Tools for regulating metabolic diseases: extracellular vesicles from adipose macrophages by Liang Zhang, Kecheng Lou, Yunmeng Zhang, Yuanjing Leng, Yuqing Huang, Xinxin Liao, Xiaoliang Liu, Shangzhi Feng, Guoqiang Feng

“…This regulation is likely related to the role of these extracellular vesicles as important mediators in modulating adipose tissue function and insulin sensitivity, and their involvement in the crosstalk between adipocytes and macrophages. …”
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AR and YAP crosstalk: impacts on therapeutic strategies in prostate cancer by Guansong Zheng, Zhaojie Yan, Junrong Zou, Junrong Zou, Junrong Zou, Xiaofeng Zou, Keqiang Chai, Guoxi Zhang

“…AR regulates the stability and function of YAP by modulating its transcription, translation, and phosphorylation status, while YAP exerts both promotional and inhibitory regulatory effects on AR. …”
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Bacteroides fragilis 839 ameliorates anti-tuberculosis drugs-induced liver injury by suppressing inflammation and regulating gut microbiota in mice by Qiujuan Li, Chenbing Wu, Kangshuai Zhang, Ziyi Zhou, Jing Li, Jie Bai, Jun Cao, Xiaoxia Shi

“…These effects were associated with restored gut microbiota diversity, enhanced intestinal barrier function, and reduced inflammatory responses. Our findings suggest that BF839 may serve as a potential preventive strategy for ATB-DILI.…”
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Tunable Circular Dichroism Based on Graphene-Au Chiral Metasurface Structure by Gongli Xiao, Sitong Zhou, Hongyan Yang, Bing Wang, Haiou Li

“…In addition, the periodic cell structure based on this metasurface can realize the digital imaging function and the dynamic modulation of the imaging state can be achieved by adjusting the Fermi energy level, which has potential applications in fields like communication encryption.…”
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Curcumin exerts neuroprotective effects on proliferation of neural stem cells in vitro and APP/PS1 mouse model in vivo by Juanli Chen, Chuanfei Wei, Yingchao Zhang, Qingfa Chen, Xuemei Li, Wei Zhang, Xiaoping Zhang, Fabin Han

“…Additionally, in the APP/PS1 transgenic mouse model, curcumin improved cognitive function, as evidenced by a shorter escape latency and increased platform crossing frequency in the Morris water maze test and enhanced novel object recognition. …”
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Arylsulfatase K attenuates airway epithelial cell senescence in COPD by regulating parkin-mediated mitophagy by Ruonan Yang, Yuan Zhan, Zhesong Deng, Jiaheng Zhang, Shanshan Chen, Yating Zhang, Hao Fu, Xiangling Meng, Jixing Wu, Yiya Gu, Qian Huang, Congyi Wang, Jungang Xie

“…ARSK overexpression alleviated CS-induced epithelial cellular senescence and improved mitophagy and mitochondrial function, while ARSK knockdown had an opposite effect. …”
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MiR-3613-5p targets AQP4 to promote the progression of chronic atrophic gastritis to gastric cancer by Jian Bi, Yufen Wang, Yingde Wang

“…Murine CAG models were established through administration of N-methyl-N-nitrosourea (MNU) and high-salt diet (HSD). In vitro functional assays evaluated proliferation and migration after miRNA modulation in gastric cancer cell lines. …”
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A Novel Detection-and-Replacement-Based Order-Operator for Differential Evolution in Solving Complex Bound Constrained Optimization Problems by Sichen Tao, Sicheng Liu, Shoya Ohta, Ruihan Zhao, Zheng Tang, Yifei Yang

“…This paper systematically reviews the functional differences between mechanism improvements and operator improvements in terms of exploration and exploitation capabilities, based on the general patterns of algorithm enhancements. …”
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Kohonen’s algorithm in problems of classification of defects in printed circuit assemblies by S. U. Uvaysov, V. V. Chernoverskaya, An Kuan Dao, Van Tuan Nguyen

“…The structure of the method is shown, and the composition of the functional blocks is determined. The implementation of the method is a symbiosis of technologies for mathematical and simulation modeling of the technical state of a radio-electronic device with its physical tests and research of characteristics. …”
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Wolbachia elevates host methyltransferase expression and alters the m6A methylation landscape in Aedes aegypti mosquito cells by Michael Leitner, Valentine Murigneux, Kayvan Etebari, Sassan Asgari

“…Gene Ontology analysis revealed that genes with reduced m6A levels were over-represented in functional GO terms associated with purine nucleotide binding functions critical in the post-transcriptional modification process of m6A. …”
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Expression divergence of BAG gene family in maize under heat stress by Babar Farid, Muhammad Abu Bakar Saddique, Muhammad Hammad Nadeem Tahir, Rao Muhammad Ikram, Zulfiqar Ali, Waseem Akbar

“…Once the plant is under heat stress, the BAG genes act as co-chaperones and modulate the molecular functions of HSP70/HSC70 saving the plant from the damage of high temperature stress. …”
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Genomic identification, evolutionary analysis, and transcript profiling of protein phosphatase 2C in Solanum lycopersicum by Miah Mohammad Sakib, Md. Sifatul Islam, Asifur Rob Bhuya, Md. Rihan Kabir Shuvo, Mohammad Abdullah-Al-Shoeb, Muhammad Abul Kalam Azad, Ajit Ghosh

“…This dephosphorylation process is essential for controlling and modulating various cellular functions, including signal transduction, cell cycle progression, metabolic regulation, and stress responses. …”
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Endothelial HSPA12B regulates myocardial monocyte infiltration and inflammatory activity after myocardial infarction by Yana Wang, Min Fan, Min Fan, Linjian Chen, Patrick Spencer Gill, Xiaohui Wang, Xiaohui Wang, Tuanzhu Ha, Tuanzhu Ha, David L. Williams, David L. Williams, Chuanfu Li, Chuanfu Li, Kun Yang, Kun Yang

“…This study investigates whether eHSPA12B regulates monocyte infiltration following MI injury.MethodsWe used endothelial cell-specific Hspa12b knockout (eHspa12b-/-) and wild-type (WT) mice to assess cardiac function and monocyte infiltration following MI. Cardiac resident macrophages and infiltrating monocytes were examined by flow cytometry 3 days post-MI. …”
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Image restoration for ring-array photoacoustic tomography based on an attention mechanism driven conditional generative adversarial network by Wende Dong, Yanli Zhang, Luqi Hu, Songde Liu, Chao Tian

“…Additionally, we have developed a comprehensive loss function to balance pixel-level accuracy, detail preservation, and perceptual quality. …”
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Exploring the role of Transcranial magnetic stimulation in cognitive impairment and sarcopenia: a narrative review by Yuhong Wang, Weichao Li, Tingting Dong, Rui Xu, Qing Ai, Lili Yang, Xuesong Gai, Li Li

“…Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation technique that can modulate neural plasticity and reduce inflammation and oxidative stress, demonstrating considerable potential for improving CI and motor function disorders. …”
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Role of ginger in fish nutrition with special emphasis on growth, health, gut and liver morphology by Ishtiyaq Ahmad, Misbah Irm, Imtiaz Ahmed, Yin Haoran, Sehrish Taj, Tahir Ahmad Bhat, Saba Khursheed Khan, Sabah Mushtaq Puswal, Hala Saber Khalil, Mentor Sopjani, Helena Peres, Caterina Faggio, Mohd Ashraf Rather, Adnan Amin

“…They have shown several benefits, acting as growth promoters and modulators of physiological and biochemical functions. …”
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THE ROLE OF MECHANICAL PROPERTIES OF T-CELLS IN SHAPING THE IMMUNE RESPONSE by Grigory Gorshkov, Anatoliy Bykov, Oxana Svitich

“…It has been demonstrated that microenvironment stiffness, mechanical interactions with the extracellular matrix, and changes in membrane tension can modulate T-cell activation, migration, proliferation, and effector functions. …”
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The protective effect of Gentiana lutea flower against mycotoxin toxicity in a gastrointestinal barrier in vitro model by Giacomo Di Matteo, Giacomo Di Matteo, Giacomo Di Matteo, Massimo Frangiamone, Pilar Vila-Donat, Valter Di Cecco, Luciano Di Martino, Lara Manyes, Luisa Mannina, Luisa Mannina, Luisa Mannina

“…The digested Gentiana samples reduced the expression of pro-apoptotic genes (BAX, CASP3), preserved intestinal barrier integrity by modulating tight junction-related genes (CL-2, ZO-1), and promoted antioxidant responses through SRXN1 regulation.ConclusionThese findings highlight the potential of Gentiana lutea flowers as a source of functional phytocompounds for intestinal barrier protection against mycotoxins.…”
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Enhancement of in vitro digestive properties of silver carp (Hypophthalmichthys olivaceus) surimi gels by oxidized dihydromyricetin by Qianhui Yu, Jinlin Li, Qinye Yu, Yongjie Zhou, Yuqing Tan, Yongkang Luo, Hui Hong

“…Improving the digestibility of surimi products is key to boosting both their nutritional value and functional benefits. This study investigated how oxidized dihydromyricetin (oDMY) influences the digestion of silver carp surimi. …”
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Identification and characterization of the GH3 gene family in maize by Dong-feng ZHANG, Nan ZHANG, Tao ZHONG, Chao WANG, Ming-liang XU, Jian-rong YE

“…Results presented here provide insight into the diversification and evolution of GH3 proteins, and lay a foundation for the functional characterization of these GH3 genes in future, especially for elucidating the mechanisms of GH3-mediated pathogenesis.…”
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