A Two-eRNA-Based Signature Can Impact the Immune Status and Predict the Prognosis and Drug Sensitivity of Lung Adenocarcinoma by Li Wang, Shao-quan Zhou, Yu Zhou, Jia-xi Lu

“…Taken together, our findings indicated PCBP1-AS1 as a function modulator in LUAD development. In addition, we constructed a robust immune-related eRNA signature which might be a clinical prognosis factor for LUAD patients.…”
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The correlations of serum uric acid with lean mass, fat mass and grip strength in adolescents aged 12-19 years by Feng Xu, Jianjun Shen, Zhongxin Zhu

“…BackgroundSerum uric acid (sUA) has emerged as an intriguing modulator of body composition and physical function, yet its complex associations with musculoskeletal parameters during the critical period of adolescence remain incompletely characterized. …”
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Airport Clearance Detection Based on Vision Transformer and Multi-Scale Feature Fusion by Yutong Chen, Yufen Liu, Zhixiong Guo, Qiang Gao

“…Then, add the Vision Transformer module to capture more contextual information. Finally, improve the loss function to enhance the ability of bounding box regression processing. …”
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Neuroprotective Effects of Ascorbic Acid, Vanillic Acid, and Ferulic Acid in Dopaminergic Neurons of Zebrafish by Fatemeh Hedayatikatouli, Michael Kalyn, Dana Elsaid, Herman Aishi Mbesha, Marc Ekker

“…<b>Methods/Results:</b> Following exposure and qPCR and immunohistochemical analyses, ascorbic acid enhanced DAnergic function, indicated by an upregulation of the dopamine transporter (<i>dat</i>) gene and increased eGFP+ DAnergic cells, suggesting improved dopamine reuptake and neuroprotection. …”
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HnRNP L is essential for peripheral T cell proliferation and survival by Tristan L. A. White, Devin J. Henry, Sean D. A. Roberts, Ye Jin, Yi-Nan Gong, Penelope A. Morel

“…MethodsTo better understand the role of hnRNP L in modulating peripheral T cell trafficking and function, we analyzed T survival and activation in newly generated CD4Cre x hnRNP LFl/Fl (KO) mice. …”
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Semiotic- Semantic Analysis of Peikar-e Farhād by Teymoor Malmir, Shahla Naseri

“…The utilization of this narrative framework in which painting is animated function as a medium of protest against how the presence of women in the society has been shaped. …”
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Theoretical analysis of low power optogenetic control of synaptic plasticity with subcellular expression of CapChR2 at postsynaptic spine by Nripesh Dixit, Gur Pyari, Himanshu Bansal, Sukhdev Roy

“…The analysis provides a new means of direct optogenetic control of $${Ca}^{2+}$$ -based synaptic plasticity, better understanding of learning and memory processes, and opens prospects for targeted therapeutic interventions to modulate synaptic function and address various neurological disorders.…”
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The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively. by Irina Cornaciu, Andras Boeszoermenyi, Hanna Lindermuth, Harald M Nagy, Ines K Cerk, Catharina Ebner, Barbara Salzburger, Astrid Gruber, Martina Schweiger, Rudolf Zechner, Achim Lass, Robert Zimmermann, Monika Oberer

“…Our data provide insights into the structure-function relationship of ATGL and indicate higher structural similarities in the N-terminal halves of mammalian patatin-like phospholipase domain containing proteins, (PNPLA1, -2,- 3 and -5) than originally anticipated.…”
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Fumonisin B₁ Exposure Causes Intestinal Tissue Damage by Triggering Oxidative Stress Pathways and Inducing Associated CYP Isoenzymes by Changyu Cao, Weiping Hua, Runxi Xian, Yang Liu

“…For investigating FB₁-mediated intestinal toxicity, we assessed the function of FB₁ exposure in quail intestines and explored its possible molecular mechanisms. …”
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Characterization of zebrafish rod and cone photoresponses by Shinya Sato, Vladimir J. Kefalov

“…These studies provide a foundation for the use of zebrafish rods and cones to study the fundamental mechanisms that modulate the function of vertebrate photoreceptors in health and disease.…”
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The NSL complex regulates housekeeping genes in Drosophila. by Kin Chung Lam, Friederike Mühlpfordt, Juan M Vaquerizas, Sunil Jayaramaiah Raja, Herbert Holz, Nicholas M Luscombe, Thomas Manke, Asifa Akhtar

“…In flies, it is involved in the regulation of X-chromosomal and autosomal genes as part of the MSL and the NSL complexes, respectively. While the function of the MSL complex as a dosage compensation regulator is fairly well understood, the role of the NSL complex in gene regulation is still poorly characterized. …”
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ACE inhibitory casein peptide lowers blood pressure and reshapes gut microbiota in a randomized double blind placebo controlled trial by Kexin Li, Peng Jiang, Shuangqi Li, Jin Sun, Ce Qi

“…The antihypertensive mechanisms may involve (1) HCP-C7C12 acting as an angiotensin-converting enzyme inhibitor, reducing angiotensin II production, and (2) modulating amino acid abundance such as L-Arginine, L-valine, leucine, and phenylalanine, resulting in anti-inflammatory and antioxidant effects that improve endothelial function. …”
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Comparison of muscle synergies for running between different foot strike patterns. by Koji Nishida, Shota Hagio, Benio Kibushi, Toshio Moritani, Motoki Kouzaki

“…Six muscle synergies were extracted from all conditions, and each synergy had a specific function and a single main peak of activity in a cycle. …”
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DLK-1/p38 MAP Kinase Signaling Controls Cilium Length by Regulating RAB-5 Mediated Endocytosis in Caenorhabditis elegans. by Aniek van der Vaart, Suzanne Rademakers, Gert Jansen

“…Several studies indicate that cilium length and function can be modulated by environmental cues. As a model, we study a C. elegans mutant that carries a dominant active G protein α subunit (gpa-3QL), resulting in altered IFT and short cilia. …”
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Constructing a web recommender system using web usage mining and user’s profiles by T. Mombeini, A. Harounabadi, J. Rezaeian Sheshdeh

“…Web usage mining was designed to function on web server records, which are included in user search results. …”
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Establishment of a stellate ganglion regulation model in mice using infrared polarized light irradiation by Kaixuan Zhao, Haoyue Zhang, Yanbo Liu, Ying Zhou, Juan Zhi, Qianyu Wang, Dong Yang

“…ObjectiveTo explore the feasibility of establishing a mouse stellate ganglion (SG) regulation model through infrared polarized light (IPL) irradiation of the SG, and preliminarily evaluate its effects on SG function and related physiological indicators. Surgery, and IPL groups, with 8 mice in each group. …”
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DAHD-YOLO: A New High Robustness and Real-Time Method for Smoking Detection by Jianfei Zhang, Chengwei Jiang

“…The wise–powerful intersection over union (Wise-PIoU) is adopted as the new bounding box regression loss function, resulting in quicker convergence speed and improved detection outcomes. …”
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A Raman-Pumped Dispersion and Nonlinearity Compensating Fiber For Fiber Optic Communications by Elham Bidaki, Shiva Kumar

“…The proposed inline OBP module consists of an optical phase conjugator, amplifiers and a Raman pumped DCF. …”
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Hypoxia Induced Downregulation of Na+/H+ Exchanger-1 Activity Decreases Tumor Cell Proliferation by Gül Şimşek, Hilmi Burak Kandilci

“…Objectives: Hypoxia and acidosis are the hallmarks of proliferative tumor microenvironment which can modulate the expression and function of Na+/H+ exchanger-1 (NHE1) via hypoxia inducible factor 1 (Hif). …”
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Tetraspanin (TSP-17) protects dopaminergic neurons against 6-OHDA-induced neurodegeneration in C. elegans. by Neda Masoudi, Pablo Ibanez-Cruceyra, Sarah-Lena Offenburger, Alexander Holmes, Anton Gartner

“…We show that TSP-17 is expressed in dopaminergic neurons and provide genetic, pharmacological and biochemical evidence that it inhibits DAT-1, thus leading to increased 6-OHDA uptake in tsp-17 loss-of-function mutants. TSP-17 also protects against toxicity conferred by excessive intracellular dopamine. …”
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