Green forage impacts on the DNA methylation in the ruminal wall of Italian mediterranean dairy buffaloes by Salvatore Fioriniello, Angela Salzano, Giovanna Bifulco, Riccardo Aiese Cigliano, Floriana Della Ragione, Giuseppe Campanile

“…Our findings highlighted the impact of green forage on rumen DNA methylation, which potentially influences molecular mechanisms relevant to rumen functionality and, then, animal welfare and production, through the modulation of gene expression.…”
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Synthesis of Diversely Substituted Diethyl (Pyrrolidin-2-Yl)Phosphonates by Andrea Bagán, Alba López-Ruiz, Sònia Abás, Elies Molins, Belén Pérez, Itziar Muneta-Arrate, Luis F. Callado, Carmen Escolano

“…Although the levels of I₂-IR are dysregulated in a plethora of illnesses, the arsenal of ligands that can modulate I₂-IR is limited. In this framework, we have reported several new structural families embodying the iminophosphonate functional group that have an excellent affinity and selectivity for I₂-IR, and selected members have demonstrated relevant pharmacological properties in murine models of neurodegeneration and Alzheimer’s disease. …”
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Adenosine Receptors as a Biological Pathway for the Anti-Inflammatory and Beneficial Effects of Low Frequency Low Energy Pulsed Electromagnetic Fields by Katia Varani, Fabrizio Vincenzi, Annalisa Ravani, Silvia Pasquini, Stefania Merighi, Stefania Gessi, Stefania Setti, Matteo Cadossi, Pier Andrea Borea, Ruggero Cadossi

“…Of particular interest is the observation that PEMFs, acting as modulators of adenosine, are able to increase the functionality of the endogenous agonist. …”
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Input–output organization of the mouse BLA-projecting IL neurons by Zhuo Li, Zhuo Li, Yu Qu, Yu Qu, Qi-Lin Wu, Li Tang, Yuan Dong, Yuan Dong, Xu-Feng Xu, Xu-Feng Xu

“…IntroductionThe infralimbic cortex (IL), a critical subregion within the ventromedial prefrontal cortex (vmPFC), modulates emotion, memory, and social functions via robust projections to the basolateral amygdala (BLA). …”
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Probiotic-derived extracellular vesicles: the next breakthrough in postbiotics for rheumatoid arthritis by Federica Dell’Atti, Federica Dell’Atti, Hugo Abreu, Hugo Abreu, Patrizia Malfa, Davide Raineri, Davide Raineri, Giuseppe Cappellano, Giuseppe Cappellano, Annalisa Chiocchetti, Annalisa Chiocchetti

“…These bioactive nanoparticles transport functional metabolites capable of modulating immune responses, reducing inflammation, and restoring gut barrier integrity. …”
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ESMII-Net: An edge-synergy and multidimensional information interaction network for remote sensing change detection by Yixin Chen, Xiaogang Ning, Ruiqian Zhang, Hanchao Zhang, Xiao Huang, You He

“…Furthermore, during the loss function formulation, we have incorporated a Small Object Enhancement Factor (SOEF) to prioritize small object detection. …”
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Study on PV Defect Detection Based on CWE YOLOv8 by Xiaojuan Zhang, Ruixu Yao, Bo Jing, Xiaoxuan Jiao, Mengdi Ren

“…To improve feature extraction for small or blurry defects, the C2f-DySnakeConv module is added to the backbone network. The traditional upsampling process is replaced by the WaveletPool module, which uses wavelet transforms to enhance multi-scale features and improve feature resolution. …”
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Postbiotic Sodium Butyrate Mitigates Hypertension and Kidney Dysfunction in Juvenile Rats Exposed to Microplastics by You-Lin Tain, Ying-Jui Lin, Chih-Yao Hou, Guo-Ping Chang-Chien, Shu-Fen Lin, Chien-Ning Hsu

“…Results: High-dose MP exposure impaired kidney function and increased blood pressure, which were alleviated by sodium butyrate through reduced oxidative stress, modulation of gut microbiota, increased plasma butyric acid levels, and enhanced renal SCFA-sensing G protein-coupled receptor 43 expression. …”
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Modified Lipid Particle Recognition: A Link Between Atherosclerosis and Cancer? by Amy E. Hall, Dhananjay Jade, Faheem Shaik, Shervanthi Homer-Vanniasinkam, Stephen P. Muench, Michael A. Harrison, Sreenivasan Ponnambalam

“…Inhibition of LOX-1 function could thus provide new therapeutic strategies for targeting both atherosclerosis and cancer.…”
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Hyper-LKCNet: Exploring the Utilization of Large Kernel Convolution for Hyperspectral Image Classification by Rong Liu, Zhilin Li, Jiaqi Yang, Jian Sun, Quanwei Liu

“…The AGF classifier, derived by neural collapse theory, alleviates the sample imbalance problem and incorporates the label smoothing focal loss function to enhance generalization ability. Extensive experiments on four HSI datasets demonstrate that the proposed method outperforms the state-of-the-art approaches. …”
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An algorithm for cardiac disease detection based on the magnetic resonance imaging by Heng Li, Qingni Yuan, Yi Wang, Pengju Qu, Chunhui Jiang, Hu Kuang

“…Firstly, the standard Spatial Pyramid Pooling Fast module is replaced with a Multi-Channel Spatial Pyramid Pooling module. …”
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Unraveling the advances of non-coding RNAs on the tumor microenvironment: innovative strategies for cancer therapies by Deyang Mu, Bing Han, Hao Huang, Yuchen Zheng, Jungang Zhang, Ying Shi

“…Our review covers the structure and functions of different ncRNAs, such as microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs). …”
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SCRV-induced miR-365–3p inhibits viral replication by targeting OTUD7B-mediated autophagy in silver carp (Hypophthalmichthys molitrix) by Kun Gao, Meng Liu, Hanyu Pan, Yiming Wei, Xiaofeng Shan, Guiqin Wang, Xiuyun Jiang, Yunhang Gao

“…The regulatory functions of microRNAs (miRNAs) in modulating viral pathogenesis have emerged as a pivotal research focus. …”
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Cu(I)-catalysed chemo-, regio-, and stereoselective radical 1,2-carboalkynylation with two different terminal alkynes by Jun-Qian Bian, Li Qin, Li-Wen Fan, Jiajia Fu, Yong-Feng Cheng, Yu-Feng Zhang, Qiao Song, Peng-Fei Wang, Zhong-Liang Li, Qiang-Shuai Gu, Peng Yu, Jun-Bin Tang, Xin-Yuan Liu

“…This method features good substrate scope, high functional group tolerance of two different terminal alkynes, and diverse alkyl halides, providing universal access to a series of useful axially chiral 1,3-enyne building blocks.…”
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Deciphering the mechanisms of long non-coding RNAs in ferroptosis: insights into its clinical significance in cancer progression and immunology by Shengming Ou, Xiaoya Nie, Xiangyu Qiu, Xin Jin, Geyan Wu, Rongxin Zhang, Jinrong Zhu

“…Long non-coding RNAs (LncRNAs) are a group of functional RNA molecules that are not translated into proteins, which can regulate gene expression in various manners. …”
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Immunomodulatory Effects of RAAS Inhibitors: Beyond Hypertension and Heart Failure by Raluca Ecaterina Haliga, Elena Cojocaru, Oana Sîrbu, Ilinca Hrițcu, Raluca Elena Alexa, Ioana Bianca Haliga, Victorița Șorodoc, Adorata Elena Coman

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Teleost fish metamorphosis under the influence of estrogenic hormones: targeting the thyroid axis – a literature review by Nathalie Leroux, Sébastien Baekelandt, Patrick Kestemont

“…Nonetheless, available studies suggest that estrogens are potent modulators of thyroid function at multiple levels of the hormonal cascade. …”
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Li+ Diffusion in LinCoNb2O6 (0 < n ≤ 6) Anode with High Capacity Density: Fast Kinetics and Mechanistic Insights by Yimo Xiang, Shaowen Tan, Jingxian Yu, Shengping Wang

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Applying Machine Learning Techniques to Identify Undiagnosed Patients with Exocrine Pancreatic Insufficiency by Bruce Pyenson, Maggie Alston, Jeffrey Gomberg, Feng Han, Nikhil Khandelwal, Motoharu Dei, Monica Son, Jaime Vora

“…# Background Exocrine pancreatic insufficiency (EPI) is a serious condition characterized by a lack of functional exocrine pancreatic enzymes and the resultant inability to properly digest nutrients. …”
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Calponin 3 Regulates Myoblast Proliferation and Differentiation Through Actin Cytoskeleton Remodeling and YAP1-Mediated Signaling in Myoblasts by Mai Thi Nguyen, Quoc Kiet Ly, Thanh Huu Phan Ngo, Wan Lee

“…This study investigated the functional significance of CNN3 in myogenic differentiation, along with its effects on actin remodeling and mechanosensitive signaling in C2C12 myoblasts. …”
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