Altered Pain Perception in a Young Adult with Childhood Trauma and Suspected Riley-Day Syndrome: A Case Report by Pedro Martínez-Lozano, Maurcio Sousa-Pitti, Natalia Toro-Pérez, Juan Nicolás Cuenca-Zaldívar, Rosana Cid-Verdejo, Oliver Martínez-Pozas, Laura Jiménez-Ortega, Eleuterio A. Sánchez-Romero

“…The Central Sensitization Inventory (CSI) and the Symptom Severity Scale (SS) further supported the presence of psychological symptoms suggestive of possible central sensitization. Outcome: Functional improvement was observed after a reduction in substance use and implementation of self-directed physical and cognitive rehabilitation. …”
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Mesenchymal stem cells and their extracellular vesicles: new therapies for cartilage repair by Hongwei Yang, Hongwei Yang, Haochen Yang, Qin Wang, Hanzhen Ji, Tianmei Qian, Tianmei Qian, Yusen Qiao, Junfeng Shi, Meng Cong

“…Cartilage is crucial for joints, and its damage can lead to pain and functional impairment, causing financial burden to patients. …”
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SP-IGAN: An Improved GAN Framework for Effective Utilization of Semantic Priors in Real-World Image Super-Resolution by Meng Wang, Zhengnan Li, Haipeng Liu, Zhaoyu Chen, Kewei Cai

“…Additionally, a wavelet loss is incorporated into the loss function to capture high-frequency details that are often overlooked. …”
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AFMF: adaptive fusion of multi-hop neighborhood features in graph convolutional network by Kang Liu, Xinyu Li, Lian Liu, Zhihao Xv, Aohang Pei, Runshi Ji

“…The cross entropy loss function drives the network to preserve critical information. …”
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Bilateral enhancement network with signal-to-noise ratio fusion for lightweight generalizable low-light image enhancement by Junfeng Wang, Shenghui Huang, Zhanqiang Huo, Shan Zhao, Yingxu Qiao

“…To improve the network’s generalization ability, we propose a Luminance Normalization (LNM) module for preprocessing and a Dual-Exposure Processing (DEP) module for post-processing. …”
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SDDGRNets: Level–Level Semantically Decomposed Dynamic Graph Reasoning Network for Remote Sensing Semantic Change Detection by Zhuli Xie, Gang Wan, Yunxia Yin, Guangde Sun, Dongdong Bu

“…The weighted loss function supervises and optimizes each module separately to enable the network to acquire the optimal feature representation. …”
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Neuropilin-1: a checkpoint target with unique implications for cancer immunology and immunotherapy by Chang Liu, Creg J Workman, Dario AA Vignali, Christopher A Chuckran, Tullia C Bruno

“…In this context, the immunoregulatory receptor Neuropilin-1 (NRP1) is garnering renewed attention as it reinforces intratumoral Treg cell function amidst inflammation in the TME. Loss of NRP1 on Treg cells in mouse models restores antitumor immunity without sacrificing peripheral tolerance. …”
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Impact of immobilization system angle, body mass index and breast size on breast radiotherapy accuracy using EPID-only setup by Ioana-Claudia Costin, Loredana G. Marcu

“…A cohort of 40 breast cancer patients was split into two groups as a function of immobilization board inclination: 20 patients immobilized on 7.5° inclination (group A) and 20 on 0° (group B). …”
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Lightweight SCD-YOLOv5s: The Detection of Small Defects on Passion Fruit with Improved YOLOv5s by Yu Zhou, Zhenye Li, Sheng Xue, Min Wu, Tingting Zhu, Chao Ni

“…Key improvements are introduced as follows: the original C3 module in the backbone is replaced by the enhanced StarC3SE module to achieve a more efficient network structure; the CBAM module is integrated into the neck to improve the extraction of small defect features; and the CIoU loss function is substituted with DIoU-NMS to accelerate convergence and enhance detection accuracy. …”
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UCN-YOLOv5: Traffic Sign Object Detection Algorithm Based on Deep Learning by Peilin Liu, Zhaoyang Xie, Taijun Li

“…Then, ConvNeXt-V2 is integrated, and the C3 module of its Block and YOLOv5 network is used to construct the C3_CN2 structure. …”
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Beyond the Limit: MYC Mediates Tumor Immune Escape by Zhongyang Hong, Sitong Ming, Xin Luan, Zhe Sun, Weidong Zhang

“…Furthermore, we suggest that targeting proteins interacting with MYC to modulate its expression and function may serve as an alternative strategy to direct MYC targeting, thereby expediting the clinical translation of combination therapies.…”
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YOLO-RDM: Innovative Detection Methods for Eggplants and Stems in Complex Natural Environment by Qin Liu, Zhibin Zhou, Lu Xiong, Meilian Lu, Jingwen Ouyang

“…Finally, the loss function is substituted with the MPDIoU loss, optimizing the bounding box regression algorithm and enhancing convergence speed and regression accuracy. …”
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An ESG-ConvNeXt network for steel surface defect classification based on hybrid attention mechanism by Ning Zhang, Ziyang Liu, Enxu Zhang, Yuanqi Chen, Jie Yue

“…Finally, in the downsampling stage, we incorporate a PReLU activation function to mitigate the problem of neuron death during downsampling. …”
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Sonar-based object detection for autonomous underwater vehicles in marine environments by Zhen Wang, Zhen Wang, Jianxin Guo, Shanwen Zhang, Yucheng Zhang

“…Additionally, the CIoU-DFL loss optimization function was constructed to address the class imbalance in sonar data and reduce model computational complexity. …”
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Toward Efficient UAV-Based Small Object Detection: A Lightweight Network with Enhanced Feature Fusion by Xingyu Di, Kangning Cui, Rui-Feng Wang

“…Firstly, a double separation convolution (DSC) module is designed to replace the Bottleneck structure in the C2f module with deep separable convolution and point-by-point convolution fusion, which can reduce the model parameters and calculation complexity while enhancing feature expression. …”
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Intercropping and Nitrogen Fertilization Altered the Patterns of Leaf Senescence in Sorghum by Peter E. Moi, Onesmus M. Kitonyo, George N. Chemining’wa, Josiah M. Kinama

“…Leaf senescence regulates grain yield. However, the modulation of leaf senescence in sorghum under legume-based intercrop systems and nitrogen (N) fertilization is not known. …”
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Xanthohumol: Anti-Inflammatory Effects in Mechanically Stimulated Periodontal Ligament Stem Cells by Christian Niederau, René H. Tolba, Joachim Jankowski, Nikolaus Marx, Michael Wolf, Rogerio Bastos Craveiro

“…This study investigated the anti-inflammatory properties of XN in an in vitro model of compressively stimulated human periodontal ligament stem cells (hPDLSCs), which have a different function in the periodontium than the previously used cementoblasts. …”
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Research Progress on Epigenetic Regulation of Fungal Secondary Metabolism by Siyi TAN, Guanxian CHEN, Lei HE, Qingqing ZHI

“…Beyond its chromatin-modifying function, LaeA also cooperates with other transcription factors such as BrlA and CreA to coordinate complex metabolic networks. …”
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Reprogramming lymphatic endothelial glucose metabolism for the treatment of lymphangiogenesis-related disease by Ziran Zhang, Fan Ye, Huiying Zhang, Xiumiao Li, Wan Mu, Keran Li, Biao Yan

“…Mechanistically, miR-484 directly targeted hexokinase 2 (HK2), a central enzyme in glycolysis, thereby modulating glucose metabolism and mitochondrial function to restrain lymphangiogenesis. …”
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Natural Formulations: Novel Viewpoint for Scleroderma Adjunct Treatment by Shirin Assar, Hosna Khazaei, Maryam Naseri, Fardous El-Senduny, Saeideh Momtaz, Mohammad Hosein Farzaei, Javier Echeverría

“…Natural products can modulate the inflammatory and/or oxidative mediators, regulate the production or function of the immune cells, and control the collagen synthesis, thereby attenuating the experimental and clinical manifestation of the disease. …”
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