Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies. by Narinder Janghra, Jennifer E Morgan, Caroline A Sewry, Francis X Wilson, Kay E Davies, Francesco Muntoni, Jonathon Tinsley

“…Lack of dystrophin leads to loss of muscle fibres and a reduction in muscle mass and function. There is evidence from dystrophin-deficient mouse models that increasing levels of utrophin at the muscle fibre sarcolemma by genetic or pharmacological means significantly reduces the muscular dystrophy pathology. …”
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Akkermansia muciniphila helps in the recovery of lipopolysaccharide-fed mice with mild intestinal dysfunction by Yue Hu, Yue Hu, Jun Zhou, Xiaoqi Lin

“…BackgroundMild intestinal dysfunction, linked to subtle yet significant health issues, can be induced by lipopolysaccharide (LPS), a Gram-negative bacterial component that disrupts gut function and triggers inflammation. Akkermansia muciniphila has shown promise as a probiotic for gut health due to its roles in mucin degradation and short-chain fatty acid production. …”
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Multi-Robot Cooperative Simultaneous Localization and Mapping Algorithm Based on Sub-Graph Partitioning by Wan Xu, Yanliang Chen, Shijie Liu, Ao Nie, Rupeng Chen

“…Second, an improved distributed robust pose graph optimization algorithm is proposed in the back-end module. By introducing a robust cost function to filter out erroneous loop closures and employing a subgraph optimization strategy during iterative optimization, the proposed approach enhances convergence speed and solution quality, thereby reducing uncertainty in multi-robot pose association. …”
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A Novel YOLOv10-Based Algorithm for Accurate Steel Surface Defect Detection by Liefa Liao, Chao Song, Shouluan Wu, Jianglong Fu

“…YOLOv10n-SFDC incorporates advanced elements such as the DualConv module, SlimFusionCSP module, and Shape-IoU loss function, improving feature extraction, fusion, and bounding box regression to enhance accuracy. …”
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Role of Gut Microbiota in the Pathogenesis of Cardiovascular Diseases and Metabolic Syndrome by O. M. Drapkina, O. E. Shirobokikh

“…It is also discussed how modulating of gut microbiota composition and function through diet, prebiotics, probiotics and fecal microbiota transplantation can become a novel therapeutic and preventative target for CVD and metabolic syndrome. …”
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The reverse association between riboflavin intake and Helicobacter pylori infection in US adults: A cross-sectional study. by Xinyu Xu, Peizhong Chen, Yingyi Li, Xiaoxuan Chen, Yunhui Yan, Zicheng Huang

“…<h4>Conclusion</h4>These findings suggest that dietary riboflavin may inversely correlate with H. pylori infection in a dose-responsive manner, potentially mediated through mitochondrial function preservation, oxidative stress reduction, and gut microbiota modulation. …”
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Trimetazidine stimulates intracellular Ca2+ transients and zebrafish locomotor activity in spinal neurons by Sara Bernardi, Sara Vitolo, Chiara Gabellini, Maria Marchese, Elisabetta Ferraro

“…The mechanism underlying the effect of TMZ on locomotor activity has been proposed to rely on its ability to enhance metabolic efficiency with a consequent improvement of myogenesis and of neuromuscular junction (NMJ) and muscle function. However, although promising and therefore under clinical trials, the mechanism of action of TMZ has not been clearly disclosed; here we hypothesized that it might involve the modulation of neuronal Ca2+ flows. …”
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ETC-PCR: Coarse-to-Fine Edge-Triangle Compatibility for Robust and Accurate Point Cloud Registration by Mingyuan Zhao, Long Xu

“…To enhance robustness against outliers, Welsch function is selected as a robust kernel, efficiently solving the optimization using the Majorization-Minimization algorithm. …”
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Data-driven cultural background fusion for environmental art image classification: Technical support of the dual Kernel squeeze and excitation network. by Chenchen Liu, Haoyue Guo

“…On this basis, the Rectified Linear Unit activation function and depthwise convolution are introduced after the second layer convolution, and batch normalization is performed to improve the efficiency and robustness of feature extraction. …”
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Ethanol alters mechanosensory habituation in C. elegans by way of the BK potassium channel through a novel mechanism. by Nikolas Kokan, Conny Lin, Alvaro Luna, Joani Viliunas, Catharine H Rankin

“…In this research, we investigated how alcohol modulates the simplest form of learning, habituation, in Caenorhabditis elegans. …”
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Interleukin-15, IL-15 Receptor-Alpha, and Obesity: Concordance of Laboratory Animal and Human Genetic Studies by LeBris S. Quinn, Barbara G. Anderson

“…Deletions of IL15 in humans and mice are associated with obesity, while gain-of-function IL-15 overexpressing mice are resistant to diet-induced obesity. …”
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An Efficient Algorithm for Small Livestock Object Detection in Unmanned Aerial Vehicle Imagery by Wenbo Chen, Dongliang Wang, Xiaowei Xie

“…To capture high-level semantic features, we introduce the Large Kernel Attentions Spatial Pyramid Pooling (LKASPP) module. In addition, we replaced the original CIoU with the WIoU v3 loss function. …”
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B lymphocytes can be activated to act as antigen presenting cells to promote anti-tumor responses. by Renata Ariza Marques Rossetti, Noely Paula Cristina Lorenzi, Kaori Yokochi, Maria Beatriz Sartor de Faria Rosa, Luciana Benevides, Paulo Francisco Ramos Margarido, Edmund Chada Baracat, Jesus Paula Carvalho, Luisa Lina Villa, Ana Paula Lepique

“…B lymphocytes may display a pro-tumoral role but can also be modulated to function as antigen presenting cells to T lymphocytes, capable of triggering anti-cancer immune responses. …”
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DHS-YOLO: Enhanced Detection of Slender Wheat Seedlings Under Dynamic Illumination Conditions by Xuhua Dong, Jingbang Pan

“…Third, we implement the ShapeIoU loss function that prioritizes geometric consistency between predicted and ground truth bounding boxes, particularly optimizing for slender plant structures. …”
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Phytotherapy in Substance Abuse Management: An Evidence-based Mini Review by Asgar Nazir, Nasir Nazir Wani, Ajaz Ahmad Bhat, Farhaan Yaqoob

“…Silybum marianum and Piper methysticum: Improve liver function in alcohol-related disorders but need further study. …”
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Network-based pharmacological examination of the potential effector mechanisms of Achyranthes bidentata on osteoarthritis treatment by Junfeng WANG, Xuefeng GUAN, Yongju YANG, Pengpeng LIU, Tao LIU, Qun WANG

“…The Bioconductor data package was used in R to evaluate GO biological function enrichment and KEGG pathway enrichment, and the effective components and targets of Achyranthes bidentata in the treatment of osteoarthritis were acquired. …”
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Rice disease detection method based on multi-scale dynamic feature fusion by Qian Fan, Runhao Chen, Bin Li

“…The bounding box regression loss function, inner-WIoU, utilizes auxiliary bounding boxes and scale factors. …”
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Error Performance of DDPSK Receiver in the Presence of Composite Fading by Goran T. Djordjevic, Milica Petkovic, Nenad Milosevic, Bane Vasic

“…When shadowed multipath fading is modeled using the Fisher-Snedecor <inline-formula> <tex-math notation="LaTeX">$\mathcal {F}$ </tex-math></inline-formula> distribution, we present the probability density function (PDF) of the received composite signal phase in the form of the Fourier series and derive novel analytical expressions for its Fourier coefficients. …”
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SUMOylation Regulates Neutrophil Phagocytosis and Migration by Ran Zhang, Wanying Miao, Jin Zhang, Xinyuan Yu, Lihong Dang, Ata Ur Rehman, Feng Xu, Huaxin Sheng, G. Chad Hughes, Joseph P. Mathew, Jörn Karhausen, Wei Yang

“…Here, we examined the role of the small ubiquitin-like modifier (SUMO) conjugation in modulating neutrophil functional changes in the inflammatory microenvironment. …”
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Genome-wide association study-driven identification of thrombomodulin and factor V as the best biomarker combination for deep vein thrombosis by Usi Sukorini, Gisca Ajeng Widya Ninggar, Mohammad Hendra Setia Lesmana, Lalu Irham, Wirawan Adikusuma, Hegaria Rahmawati, Nur Imma Fatimah Harahap, Chiou-Feng Lin, Rahmat Dani Satria

“…THBD and F5 genes were selected based on their elevated expression levels in blood and the presence of eQTLs. Functionally, THBD modulates coagulation via protein C activation, while F5 is pivotal in thrombin formation and clot stabilization, underscoring their mechanistic relevance to DVT pathogenesis, and rendering them suitable for non-invasive clinical assessment. …”
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