ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2. by Matthew J Girgenti, Joseph J LoTurco, Brady J Maher

“…Although the molecular function of ZNF804a is unknown, the amino acid sequence is predicted to contain a C2H2-type zinc-finger domain and suggests ZNF804a plays a role in DNA binding and transcription. …”
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Immunomodulator Testing on Ethanol Extract of Gynura procumbens Leaves to Mus musculus Adaptive Immune System: in Vitro Study by Dinia Rizqi Dwijayanti, Muhaimin Rifa'i

“…Immunomodulator is a substance that has an ability to modulate the activity and function of immune system. …”
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A primary insight into gut microbiome, MicroRNA and stemness, in a PCOS rat model by Fereshteh Esfandiarinezhad, Xiaoshu Zhan, Seang Lin Tan, Julang Li, Benjamin K. Tsang

“…These findings imply a potential link between gut microbiome dysbiosis and increased ovarian stemness in PCOS, suggesting that the gut microbiome may contribute to ovarian dysfunction through modulation of stem cell activity. Understanding this interaction could provide novel insights into therapeutic targets in restoring ovarian function in PCOS patients.…”
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News Text Classification Method and Simulation Based on the Hybrid Deep Learning Model by Ningfeng Sun, Chengye Du

“…Then, on the basis of systematic research on text classification, deep learning, and news text classification theories, a deep learning-based network news text classification model is constructed, and the function of each module is introduced in detail, which will help the future news text classification of application and improvement provide theoretical basis. …”
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L-thyroxine modifies nephrotoxicity by regulating the apoptotic pathway: The possible role of CD38/ADP-ribosyl cyclase-mediated calcium mobilization. by Tarek El-Hamoly, Dina M El-Sharawy, Marwa S El Refaye, Sahar S Abd El-Rahman

“…Remarkably, pretreatment with L-TH (1μg/kg) ameliorated the elevated kidney function biomarkers, oxidative stress and protected the renal tissue from the subsequent cellular damage. …”
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Research on a UAV-View Object-Detection Method Based on YOLOv7-Tiny by Yuyang Miao, Xihan Wang, Ning Zhang, Kai Wang, Lianhe Shao, Quanli Gao

“…The algorithm’s performance in handling object occlusion and multi-scale detection is enhanced by introducing the VarifocalLoss loss function and improving the feature fusion network to BiFPN. …”
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Integrative metabolomics and proteomics reveal the effects and mechanisms of Salvia miltiorrhiza in alleviating traumatic blood stasis syndrome by Pei Guo, Xin Wang, Qi Chen, Xufeng Dong, Zhihua Qin, Jiaguo Liu

“…We established a TBSS model in cats and examined the muscle swelling rate (MSR), pain index, coagulation index, hematological parameters, inflammatory factors, and platelet function levels to assess the effects of SM. Subsequently, integrative metabolomics and proteomics were employed to elucidate the effects and mechanisms of SM in alleviating TBSS. …”
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Effects of exogenous sucrose on root nitrogen uptake in apple at sub-low root-zone temperature by Xiaoping Zhao, Hanyu Liu, Lijie Li, Deguo Lyu

“…Abstract Sub-low soil temperature in spring can cause stress to the apple roots, reducing root function and inhibiting nitrogen (N) uptake. Exogenous sucrose can protect plants from low temperature stress, however, the role of sucrose in regulating the N uptake in apple roots at sub-low temperature is unclear. …”
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Interaction profiling of cow milk metabolites against human Renin-Angiotensin System (RAS) proteins by Neelam Krishna, Shraddha Vishwakarma, Pramod Katara

“…Based on binding affinity, we can predict whether the specific metabolites with effective binding scores modulate the function of specific RAS proteins. …”
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A Study on an Improved Generative Adversarial Network Model for Super-Resolution Image Reconstruction by Ximin Qu, Cheng Peng

“…Additionally, the joint perceptual-adversarial-content loss function of the SRGAN model balances reconstruction accuracy and visual quality. …”
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Regulation of miRNA transcription in macrophages in response to Candida albicans. by Claire E Monk, György Hutvagner, J Simon C Arthur

“…These results suggest that miR-455, miR-125, miR-146 and miR-155 may play important roles in regulating macrophage function following PRR stimulation.…”
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Dynamic Regulation of HIF1α and Oxygen-Sensing Factors in Cyclic Bovine Corpus Luteum and During LPS Challenge by Luiz Antonio Berto Gomes, Olivia Eilers Smith, Heinrich Bollwein, Mariusz Pawel Kowalewski

“…LPS treatment affected <i>PHD1</i> and <i>PHD3</i> expression, while increasing endothelial pro-inflammatory factors <i>ICAM1</i> and <i>NFκB</i>, suggesting vascular inflammation and modulated oxygen sensing. These findings reveal new insights into the spatio-temporal expression of HIF1α-regulating factors in the CL, highlighting their potential role in controlling luteal function, detailing their cellular compartmentalization, and the effects of LPS-mediated inflammatory responses.…”
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Protection of LPS-induced intestinal injury in goslings by polysaccharide of Atractylodes macrocephala Koidz based on 16S rRNA and metabolomics analysis. by Wanyan Li, Baili Lu, Shirou Pan, Shuaifei Bai, Jiayu He, Bingxin Li, Nan Cao, Xinliang Fu, Junhao Wei, Ying Chen, Yunmao Huang, Yunbo Tian, Danning Xu

“…Overall, PAMK could alleviate LPS induced intestinal injury by enhancing intestinal barrier function, optimizing gut microbiota composition, and regulating metabolic signaling pathways. …”
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Vitamin D, Calcium, Parathyroid Hormone, and Sex Steroids in Bone Health and Effects of Aging by Hitesh Kumar Bhattarai, Shreya Shrestha, Kabita Rokka, Rosy Shakya

“…Sex hormones regulate bone modeling at an early age and remodeling later in life. Loss of ovarian function and a decrement in the level of production of estrogen are marked by bone loss in elderly women. …”
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Effect of resveratrol supplementation on lipid metabolism in healthy and obese cats by Jung Eun Yun, Seung Rok Kang, Jae Young Kim, Hyun Joong Kim, Motoo Kobayashi, Toshiro Arai

“…Resveratrol (RSV), a natural plant polyphenol, modulates the expression of anti-inflammatory factors. …”
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Agmatine Mitigates Diabetes-Related Memory Loss in Female Mice by Targeting I₂/I₃ Imidazoline Receptors and Enhancing Brain Antioxidant Defenses by Luis E. Cobos-Puc, Hilda Aguayo-Morales

“…Agmatine treatment improved cognitive function and reversed the biochemical alterations. …”
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Pirfenidone for Idiopathic Pulmonary Fibrosis and Beyond by Alberto Aimo, Giosafat Spitaleri, Dari Nieri, Laura Maria Tavanti, Claudia Meschi, Giorgia Panichella, Josep Lupón, Francesco Pistelli, Laura Carrozzi, Antoni Bayes-Genis, Michele Emdin

“…Myocardial fibrosis is a common feature of several heart diseases and the progressive deposition of extracellular matrix due to a persistent injury to cardiomyocytes may trigger a vicious cycle that leads to persistent structural and functional alterations of the myocardium. No primarily antifibrotic medications are used to treat patients with heart failure. …”
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Electrostatics of salt-dependent reentrant phase behaviors highlights diverse roles of ATP in biomolecular condensates by Yi-Hsuan Lin, Tae Hun Kim, Suman Das, Tanmoy Pal, Jonas Wessén, Atul Kaushik Rangadurai, Lewis E Kay, Julie D Forman-Kay, Hue Sun Chan

“…The electrostatic nature of these features complements ATP’s involvement in π-related interactions and as an amphiphilic hydrotrope, underscoring a general role of biomolecular condensates in modulating ion concentrations and its functional ramifications.…”
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Salt Stress Mitigation and Field-Relevant Biostimulant Activity of Prosystemin Protein Fragments: Novel Tools for Cutting-Edge Solutions in Agriculture by Martina Chiara Criscuolo, Raffaele Magliulo, Valeria Castaldi, Valerio Cirillo, Claudio Cristiani, Andrea Negroni, Anna Maria Aprile, Donata Molisso, Martina Buonanno, Davide Esposito, Emma Langella, Simona Maria Monti, Rosa Rao

“…Here we investigated the effects of three previously characterized Prosystemin-derived functional peptide fragments as protective agents against salt stress and as biostimulants modulating tomato yield and quality traits. …”
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Light Exposure as a Tool to Enhance the Regenerative Potential of Adipose-Derived Mesenchymal Stem/Stromal Cells by Kaarthik Sridharan, Tawakalitu Okikiola Waheed, Susanne Staehlke, Alexander Riess, Mario Mand, Juliane Meyer, Hermann Seitz, Kirsten Peters, Olga Hahn

“…Photobiomodulation (PBM) utilizes different wavelengths of light to modulate cellular functions and has emerged as a promising approach in regenerative medicine. …”
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