI, and RNN modelling shows that gain neuromodulation mediates task-relevant perceptual switches by Gabriel Wainstein, Christopher J Whyte, Kaylena A Ehgoetz Martens, Eli J Müller, Vicente Medel, Britt Anderson, Elisabeth Stöttinger, James Danckert, Brandon R Munn, James M Shine

“…To test this hypothesis at a large-scale, we analysed an ambiguous figures task using pupillometry and functional magnetic resonance imaging (fMRI). Behaviourally, qualitative shifts in the perceptual interpretation of an ambiguous image were associated with peaks in pupil diameter, an indirect readout of phasic bursts in neuromodulatory tone. …”
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Observation of nanoparticle coalescence during core-shell metallic nanowire growth in colloids via nanoscale imaging by Dahai Yang, Xingyu Zhang, Ruijie Yang, Bolin Zou, Rui Huang, Colin Ophus, Chengyu Song, Sheng Cheng, Juyeong Kim, Hui Xiong, Xianqi Wu, Mufan Li, Yong Wang, Hongfa Xiang, Zihao Ou, Xiaohui Song

“…Abstract The surface morphology and shape of crystalline nanowires significantly influence their functional properties, including phonon transport, electrocatalytic performance, to name but a few. …”
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