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10181
Effects of axylitol-casein complex on insulin resistance and gut microbiota composition in high-fat-diet + streptozotocin-induced type 2 diabetes mellitus mice
Published 2024-09-01“…XC decreased body weight and improved glucose tolerance, insulin sensitivity, pancreas impairment, blood lipid levels, and liver function in T2DM mice compared to XY- and CN-treated mice. …”
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10182
Reprogramming CAR-T cells: Targeting SLC transporters for tumor microenvironment adaptation
Published 2025-10-01“…This review explores the critical role of SLC transporters in CAR-T cell functionality and discusses strategies to optimize their expression and activity within the challenging TME.…”
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10183
Role of Dietary Long-Chain Polyunsaturated Fatty Acids in Infant Allergies and Respiratory Diseases
Published 2012-01-01“…PUFAs act via several mechanisms to modulate immune function. Omega-3 PUFAs may alter the T helper (Th) cell balance by inhibiting cytokine production which in turn inhibits immunoglobulin E synthesis and Th type 2 cell differentiation. …”
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10184
A comprehensive review of molecular hydrogen as a novel nutrition therapy in relieving oxidative stress and diseases: Mechanisms and perspectives
Published 2025-03-01“…H2 demonstrates numerous biologically therapeutic properties, including anti-inflammatory, antioxidant, anti-cancer, anti-stress, anti-apoptotic, anti-allergic effects, signaling molecule functions, regulation of redox balance, modulation of antioxidant enzyme gene expression, improvement of blood vessel function, down-regulation of pro-inflammatory cytokines, stimulation of energy metabolism, and protection of the nervous system. …”
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10185
Active Dielectric Metasurfaces for Switchable Terahertz Beam Steering and Focusing
Published 2021-01-01“…Conventional metasurfaces often manipulate light propagation in a passive way, which cannot satisfy the dynamic operation requirements of many practical applications. Integrating functional materials or components into the structure design is one effective method, which, however, often introduces additional loss to the resonances, thus greatly affecting the efficiency of modulation. …”
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10186
OncoImmune machine-learning model predicts immune response and prognosis in leiomyosarcoma
Published 2025-06-01“…Mechanistically, we found that ATRX mutation may regulate coiled-coil domain-containing protein 69 (CCDC69) expression, leading to functional alterations in mast cells and immune unresponsiveness through the modulation of various immune-related signaling pathways. …”
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10187
In Vitro Prebiotic Potential of <i>Opuntia humifusa</i> Leaf Extract and Its Active Constituent
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10188
MLGFENet: Multiscale Local–Global Feature Enhancement Network for High-Resolution Remote Sensing Image Change Detection
Published 2025-01-01“…Additionally, a composite loss function is introduced, which takes into account both pixel-based segmentation errors and edge-based segmentation errors, enabling accurate localization of changed regions. …”
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10189
The lateral habenula contributes to regulation of body temperature
Published 2025-07-01“…Summary: The lateral habenula (LHb) is implicated in the regulation of numerous physiological functions, particularly those associated with thermoregulation. …”
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10190
Involvement of the Methyltransferase CcLaeA in Regulating Laccase Production in <i>Curvularia clavata</i> J1
Published 2025-03-01“…This finding indicates that CcLaeA functions as a transcriptional repressor of laccase biosynthesis. …”
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10191
Identification of clinical diagnostic and immune cell infiltration characteristics of acute myocardial infarction with machine learning approach
Published 2025-07-01“…Dysregulated expression of genes was screened and functionally analyzed. Weighted Gene Co-expression Network Analysis (WGCNA) was used to identify significant module genes associated with AMI. …”
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10192
Orbital inversion and emergent lattice dynamics in infinite layer CaCoO 2
Published 2025-06-01“…Further, our RIXS data reveal a strong low energy mode, with anomalous intensity modulations as a function of momentum transfer close to a quasi-static response. …”
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10193
Minimizing the Number of Spans for Terrestrial Fiber-Optic Systems Using Quasi-Single-Mode Transmission
Published 2018-01-01“…Together with amplified spontaneous emission noise, an optical signal-to-noise ratio (OSNR) for a fixed transmission distance as a function of the effective area of the FMF and span length can be obtained. …”
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10194
Resolving mechanisms of immune‐mediated disease in primary CD4 T cells
Published 2020-04-01“…To determine whether causal variants could be identified from their functional effects, we adapted a massively parallel reporter assay for use in primary CD4 T cells, the cell type whose regulatory DNA is most enriched for immune‐mediated disease SNPs. …”
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10195
On the regioselective molecular sieves-promoted oxidative three-component synthesis of fused-benzimidazoles from $\beta $-ketoesters
Published 2022-02-01“…Molecular sieves act both as heterogeneous catalyst and dehydrating agent and their role has been modeled in the theoretical approach. The modulation of the reactivity of the aromatic diamine partner as a function of the nature of the substituents of the aromatic ring and its influence on the regioselectivity of the reaction could be rationalized.…”
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10196
CircRNA-based AntimiR therapy: A novel approach to hypertension treatment
Published 2025-08-01“…The increasing recognition of the types and functions of non-coding RNAs has opened new avenues for their use as novel therapeutic strategies in the treatment of chronic diseases such as hypertension. …”
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10197
The PD-1/PD-L1 pathway and Epstein–Barr virus
Published 2025-06-01“…While the PD-1/PD-L1 pathway’s role in chronic viral infections is well-established, its specific functions in EBV infection remain poorly understood. …”
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10198
Gut Microbial Composition Is Associated with Symptom Self-Report in Trauma-Exposed Iraq and Afghanistan Veterans
Published 2025-01-01“…The gut microbiome has been implicated in modulation of critical processes beyond digestion, including immune system functioning and stress responsivity, and may be an important factor in understanding physical and mental health outcomes following deployment and trauma exposure. …”
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10199
Metabolomics-Based Pharmacodynamic Analysis of Zhuang Yao Shuang Lu Tong Nao Granules in a Rat Model of Ischemic Cerebral Infarction
Published 2022-01-01“…The neurological deficit scores were significantly higher in the MCAO_R group than in the NC group, indicating that the mice had significantly impaired motor functions. The YHT group had significantly lower scores than the MCAO_R group, suggesting that YHT significantly improved motor function in rats. …”
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10200
Characterizing Erosion and Deposition in and Around Riparian Vegetation Patches: Complex Flow Hydraulics, Sediment Supply, and Morphodynamic Feedbacks
Published 2024-02-01“…Sediment mobility within the patch was flow‐dependent and a function of velocity and turbulent kinetic energy. …”
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