Multidimensional Regulatory Mechanisms and Targeting Strategies of the eEF1 Family in RNA Virus Infection by Xin Wang, Kaituo Liu, Xiaoquan Wang, Xiufan Liu

“…The eukaryotic translation elongation factor 1 (eEF1) family exhibits critical roles in RNA viral infection beyond its canonical function in protein synthesis. This review analyzes the structural characteristics of eEF1A and the eEF1B complex, and their regulatory mechanisms during viral infection. eEF1A impacts viral replication by stabilizing viral RNA-dependent RNA polymerase (RdRp) complexes, modulating genomic RNA synthesis, and facilitating viral assembly through cytoskeletal regulation. eEF1B subunits contribute through enhancing viral mRNA translation, regulating nuclear transport of viral components, and mediating post-translational modifications. …”
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Plasminogen influence on the PAI-1 release by human platelets by O. I. Yusova, T. V. Grinenko, T. F. Drobot’ko, A. O. Tykhomyrov

“…Our findings may be of importance for elucidating the pathogenetic mechanisms of many diseases associated with abnormally enhanced platelet function and PAI-1-related disorders.…”
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Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease by Fredrik EO Holmberg, Jakob B Seidelin, Xiaolei Yin, Benjamin E Mead, Zhixiang Tong, Yuan Li, Jeffrey M Karp, Ole H Nielsen

“…Successful engraftment in experimental colitis models suggests that intestinal stem cell transplantation could constitute a novel treatment strategy to re‐establish mucosal barrier function in patients with severe disease. Intestinal stem cells can be grown in vitro in organoid structures, though only a fraction of the cells contained are stem cells with regenerative capabilities. …”
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Effects of Physical Exercise on Individual Resting State EEG Alpha Peak Frequency by Boris Gutmann, Andreas Mierau, Thorben Hülsdünker, Carolin Hildebrand, Axel Przyklenk, Wildor Hollmann, Heiko Klaus Strüder

“…Previous research has shown that both acute and chronic physical exercises can induce positive effects on brain function and this is associated with improvements in cognitive performance. …”
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Ultra-Wide-Field Long-Wave Infrared System via Hybrid Refractive–Reflective Structure and Field of View Stitching by Yiruo Wang, Shan Mao, Jianlin Zhao

“…The system exhibits excellent imaging performance, with a modulation transfer function (MTF) exceeding 0.5 at 17 lp/mm, the blur spot remaining within the airy disk limit, and the energy concentration exceeding 60% at 15 μm: the tolerance design meets the imaging requirements. …”
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Smart Agricultural Pest Detection Using I-YOLOv10-SC: An Improved Object Detection Framework by Wenxia Yuan, Lingfang Lan, Jiayi Xu, Tingting Sun, Xinghua Wang, Qiaomei Wang, Jingnan Hu, Baijuan Wang

“…The Convolutional Block Attention Module is employed to improve feature representation and attention focus. …”
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LRA-UNet: A Lightweight Residual Attention Network for SAR Marine Oil Spill Detection by Yu Cai, Jingjing Su, Jun Song, Dekai Xu, Liankang Zhang, Gaoyuan Shen

“…Additionally, we design a joint loss function that incorporates Sobel-based edge information, emphasizing boundary features during training to enhance edge sharpness. …”
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Putrescine treatment has a higher effect on 5mC DNA methylation profile of wheat leaves under white than under blue light conditions by Imre Majláth, Kinga Benczúr, Altafur Rahman, Tibor Janda, István Likó, János Kádas, Magda Pál

“…Abstract Polyamines play a pivotal role in plant growth and development by modulating primary metabolism and gene expression patterns. …”
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The gut microbiota-mediated ferroptosis pathway: a key mechanism of ginsenoside Rd against metabolism-associated fatty liver disease by Wenjing Liu, Xian Zhou, Liyu Xiao, Xiaolan Huang, Dennis Chang, Xiaomei Zhong, Minjie Zeng, Yanfang Xian, Yanfang Zheng, Wei Huang, Rui Huang, Mingqing Huang

“…It also significantly reduced the abundances of Faecalibaculum rodentium while increasing Muribaculum intestinale, with its functional role being relevant to lipid metabolism regulation. …”
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Study on mechanism of Miao medicine Xinnao Liantong capsule in treatment of myocardial ischemia diseases based on network pharmacology and molecular docking by Yuan Yao, Huan Zhang, Na Zhan, Yong Deng, Jianyong Zhang

“…A ''herb-active components-intersection targets'' network was constructed, and protein-protein interaction analyses were performed using Cytoscape and STRING. Functional enrichment analyses were performed using DAVID, and molecular docking was employed to validate core component-target interactions. …”
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Current Endocrine Therapy in Hormone-Receptor-Positive Breast Cancer: From Tumor Biology to the Rationale for Therapeutic Tunning by Oana Maria Burciu, Adrian-Grigore Merce, Simona Cerbu, Aida Iancu, Tudor-Alexandru Popoiu, Ionut Marcel Cobec, Ioan Sas, Gabriel Mihail Dimofte

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Neuraminidase activity and specificity of influenza A virus are influenced by haemagglutinin-receptor binding by Jimmy Chun Cheong Lai, Herath M. T. K. Karunarathna, Ho Him Wong, Joseph S. M. Peiris, John M. Nicholls

“…Although the balance between two proteins functions has been found to be crucial for viral fitness, the interplay between the proteins has not been well established. …”
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Effects of a Multimodal Immersive Virtual Reality Intervention on Heart Rate Variability in Adults with Post-COVID-19 Syndrome by Neus Cano, Oscar Casas, Mar Ariza, Olga Gelonch, Yemila Plana, Bruno Porras-Garcia, Maite Garolera

“…Reduced heart rate variability (HRV) serves as a biomarker for ANS function. Few studies have assessed HRV modulations over treatment in PCC patients. …”
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Heightened cholesterol 25-hydroxylase expression in aged lung during Streptococcus pneumoniae by David G. Thomas, David G. Thomas, Jianjun Yang, Soo Jung Cho, Soo Jung Cho, Heather Stout-Delgado

“…Changes in lipid metabolism in AM can alter cellular function and biology. Impaired metabolism can contribute to excessive lipid accumulation and pro-inflammatory signaling. …”
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PB-STR: A spatiotemporal transformer network for multi-behavior recognition of pigs by Yufan Hu, Xiaobo Wang, Rui Mao, Yusen Guo, Xianyao Zhu, Meili Wang

“…It develops a Time Series Prediction Module (UnetTSF) and a Context Anchor Attention (CAA) module, enhancing the PB-STR framework's ability to capture feature evolution over time and fully utilize contextual information. …”
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DBDB: de-bimodal defocus blur in joint infrared-visible imaging by Zhe Cao, Lixin Xu, Jin Zhang, Biwen Yang, Kaizheng Chen, Ruiheng Zhang

“…To address these issues, we propose the first de-bimodal defocus blur (DBDB) method, which consists of a low-frequency semantic hold (LSH) module with a pre-trained infrared model and a cross-modal complementary feature induction (CCFI) module driven by a max-min blur entropy loss. …”
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Enabling Equalization and Soft Decision by k-Means for VCSEL-Based PAM-4 Optical Interconnection by Lin Sun, Jiangbing Du, Ke Xu, Bo Liu, Zuyuan He

“…As for vertical-cavity surface-emitting lasers (VCSEL)-based optical pulse amplitude modulation (PAM) interconnection system, apart from the universal signal distortions like Gaussian noise and fiber dispersion, direct modulation of VCSEL specially induces level nonlinearity and level-dependent noise. …”
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Crosstalk between Platelets and the Immune System: Old Systems with New Discoveries by Conglei Li, June Li, Yan Li, Sean Lang, Issaka Yougbare, Guangheng Zhu, Pingguo Chen, Heyu Ni

“…Platelets express several functional Toll-like receptors (TLRs), such as TLR-2, TLR-4, and TLR-9, which may potentially link innate immunity with thrombosis. …”
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Memristors Based on Ni(II)‐tetraaza[14]annulene Complexes: Toward an Unconventional Resistive Switching Mechanism by Andrzej Sławek, Lulu Alluhaibi, Ewelina Kowalewska, Gisya Abdi, Tomasz Mazur, Agnieszka Podborska, Krzysztof Mech, Marianna Marciszko‐Wiąckowska, Alexey Maximenko, Konrad Szaciłowski

“…Operando X‐ray fluorescence spectroscopy is used to monitor redox and structural changes upon the polarization of the studied memristor with the external electric field. Density functional theory calculations are used to better understand the electronic structure of the studied material, as well as structural rearrangement after electron injection that may be responsible for the modulation of electric conductivity. …”
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Short-chain fatty acids (SCFAs) in gut health: Implications for drug metabolism and therapeutics by P. Sankarganesh, Adrija Bhunia, A. Ganesh Kumar, A. Surendra Babu, S.T. Gopukumar, E. Lokesh

“…The present review aims to elucidate the nutrigenomics and nitrogenic analysis to improve SCFAs to modulate intestinal barrier function, regulate immune responses, and influence host metabolism. …”
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