Spin polarised quantum conductance in 1D channels by Henry Montagu, Ian Farrer, David Ritchie, Sanjeev Kumar

“…The differential conductance shows regular quantised plateaus in units of 2 e ^2 / h as a function of back gate voltage, including the observation of the 0.7(2 e ^2 / h ) conductance anomaly. …”
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MF-YOLOv10: Research on the Improved YOLOv10 Intelligent Identification Algorithm for Goods by Quanwei Wang, Xiaoyang Wang, Jiayi Hou, Xuying Liu, Hao Wen, Ziya Ji

“…The algorithm significantly improves the feature extraction and detection capabilities by replacing the traditional IoU loss function with the MPDIoU and introducing the SCSA attention module. …”
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Inhibition of Toll-Like Receptor 2-Mediated Interleukin-8 Production in Cystic Fibrosis Airway Epithelial Cells via the α7-Nicotinic Acetylcholine Receptor by Catherine M. Greene, Hugh Ramsay, Robert J. Wells, Shane J. O'Neill, Noel G. McElvaney

“…Inflammation in the CF lung is initiated by microbial components which activate the innate immune response via Toll-like receptors (TLRs), increasing airway epithelial cell production of proinflammatory mediators such as the neutrophil chemokine interleukin-8 (IL-8). Thus modulation of TLR function represents a therapeutic approach for CF. …”
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Molecular Diversity and Isoform Evolution in <i>Tityus obscurus</i> Venom: Insights from Proteomic Analysis by Kemellyn Cristina Panchera, Lais Campelo Mendes, Ana Leonor Abrahão Nencioni, Daniel Carvalho Pimenta, Emídio Beraldo-Neto

“…These findings contribute to our understanding of venom molecular diversity and evolution, providing new insights into peptide structure–function relationships. Considering the biomedical relevance of ion channel-modulating toxins, our work expands the repertoire of potential candidates for future drug development, particularly in the context of neuropharmacology and ion channel disorders.…”
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Memory T Cells, Recombinant Listeria monocytogenes, and Cancer Vaccines by Abolaji Samson Olagunju, Maribel Limachi Loza, Marielly Câmara Rocha, Gustavo P. Amarante-Mendes

“…Notably, L. monocytogenes has unique properties that make it an ideal candidate for this purpose: it is highly effective at activating T cells, promoting the differentiation and survival of memory T cells, and modulating the TME to favor immune cell function. Thus, by leveraging the ability of L. monocytogenes to induce a strong, sustained T-cell response, researchers aim to develop vaccines that provide lasting immunity against tumors, reduce recurrence rates, and improve patient survival outcomes. …”
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Tapinarof Nanogels as a Promising Therapeutic Approach by Barbara Balogh, Ágota Pető, Pálma Fehér, Zoltán Ujhelyi, Ildikó Bácskay

“…Furthermore, nanogel formulations can improve skin hydration and support the restoration of skin barrier function, which are important in the treatment of psoriasis. …”
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YAP charge patterning mediates signal integration through transcriptional co-condensates by Kirstin Meyer, Klaus Yserentant, Rasmi Cheloor-Kovilakam, Kiersten M. Ruff, Chan-I Chung, Xiaokun Shu, Bo Huang, Orion D. Weiner

“…Our work reveals a molecular framework for YAP condensate formation and sheds light on the function of YAP condensates for emergent gene regulatory behavior.…”
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Freezing induced incorporation of betaine in lipid nanoparticles enhances mRNA delivery by Xingdi Cheng, Xia Zheng, Kun Tao, Haonan Huo, Zhang Liu, Xueguang Lu, Jianjun Wang

“…These findings highlight freeze concentration as a promising LNP formulation strategy and underscore the role of CPA as active modulators of LNP structure and function.…”
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Targeting glutamine metabolism as a potential target for cancer treatment by Wenxuan Zou, Zitao Han, Zihan Wang, Qian Liu

“…A body of research has demonstrated that the metabolic processes of glutamine regulate a variety of immune system functions, including T cell depletion/activation, the polarization of TAMs, and the function of NK cells. …”
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Retinal vascular segmentation network based on dual-scale morphological enhancement by Yunfeng Ni, Pei Wang, Wei Chen, Jie Qi

“…This study employs a combination of binary cross-entropy and structural similarity loss functions to accurately generate binary segmentation results. …”
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Lactylation’s role in bone health and disease: mechanistic insights and therapeutic potential by Zhiyuan Ye, Xuanyu Chen, Jiyuan Zou, Wenjing Wu, Jingyuan Yang, Li Yang, Lvhua Guo, Tao Luo

“…Studies indicate that lactylation plays a significant role in bone metabolism, with mechanisms including the regulation of osteoblast differentiation, potential influence on osteoclast activity, and indirect effects on bone homeostasis through the modulation of immune cell functions such as macrophages and T cells. …”
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Enhanced neuromorphogenesis of neural stem cells via the optimization of physical stimulus-responsive signaling pathways by Youyi Tai, Natasha Brinkley, Lu Jin, Yu Wei Chang, Allen Liakhovetski, Jin Nam

“…The combination of physical stimulation with biochemical factors to modulate those signaling pathways further enhanced neuromorphogenesis, offering a reliable and robust strategy to develop fully functional neural stem cell-derived in vitro nerve models.…”
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Adaptation of the DFD technology in the modeling of business systems in the environment of RDS by G. N. Kalyanov, B. V. Kupriyanov, O. V. Lukinova

“…The article defines the purpose, composition and structure of the business process simulation module.…”
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Xiao Yao San mitigates corticosterone stimulation-induced hippocampal neuronal damage by inhibiting GR phosphorylation and nuclear translocation via FKBP4 involvement by Xuedi Kang, Ting Wang, Haiping Wan, Wenjun Fu, Songjun Lin

“…The influence of FKBP4 on the competitive binding of GR was explored via similar techniques. The functional consequences of gene knockdown and overexpression were evaluated through cellular assays. …”
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Impression Cytology of Bulbar Conjunctiva in Refractive Patients by A. V. Doga, S. A. Borzenok, I. A. Mushkova, A. N. Karimova, M. R. Obraztsova, M. Kh. Khubetsova, D. S. Ostrovskiy

“…Maintaining a healthy eye surface is very important both for performing high-quality visual work and for maintaining a socially active lifestyle. A stable and functional tear film is necessary to protect and maintain the normal balance of the eye surface.Purpose: to determine the density of goblet cells of the bulbar conjunctiva in refractive profile patients at the pre- and postoperative stages, taking into account the condition of the ocular surface.Patients and methods. …”
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Exploring the Nutraceutical Potential of a Food–Medicine Compound for Metabolic-Associated Fatty Liver Disease via Lipidomics and Network Pharmacology by Yuru Deng, Jie Cui, Yuxuan Jiang, Jian Zhang, Jinchi Jiang, Quanbin Zhang, Yonghong Hu

“…This research underscores the critical role of the FMH complex in modulating lipid metabolism and inflammatory pathways, offering valuable insights for developing FMH-based dietary supplements and functional foods to alleviate MAFLD. …”
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Cross-User Electromyography Pattern Recognition Based on a Novel Spatial-Temporal Graph Convolutional Network by Mengjuan Xu, Xiang Chen, Yuwen Ruan, Xu Zhang

“…The ablation experiments show that each functional module of the proposed CNN-MSTGCN network has played a more or less positive role in improving the performance of EMG pattern recognition. …”
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Synergistic gut microbiome-mediated degradation of Astragalus membranaceus polysaccharides and Codonopsis pilosula polysaccharides into butyric acid: a metatranscriptomic analysis by XinQian Rong, LingFeng Zhu, QingLong Shu

“…This work not only contributes to the field of microbiome research but also supports the development of functional foods and therapeutics aimed at enhancing gut health through targeted polysaccharide consumption.…”
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Neurocomputational Mechanisms of Sense of Agency: Literature Review for Integrating Predictive Coding and Adaptive Control in Human–Machine Interfaces by Anirban Dutta

“…Disruptions in these inference processes underlie symptoms in disorders such as functional movement disorder. XR-based interventions using robotic interfaces can restore the SoA by modulating sensory precision and motor predictions through adaptive feedback and suggestion. …”
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Crotonylation-Related Prognostic Model of Esophageal Squamous Cell Carcinoma Based on Transcriptome Analysis and Single-Cell Sequencing Analysis by Lin RY, Chen RP, Lin FQ

“…Independent prognostic analysis and nomogram construction followed. Functional enrichment and immune infiltration analyses were performed using the prognostic genes. …”
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