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9061
The Beneficial Roles of Seaweed in Atopic Dermatitis
Published 2024-12-01“…This review explores the therapeutic potential of brown, red, and green algae in alleviating AD symptoms, highlighting the effects of specific species, including <i>Undaria pinnatifida</i>, <i>Laminaria japonica</i>, <i>Chlorella vulgaris</i>, and <i>Sargassum horneri</i>. These seaweeds modulate immune responses, reduce epidermal thickness, and restore skin barrier function, presenting a novel, safe, and effective approach to AD management. …”
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9062
Biologic and synthetic skin substitutes: An overview
Published 2010-09-01“…The current trend of burn wound care has shifted to more holistic approach of improvement in the long-term form and function of the healed burn wounds and quality of life. …”
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9063
1,25(OH)₂D₃ inhibits ferroptosis in nucleus pulposus cells via VDR signaling to mitigate lumbar intervertebral disc degeneration
Published 2025-03-01“…The findings indicate the therapeutic potential of 1,25(OH)₂D₃ in alleviating LIDD, presenting a new strategy to inhibit ferroptosis and maintain intervertebral disc function.…”
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9064
Kanamycin and G-Quadruplexes: An Exploration of Binding Interactions
Published 2024-12-01“…G-quadruplexes (G4s) are distinctive four-stranded nucleic acid structures formed by guanine-rich sequences, making them attractive targets for drug repurposing efforts. Modulating their stability and function holds promise for treating diseases like cancer. …”
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9065
Stimulus representation in human frontal cortex supports flexible control in working memory
Published 2025-04-01“…Here, we tested the hypothesis that stimulus representation persists in the frontal cortex to facilitate flexible control demands in WM. During functional MRI, participants flexibly switched between simple WM maintenance of visual stimulus or more complex rule-based categorization of maintained stimulus on a trial-by-trial basis. …”
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9066
Research Note: Comprehensive proteomic, phosphoproteomic, and N-glycoproteomic analysis of chicken egg yolk plasma
Published 2024-12-01“…Among the phosphorylation sites, tyrosine accounted for 80.6%, while the N-glycosylation sites predominantly featured “N-X-T” motifs, accounting for 58.7%. Functional enrichment analysis revealed that most proteins were involved in regulating enzyme activity and inhibition with a particular focus on modulating peptidase activity. …”
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9067
Gut–Vaginal Microbiome Crosstalk in Ovarian Cancer: Implications for Early Diagnosis
Published 2025-06-01“…This comprehensive review systematically examines the compositional alterations in and functional interplay between vaginal and intestinal microbial communities in ovarian cancer patients. …”
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9068
Deep generative model for the inverse design of Van der Waals heterostructures
Published 2025-07-01“…Experiments demonstrate that ConditionCDVAE+ achieves optimal root mean square error for crystal reconstruction, with improved generation quality. Density Functional Theory calculations confirms 99.51% of generated samples converge to energy minima, indicating superior ground-state convergence. …”
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9069
CGRPβ suppresses the pathogenesis of ulcerative colitis via the immunoproteasome
Published 2025-02-01“…Our findings suggest that functional differences in CGRP isoforms may influence the severity and management of UC. …”
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9070
Investigation of BMP6 mutations in Brazilian patients with iron overload
Published 2024-11-01“…Conclusion: BMP6 mutations, when combined to other genetic and clinical risk factors, may contribute to IO. Functional studies and THE evaluation of large cohorts are necessary to fully address BMP6 role in IO.…”
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9071
Scalable metal-based nanoparticle synthesis via laser ablation in liquids for transformative sensory and synaptic devices
Published 2025-01-01“…To address these demands, metal-based nanoparticles (NPs), such as noble metal, oxide, and multi-elemental NPs, have been extensively incorporated into functional materials of sensory and synaptic devices due to their tunable optical, electrical, and chemical properties, enhancing sensory precision, stability, and environmental adaptability. …”
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9072
Sex differences in the sensitization of prenatally programmed hypertension
Published 2025-04-01“…A more complete understanding of the functional capabilities of the sex hormones and their interactions with prohypertensive factors in offspring, from early life to aging, would likely lead to new insights into the basis of sex differences in programmed hypertension. …”
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9073
Key regulatory genes in sugar beet's defense against curly top virus identified by network analysis and qRT-PCR
Published 2025-09-01“…Network analysis identified nine central hub genes associated with fatty acid metabolism, stress adaptation, and transcriptional regulation. Meanwhile, functional enrichment analysis highlighted chloroplast-associated immune signaling, oxidative stress modulation, and secondary metabolite biosynthesis as critical defense mechanisms. …”
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9074
A cross-scale acoustic computational approach for micro-macro mode mapping to facilitate the development of high-performance underwater two-phase composites
Published 2025-07-01“…This investigation elucidates the microstructure-property coupling mechanism in polymeric systems, enabling precise control of macroscopic acoustic performance through microstructural parameter modulation. The established approach provides an alternative methodology with promising engineering applications for developing next-generation underwater acoustic functional materials.…”
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9075
Conserved stress-responsive genes involved in the early development of Euterpe Edulis
Published 2025-07-01“…Using eight RNA-Seq libraries, the strategy was to obtain the first transcriptome for the species through reference mapping against the Elaeis guineensis genome, with focus on conserved genes, followed by differential expression and functional annotation analyses. Among the 32,000 conserved genes identified, 1,133 were differentially expressed, with 11 showing differential expression in both tissues, 678 exclusively in leaves, and 444 in roots. …”
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9076
Revisiting the Thermal Behavior and Infrared Absorbance Bands of Anhydrous and Hydrated DL-Tartaric Acid
Published 2025-04-01“…In this work, we studied the thermal behavior and infrared fingerprint of anhydrous and hydrated DL-tartaric acid via conventional and modulated Differential Scanning Calorimetry (DSC), Thermogravimetry (TGA), Fourier Transform Infrared Spectroscopy (FTIR), nuclear magnetic resonance (NMR), pH measurements, and ab initio density functional theory (DFT) calculations. …”
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9077
Genetic background and oncogenic driver determines the genomic evolution and transcriptomics of mammary tumor metastasis
Published 2025-08-01“…Despite the diversity of MSCNV and MSGE, functional analysis revealed that both mechanisms converge on the modulation of key cellular processes, including immune responses, metabolism, and extracellular matrix interactions. …”
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9078
Biomimetic nanocomplexes loading with evolocumab and curcumin for synergistic anti-atherosclerosis therapy in ApoE−/− mice
Published 2025-06-01“…In this study, we developed a dual-functional nanodelivery system co-encapsulating PCSK9 inhibitor of evolocumab and natural anti-inflammatory agent of curcumin, with surface modification using macrophage membranes (Møm) and hyaluronic acid (HA). …”
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9079
The homeodomain transcription factor VvOCP3 negatively regulates white rot resistance in grape
Published 2025-09-01“…Expression analysis showed that VvOCP3 expression was significantly down-regulated upon inoculation with C. diplodiella. Functional analysis with transient injection in grape berries and stable overexpression in grape calli demonstrated that VvOCP3 negatively regulates grape resistance to C. diplodiella. …”
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9080
ATAD2 Overexpression Identifies Colorectal Cancer Patients with Poor Prognosis and Drives Proliferation of Cancer Cells
Published 2015-01-01“…ATPase family AAA domain-containing 2 (ATAD2) has been identified as a critical modulator involved in cell proliferation and invasion. …”
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