Altered antibiotic transport in OmpC mutants isolated from a series of clinical strains of multi-drug resistant E. coli. by Hubing Lou, Min Chen, Susan S Black, Simon R Bushell, Matteo Ceccarelli, Tivadar Mach, Konstantinos Beis, Alison S Low, Victoria A Bamford, Ian R Booth, Hagan Bayley, James H Naismith

“…This results in the modulation of resistance to antibiotics, particularly cefotaxime. …”
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Aberrometric, Geometrical, and Biomechanical Characterization of Sound-Induced Vibrational Modes of the Living Human Cornea by Francisco J. Ávila, Óscar del Barco, Maria Concepción Marcellán, Laura Remón

“…Sound-induced corneal wavefront aberration maps were reconstructed as a function of sound frequency and isolated from the natural state. …”
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The Overlapping Biology of Sepsis and Cancer and Therapeutic Implications by Amit Kumar Tripathi, Yogesh Srivastava

“…The shared pathways between sepsis and cancer present unique opportunities for therapeutic intervention, including anti-inflammatory agents, immune checkpoint inhibitors, and metabolic modulators. Anti-inflammatory therapies, such as IL-6 and TNF-α inhibitors, show promise in mitigating inflammation, while immune checkpoint inhibitors like anti-PD-1 and anti-CTLA-4 antibodies are being explored to restore immune function in sepsis and enhance antitumor immunity in cancer. …”
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Multi-Scale Spatial Perception Attention Network for Few-Shot Hyperspectral Image Classification by Yang Li, Jian Luo, Haoyu Long, Qianqian Jin

“…A weighted CL-MixedLoss function (CL-MixedLoss) is proposed to solve the problem of imbalanced heterogeneous pixels in HSIs. …”
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Dextrose prolotherapy at varying concentrations ameliorates tendon injury via IGF-2R: an integrated study of Mendelian randomization and an animal model by Lina Zhou, Hui Liang, Yulin Chen, Kai Hu, Xixia Liu

“…In vivo studies demonstrated that tendon injury significantly impaired motor function in a rat model, with notable improvements observed after dextrose intervention. …”
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The Role and Clinical Significance of Vitamin D in Chronic Obstructive Pulmonary Disease by Sun M, Qian Y, Cai C, Zhang J, Qi R, Ma H, Ding Q, Wang S, Lv D

“…Clinical observational studies have demonstrated significant associations between vitamin D deficiency and increased exacerbation frequency, accelerated lung function decline, and elevated mortality risk. Mechanistically, we elucidate the pleiotropic effects of vitamin D in COPD pathogenesis, including its anti-inflammatory activity, suppression of oxidative stress, modulation of innate and adaptive immunity, inhibition of hepcidin, and reduction in pulmonary infection risk. …”
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GSF-YOLOv8: A Novel Approach for Fire Detection Using Gather-Distribute Mechanism and SimAM Attention by Caixiong Li, Dali Wu, Xing Zhang, Peng Wu

“…Lastly, we proposed a Focal-DIoU Loss to replace the original loss function, optimizing bounding box regression and improving localization accuracy. …”
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YOLOv10-LGDA: An Improved Algorithm for Defect Detection in Citrus Fruits Across Diverse Backgrounds by Lun Wang, Rong Ye, Youqing Chen, Tong Li

“…Lastly, we employ the Slide Loss function to adaptively adjust sample weights, focusing on hard-to-detect samples such as blurred features and subtle lesions in citrus disease images, effectively alleviating issues related to sample imbalance. …”
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Sunflower-based butterfly optimization algorithm with enhanced RNN for the harmonics elimination in multilevel inverter by V. Mohan, G. Krithiga, M. Thamil Alagan, V. Sathya

“…To determine Switching Angles (SA), an objective function is generated from the SHE problem. In this paper, the Sunflower based– Butterfly Optimization Algorithm (SF-BOA) is presented as a method for evaluating transcendental nonlinear equations using an MLI in a SHE approaches. …”
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Exploring Calcium Channels as Potential Therapeutic Targets in Blast Traumatic Brain Injury by Noemi Wachtler, Rory O’Brien, Barbara E. Ehrlich, Declan McGuone

“…This review aims to examine the role of calcium signaling in bTBI, focusing on the dual function of calcium channels as mediators and modulators of injury, and to explore therapeutic strategies targeting calcium homeostasis. …”
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High accuracy identification of maize seed varieties based on a lightweight improved YOLOv8 by Siqi Niu, Xiaolin Xu, Ao Liang, Yuliang Yun, Fengqi Hao, Jinqiang Bai, Wenyi Sheng, Dexin Ma

“…Lastly, the loss function was replaced with Inner_SIoU, which was more suitable for small-object detection tasks. …”
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A Contrastive-Augmented Memory Network for Anti-UAV Tracking in TIR Videos by Ziming Wang, Yuxin Hu, Jianwei Yang, Guangyao Zhou, Fangjian Liu, Yuhan Liu

“…In the second stage, a contrastive-augmented matching module (CAM), along with a refined contrastive loss function, is designed to enhance the discrimination ability of the tracker under the instruction of contrastive learning strategy. …”
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A Lightweight Citrus Object Detection Method in Complex Environments by Qiurong Lv, Fuchun Sun, Yuechao Bian, Haorong Wu, Xiaoxiao Li, Xin Li, Jie Zhou

“…Finally, the minimum-point-distance-based IoU (MPDIoU) loss function is utilized to optimize the boundary return mechanism, which speeds up model convergence and reduces the redundancy of bounding box regression. …”
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The roles of LncRNA CARMN in cancers: biomarker potential, therapeutic targeting, and immune response by Huafeng Liu, Xuewen Liu, Yanjun Lu

“…CARMN, originally identified for its function in cardiac tissues, has shown dysregulated expression in several tumor types, including cervical, breast, colorectal, and esophageal cancers. …”
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Investigation of the Characteristics of a Photodetector with a High Photocurrent when Transmitting Microwave Radio Signals Through an Optical Fiber by I. Yu. Tatsenko, T. K. Legkova, A. V. Ivanov, A. B. Ustinov

“…Research of microwave signal losses as a function of optical power.Materials and Methods. Experimental studies were carried out on created experimental schemes for studying the characteristics of the photodetector with modulated and unmodulated optical radiation. …”
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TMBO-AOD: Transparent Mask Background Optimization for Accurate Object Detection in Large-Scale Remote-Sensing Images by Tianyi Fu, Hongbin Dong, Benyi Yang, Baosong Deng

“…Furthermore, we introduce a novel separated loss function that strengthens both foreground and background consistencies. …”
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Integrated and improved YOLOv8 and triangulated network method for extracting indicators in open-pit mine mining areas by LI Tianwen, LI Gongquan, LI Juntao

“…Based on YOLOv8, the following improvements were made to obtain Mine-YOLO: the addition of an Efficient Multi-Scale Attention (EMA) module to enhance the model's recognition and segmentation accuracy of mining field boundaries; the inclusion of a Global Attention Mechanism (GAM) module to retain open-pit mining field feature data at a global scale, improving target recognition accuracy; and the optimization of the Focaler-IoU loss function to enhance the model's ability to distinguish positive samples. …”
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Group 2 innate lymphoid cells drive inhibitory synapse formation with lasting effects on learning and memory by Johannes Steffen, Divija Deshpande, Henning Peter Düsedau, Janna Schmitz, Caio Andreeta Figueiredo, Laura Velleman, Claudia Pitzer, Christoph S.N. Klose, Ildiko R. Dunay

“…This early immune-mediated modulation may have lasting effects on neuronal circuitry and cognitive functions that persist into adulthood, emphasizing the long-term implications of neuro-immune interactions for normal cognitive development and function.…”
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Engineering of photo-inducible binary interaction tools for biomedical applications by Yi-Tsang Lee, Lei Guo, Tien-Hung Lan, Tatsuki Nonomura, Gan Liu, Guolin Ma, Rui Wang, Yun Huang, Yubin Zhou

“…Collectively, through targeted ssrA insertions, PhoBITs offer versatile control over diverse protein functions, thereby expanding possibilities for optogenetic engineering and potential therapeutic applications.…”
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Death-associated protein kinase 1: a double-edged sword in health and disease by Xiuli Zhang, Yehuda G. Assaraf, Yao Lin

“…In light of its biological significance, several small molecule modulators of DAPK1 have been developed for therapeutic purposes and as probe compounds to enhance the mechanistic understanding of DAPK1-mediated biological functions. …”
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