Tunable, permanent and instantly available super-wettability states on metal surfaces by laser texturing and plasma coating by Daniel Holder, Paul Reichle, Georg Umlauf, Rudolf Weber, Jakob Barz, Thomas Graf

“…The integration of laser texturing and PECVD coating provides a versatile and simple pathway for fabricating functional surfaces with tunable wettability and long-term performance across multiple metals and fluids.…”
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Combination of Sodium Butyrate and Immunotherapy in Glioma: regulation of immunologically hot and cold tumors via gut microbiota and metabolites by Sui Li, Sui Li, Li Wang, MingYu Han, Huali Fan, Hailin Tang, Huile Gao, Guobo Li, Zheng Xu, Zhaokai Zhou, JunRong Du, Cheng Peng, Fu Peng, Fu Peng

“…The gut microbiota, particularly its bacterial composition, plays a crucial role in the development and function of the immune system. Moreover, metabolites produced by the gut microbiota can significantly impact both systemic immune responses and central nervous system (CNS) immunity. …”
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Multi-omics approaches reveal the mechanisms underlying the interaction between cyst fluid of Echinococcus granulosus and host immune cells by Rongdong He, Rongdong He, Ruofeng Yan, Yuanchun Shi, Aili Aierken, Xue Zhang, Hao Wen, Hao Wen, Kalibixiati Aimulajiang

“…Th9 cells are a newly reported subpopulation of Th cells whose primary function is to secrete IL-9 and exert biological effects. …”
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Jingtian granule alleviates adenine-induced renal fibrosis in mice through SIRT3-Mediated deacetylation of P53 by Zhili Xiong, Zhili Xiong, Zhili Xiong, Zhili Xiong, Xinyu Hu, Rui Wang, Rui Wang, Rui Wang, Chengyin Li, Chengyin Li, Chengyin Li, Huanbo Cheng, Wei Zhao, Yinfeng Shen, Linqun Wang, Weinan Li, Weinan Li, Weinan Li, Xiaoyun Zhu, Yuanming Ba, Yuanming Ba, Yuanming Ba

“…Subsequently, under the premise of SIRT3 knockout, renal function, fibrosis level, iron metabolism level, and lipid peroxidation level were detected, and mitochondrial damage was observed by transmission electron microscope (TEM). …”
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Identification of novel inhibitors of dengue viral NS5 RNA-dependent RNA polymerase through molecular docking, biological activity evaluation and molecular dynamics simulations by Keli Zong, Chaochun Wei, Wei Li, Cong Wang, Jiajun Ruan, Xiaojing Liu, Susu Zhang, Hong Yan, Ruiyuan Cao, Xingzhou Li

“…The comprehensive MD simulations were performed on the candidates to assess the stability behaviour and binding mechanisms. The density functional theory (DFT) analysis was also conducted to explore the structural and electronic properties.…”
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Dynamic reconfiguration of brain coactivation states associated with active and lecture-based learning of university physics by Donisha D. Smith, Jessica E. Bartley, Julio A. Peraza, Katherine L. Bottenhorn, Jason S. Nomi, Lucina Q. Uddin, Michael C. Riedel, Taylor Salo, Robert W. Laird, Shannon M. Pruden, Matthew T. Sutherland, Eric Brewe, Angela R. Laird

“…Abstract Academic institutions are increasingly adopting active learning methods to enhance educational outcomes. Using functional magnetic resonance imaging (fMRI), we investigated neurobiological differences between active learning and traditional lecture-based approaches in university physics education. …”
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Alpha-synuclein interacts with regulators of ATP homeostasis in mitochondria by Tetiana Serdiuk, Yanick Fleischmann, Dhiman Ghosh, Aro Delparente, Viviane Reber, Larissa Frey, David Rhyner, Juan Gerez, Norbert Volkmar, Lucie Kralickova, Guillaume Mas, Christian Dörig, Sebastian Hiller, Roger Schibli, Linjing Mu, Paola Picotti, Roland Riek

“…NMR analysis demonstrates that both AK2 and DJ1 bind to the C-terminus and other segments of α-synuclein. Using a functional assay for AK2, we show that monomeric α-synuclein has an activating effect, whereas C-terminally truncated α-synuclein and α-synuclein in an amyloid fibrillar state have no significant effect on AK2 activity. …”
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Temporal single-cell sequencing analysis reveals that GPNMB-expressing macrophages potentiate muscle regeneration by Yu-Fan Chen, Chien-Wei Lee, Yi-Shuan J. Li, Wei-Ting Lin, Hsiao-Yun Chen, Yu-Chuan Chen, Chia-Hao Lin, Jennifer Hui-Chun Ho, Li-Fan Lu, Shu Chien, Oscar Kuang-Sheng Lee

“…Gpnmb gene knockout inhibited macrophage-mediated efferocytosis and impaired skeletal muscle regeneration. Functional studies demonstrated that GPNMB acts directly on muscle cells in vitro and improves muscle regeneration in vivo. …”
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Attenuation of skin injury by a MARCO targeting PLGA nanoparticle by Ummiye V. Onay, Dan Xu, Dauren Biyashev, Spencer T. Evans, Michael M. Demczuk, Tobias Neef, Joseph R. Podojil, Sara Beddow, Nathan C. Gianneschi, I. Caroline Le Poole, Stephen D. Miller, Kurt Q. Lu

“…Thus, in severe skin trauma, PLGA-IMPs may have therapeutic potential via modulation of inflammatory myeloid cells and regulatory T lymphocytes.…”
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Metabolite-driven mechanisms reveal chemical ecology of Lehmann Lovegrass (Eragrostis lehmanniana) invasion in North American semi-arid ecosystems by Ben Yang, Mekayla Crawford, Taylor A. Portman, Jeffrey S. Fehmi, Craig Rasmussen, David W. Hoyt, Jason Toyoda, Rosalie K. Chu, Chaevien S. Clendinen, Dušan Veličković, A. Elizabeth Arnold, Malak M. Tfaily

“…Abstract Invasive plants threaten global ecosystems, yet traditional analyses of functional traits cannot fully explain their dominance over co-occurring natives. …”
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ACCDW-YOLO: an effective detection method for small-sized pests and diseases in navel oranges by Kai Wang, Youliang Chen, Hanzheng Sun

“…The incorporation of the DCNv3 module into the design creates the DCNv3-E-ELAN module, which enhances the model’s proficiency in detecting objects of varying sizes. …”
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Location- and feature-based selection histories make independent, qualitatively distinct contributions to urgent visuomotor performance by Emily E Oor, Emilio Salinas, Terrence R Stanford

“…By imposing urgency, performance could be tracked continuously as it transitioned from uninformed guesses to informed choices as a function of processing time. This, in turn, permitted assessment of attentional control as manifest in motor biases, processing speed, and asymptotic accuracy. …”
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Scaffold Proteins in Fibrotic Diseases of Visceral Organs by Piaopiao Sun, Liliang Yang, Keqing Yu, Jing Wang, Jie Chao

“…Their pivotal role in linking mechanotransduction, inflammatory, and developmental signals offers a unique therapeutic window, as targeted interventions (e.g., small-molecule inhibitors, peptides, biologics, and gene therapy) are emerging to modulate these pathways. This review synthesizes recent findings on scaffold protein functions across multiple organs and discusses novel therapeutic strategies to manage and potentially reverse fibrosis.…”
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The role of oxytocin as an indicator of outcome and therapeutic alliance by Chiara Durante, Giulia Di Vincenzo, Alessandra Minutoli, Giampaolo Nicolais, Valeria Carola

“… Oxytocin is a neuropeptide produced by the hypothalamus and involved in numerous functions, such as labor and breastfeeding. The literature has highlighted the critical role of this hormone in interpersonal relationships – particularly in mother-child and sentimental relationships – implicating it in attachment bonds. …”
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Scalable Synthesis of PtAu Nanoalloy-Decorated Hydrogenated TiO₂ for High-Efficiency Indoor Formaldehyde Photodegradation by Hairui Cai, Benjamin Yang, Jie Hou, Ziqi Wang, Zhuo Li

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Myo-inositol increases respiratory burst, cellular proliferation, and phagocytosis of cultured leukocytes from Nile tilapia by Edgar Junio Damasceno Rodrigues, Pedro Luiz Pucci Figueiredo de Carvalho, Vitor Fernandes Silva, Delbert M. Gatlin, III, Margarida Maria Barros

“…Based on the results of all measured responses, 900 mg l-1 of MI was considered the optimal supplementation level for stimulating immunological functions of cultured Nile tilapia leukocytes. The findings of this study provided evidence of both the positive effects of MI and its role in modulating immunological responses of leukocytes highlighting MI potential as an immunomodulatory aquafeed additive.…”
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Epithelial zinc finger protein in lung adenocarcinoma: prognostic biomarker with molecular and clinical implications by Xiaofen Wen, Jianling Zhu, Didi Xi, Minna Chen, De Zeng, Wenwu Xue, Danxia Lin, Jiaxin Shen

“…The constructed nomogram exhibited strong predictive accuracy for patient outcomes. Conclusion EZF functions as a context-dependent regulator in LAC and may act as a prognostic biomarker by modulating tumor-immune interactions. …”
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NCAM and attached polysialic acid affect behaviors of breast epithelial cells through differential signaling pathways by Wu Yurong, Yang Juhong, Wang Xin, Guo Jia, Tan Zengqi, Guan Feng, Cao Lin

“…Polysialylated NCAM occurs in many types of cancer, but rarely in normal adult tissues. The functional role of NCAM hypersialylation in the epithelial-mesenchymal transition (EMT) process remains unclear. …”
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Tea Disease Detection Method Based on Improved YOLOv8 in Complex Background by Junchen Ai, Yadong Li, Shengxiang Gao, Rongsheng Hu, Wengang Che

“…The model introduces the SSPDConv convolution module in the backbone of YOLOv8 to enhance the global information perception of the model under complex backgrounds; a new ESPPFCSPC module is proposed to replace the original spatial pyramid pool SPPF module, which optimizes the multi-scale feature expression; and the MPDIoU loss function is introduced to optimize the problem that the original CIoU is insensitive to the change of target size, and the positioning ability of small targets is improved. …”
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Large-scale and long-distance distributed explosion sound wave test system by Wang Maokai, Lai Fuwen, Zhao Yongfeng, Kong Fansheng, Wang Wenlian

“…The system uses FPGA as the core controller and acquisition and storage of explosion sound wave signals is realized by using stored testing technology.Time synchronization as well as node positioning information in long-distance distributed measurement is achieved by the timing and positioning function of BeiDou satellite navigation system. On the other hand, linear spread spectrum modulation technology of LoRa is used to form a large-scaler distributed sensor network with long-distance and low power consumption. …”
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