Isolation, Morpho-Molecular Characterization, Phylogenetics, and Pesticide Tolerance of Fructophilic Lactic Acid Bacteria from the Pollen, Honey, and Gut of Apis cerana indica Fabr... by Subramanian Pradeep, Y.S. Johnson Thangaraj Edward, Vangili Ramasamy Saminathan, Angappan Suganthi, Murugaiyan Senthilkumar, Narayanan Manikanda Boopathi

“…Future research should explore the functional mechanisms underlying pesticide detoxification and immune modulation to develop targeted probiotic formulations for sustainable apiculture.…”
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Identification and validation of diagnostic biomarkers for temporal lobe epilepsy related to ferroptosis and potential therapeutic targets by Dai Shi, Jingxuan Li, Zhenpeng Niu, Likun Wang, Siying Ren, Wen Gu, Hui Yang, Hong Xue, Guofeng Wu

“…A comprehensive analysis of the GSE134697 dataset from the Gene Expression Omnibus (GEO) database using Weighted gene co-expression network analysis (WGCNA) identified 3,212 differentially expressed genes (DEGs) between temporal lobe epilepsy (TLE) and control groups, with a critical focus on the turquoise module. Through intersection of DEGs and key module genes, correlation analyses with functional-related genes (FRG), protein-protein interactions (PPI), least absolute shrinkage and selection operator (LASSO), and machine learning methods, five potential biomarkers of ferroptosis (CBS, SHMT1, RIN3, QDPR, and PLPP4) were isolated. …”
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Structural basis for allosteric agonism of human α7 nicotinic acetylcholine receptors by Sanling Liu, Yining Zheng, Haopeng Chen, Xin Li, Qipeng Yan, Wenjun Mu, Yaning Fu, Huan Chen, Hongwei Hou, Lei Liu, Changlin Tian

“…Our results from both structural comparisons and functional assays suggest an allosteric mechanism underlying GAT107 modulation and calcium potentiation of α7 nAChR, involving local conformational changes in the ECD–TMD coupling region and a global structural rearrangement in the transmembrane domain. …”
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Synergistic combinations of Angelica sinensis for myocardial infarction treatment: network pharmacology and quadratic optimization approach by Wen-Di Wang, Xin-Yi Fan, Xiao-Qi Wei, Wang-Jing Chai, Fang-He Li, Kuo Gao, Bin Liu, Bin Liu, Shu-Zhen Guo

“…In vivo, Z-LIG/CGA significantly improved cardiac function and reduced the fibrotic area in mice post-MI, surpassing the results in groups treated with Z-LIG or CGA alone. …”
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Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage by Xue Li, Yao Zhuang, Ya Ru Zhang, Ke Ke Fan, Xin Xin Chen, Xin Xing Chen, Xuan Yi Liu, Jing Sun, Li Liu

“…Current research is limited to the individual application of dopamine D1 and D2 receptor-related agents, and the systematic effects of combined dopamine D1/D2 receptor inhibition on neural function remain unclear. In this study, we aimed to investigate the dose-dependent effects of co-DR1/2I (combined administration of dopamine receptor 1 inhibitor SCH39166 and dopamine receptor 2 inhibitor raclopride) on oxidative stress, learning, memory, emotion, and motor function in the substantia nigra, striatum, and hippocampus of mice.MethodsAfter administering varying doses of co-DR1/2I through gastric tubes to male C57BL/6 mice, we used enzyme-linked immunosorbent assay to measure monoamine oxidase B (MAO-B), reactive oxygen species (ROS), and superoxide dismutase (SOD) activity. …”
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Inhibition of microRNA-139-5p Improves Fibroblasts Viability and Enhances Wound Repair in Diabetic Rats Through AP-1 (c-Fos/c-Jun) by Mo J, Zhang J, Meng X, Wang F, Tang W, Liu Y, Fu L, Liang F, Mo Z

“…In vitro, the expression of microRNA-139-5p was up-regulated in human skin fibroblasts induced by high glucose treatment, while the function of the cell proliferation and migration was promoted and the level of AP-1 (c-Fos/c-Jun) was increased after transfected with the microRNA-139-5p inhibitor, and vice versa. …”
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ACLC-Detection: A Network for Remote Sensing Image Detection Based on Attention Mechanism and Lightweight Convolution by Shaodong Liu, Faming Shao, Chenshan Yang, Juying Dai, Jinhong Xue, Qing Liu, Tao Zhang

“…In addition, the C3k2 module in the neck fusion network part, where C3k = True, is replaced by the Convolutional Attention Module with Ghost Module (CAF-GM). …”
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The Development of a Lightweight DE-YOLO Model for Detecting Impurities and Broken Rice Grains by Zhenwei Liang, Xingyue Xu, Deyong Yang, Yanbin Liu

“…Firstly, changing the CBS module to the DBS module in the entire network model and replacing the standard convolution with Depthwise Separable Convolution (DSConv) can effectively reduce the number of parameters and the computational complexity, making the model lightweight. …”
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LPCF-YOLO: A YOLO-Based Lightweight Algorithm for Pedestrian Anomaly Detection with Parallel Cross-Fusion by Peiyi Jia, Hu Sheng, Shijie Jia

“…Furthermore, the Wise-IoU loss function is employed to enhance the model’s localization performance and generalization ability. …”
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Retracted: Study on Modeling Method of Forest Tree Image Recognition Based on CCD and Theodolite by Yeqiong Shi, Sainan Wang, Shuna Zhou, M. M. Kamruzzaman

“…The processing function has designed the interface of the image processing module. …”
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Adenosine Monophosphate-Activated Protein Kinase, Oxidative Stress, and Diabetic Endothelial Dysfunction by Ming-Hui Zou, Shengnan Wu, Tianyu Xu, Xiaoxia Fu.

“…Interestingly, oxidants-activated AMPK feedback lowers the levels of ROS by either suppressing ROS/RNS from reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and mitochondria or by increasing the levels of antioxidant enzymes (redox modulator). Further, our studies demonstrate that AMPK's functions as a redox sensor and modulator are vital to maintain endothelial cell function under physiological conditions. …”
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Distinct TAM subset with cross-dressing capability determines the bifurcation of tumor immunity by Kanako Shimizu, An Sanpei, Hiroshi Nakazato, Jun Shinga, Shogo Ueda, Yan Liu, Tomonori Iyoda, Satoru Yamasaki, Jun Nakabayashi, Shin-ichiro Fujii

“…Although several TAM subsets have been described, their functional roles remain unclear. In this study, we identified a distinct subset of CD9hiCD63hiCD206+Class IIlo hypoxic TAMs, located near tumors. …”
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Precision Radiotherapy: 18F-FDG PET-based radiotherapy planning in Head and Neck cancers by Padma Subramanyam, Shanmuga Palaniswamy, Shah Numani

“…Functional imaging such as Positron Emission Tomography (PET) has established its superiority over CT in delineating the actual site and extent of HN tumors. …”
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GSK3 acts as a switch for transcriptional programs in a model of low-grade gliomagenesis by Marilin S Koch, Minh Deo, Lena-Marie Schmitt, Michael S Hoetker, Şevin Turcan

“…Through the use of chemical compounds, we targeted WNT/GSK3, TGF-β and NOTCH-signaling, assessing their functional, transcriptional, and translational impacts. …”
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Ultrasound-Guided Percutaneous Nerve Stimulation in Post-Stroke Spasticity: A Case Report by Francesco Sartori, Albert Puig-Diví, Javier Picañol

“…Case description: A 38-year-old male with severe PSS and functional limitations post-ischemic stroke in the middle cerebral artery underwent a six-week pPNS protocol (12 sessions). …”
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A Hiplot‐based web service for cold atmospheric plasma high‐throughput data integration and analysis on breast cancer by Xiaofeng Dai, Mingjie Wang, Yang Liu

“…It can also interrogate the dynamic fluctuation, functional activity, and metabolic vulnerability of cancer cells in response to CAP by combinatorially analyzing omics at multiple carefully defined dimensions. …”
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Integrating bioinformatics and machine learning to discover sumoylation associated signatures in sepsis by Xue Teng, Qi Wang, Jinling Ma, Dongmei Li

“…Hub genes were defined as those exhibiting an area under the curve (AUC) greater than 0.7, significant gene expression, and a consistent trend. Localization and functional analyses of hub genes were conducted to enhance the understanding of these genes. …”
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Epitranscriptomic Control of Drought Tolerance in Rice: The Role of RNA Methylation by Xiaoru Fan, Yong Zhang, Pengyuan Gu, Misbah Naz

“…This review critically synthesizes current findings on the distribution and functional implications of m⁶A and other epitranscriptomic marks (e.g., 5-methylcytosine [m⁵C], <i>pseudouridine</i> [Ψ]) in modulating rice responses to drought. …”
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The effects of combined action of low-intensity electromagnetic radiation of the millimeter range and complexes of essential amino acids in tumor-bearing rats of old age by G. V. Zhukova, A. I. Shikhlyarova, L. N. Loginova, T. P. Protasova

“…We studied the dynamics of tumor size, adaptive status (according to hematological indicators of the character and tension of the general nonspecific adaptational reactions of the body), structural and functional changes in the tumor tissue, thymus and liver. …”
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Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis. by Elizabeth J Polvi, Anna F Averette, Soo Chan Lee, Taeyup Kim, Yong-Sun Bahn, Amanda O Veri, Nicole Robbins, Joseph Heitman, Leah E Cowen

“…Whole genome sequencing of mutants resistant to the combination of DTPA and caspofungin identified mutations in the histidine kinase gene NIK1 that confer resistance to the combination. Functional analyses demonstrated that DTPA activates the mitogen-activated protein kinase Hog1, and that NIK1 mutations block Hog1 activation in response to both caspofungin and DTPA. …”
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