FAViTNet: An Effective Deep Learning Framework for Non-Invasive Fetal Arrhythmia Diagnosis by Bipin Samuel, Malaya Kumar Hota

“…In this work, authors aim to develop a three-stage fetal arrhythmia detection framework comprised of 1) fECG extraction from abdominal Electrocardiogram (aECG) signal based on functional link neural network adaptive filter, 2) denoising of extracted fECG exploiting a generative adversarial network where the generator and the discriminator follow robust architectures, and 3) fetal arrhythmia detection based on FAViTNet architecture. …”
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Transcriptional landscape of pleural mesothelioma patients in relation to NF2 gene mutational status by Carlos Orozco-Castaño, Alejandro Mejía-Garcia, Hsuan Megan Tsao, Diego A. Bonilla, Carlos Carvajal-Fierro, Ricardo Bruges-Maya, Alba Combita, Rafael Parra-Medina

“…Logistic regression was used to evaluate associations with clinical variables, while transcriptomic differences were examined through differential expression and functional enrichment analyses. Immune and stromal infiltration were inferred via the xCell algorithm, cytokine signaling analyzed with Cytosig, and chemotherapeutic sensitivity predicted using the pRRophetic R package. …”
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Muscarinic cannabinoid suppression of excitation, a novel form of coincidence detection by Michaela Dvorakova, Ken Mackie, Alex Straiker

“…Cultured autaptic hippocampal neurons express all of these, illustrating the rich functional and temporal heterogeneity of CB1 at a single set of synapses. …”
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Fish MicroRNA Responses to Thermal Stress: Insights and Implications for Aquaculture and Conservation Amid Global Warming by Ting Lin, Madhava Meegaskumbura

“…Future research should focus on experimentally confirming their regulatory roles through functional assays, conducting transcriptomic comparisons across different species, and performing target validation studies. …”
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Extent, causes, and consequences of small RNA expression variation in human adipose tissue. by Leopold Parts, Åsa K Hedman, Sarah Keildson, Andrew J Knights, Cei Abreu-Goodger, Martijn van de Bunt, José Afonso Guerra-Assunção, Nenad Bartonicek, Stijn van Dongen, Reedik Mägi, James Nisbet, Amy Barrett, Mattias Rantalainen, Alexandra C Nica, Michael A Quail, Kerrin S Small, Daniel Glass, Anton J Enright, John Winn, MuTHER Consortium, Panos Deloukas, Emmanouil T Dermitzakis, Mark I McCarthy, Timothy D Spector, Richard Durbin, Cecilia M Lindgren

“…Small RNAs are functional molecules that modulate mRNA transcripts and have been implicated in the aetiology of several common diseases. …”
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Influence of supporting teeth quantity of surgical guide on the accuracy of the immediate implant in the maxillary central incisor: an in vitro study by Meo Nguyen, Huynh Kim Khanh Nguyen, Thien Nga Nguyen, Nam Cong-Nhat Huynh

“…Abstract Introduction Guided surgery for immediate anterior implants aims to reduce the time required for aesthetic and functional immediate loading. However, the limited surface area of anterior teeth for guide stabilization may affect the accuracy of implant positioning. …”
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The association between the Mediterranean Diet and the prime diet quality score and new-diagnosed irritable bowel syndrome: a matched case-control study by Ghazal Baghdadi, Marzieh Feyzpour, Seyedeh Atiye Shahrokhi, Roksaneh Amiri, Mehran Rahimlou

“…BackgroundIrritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder with multifactorial etiology. …”
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Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection. by Sara Rodríguez-Martín, Kai Alexander Kropp, Vanessa Wilhelmi, Vanda Juranic Lisnic, Wei Yuan Hsieh, Mathieu Blanc, Andrew Livingston, Andreas Busche, Hille Tekotte, Martin Messerle, Manfred Auer, Iain Fraser, Stipan Jonjic, Ana Angulo, Matthias J Reddehase, Peter Ghazal

“…Little is known about the role of viral genes in modulating host cytokine responses. Here we report a new functional role of the viral encoded IE1 protein of the murine cytomegalovirus in sculpting the inflammatory response in an acute infection. …”
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Hmgb3 is regulated by microRNA-206 during muscle regeneration. by Simona Maciotta, Mirella Meregalli, Letizia Cassinelli, Daniele Parolini, Andrea Farini, Giulia Del Fraro, Francesco Gandolfi, Mattia Forcato, Sergio Ferrari, Davide Gabellini, Silvio Bicciato, Giulio Cossu, Yvan Torrente

“…In this study we identify fourteen miRNAs associated to dystrophic fibres responsible for muscle regeneration and remodelling, and confirm over-expression of the previously identified regeneration-associated myomiR-206. In particular, a functional binding site for myomiR-206 was identified and validated in the 3'untranslated region (3'UTR) of an X-linked member of a family of sequence independent chromatin-binding proteins (Hmgb3) that is preferentially expressed in hematopoietic stem cells. …”
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Developmental and Temperature-Driven Variations in Metabolic Profile and Antioxidant Capacity of Broccoli (<i>Brassica oleracea</i> var. <i>cymosa</i>) by Daria Gmižić, Ivana Šola

“…These findings underscore the complexity of metabolic regulation in broccoli and emphasize the importance of considering both developmental stage and environmental conditions when assessing its nutritional and functional properties.…”
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In Vitro Ruminal Metagenomic Profiles and Ruminal Fermentation Variables of Aromatic Plant Pulps by Kanber Kara, Sena Yilmaz Öztaş, Erol Baytok

“…Conclusion Due to their fermentability and favourable microbial responses, aromatic plant pulps, particularly yarrow, show promise as functional ruminant feed ingredients. These byproducts may enhance ruminal fibre utilization while modulating microbial ecology and reducing methane‐associated archaea.…”
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Biochar and neem seed cake co-amendment effects on soil nitrogen cycling and NH3 volatilization in contrasting soils by Segun O. Oladele, Ajoke C. Adegaye, Adeola Wewe, Taiwo M. Agbede, Adedolapo A. Adebo

“…Abstract In a 28-day incubation study, ball milling technologies were applied to enhance the sorptive and functional properties of pristine biochar. The effect of ball-milled (BM) biochar, neem seed cake, and their co-amendment was evaluated on nitrification, ammonia (NH3) volatilization, and the abundance of nitrifying microbial communities in three contrasting tropical soils of different pH (acidic, neutral, and alkaline). …”
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miR-221 is a prognostic marker and promotes the proliferation and migration of esophageal squamous cell carcinoma by inhibiting autophagy by Kun Mei, Zilu Chen, Foxing Tan, YuHeng Zhou, Haolin Du, Renjun Gu, Yan Huang

“…While the functional roles of numerous miRNAs in ESCC remain incompletely understood, existing studies have implicated autophagy deficiency in aging, cancer, and neurodegenerative diseases. …”
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Microiontophoretic Application of Dynorphin in Dental Pain: Excitatory or Inhibitory Effects by Choi SH, Kim YM, Son JY, Ahn DK

“…While prior research has identified dynorphin expression in layers I–II of the dorsal horn across the spinal cord in various pain models, its functional role in trigeminal nociception, including tooth pain, remains underexplored. …”
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Contrasting dynamics and environmental controls of dispersed bacteria along a hydrologic gradient by Clara Ruiz-González, Juan Pablo Niño-García, Martin Berggren, Paul A. del Giorgio

“…Here we aimed at exploring the environmental factors driving the structure of such contrasting bacterial populations as well as their functional properties. Using Illumina sequencing of the 16S rRNA gene, we characterized the taxonomic composition of bacterioplankton communities from 10 streams and rivers in Québec spanning the whole hydrologic continuum (river Strahler order 0 to 7), which were sampled in two occasions. …”
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Protective Effect of Creatine Elevation against Ischaemia Reperfusion Injury Is Retained in the Presence of Co-Morbidities and during Cardioplegia. by Hannah J Whittington, Debra J McAndrew, Rebecca L Cross, Stefan Neubauer, Craig A Lygate

“…CrT-OE hearts exhibited significantly improved functional recovery (Rate pressure product) during reperfusion compared to WT littermates (76% of baseline vs. 59%, respectively, P = 0.02). …”
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Mapping and visualization of global research progress on autophagy in metabolic dysfunction-associated steatotic liver disease and metabolic syndrome: a bibliometric analysis (2009... by Xing Liu, Xiang Li

“…Future research is anticipated to concentrate on the activation of autophagy in the context of natural product drug discovery, the exploration of underlying molecular mechanisms, the regulation of fatty acid metabolism, and the development of functional nutritional supplements, among other relevant areas.…”
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Application of Standardized <i>Rosa damascena</i> Stem Cell-Derived Exosomes in Dermatological Wound Healing and Scar Management: A Retrospective Case-Series Study with Long-Term O... by Lidia Majewska, Agnieszka Kondraciuk, Karolina Dorosz, Agnieszka Budzyńska

“…In traumatic facial injury, RSCE therapy facilitated reduction in scar contracture and improved functional outcomes. For atrophic acne scars, comparative treatment of facial sides showed enhanced results with RSCE addition. …”
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Exploring the potential of approved drugs for triple-negative breast cancer treatment by targeting casein kinase 2: Insights from computational studies. by Tagyedeen H Shoaib, Walaa Ibraheem, Mohammed Abdelrahman, Wadah Osman, Asmaa E Sherif, Ahmed Ashour, Sabrin R M Ibrahim, Kholoud F Ghazawi, Samar F Miski, Sara A Almadani, Duaa Fahad ALsiyud, Gamal A Mohamed, Abdulrahim A Alzain

“…Additionally, Density functional theory (DFT) calculations were performed on a complex of etravirine and a representative gold atom positioned at different sites relative to the heteroatoms of etravirine. …”
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Intradermally Administered Retinoic Acid or Vitamin D3-Loaded Liposomes Induce Tolerogenic Skin Dendritic Cells by Noémi Anna Nagy, Sanne G. Celant, Toni M. M. van Capel, Rinske Sparrius, Fernando Lozano Vigario, Ronald van Ree, Bram Slütter, Teunis B. H. Geijtenbeek, Sander W. Tas, Esther C. de Jong

“…Migrated DCs from RA or VD3 liposome-injected skin differentiated naïve CD4+ T cells into FoxP3+ CD127 low and ICOS+ Tregs, expressing functional regulatory markers. Thus, our findings provide further substantiation for in vivo DC-modulating vaccines with tolerogenic liposomes as a putative clinical therapy for autoimmune diseases and allergies.…”
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