Multifocal Electroretinography as a Method of Functional Assessment of Retinal Laser Injury in Experimental Studies by A. A. Suetov, S. I. Alekperov, M. A. Odinokaya, A. A. Kostina, E. A. Petrova

“…Purpose: to investigate local functional changes in the rabbit retina by multifocal electroretinography under pulsed laser radiation.Materials and methods. …”
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Lateralization of memory function in temporal lobe epilepsy using scene memory fMRI by William S. Tackett, Dawn Mechanic‐Hamilton, Sandhitsu Das, Marissa Mojena, Joel M. Stein, Kathryn A. Davis, John A. Detre

“…However, fMRI lateralization of episodic memory remains challenging because the hippocampus, which is fundamental to episodic memory, is smaller, more prone to susceptibility artifact, and harder to functionally modulate than language regions. We previously showed that a complex scene memory task can lateralize memory function in the mesial temporal lobe. …”
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Landscape of mobile genetic elements and their functional cargo across the gastrointestinal tract microbiomes in ruminants by Yijun Tang, Pengchao Zhan, Yingjian Wu, Tao Zhang, Di Yin, Yunlong Gao, Yueying Yu, Shengnan Qiu, Jiaqi Zhao, Xue Zhang, Zhe Ma, Yanting Chen, Liang Zhao, Shengyong Mao, Jinhu Huang, Wei-Hua Chen, Jinxin Liu

“…Conclusions This study substantially expands the catalog of known MGEs in ruminants, revealing their diverse roles in microbial evolution and functional adaptation to dietary changes. The findings provide a valuable resource for advancing research on microbial functionality and offer insights with potential applications for enhancing ruminant health and productivity, through strategies aimed at modulating the microbiome in agricultural contexts. …”
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Thiazolopyridines Improve Adipocyte Function by Inhibiting 11 Beta-HSD1 Oxoreductase Activity by Thirumurugan Rathinasabapathy, Kimberly Marie Palatini Jackson, Yiwen Thor, Ayuba Sunday Buru, Debora Esposito, Xu Li, Mallikarjuna Rao Pichika, Ahmad Sazali Hamzah, Slavko Komarnytsky

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Type I collagen secreted in white matter lesions inhibits remyelination and functional recovery by Reiji Yamazaki, Morio Azuma, Yasuyuki Osanai, Tom Kouki, Takeshi Inagaki, Akiyoshi Kakita, Masaki Takao, Nobuhiko Ohno

“…In the current study, we demonstrated that collagen fibres accumulated in the demyelinated lesions of multiple sclerosis patients (age range 23–80 years) and white matter lesions of stroke patients (age range 80–87 years), suggesting that the accumulation of collagen fibres correlates with remyelination failure in these lesions. To investigate the function of collagen fibres in the white matter lesions, we generated two types of white matter injury in mice. …”
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Community differences and potential function along the particle size spectrum of microbes in the twilight zone by Yue Zhang, Hongbin Liu, Hongmei Jing

“…Conclusion Our study reveals significant shifts in microbial community composition and function in the twilight zone, with clear differences among the three particle sizes. …”
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Rheumatoid Arthritis and miRNAs: A Critical Review through a Functional View by Maria Cristina Moran-Moguel, Stefania Petarra-del Rio, Evangelina E. Mayorquin-Galvan, Maria G. Zavala-Cerna

“…Nevertheless, miRNAs seem to be important regulators of networks instead of single genes; their hypothetical use as biomarkers needs to rely on a functional integrative description of their effects in the biological process of autoimmune conditions which until now is missing. …”
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Selenium Alleviates Low-Temperature Stress in Rice by Regulating Metabolic Networks and Functional Genes by Naixin Liu, Qingtao Yu, Baicui Chen, Chengxin Li, Fanshan Bu, Jingrui Li, Xianlong Peng, Yuncai Lu

“…In contrast, high selenium concentrations (ColdSe2) disrupted phenylpropanoid biosynthesis, α-linolenic acid metabolism, and ABC transporter function, exacerbating cold-stress injury. This study highlights the critical role of Se in mitigating cold stress in rice, offering a theoretical basis for its application as an agricultural stress reliever.…”
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Inhibition of Sirtuin 2 enhances autophagy and restores neuronal function in aged hippocampal neurons by Zhenyuan Zhang, Lan Zhang, Yidan Zhang, Yuan Zhao, Ya Gao, Cong Zhang, Dongxiao Li, Xiangjian Zhang, Guofeng Yang, Jian Zhang

“…This study investigates the role of Sirtuin 2 (SIRT2) in age-related cognitive decline, focusing on its impact on autophagy and hippocampal function. Quantitative proteomic analysis revealed 67 significantly dysregulated proteins in the hippocampus of naturally aged male mice, including upregulated SIRT2 and impaired autophagy. …”
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Cerium oxide nanoparticles in vivo distribution and transformation behavior mediate intestinal transit function by Chunli Lei, Rui Liang, Bingxu Cheng, Le Yue, Xuesong Cao, Chuanxi Wang, Zhenyu Wang, Baoshan Xing

“…Therefore, this work provides more accurate descriptions of the entire physiological process of CeO2 NPs after ingestion, spotlights their intestinal transport fate and redox functional effects, and opens up new theoretical perspectives for potential human health studies of NPs.…”
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First-Principles Study on Interfacial Triboelectrification Between Water and Halogen-Functionalized Polymer Surfaces by Taili Tian, Bo Zhao, Yimin Wang, Shifan Huang, Xiangcheng Ju, Yuyan Fan

“…The results reveal that electron transfer is primarily governed by the energy levels of the polymer’s lowest unoccupied molecular orbital (LUMO) and highest occupied molecular orbital (HOMO). Halogen functional groups modulate the material’s electron-donating/accepting capabilities by altering these frontier orbital energy levels. …”
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Epigenetic Alterations in Ovarian Function and Their Impact on Assisted Reproductive Technologies: A Systematic Review by Charalampos Voros, Antonia Varthaliti, Despoina Mavrogianni, Diamantis Athanasiou, Antonia Athanasiou, Aikaterini Athanasiou, Anthi-Maria Papahliou, Constantinos G. Zografos, Vasileios Topalis, Panagiota Kondili, Menelaos Darlas, Sophia Sina, Maria Anastasia Daskalaki, Marianna Theodora, Panos Antsaklis, Georgios Daskalakis

“…<b>Background</b>: Epigenetic modifications have an important role in controlling ovarian function, modulating ovarian response and implantation success in Assisted Reproductive Technologies (ART). …”
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Bio-functional hydrogel coated membranes to decrease T-cell exhaustion in manufacturing of CAR T-cells by Aida López Ruiz, Eric Slaughter, Kartik Bomb, Samantha L. Swedzinski, Paige J. LeValley, Zaining Yun, Jacob McCoskey, Kara Levine, Jonathan Steen, Joseph Almasian, Aparajita Chatterjee, Christina Carbrello, Dustin S. Chang, Hubaida Fuseini, Yama A. Abassi, Abraham M. Lenhoff, Catherine A. Fromen, April M. Kloxin, April M. Kloxin

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Klebsiella pneumoniae-derived extracellular vesicles impair endothelial function by inhibiting SIRT1 by Xinxin Li, Jinghua Cui, Zanbo Ding, Ziyan Tian, Yiming Kong, Linghai Li, Yang Liu, Wen Zhao, Xueying Chen, Han Guo, Zhengshuo Cui, Xinwei Li, Jing Yuan, Huina Zhang

“…Bacterial extracellular vesicles (BEVs) released by Gram-negative bacteria modulate host cell functions by delivering bacterial components to host cells. …”
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Osteopontin protects from ovalbumin-induced asthma by preserving the microbiome and the intestinal barrier function by Jinli Huang, Hongyu Qiao, Qiuhong Li, Yi Zhang, Chenyu Zhang, Hui Su, Xin Sun

“…The present study suggests that OPN may moderate OVA-induced asthma by modulating the gut and lung microbiota.IMPORTANCEOsteopontin deficiency exacerbated asthmatic airway inflammation, an effect associated with microbiota dysbiosis, impaired intestinal barrier function, and increased PD-1/PD-L1 expression and thus decreased Treg cell function. …”
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Altered Brain Functional Connectivity and Neurometabolite Correlations in Orofacial Chronic Pain with Central Sensitization by Terumitsu M, Takado Y, Fukuda KI, Kato E, Tanaka S, Tha KK

“…Chronic pain reportedly alters resting-state functional connectivity (FC) in the brain. The salience network (SN) overlaps with brain regions involved in chronic pain. …”
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The contrasted impacts of grasshoppers on soil microbial activities in function of primary production and herbivore diet by Ibanez, Sébastien, Foulquier, Arnaud, Brun, Charles, Colace, Marie-Pascale, Piton, Gabin, Bernard, Lionel, Gallet, Christiane, Clément, Jean-Christophe

“…This highlights the multidimensional feature of the impacts of herbivory on ecosystem functioning, both in space and time. …”
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Apocynin and Hyperbaric Oxygen Therapy Improve Renal Function and Structure in an Animal Model of CKD by Andrija Vukovic, Danijela Karanovic, Nevena D Mihailovic-Stanojevic, Zoran Miloradovic, Predrag Brkic, Maja Zivotic, Jelena Nesovic Ostojic, Milan Ivanov, Sanjin Kovacevic, Una-Jovana Vajic, Djurdjica Jovovic, Silvio R. De Luka

“…Combined treatment (apocynin and HBOT) normalized blood pressure (BP) values, renal function, and improved kidney structure by modulating FN and HIF-1α, without affecting desmin protein expression. …”
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Structural and functional investigation of DinG containing a 3′–5′ exonuclease domain by Tianwen Gao, Wanshan Hao, Jin Gao, Yiyang Sun, Yukang Sun, Jieyu Yang, Kaiying Cheng

“…Our findings resolve previous uncertainties about SaDinG's function and reveal an ATP-dependent regulatory mechanism that modulates its activity. …”
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Design of Eye Models for Quantitative Analysis of Interactions Between Ocular Aberrations and Intraocular Scattering by Feng Rao, Lin Zhang, Xinheng Zhao, Jing Li, Jie Hou, Yan Wang

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