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9561
Recent advancements and comprehensive analyses of butyric acid in cardiovascular diseases
Published 2025-07-01“…Butyrate is instrumental in maintaining intestinal barrier function and immune homeostasis and exhibits notable anti-inflammatory, antioxidant, and metabolic regulatory potentials in cardiovascular diseases. …”
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9562
Intercellular adhesion disorders in tumorigenesis
Published 2024-09-01“…Direct communication between brain DA and peripheral DA is crucial in modulating immune function. Peripheral DA mediates differentiation, binding to tumor cells, and cytotoxicity of CD8+ T cells. …”
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9563
The what and where of adding channel noise to the Hodgkin-Huxley equations.
Published 2011-11-01“…As such, we hope that this review will speed emerging studies of how channel noise modulates electrophysiological dynamics and function. …”
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9564
Evaluating the role of trimetazidine in preventing myocardial injury and contrast-induced nephropathy in patients undergoing percutaneous coronary interventions
Published 2025-05-01“…Trimetazidine (TMZ), a metabolic modulator with cardioprotective and renal protective properties, may reduce these risks. …”
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9565
Submarine Cable Vibration Signal Recognition Based on Sparrow Search Algorithm Optimized Support Vector Machine
Published 2023-10-01“…Then, the SSA was used to optimize the penalty factor and kernel function parameters of the SVM, thereby improving the recognition accuracy. …”
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9566
Stenotrophomonas maltophilia virulence and specific variations in trace elements during acute lung infection: implications in cystic fibrosis.
Published 2014-01-01“…Overall, our data clearly indicate that S. maltophilia modulates pulmonary metal balance in a concerted and virulence-dependent manner highlighting the potential role of the element dyshomeostasis during the progression of S. maltophilia infection, probably exacerbating the harmful effects of the loss of CF transmembrane conductance regulator function. …”
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9567
Tryptophan and Its Metabolite Serotonin Impact Metabolic and Mental Disorders via the Brain–Gut–Microbiome Axis: A Focus on Sex Differences
Published 2025-03-01“…Emerging evidence suggests that the gut microbiome regulates brain function and behavior, particularly through microbial influences on tryptophan metabolism and the serotonergic system, both of which are essential for normal functioning. …”
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9568
Lane-Keeping Assistance System Based on Model Predictive Control With Smooth Transitions Between Operational Modes
Published 2025-01-01“…The lane-keeping assistance system (LKAS) is one of the core functions of advanced driver assistance systems (ADAS) that prevents unintended lane departures. …”
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9569
Visualizing sound emission of elephant vocalizations: evidence for two rumble production types.
Published 2012-01-01“…These results suggest that African elephants may be switching vocal paths to actively vary vocal tract length (with considerable variation in formants) according to context, and call for further research investigating the function of formant modulation in elephant vocalizations. …”
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9570
A Dominant-Negative PPARγ Mutant Promotes Cell Cycle Progression and Cell Growth in Vascular Smooth Muscle Cells
Published 2009-01-01“…We herein report that a synthetic dominant-negative (DN) PPARγ mutant functions like a growth factor to promote cell cycle progression and cell proliferation in human coronary artery smooth muscle cells (CASMCs). …”
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9571
Human Gut Bacteriophageome: Insights Into Drug Resistance Mechanisms in Tuberculosis
Published 2025-01-01“…The gut phageome plays a crucial role in regulating microbial diversity and functionality, and its composition and function have been linked to various health conditions. …”
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9572
Intestinal microflora shaping factors: emphasis on lipids
Published 2023-02-01“…The totality of microorganisms closely interacting with each other and with human cells is currently considered as another organ in the human body and is called the «microbiota». The functions of the intestinal microbiota are very diverse: anti-infective protection, modulation of the inflammatory and immune response, synthesis of compounds necessary for the body (for example, vitamins, shortchain fatty acids), participation in the digestion of a number of nutrients, as well as the regulation of intestinal motility, proliferation and differentiation of intestinal epithelial cells. …”
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9573
Application of Machine Learning Methods for Identifying Wave Aberrations from Combined Intensity Patterns Generated Using a Multi-Order Diffractive Spatial Filter
Published 2025-05-01“…A multi-order combined diffraction spatial filter, integrated with a set of Zernike phase functions (representing wavefront aberrations) and Zernike polynomials, enables the simultaneous formation of multiple aberration-transformed point spread function (PSF) patterns in a single plane. …”
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9574
STAT signaling pathways in immune cells and their associated mechanisms in cancer pathogenesis
Published 2024-05-01“…Increase of knowledge about these pathways’ functions is essential to understand how they can be effectively targeted to eliminate tumors. …”
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9575
Δ133p53α and Δ160p53α isoforms of the tumor suppressor protein p53 exert dominant-negative effect primarily by co-aggregation
Published 2025-07-01“…p53 is a tumor suppressor protein with multiple isoforms with shared or specific functions. However, two of its isoforms, Δ133p53α and Δ160p53α, with large N-terminal deletions, can cause cancer. …”
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9576
Chi-miR-4110 promotes granulosa cell apoptosis by targeting Sma- and Mad-related protein 2 (Smad2) in the caprine ovary.
Published 2017-01-01“…Whilst our previous investigations examined the role of chi-miR-4110 in regulating ovarian function, the present study detected the role of chi-miR-4110 in GC development. …”
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9577
Caspase 3 and caspase 7 promote cytoprotective autophagy and the DNA damage response during non-lethal stress conditions in human breast cancer cells.
Published 2025-02-01“…We found a functionally conserved role for effector caspase 3 (CASP3) and caspase 7 (CASP7) in promoting starvation or proteasome inhibition-induced cytoprotective autophagy in human breast cancer cells. …”
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9578
Chitosan-MXene-gold-curcumin: quaternary nanohybrid platform: A Chemo/Photothermal onco-strategy for improved cancer therapy
Published 2025-06-01“…Moreover, the encapsulated polyphenolic curcumin played a crucial role in modulating p53 and VEGF levels, while also demonstrating strong free radical scavenging activity.Nanotoxicity assessment, based on liver and kidney function, yielded satisfactory results, confirming the safety of the nanoparticles. …”
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9579
The gene regulatory cascade linking proneural specification with differentiation in Drosophila sensory neurons.
Published 2011-01-01“…In addition, it provides a paradigm for how transcriptional regulation may modulate the ciliogenesis pathway to give rise to structurally and functionally specialised ciliary dendrites.…”
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9580
Mitigating Selection Bias in Recommendation Systems Through Sentiment Analysis and Dynamic Debiasing
Published 2025-04-01“…Additionally, we have designed a combinatorial function that adapts to three distinct scenarios for bias correction. …”
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