CD24 Regulates the Formation of Ectosomes in B Lymphocytes by Hong‐Dien Phan, Kaitlyn E. Mayne, Willow R. B. Squires, Grant R. Kelly, Reilly H. Smith, Rashid Jafardoust, Sherri L. Christian

“…We previously reported that stimulation of CD24 on donor B cells promotes the transfer of functional receptors to recipient B cells via extracellular vesicles (EVs). …”
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Cerebral Blood Flow Measurement Using fMRI and PET: A Cross-Validation Study by Jean J. Chen, Marguerite Wieckowska, Ernst Meyer, G. Bruce Pike

“…An important aspect of functional magnetic resonance imaging (fMRI) is the study of brain hemodynamics, and MR arterial spin labeling (ASL) perfusion imaging has gained wide acceptance as a robust and noninvasive technique. …”
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Dysregulated microRNAs in blood correlate with central nervous system neuropathology of prion disease by Sonia Pérez-Lázaro, Inmaculada Martín-Burriel, Luca Cozzuto, Julia Ponomarenko, Juan J. Badiola, Rosa Bolea, Janne M. Toivonen

“…These findings highlight the relevance of circulating miRNAs in prion neuropathology and support further research into the specific functional roles of these miRNAs and their predictive capacity for disease progression.…”
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Microencapsulated inulin as a prebiotic: Enhancing growth, digestive enzyme activity, and immune response in striped catfish (Pangasianodon hypophthalmus) by Supalug Kattakdad, Nittaya Phungam, Urailuck Pongket, Woranit Muangmala, Suriya Udduang, Siti Ariza Aripin, Bundit Yuangsoi

“…These results support the use of microencapsulated inulin, particularly at 0.8 %, as an effective functional feed additive to enhance growth, immune defense, and tissue integrity in striped catfish culture.…”
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Digital Twin-Enabled Adaptive Robotics: Leveraging Large Language Models in Isaac Sim for Unstructured Environments by Sanjay Nambiar, Rahul Chiramel Paul, Oscar Chigozie Ikechukwu, Marie Jonsson, Mehdi Tarkian

“…The proposed framework advances toward a fully functional digital twin by integrating real-time perception and intuitive human–robot interaction capabilities. …”
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Ovotransferrin-depleted egg white hydrolysate reduces blood pressure in spontaneously hypertensive rats by Fatemeh Ashkar, Hongbing Fan, Zihan Wang, Ilekuttige Priyan Shanura Fernando, Jianping Wu

“…These findings demonstrate the potential of OD-EWH as a functional food ingredient against hypertension.…”
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Brain network of athletes in motor imagery and action anticipation: an ALE meta-analysis and MACM analysis by Yanqiu Wang, Yang Sun, Jiangsheng Yu, Xiaorong Cheng, Zhebin Niu

“…We systematically reviewed functional magnetic resonance imaging studies and included 20 eligible studies. …”
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Comprehensive characterization of multi-omics landscapes between gut microbial metabolites and the druggable genome in sepsis by Jun Liu, Tong Li, Li Xin, Xingyu Li, Jianbo Zhang, Peng Zhu

“…Key findings were validated by molecular dynamics (MD) simulation, microscale thermophoresis (MST), and functional assays in a murine cecal ligation and puncture (CLP) model of sepsis.ResultsWe evaluated 190,950 metabolite-protein interactions, linking 114 sepsis-related GIK targets to 335 gut microbial metabolites, and prioritized indole-3-lactic acid (ILA), a metabolite enriched in Akkermansia muciniphila, as a promising therapeutic candidate. …”
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Deciphering the secrets of tumor-initiating cells in pancreatic ductal adenocarcinoma microenvironment: mechanisms and therapeutic opportunities by Jun Zhou, Jiajun Li, Jiajun Li, Haoyi Lu, Yanggang Hong, Yanggang Hong

“…This review outlines the molecular features and functional roles of PaCSCs, their interaction with the TME, and recent advances in targeting this CSC-stroma network. …”
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Integrating neuroscience and oncology: neuroimmune crosstalk in the initiation and progression of digestive system tumors by Haonan Sun, Tao Wang, Xiangyan Jiang, Mingdou Li, Xiaoe He, Yong Ma, Xiangkai Li, Weilin Jin, Zuoyi Jiao

“…On this anatomical foundation, our review delves into the functional significance of these interactions, emphasizing the bidirectional regulatory pathways between the nervous system and tumor cells during disease progression and highlighting their intricate crosstalk with the immune microenvironment. …”
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“Exploring the efficacy and mechanistic action of traditional Chinese medicine-derived phytochemicals in rheumatoid arthritis” by Uma Palanikumar, Rajagopal Balasubramanian, Prasanna Seenivasan, Vellaikumar Sampathrajan, Thangavelu AU

“…Introduction: Rheumatoid arthritis [RA] is an autoimmune chronic inflammatory condition that leads to joint degeneration and functional disability. The most advanced pharmacological therapies that have been available for a long time remain limited, as they are associated with adverse effects and incomplete disease remission. …”
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An Image-Based Alignment Errors Correction Method for Segmented Fresnel Primary Mirror by Licheng Zhu, Ping Yang, Lianghua Wen, Lujia Zhao, Chunlin Guan, Bing Xu

“…Based on the linear relationship between five kinds of alignment errors and modulation transfer function metric or image frequency domain metric, an iterative correction method is introduced to compensate the alignment errors of segmented Fresnel lens at five degrees of freedom. …”
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Sphingolipids as Mediators in the Crosstalk between Microbiota and Intestinal Cells: Implications for Inflammatory Bowel Disease by Phillips-Farfán Bryan, Carvajal Karla, Medina-Torres Edgar Alejandro, Espinosa-Padilla Sara Elva, Fabrias Gemma, Camacho Luz

“…Interestingly, it seems that microorganisms of the normal gut microbiota and probiotics are involved in sphingolipid function. However, there is a great need to investigate the role of SLs as intermediates in the crosstalk between intestinal immunity and microorganisms. …”
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Ketone bodies in exercise, health and disease: Metabolic mechanisms, pathophysiology, and therapeutic implications by Yin Li, Qingyi Liu, Zhihao Jia, Bin Guo

“…Recent advances have underscored the importance of ketone bodies in exercise physiology and muscle function. Excessive or impaired ketone handling underlies diabetic ketoacidosis and contributes to the pathogenesis of selected neurodegenerative, cardiovascular and neoplastic disorders. …”
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Enhancing antitumor immunity: the role of immune checkpoint inhibitors, anti-angiogenic therapy, and macrophage reprogramming by Chong Zhang, Hua Wang, Hua Wang, Xinying Li, Yuxin Jiang, Guoping Sun, Hanqing Yu

“…Moreover, we explore the potential of macrophage reprogramming to bolster anti-tumor immunity, with a focus on restoring macrophage phagocytic function, modulating hypoxic tumor environments, and targeting cytokines and chemokines that shape immune responses. …”
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Tertiary lymphoid structures in the microenvironment of colorectal cancer: exploring new therapeutic targets by Nan-Nan Dai, Man-Yi Hu, Jian-Ping Wang, Zhi-Hui Dai, Li Xu, Tai-Wei Ye

“…The formation of TLS formation dynamically adapts to the tumor microenvironment, with their immune function maintained by resident immune cells and cytokine networks. …”
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Oleic acid restores the impaired antitumor immunity of γδ-T cells induced by palmitic acid by Yanmei Zhang, Zheng Xiang, Yan Xu, Lo Sha Cheung, Xiwei Wang, Manni Wang, Howard Ho Wai Wong, Zhenyao Zhu, Wenyue Zhang, Yifan Gao, Xianze Luo, Yin Celeste Cheuk, Yixin Zhou, Xianfeng Zha, Yashi Chen, Man Li, Feifei Luo, Yiwei Chu, Yu-Lung Lau, Yinping Liu, Wenwei Tu

“…This study highlights a novel mechanism whereby dietary FAs modulate γδ-T cell function through regulating IFNγ-mediated pyroptosis. …”
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Increased cardiac myosin super-relaxation as an energy saving mechanism in hibernating grizzly bears by Robbert J. Van der Pijl, Weikang Ma, Christopher T.A. Lewis, Line Haar, Amalie Buhl, Gerrie P. Farman, Marcus Rhodehamel, Vivek P. Jani, O Lynne Nelson, Chengxin Zhang, Henk Granzier, Julien Ochala

“…Conclusions: Cardiac myosin depresses the heart's energetic demand during hibernation by modulating its function.…”
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Balancing CIK Cell Cancer Immunotherapy and PPAR Ligands: One Potential Therapeutic Application for CNS Malignancies by Kira Vordermark, JingJing Pu, Amit Sharma, Jarek Maciacyzk, Ingo G. H. Schmidt‐Wolf

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Breastfeeding and early Bifidobacterium-driven microbial colonization shape the infant gut resistome by Anna Samarra, Alejandro J. Alcañiz, Cecilia Martínez-Costa, Alberto Marina, Iñaki Comas, Nicola Segata, Narciso M. Quijada, Maria Carmen Collado

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