Klebsiella oxytoca facilitates microbiome recovery via antibiotic degradation and restores colonization resistance in a diet-dependent manner by Éva d. H. Almási, Lea Eisenhard, Lisa Osbelt, Till Robin Lesker, Anna C. Vetter, Nele Knischewski, Agata Anna Bielecka, Achim Gronow, Uthayakumar Muthukumarasamy, Marie Wende, Caroline Tawk, Meina Neumann-Schaal, Mark Brönstrup, Till Strowig

“…Our findings provide insights into how diet modulates functional microbiome recovery and K. oxytoca-mediated pathogen elimination from the gut.…”
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The influence of surface rocking motion on the dynamic responses of drillstring during horizontal well drilling by Liu Yang, Chen Sitong, Wei Shuyong, Tao Haijun, Xiang Xingyun, Ma Tianshou

“…The frictional velocity dependence is described by the Dieterich-Ruina model and the discontinuous rocking motion is depicted by a trapezoidal wave function. The accuracy of the model is validated through scaled experiments and field data. …”
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DTCformer: A Temporal Convolution-Enhanced Autoformer with DILATE Loss for Photovoltaic Power Forecasting by Quanhui Qiu, Dejun Ning, Qiang Guo, Jiang Wei, Huichang Chen, Lihui Sui, Yi Liu, Zibing Du, Shipeng Liu

“…Furthermore, it incorporates the DILATE loss function, which significantly enhances both forecasting accuracy and robustness. …”
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Endothelial Plasticity: Shifting Phenotypes through Force Feedback by Guido Krenning, Valerio G. Barauna, José E. Krieger, Martin C. Harmsen, Jan-Renier A. J. Moonen

“…Hemodynamic forces such as fluid shear stress and cyclic strain are strong modulators of the endothelial phenotype and function. …”
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Pharmacological and Pathological Implications of Sigma-1 Receptor in Neurodegenerative Diseases by Noah Drewes, Xiangwei Fang, Nikhil Gupta, Daotai Nie

“…Over the past two decades, extensive research has revealed that the sigma-1 receptor regulates many cellular processes, such as calcium homeostasis, oxidative stress responses, protein folding, and mitochondrial function. The various functions of the sigma-1 receptor highlight its role as a central modulator of neuronal health and may be a promising pharmacological target across multiple neurodegenerative conditions. …”
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Fringe Texture Driven Droplet Measurement End-to-End Network Based on Physics Aberrations Restoration of Coherence Scanning Interferometry by Zhou Zhang, Jiankui Chen, Hua Yang, Zhouping Yin

“…Firstly, the 3D point spread function (PSF) for CSI imaging is modeling to relate the degradation and image. …”
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Improved UAV Target Detection Model for RT-DETR by Yong He, Yufan Pang, Guolin Ou, Renfeng Xiao, Yifan Tang

“…Furthermore, the Focaler-MPDIoU loss function has been developed to address the challenge of suboptimal localization accuracy for hard-to-detect targets and diminutive targets. …”
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Metabolic pathways associated with Firmicutes prevalence in the gut of multiple livestock animals and humans by Beatriz do Carmo Dias, Alessandra Pavan Lamarca, Douglas Terra Machado, Vinicius Prata Kloh, Fabíola Marques de Carvalho, Ana Tereza Ribeiro Vasconcelos

“…Firmicutes, one of the dominant bacterial phyla present across vertebrate classes, exhibits a wide range of functional capabilities and colonization strategies. …”
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Liberties of the genome: insertions of mitochondrial DNA fragments into nuclear genome by M. V. Golubenko, V. P. Puzyrev

“…In some cases, the insertion of multiple copies of the complete mitochondrial genome sequence may mimic paternal inheritance of mtDNA. The functional significance of NUMTS is poorly understood. …”
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LncRNA GTF3C1 promotes diabetic corneal wound healing by regulating GABARAP and PTEN to augment autophagy by Danling Liao, Wenqu Chen, Yuyang Deng, Shijia Wei, Li Wang, Jianzhang Hu

“…Methods High-throughput sequencing identified dysregulated lncRNAs in the trigeminal ganglia of diabetic mice. Functional validation included mechanistic studies on lncRNA GTF3C1, miR-542-3p, and autophagy-related targets. …”
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Ionic liquid-assisted biomass-derived N, S-doped carbon dots with enhanced corrosion inhibition by Shuyun Cao, Yang Zhao, Yubao Cao, Yongwei Li, Haodong Tan, Hong Wang

“…Both IL-CDs and CDs contained abundant N- and S-functional groups, endowing them with photoluminescence and distinct UV–Vis spectral features. …”
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Influence of stand age on sediment bacterial communities in restored mangrove forests by Jiayong Lai, Kishneth Palaniveloo, Sahadev Sharma, Rozainah Mohamad Zakaria, Wee Cheah

“…Co-occurrence network analysis revealed increasing module counts in younger restored mangrove forests, with stabilised counts observed at the 9 years suggesting established bacterial functional dynamics by this age. …”
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CD44 signaling in skin wound healing and regeneration by Annie Y. Guan, Yanlin Chen, Scheffer C. Tseng, Qing Lin

“…A better understanding of how to fine-tune CD44 signaling and identify its specific downstream effectors to modulate immune cell functions, inflammation, and regeneration will help shift the balance away from fibrotic scarring processes and open new therapeutic avenues for scarless regenerative wound healing. …”
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Mechanistic insights into CDCA gene family-mediated glioblastoma progression: implications for diagnosis, prognosis, and therapeutic targeting by Chang Liu

“…Additionally, CDCA gene expression was linked to immune modulation and cell cycle-related functions, suggesting their involvement in immune evasion and tumor proliferation. …”
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Activation-induced cytidine deaminase (AID)-associated multigene signature to assess impact of AID in etiology of diseases with inflammatory component. by Diana Mechtcheriakova, Yury Sobanov, Gabriele Holtappels, Erika Bajna, Martin Svoboda, Markus Jaritz, Claus Bachert, Erika Jensen-Jarolim

“…Activation-induced cytidine deaminase (AID) is expressed in B cells within germinal centers and is critically involved in class switch recombination and somatic hypermutation of immunoglobulin loci. Functionally active AID can additionally be detected within ectopic follicular structures developed at sites of chronic inflammation. …”
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Mariner Transposons Contain a Silencer: Possible Role of the Polycomb Repressive Complex 2. by Solenne Bire, Sophie Casteret, Benoît Piégu, Linda Beauclair, Nathalie Moiré, Peter Arensbuger, Yves Bigot

“…Here, we describe a silencer situated in the last 300 bp of the Mos1 transposase open reading frame (ORF) which functions in vertebrate and arthropod cells. Functional silencers are also found at similar locations within three other animal mariner elements, i.e. …”
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Research progress on the role of parathyroid hormone and parathyroid hormone-related peptide in regulating tooth eruption by LUO Qian, HU Yushang, YANG Kun, GE Song, ZHONG Wenyi

“…The emergence of teeth is a complex physiological process characterized by the formation of the tooth crown, its movement towards the occlusal plane, and subsequent penetration through the alveolar bone and oral mucosa to achieve functional positioning for contact with opposing teeth. …”
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Rspo3-mediated metabolic liver zonation regulates systemic glucose metabolism and body mass in mice. by Kenji Uno, Takuya Uchino, Takashi Suzuki, Yohei Sayama, Naoki Edo, Kiyoko Uno-Eder, Koji Morita, Toshio Ishikawa, Miho Koizumi, Hiroaki Honda, Hideki Katagiri, Kazuhisa Tsukamoto

“…In this study, we analyze the local functions of Rspo3 in the liver and the remote actions of hepatic Rspo3 on other organs of the body by using murine models. …”
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SaUGTs regulate YE-induced phytoalexins homeostasis in Sorbus aucuparia suspension cells by Wenjin Zhang, Xiaojia Zhang, Le Liang, Jian Yang, Lanping Guo

“…Nevertheless, the biological functions of GTs in Sorbus aucuparia remain largely unexplored. …”
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Tumor microenvironment responsive Mn-based nanoplatform activate cGAS-STING pathway combined with metabolic interference for enhanced anti-tumor therapy by E. Wen, Yu Tian, Yu Chen, Zhigang Wang, Yi Feng, Zhen Liao

“…Once internalized by cells, LT rapidly localizes to mitochondria via functional groups, disrupting mitochondrial metabolism and increasing intracellular reactive oxygen species levels. …”
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