Interdecadal Variability of Summer Precipitation Efficiency in East Asia by Jian Wang, Shu Gui, Anqi Ma, Ruowen Yang, Qi Zhang

“…Two major modes of summertime precipitation efficiency are identified using Empirical Orthogonal Function (EOF) analysis. The leading EOF mode (EOF1) has a dipole pattern that reveals the variations of mean precipitation efficiency. …”
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Clostridium butyricum ameliorates indomethacin-induced enteropathy by promoting MUC2 secretion via suppressing the Notch pathway by Lanping Zhu, Yang Luo, Yaxin Liu, Siyuan Sun, Junjie Yuan, Lijun Zhang, Weilong Zhong, Shuang Ma, Zihan Yu, Jinjie Zhou, Xin Chen, Jingwen Zhao

“…Caco2 cells were stimulated with IND to evaluate the effect of CB supernatant (CBS) on the intestinal barrier function, and LS174T cells were used to validate the modulatory action of CBS on the Notch signaling pathway. …”
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Identification of hypertension gene expression biomarkers based on the DeepGCFS algorithm. by Zongjin Li, Liqin Tian, Libing Bai, Zeyu Jia, Xiaoming Wu, Changxin Song

“…This algorithm utilizes a graph network to represent the interaction information between genes, builds a GNN model, designs a loss function based on link prediction and self-supervised learning ideas for training, and allows each gene node to obtain a feature vector representing global information. …”
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Understanding embolus transport and source to destination mapping of thromboemboli in hemodynamics driven by left ventricular assist device by Sreeparna Majee, Akshita Sahni, Jay D. Pal, Erin E. McIntyre, Debanjan Mukherjee

“…We conduct systematic numerical experiments to establish that our framework can quantify the source-to-destination transport patterns of thromboemboli as a function of: LVAD outflow graft anastomosis, LVAD operating pulse modulation, thromboembolus sizes, and origin locations of emboli. …”
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Fault localization for automatic train operation based on the adaptive error locating array algorithm by Yanpeng Zhang, Yuxiang Cao

“…The research results can offer useful guidance for verifying the integrity and reliability of the ATO function and contribute to the intrinsic safety for rail transit.…”
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DP-YOLO: A Lightweight Real-Time Detection Algorithm for Rail Fastener Defects by Lihua Chen, Qi Sun, Ziyang Han, Fengwen Zhai

“…Fourth, to improve multi-scale adaptability, we replace the standard loss function with Alpha-IoU, enhancing model robustness. …”
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TRPC3 contributes to cyclophosphamide-induced cystitis progression by enhancing bladder fibrosis through activation of the TGF-β/smad pathway by Ruixiang Luo, Wenshuang Li, Junlong Huang, Zheng Liu, Chi Zhang, Honglu Ding, Jialiang Chen

“…The study assessed mechanical pain sensitivity and bladder function through von Frey testing and cystometry.ResultsSignificant findings revealed TRPC3 RNA and protein expression was markedly upregulated in cystitis rats. …”
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Etoricoxib–NLC Mitigates Radiation-Induced Ovarian Damage in Rats: Insights into Pro-Inflammatory Cytokines, Antioxidant Activity, and Hormonal Responses by Sahar Khateeb

“…ETO-NLC shows promise as an effective strategy for attenuating radiation-induced ovarian damage, highlighting the need for further research to enhance therapeutic interventions aimed at preserving ovarian function during cancer treatment.…”
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Successful treatment with sintilimab for SMARCA4-deficient non-small cell lung carcinoma: two case reports by Liwen Wang, Hua Ke, Chengdi Wang, Ke Wang

“…By disrupting histone-DNA contacts, this complex modulates gene expression patterns, and accumulating evidence suggests its tumor suppressor function. …”
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ApoE receptor 2 regulates synapse and dendritic spine formation. by Sonya B Dumanis, Hyun-Jung Cha, Jung Min Song, Justin H Trotter, Matthew Spitzer, Ji-Yun Lee, Edwin J Weeber, R Scott Turner, Daniel T S Pak, G William Rebeck, Hyang-Sook Hoe

“…<h4>Conclusions/significance</h4>These results suggest that ApoEr2 plays important roles in structure and function of CNS synapses and dendritic spines, and that these roles are modulated by cytoplasmic adaptor proteins X11α and PSD-95.…”
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RMS Modeling and Control of a Grid-Forming E-STATCOM for Power System Stability in Isolated Grids by José Luis Rodriguez-Amenedo, Miguel E. Montilla-DJesus, Santiago Arnaltes, Francisco Arredondo

“…Additionally, an exciter with a nonlinear modulation function is introduced to optimize voltage regulation and reactive power support. …”
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Effect of Regular Physical Exercise on Gut Microbiota and Depressive Behaviors in Rats by Liangju Sheng, Yuxuan Wang, Anqi Jiang, Yan Zhou, Hong Zhou

“…Regular physical exercise could alleviate depressive-like behaviors by modulating the species and function of the gut microbiota.…”
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In-vivo Hepatoprotective Evaluation of Sicyos edulis on Wistar Albino Rats by Karisma Borah, Devid Chutia, Manodeep Chakraborty, Ananya Bhattacharjee, Nihar Ranjan Bhuyan

“…However, during biological processes, the abnormality occurs in the liver, which becomes a significant global health burden in humans, characterised by loss of synthetic function, breakdown of blood, irregular vitamin K, and localised, permanent changes to parenchymal cells. …”
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3-D Model Extraction Network Based on RFM-Constrained Deformation Inference and Self-Similar Convolution for Satellite Stereo Images by Wen Chen, Hao Chen, Shuting Yang

“…We construct the self-similar convolution module by utilizing the self-similarity characteristics existing in the target itself. …”
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Involvement of a 1-Cys peroxiredoxin in bacterial virulence. by Gilberto Hideo Kaihami, José Roberto Fogaça de Almeida, Suelen Silvana dos Santos, Luis Eduardo Soares Netto, Sandro Rogério de Almeida, Regina Lúcia Baldini

“…LsfA belongs to the poorly studied Prx6 subfamily of peroxiredoxins. The function of these peroxiredoxins has not been characterized in bacteria, and their contribution to host-pathogen interactions remains unknown. …”
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Photoaging Protective Effects of Quercitrin Isolated from ‘Green Ball’ Apple Peel by Eun-Ho Lee, Junhyo Cho, In-Kyu Kang

“…Premature skin aging, also known as photoaging, refers to the changes in the structure and function of the skin caused by chronic sun exposure. …”
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Novel approaches targeting α-Synuclein for Parkinson's Disease: Current progress and future directions for the disease-modifying therapies by David Baggett, Alex Olson, Mayur S. Parmar

“…The hallmark pathological feature of PD is the accumulation and aggregation of α-Synuclein (α-Syn), a protein involved in synaptic function and neuronal survival. The formation of α-Syn aggregates, also known as Lewy bodies and Lewy neurites, leads to neuronal dysfunction and death, resulting in PD's characteristic motor and non-motor symptoms. …”
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Bone marrow mesenchymal stem cell-derived vascular endothelial growth factor attenuates cardiac apoptosis via regulation of cardiac miRNA-23a and miRNA-92a in a rat model of myocar... by Yi-Sun Song, Hyun-Woo Joo, In-Hwa Park, Guang-Yin Shen, Yonggu Lee, Jeong Hun Shin, Hyuck Kim, Kyung-Soo Kim

“…Bone marrow-mesenchymal stem cell (BM-MSC) therapy improves the recovery of cardiac function after myocardial infarction (MI); however, the underlying molecular mechanisms are not completely understood. …”
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YOLOv8-BaitScan: A Lightweight and Robust Framework for Accurate Bait Detection and Counting in Aquaculture by Jian Li, Zehao Zhang, Yanan Wei, Tan Wang

“…The key innovations are as follows: (1) By incorporating the channel prior convolutional attention (CPCA) into the final layer of the backbone, the model efficiently extracts spatial relationships and dynamically allocates weights across the channel and spatial dimensions. (2) The minimum points distance intersection over union (MPDIoU) loss function improves the model’s localization accuracy for bait bounding boxes. (3) The structure of the Neck network is optimized by adding a tiny-target detection layer, which improves the recall rate for small, distant bait targets and significantly reduces the miss rate. (4) We design the lightweight detection head named Detect-Efficient, incorporating the GhostConv and C2f-GDC module into the network to effectively reduce the overall number of parameters and computational cost of the model. …”
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The light chains of microtubule-associated proteins MAP1A and MAP1B interact with α1-syntrophin in the central and peripheral nervous system. by Heike Fuhrmann-Stroissnigg, Rainer Noiges, Luise Descovich, Irmgard Fischer, Douglas E Albrecht, Fatiha Nothias, Stanley C Froehner, Friedrich Propst

“…Our findings add to a growing body of evidence that classical MAPs are likely to be involved in signal transduction not only by directly modulating microtubule function, but also through their interaction with signal transduction proteins.…”
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