Adapting language generation to dialogue environments and users for task-oriented dialogue systems by Atsumoto Ohashi, Ryuichiro Higashinaka

“…In ANTOR, a natural language understanding (NLU) module, which corresponds to the user’s understanding of system utterances, is incorporated into the objective function of RL. …”
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USP5 inhibits anti-RNA viral innate immunity by deconjugating K48-linked unanchored and K63-linked anchored ubiquitin on IRF3. by Zigang Qiao, Dapei Li, Fan Zhang, Jingfei Zhu, Siying Liu, Xue Bai, Haiping Yao, Zhengrong Chen, Yongdong Yan, Xiulong Xu, Feng Ma

“…Interferon regulatory factor 3 (IRF3) is a central hub transcription factor that controls host antiviral innate immunity. The expression and function of IRF3 are tightly regulated by the post-translational modifications. …”
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Postprandial Hypotension in Elderly Patients: Pathophysiology, Diagnosis and Prevention Measures by O. N. Antropova, A. A. Efremushkina

“…Possible pathophysiological mechanisms of PPG: increased visceral blood flow; weakening of baroreflex function due to disorders associated with age or autonomic dysfunction; inappropriate activation of sympathetic nerves; dysregulation of vasoactive intestinal peptides; insulin-mediated vasodilation. …”
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Thermostabilization of the Human Serotonin Transporter in an Antidepressant-Bound Conformation. by Evan M Green, Jonathan A Coleman, Eric Gouaux

“…This thermostability screening protocol, as well as the specific hSERT variants, will prove useful in studies of other integral membrane receptors and transporters and in the investigation of structure and function relationships in hSERT.…”
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Patrones constructivos de enfriamiento pasivo para mampostería cerámica de bajo costo by Marlyn Stephanny Narváez-Ortega, Jorge Sánchez-Molina, Carmen Xiomara Diaz-Fuentes

“…Thermal simulations are applied to analyze temperature distribution and heat flow profiles in 6 construction systems with passive cooling patterns in the form and function of the exterior surfaces. For the analysis, the models are exposed to the most extreme climatic conditions of a hot semi-arid climate taking as reference the periods of highest temperature and solar radiation in Cúcuta, Colombia to determine the thermal performance of the different configurations and evaluate the viability of the solutions. …”
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Age and Smoking Related Changes in Metal Ion Levels in Human Lens: Implications for Cataract Formation. by Alex Langford-Smith, Viranga Tilakaratna, Paul R Lythgoe, Simon J Clark, Paul N Bishop, Anthony J Day

“…These changes in metal ions, i.e. that occur as a consequence of normal ageing and of smoking, could contribute to cataract formation via induction of oxidative stress pathways, modulation of extracellular matrix structure/function and cellular toxicity. …”
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The ESCRT-0 component HRS is required for HIV-1 Vpu-mediated BST-2/tetherin down-regulation. by Katy Janvier, Annegret Pelchen-Matthews, Jean-Baptiste Renaud, Marina Caillet, Mark Marsh, Clarisse Berlioz-Torrent

“…We demonstrate that Vpu-mediated BST-2/tetherin down-modulation and degradation require HRS (ESCRT-0) function and that knock down of HRS increases cellular levels of BST-2/tetherin and restricts virus release. …”
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SLFN11: a pan-cancer biomarker for DNA-targeted drugs sensitivity and therapeutic strategy guidance by Kunzhong Zhou, Yuewen Li, Weifang Wang, Yilin Chen, Bingyan Qian, Yiteng Liang, Hongmei Li, Ruiting Xu, Li Zhuang

“…In this review, we summarize the structure and function of SLFN11, as well as its progress as a biomarker across various cancer types. …”
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Anti-inflammatory effects of glucagon-like peptide-1 (GLP-1) in coronary artery disease: a comprehensive review by Alicja Skrobucha, Patryk Pindlowski, Natalia Krajewska, Marcin Grabowski, Szymon Jonik

“…However, beneficial impact of GLP-1 on endothelial function and microcirculatory integrity in patients with CAD have been described. …”
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Skin Lesion Image Segmentation Algorithm Based on MC-UNet by Guihua Yang, Bingxing Pan

“…Finally, the network’s segmentation accuracy is improved through the use of a new loss function called MixLoss, which combines BceLoss and DiceLoss. …”
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Flexible sensors for food monitoring. Part I: Principle by D. Luo, M. A. Nikitina, X. Xiao

“…In addition, this review elaborates on the transduction mechanisms of several typical transducers, with a focus on the physics behind, including the modulation of doping level, Schottky barrier, and interfacial layer that typically lead to changes in conductivity, work function, and permittivity. …”
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Smart Car Damage Assessment Using Enhanced YOLO Algorithm and Image Processing Techniques by Muhammad Remzy Syah Ramazhan, Alhadi Bustamam, Rinaldi Anwar Buyung

“…The enhancements include the convolutional block attention module (CBAM), applied to the backbone layer to enhance the model’s ability to focus on key damaged regions, and the SCYLLA-IoU (SIoU) loss function, introduced for bounding box regression. …”
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The Aminopeptidase CD13 Induces Homotypic Aggregation in Neutrophils and Impairs Collagen Invasion. by Christine A Fiddler, Helen Parfrey, Andrew S Cowburn, Ding Luo, Gerard B Nash, Gillian Murphy, Edwin R Chilvers

“…Apart from our demonstration that CD13 modulates the efficacy of tumor necrosis factor-α-induced apoptosis in neutrophils, no other function for CD13 has been ascribed in this cell. …”
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Effect of enhanced early life nutrition on the M. longissimus thoracis et lumborum transcriptome of crossbred beef heifer calves by Kate Keogh, Alan K. Kelly, David A. Kenny

“…Differentially expressed genes were involved in processes related to metabolism, energy production and cellular growth and proliferation and included enrichment of the Sirtuin signalling pathway and skeletal muscle system development and function. The results of this study identify novel gene transcripts involved in the molecular regulation of skeletal muscle response to nutritional modulation, offering insights into muscle development and its potential impact on tissue composition.…”
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THE ANALYSIS OF METHODS OF RECEPTION OF LONGITUDINAL PROFILE OF ROADS by V. G. Mikhailov

“…Though in the future in process of perfection of accuracy of sounding and availability of the information the given mode is represented to the most perspective.The method of registration of cross-sections/biases of the big sites of roads in the course of movement of the vehicle on the basis of microcontroller Arduino Due, the gauge of speedups and discharge angles MPU-6050 and data recording on a SD- card is offered, application of the combined processing of the information on the basis of the developed programs in language With in the microcontroller and in module S-Function Builder in package Matlab/Simulink is considered.By means of the offered methods registration of biases of road of difficult character by extent of 10 km is spent. …”
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Evaluation of Serum Leptin Levels and Growth in Patients with β-Thalassaemia Major by Lamia Mustafa Al-Naama, Meaad Kadum Hassan, Muhannad Maki Abdul Karim

“…Leptin plays a key role in the regulation of appetite, body fat mass, and endocrine function. Objectives. This study aimed to evaluate the relationship between serum leptin and growth and pubertal development in patients with β-TM, as well as whether serum leptin can predict growth retardation and delayed puberty in these patients. …”
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Dynamics of tissue repair regulatory T cells and damage in acute Trypanosoma cruzi infection. by Santiago Boccardo, Constanza Rodriguez, Camila M S Gimenez, Cintia L Araujo Furlan, Carolina P Abrate, Laura Almada, Manuel A Saldivia Concepción, Peter Skewes-Cox, Srinivasa P S Rao, Jorge H Mukdsi, Carolina L Montes, Adriana Gruppi, Eva V Acosta Rodríguez

“…Unlike sterile injury models, trTregs significantly declined in secondary lymphoid organs and non-lymphoid target tissues during infection, correlating with systemic and local tissue damage, and downregulation of function-associated genes in skeletal muscle. This decline was linked to decreased systemic IL-33 levels, a key trTreg growth factor, and promoted by the Th1 cytokine IFN-γ. …”
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An Improved Transformer-Based Model for Urban Pedestrian Detection by Tianyong Wu, Xiang Li, Qiuxuan Dong

“…We also introduce a novel loss function, InnerMPDIoU, to enhance detection efficacy in congested environments. …”
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Differential expression of exosomal microRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients. by Meredith G Banigan, Patricia F Kao, James A Kozubek, Ashley R Winslow, Juan Medina, Joan Costa, Andrea Schmitt, Anja Schneider, Howard Cabral, Ozge Cagsal-Getkin, Charles R Vanderburg, Ivana Delalle

“…Once secreted, exosomes are able to attach to recipient cells and release miRNAs potentially modulating the function of the recipient cell. We hypothesized that exosomal miRNA expression in brains of patients diagnosed with schizophrenia (SZ) and bipolar disorder (BD) might differ from controls, reflecting either disease-specific or common aberrations in SZ and BD patients. …”
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Campus risk detection using the S-YOLOv10-SIC network and a self-calibrated illumination algorithm by Qiang Zhao, Sha Liu, Shihao Zhang, Baijuan Wang

“…The algorithm optimizes the loss function by introducing an auxiliary bounding box, and accelerates model convergence. …”
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