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8801
Research and development prospects of TRIM65
Published 2025-08-01“…Abstract Ubiquitination, the prevalent posttranslational modification, plays a crucial role in regulating protein function, localization, and degradation within cellular environments. …”
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8802
Reduced component cascaded switched capacitor multilevel inverter for renewable energy applications
Published 2024-12-01“…For this purpose, a comprehensive comparison is performed by defining the cost function. The proposed topology under dynamic operating conditions is examined and validated. …”
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8803
Gastrointestinal health anti-diarrheal mixture relieves spleen deficiency-induced diarrhea through regulating gut microbiota
Published 2024-11-01“…It increased the abundance of beneficial bacteria, such as Romboutsia and Clostridium_sensu_stricto_1, and decreased the levels of diarrhea-associated bacteria, such as Prevotellaceae and Bacillus, thereby improving microbiota functionality. GHAM’s modulation of gut microbiota structure and function effectively alleviated spleen deficiency-induced diarrhea, positioning it as a potential natural herbal treatment for gastrointestinal ailments. …”
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8804
Experimental observation of nonreciprocal magnonic frequency combs
Published 2025-01-01“…This research promotes the combination of MFCs and functional non-Hermitian cavity-magnon electronic devices, realizing new applications for nonreciprocal magnonic devices.…”
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8805
Global research trends in Chinese medicine for the treatment of non-alcoholic fatty liver disease (NAFLD): A bibliometric study
Published 2025-03-01“…Antioxidant properties arise from bioactive compounds in TCM and their modulation of related pathways. Lipid metabolism improvement occurs through the regulation of spleen and stomach functions, promoting lipolysis. …”
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8806
Macrophage Signaling Pathways in Health and Disease: From Bench to Bedside Applications
Published 2025-07-01“…ABSTRACT Macrophages exhibit remarkable functional plasticity by dynamically polarizing into proinflammatory or antiinflammatory subsets in response to microenvironmental cues. …”
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8807
Genome-wide analysis of the KCS gene family in Medicago truncatula and their expression profile under various abiotic stress
Published 2025-05-01“…Abstract Very long-chain fatty acids (VLCFAs) are indispensable constituents of cuticular wax and exert pivotal functions in regulating plant growth, development and response to stress. β-Ketoacyl-CoA synthase (KCS) represents the rate-limiting enzyme for the biosynthesis of VLCFAs. …”
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8808
Exploring the Gut Microbiota–Retina Axis: Implications for Health and Disease
Published 2025-05-01“…The gut microbiota represents a rich and adaptive microbial network inhabiting the gastrointestinal tract, performing key functions in nutrient processing, immune response modulation, intestinal wall protection, and microbial defense. …”
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8809
Sirtuins and Gut Microbiota: Dynamics in Health and a Journey from Metabolic Dysfunction to Hepatocellular Carcinoma
Published 2025-03-01“…Recent findings indicate that sirtuins modulate gut microbiota composition and function, while the microbiota can affect sirtuin activity. …”
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8810
Mathematical Modeling for Ceramic Shape 3D Image Based on Deep Learning Algorithm
Published 2021-01-01“…In order to reduce the complexity of the model, a 3D contextual sequencing model is adopted to encode the hidden space features along the channel dimensions, to extract the causal correlation between channels. Each module in the compression framework is optimized by a rate-distortion loss function. …”
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8811
Ultraviolet Radiation-Induced Tolerogenic Dendritic Cells in Skin: Insights and Mechanisms
Published 2025-02-01“…Understanding the mechanisms by which UV radiation alters DC function offers insights into the complex interplay between environmental factors and immune regulation, providing potential avenues for preventive and therapeutic intervention in UV-induced skin diseases.…”
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8812
Acyclovir Therapy Reduces the CD4+ T Cell Response against the Immunodominant pp65 Protein from Cytomegalovirus in Immune Competent Individuals.
Published 2015-01-01“…These data show that low dose acyclovir treatment has the potential to modulate components of the T cell response to CMV antigen proteins and indicate that anti-viral drugs should be further investigated as a means to reduce the magnitude of CMV-specific immune response and potentially improve overall immune function.…”
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8813
Analyzing the Stability of a Connected Moving Cart on an Inclined Surface with a Damped Nonlinear Spring
Published 2024-08-01“…Secular terms have been eliminated to meet the solvability criteria, and every instance of resonance that arises is categorized, where two of them are examined concurrently. Therefore, the modulation equations are developed based on the representations of the unknown complex function in polar form. …”
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8814
Onkologie und Sport
Published 2014-11-01“…Profound hypotheses included the modulation of metabolic factors, immune function, pro- and anti-inflammatory processes, sex hormones, and DNA repair capacities and oxidative stress. …”
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8815
Using the MWC model to describe heterotropic interactions in hemoglobin.
Published 2017-01-01“…According to the MWC model, allosteric ligands exert their effect on protein function by modulating the quaternary conformational transition of the protein. …”
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8816
Compromised Rat Testicular Antioxidant Defence System by Hypothyroidism before Puberty
Published 2012-01-01“…Altered thyroid function during early stages of development is known to affect adversely testicular growth, physiology, and antioxidant defence status at adulthood. …”
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8817
BODE INDEX AND THE RISK OF OSTEOPOROTIC FRACTURES IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS
Published 2016-07-01“…The goal of the study: to define theoretic correlation between BODE index in men with chronic obstructive pulmonary disease (COPD) and risk of osteoporotic fractures assessed as per bone mineral density and FRAX integral rate.Materials and methods. 125 men suffering from COPD smoking for a long period of time (the smoker index of 240 and time of smoking (packs/years) of 40) were included into the study. 10 year risk of osteoporotic fractures was assessed by FRAX software. The respiratory function was evaluated by the multi-module unit of MasterLab/Jaeger type. …”
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8818
Developmental programming of tissue-resident macrophages
Published 2024-11-01“…In this review, we discuss the ontogeny of macrophages, the necessity of developmental programming by the niche for macrophage identity and function, and how developmental perturbations can affect the programming of macrophages and their subtissular niches, thereby influencing disease onset and progression in adulthood. …”
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8819
The association between Toxoplasma gondii infection and asthma in the United States: A cross-sectional survey analysis.
Published 2025-01-01“…Toxoplasma gondii is a common gastro-intestinal microorganism that may modulate immune function. We used a cross-sectional study design to examine a public database of U.S. residents aged 6-80 years or older from the 2012-2014 survey cycles of the American National Health and Nutrition Examination Survey (NHANES) to construct an ordinal logistic regression model of the relationship between T. gondii infection and asthma. …”
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8820
Structural design and experiment of automatic cooking machine
Published 2023-10-01“…<b>Methods:</b> The modular design method oriented to function and structure was adopted to design each module mechanism of the frying machine. …”
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