The Intriguing Connection Between the Gut and Lung Microbiomes by Magdalena Druszczynska, Beata Sadowska, Jakub Kulesza, Nikodem Gąsienica-Gliwa, Ewelina Kulesza, Marek Fol

“…Mediated by immune interactions, metabolic byproducts, and microbial communities in both organs, this axis demonstrates how gut-derived signals, such as metabolites and immune modulators, can reach the lung tissue via systemic circulation, influencing respiratory function and disease susceptibility. …”
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MSOAR-YOLOv10: Multi-Scale Occluded Apple Detection for Enhanced Harvest Robotics by Heng Fu, Zhengwei Guo, Qingchun Feng, Feng Xie, Yijing Zuo, Tao Li

“…Furthermore, a Normalized Wasserstein Distance (NWD) loss function is proposed to effectively reduce missed detections of densely packed and overlapping targets. …”
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The stress-induced gene AtDUF569 positively regulates salt stress responses in Arabidopsis thaliana by Rizwana Begum Syed Nabi, Rupesh Tayade, Rupesh Deshmukh, Adil Hussain, Muhammad Shahid, Arjun Adhikari, Synan F. AbuQamar, Byung-Wook Yun

“…Recent reports have implicated the domain-of-unknown-function (DUF) proteins in plant stress responses. …”
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Music therapy and repetitive transcranial magnetic stimulation - nonpharmacological interventions in schizophrenia by Aleksandra Giba, Patrycja Niczyporuk, Izabela Zajkowska, Kamila Iłendo, Wiktor Królikiewicz, Rafał Marecki, Aleksandra Kicman

“…Conclusions: MT presents a safe and effective method for improving emotional well-being and immune function in cancer patients. Its impact on the gut-brain axis suggests a novel therapeutic pathway, warranting further investigation. …”
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MSHRNet: a multi-scale high-resolution network for land cover classification from high spatial resolution remote sensing images by Fang Chen, Zhihui Ou, Congrong Li, Lei Wang, Bo Yu

“…Additionally, we introduce a Laplacian operator-based boundary loss function (LBLoss) to further improve segmentation performance. …”
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Infrared Image Classification and Detection Algorithm for Power Equipment Based on Improved YOLOv10 by Xiu Ji, Zheyu Yue, Hongliu Yang, Zehong Zhang

“…To better handle the imbalance in sample distribution, the original Binary Cross-Entropy (BCE) loss function is modified to incorporate Focal Loss, aiming to enhance model performance by focusing more on hard-to-classify examples. …”
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Selenium Nanoparticles in Cancer Therapy: Unveiling Cytotoxic Mechanisms and Therapeutic Potential by Sumaira Anjum, Mariam Hashim, Maham Imran, Sundus Babur, Sanniah Adnan, Christophe Hano, Wisam Nabeel Ibrahim

“…Conclusion Selenium nanoparticles hold significant promise as a next‐generation cancer treatment modality. Their dual function—serving as both therapeutic agents and drug delivery vehicles—positions them as a powerful tool in precision oncology. …”
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YOLO-ALW: An Enhanced High-Precision Model for Chili Maturity Detection by Yi Wang, Cheng Ouyang, Hao Peng, Jingtao Deng, Lin Yang, Hailin Chen, Yahui Luo, Ping Jiang

“…Additionally, the Wise-IoU (Wise Intersection over Union) loss function optimizes bounding box learning, further improving the detection of peppers in occluded or background-similar scenarios. …”
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LLD-YOLO: A Low-Light Object Detection Algorithm Based on Dynamic Weighted Fusion of Shallow and Deep Features by Wenhao Cai, Yajun Chen, Xiaoyang Qiu, Meiqi Niu, Jianying Li

“…To address these challenges, we propose an improved neck structure, SRB-FPN, to achieve fine-grained cross-level semantic alignment and feature fusion, while also optimizing the regression loss function to develop LLD-YOLO, a detector specifically designed for low-light conditions. …”
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CRISPR/Cas9-Based therapeutics as a promising strategy for management of Alzheimer’s disease: progress and prospects by Mohamad Sultan Khan, Nousheen Qureshi, Rehan Khan, Young-Ok Son, Tariq Maqbool

“…It enables editing and modulation of gene function with an unparalleled precision and effectiveness. …”
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Protein Kinase A Regulates the Cell Cycle to Affect the Induction Rate in the Parthenogenetic Reproduction of the Silkworm, <i>Bombyx mori</i> by Fang Xu, Wei Yu, Chenkai Ma, Chengjie Hu, Chunguang Cui, Xin Du, Jine Chen, Linbao Zhu, Shaofang Yu, Xingjian He, Yongqiang Wang, Xia Xu

“…This versatile kinase exhibits regulatory functions in various biological processes including growth, division, and differentiation. …”
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Development of a multichannel hand-adaptive tactile stimulation device for somatotopic map of human hand in somatosensory cortex with fMRI by Yutong Wang, Di Luo, Lihua Ma, Luyao Wang, Jinglong Wu, Jian Zhang, Tianyi Yan

“…The 7T functional magnetic resonance imaging (fMRI) can provide a detailed somatotopic map. …”
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The regulatory effect of chitooligosaccharides on islet inflammation in T2D individuals after islet cell transplantation: the mechanism behind Candida albicans abundance and macrop... by Yayu Zhang, Xiaoguo Ji, Kunlin Chang, Hao Yin, Mengyao Zhao, Liming Zhao

“…First, 18S rDNA gene sequencing was performed on fecal samples from the ICT population, showing abnormally increased amount of Candida albicans, possibly causing pancreatic inflammation. Functional oligosaccharides responsible for regulating macrophage polarization and inhibiting the growth of Candida albicans were screened. …”
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Novel small non-coding RNAs of Epstein-Barr virus upregulated upon lytic reactivation aid in viral genomic replication and virion production by Sagarika Banerjee, Dipayan Bose, Steve Johnson, Jie Liu, Herbert Virgin, Erle S. Robertson

“…Furthermore, these ncRNAs interact with the OriLyt region of EBV genome, promoting viral DNA replication. Functional assays indicate that p7 and p8 enhance cell proliferation and inhibit apoptosis by modulating the p53 pathway and suppressing pro-apoptotic proteins. …”
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Identification of potential DAMPs released by necroptosis in estrogen-receptor positive breast cancer cells and their effect on macrophage differentiation by Banita Thakur, Rohit Verma, Aditya Dod, Anil K Ram, Yashwant Kumar, Alka Bhatia

“…Results: A total of 35 unique proteins with potential DAMP activity were identified in the IM. Functional and pathway analyses using PANTHER and DAVID revealed their involvement in immune regulation, metabolism, stress responses, and key pathways such as glycolysis, signaling, and inflammation. …”
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Identification of potential biomarkers and mechanisms for keloid disorder based on comprehensive bioinformatics analysis and machine learning algorithms by Bowen Zheng, Jianxiong Qiao, Xiaoping Yu, Hanghang Zhou, Anqi Wang, Xuanfen Zhang

“…These four biomarkers were proved to possess high diagnostic potential, and they were found to exhibit significant positive correlations with one another. Functional enrichment analysis indicated that the primary KEGG pathways associated with these biomarkers included “steroid hormone biosynthesis” and “cytokine–cytokine receptor interaction.” …”
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Role of DEAD/DEAH-box helicases in immunity, infection and cancers by Rex Devasahayam Arokia Balaya, Saptami Kanekar, Shreya Kumar, Richard K. Kandasamy

“…DEAD-box proteins predominantly facilitate localized non-processive RNA duplex destabilization, whereas DEAH-box helicases mediate processive RNA translocation and unwinding. This functional dichotomy is attributed to Asp-to-His substitution in the DEAH motif, which modulates ATP hydrolysis and conformational dynamics. …”
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Analysis of Antioxidant Activity and Volatile Components in Rapeseed Flower-Enriched Persimmon Wine by Zhijie Li, Kaishuo Sun, Yanyan Wang, Fang Yu, Zhiwen Liu

“…This study employed Luotian sweet persimmons and Brassica napus (rapeseed) as core ingredients for producing functional fermented wine. Using GC-MS, rapeseed polysaccharides were subjected to trifluoroacetic acid hydrolysis and then derivatized via silylation for qualitative analysis of their monosaccharide composition. …”
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Lactoferrin promotes intestinal stem cell‐mediated epithelial regeneration by activating Wnt signaling by Weiru Yu, Yingying Lin, Yao Lu, Yuqi Wang, Dan Zhang, Heng Quan, Yujia Luo, Yuning Zhang, Zhengqiang Jiang, Juan Chen, Yixuan Li, Huiyuan Guo

“…Lactoferrin (LF) is a natural milk‐abundant protein with several gut health‐related functions such as antibacterial and immunoregulation activities, thus protecting intestine from damage. …”
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Germin-like protein 1 interacts with proteasome regulator 1 to regulate auxin signaling by controlling Aux/IAA homeostasis by Faqing Xu, Yongqiang Yu, Bin Guan, Tongda Xu, Zhihong Xu, Hongwei Xue

“…Proteasome regulator 1 (PTRE1), a positive regulator of proteasome activity, has been implicated in auxin-mediated proteasome suppression; however, the mechanism by which auxin modulates PTRE1 function remains unclear. Here, we demonstrate that auxin promotes the interaction between germin-like protein 1 (GLP1) and PTRE1, facilitating PTRE1 retention at the plasma membrane. …”
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