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9441
The Effect of Sleep Disruption on Cardiometabolic Health
Published 2025-01-01“…The latest evidence points to the role of sleep-induced changes in the composition and function of gut microbiota, which may contribute to metabolic dysfunction through modifications in the intestinal barrier and inflammatory responses. …”
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9442
PROSPECTS FOR ANTI-B-CELL THERAPY IN IMMUNO-INFLAMMATORY RHEUMATIC DISEASES
Published 2019-12-01“…Its efficiency is determined by various mechanisms, such as suppression of pathogenic autoantibody synthesis; modulation of the function of B-cells (antigen presentation, cytokine synthesis, and costimulation), T-lymphocytes and dendritic cells. …”
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9443
Honeycomb lung segmentation network based on P2T with CNN two-branch parallelism
Published 2024-12-01“…To resolve the problem of model accuracy degradation caused by the class imbalance of the dataset, an adaptive weighted hybrid loss function is designed for model training. Finally, extensive experimental results show that the method in this paper performs well on the Honeycomb Lung Dataset, with Intersection over Union (IoU), mean Intersection over Union (mIoU), Dice coefficient, and Precision (Pre) of 0.8750, 0.9363, 0.9298, and 0.9012, respectively, which are better than other methods. …”
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9444
A Lightweight Barcode Detection Algorithm Based on Deep Learning
Published 2024-11-01“…Finally, the reconstruction of the model’s detection head and the modification of the loss function are implemented to enhance the model’s training quality and reduce the model’s error in barcode detection. …”
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9445
Pitfalls of space-time trading when parametrizing a land use dependent hydrological model
Published 2022-09-01“…Evaporation is a function of both climate conditions and other environmental conditions, including land use. …”
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9446
EFNet: estimation of left ventricular ejection fraction from cardiac ultrasound videos using deep learning
Published 2025-01-01“…The ejection fraction (EF) is a vital metric for assessing cardiovascular function through cardiac ultrasound. Manual evaluation is time-consuming and exhibits high variability among observers. …”
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9447
Semi‐supervised contextual cognitive augmentation‐based cross‐teaching network for multiclass medical image segmentation
Published 2024-11-01“…Additionally, a cross‐teaching strategy is adopted and a hybrid loss function is utilized to encourage knowledge sharing among the networks, leveraging the advantages of dual networks for improved performance. …”
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9448
PPARG: Gene Expression Regulation and Next-Generation Sequencing for Unsolved Issues
Published 2010-01-01“…It is of particular interest because of its pleiotropic functions: it plays a crucial role in the expression of key genes involved in adipogenesis, lipid and glucid metabolism, atherosclerosis, inflammation, and cancer. …”
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9449
Expression of NKp46 and other activating inhibitory receptors on uterine endometrial NK cells in females with various reproductive failures: A review
Published 2025-01-01“…However, immunotherapies focusing on modulating uNK cell function have been controversial in terms of pregnancy outcomes. …”
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9450
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9451
Emerging Targets in Pituitary Adenomas: Role of the CXCL12/CXCR4-R7 System
Published 2014-01-01“…Importantly, the multiple intracellular signalling generated by CXCL12 interaction with its receptors influences hypothalamic modulation of neuroendocrine functions, although a direct modulation of pituitary functioning via autocrine/paracrine mechanisms was also reported. …”
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9452
An algorithm for road target detection of autonomous vehicles based on improved YOLOv8
Published 2025-07-01“…Improve the loss function CIOU of the original model to EIOU to further enhance the detection accuracy of the model for road targets. …”
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9453
Hash-Guided Adaptive Matching and Progressive Multi-Scale Aggregation for Reference-Based Image Super-Resolution
Published 2025-06-01“…In addition, a learnable similarity scoring function has been designed to adaptively optimize the similarity score between LR images and Ref images, improving matching accuracy. …”
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9454
An efficient fire detection algorithm based on Mamba space state linear attention
Published 2025-04-01“…Additionally, a dynamic non-monotonic focusing mechanism and distance penalty strategy are employed to refine the loss function, leading to a substantial improvement in bounding box accuracy. …”
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9455
A Global-Speed-Region Voltage Angle Control Method Considering Dead-Time Effect Compensation for Permanent Magnet Synchronous Motor Drives
Published 2024-12-01“…Firstly, the application area of the proposed method is extended to both the high-speed and low-speed region on the basis of analyzing the variation function of the modulation index (<i>MI</i>), achieving global non-mode-switching control and eliminating the torque jitter. …”
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9456
Understanding Microglia in Mesocorticolimbic Circuits: Implications for the Study of Chronic Stress and Substance Use Disorders
Published 2025-07-01“…Review current methods of interrogating microglial function with a focus on morphometric analyses. 3. …”
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9457
Enter the Matrix: Fibroblast-immune cell interactions shape extracellular matrix deposition in health and disease. [version 2; peer review: 1 approved, 2 approved with reservations...
Published 2024-12-01“…Fibroblasts can directly and indirectly regulate immune responses by secreting ECM and ECM-bound molecules to shape tissue structure and influence organ function. In this review, we will highlight recent studies which elucidate the mechanisms by which fibroblast-derived ECM factors (e.g., collagens, fibrillar proteins) regulate ECM architecture and subsequent immune responses, with a focus on macrophages. …”
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9458
Drought Tolerance in Plants: Physiological and Molecular Responses
Published 2024-10-01“…Osmotic stress, dehydration stress, dysfunction of plasma and endosome membranes, loss of cellular turgidity, inhibition of metabolite synthesis, cellular energy depletion, impaired chloroplast function, and oxidative stress are among the most critical consequences of drought on plant cells. …”
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9459
Exercise mediates myocardial infarction via non-coding RNAs
Published 2024-11-01“…The expression of specific ncRNAs is altered by exercise, leading to beneficial changes in heart structure, function, and recovery after MI. These ncRNAs modulate molecular pathways that contribute to improved cardiac health, including reducing inflammation, enhancing angiogenesis, promoting cell survival, and mitigating oxidative stress. …”
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9460
The neuromechanical delay of the quadriceps shortens with increasing contraction intensity
Published 2025-07-01“…These findings enhance our understanding of neuromechanical coupling, revealing a force-dependent modulation of NMD that may have implications for neuromuscular function in health and disease.…”
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