Platelet-leukocyte interactions: immunoregulatory role and pathophysiological relevance by O. V. Pavlov, S. V. Chepanov, A. V. Selutin, S. A. Selkov

“…Chemokines, cytokines, growth factors, some of which are synthesized de novo, are released from activated platelets and modulate cellular functions, thus modulating both innate and adaptive immune response. …”
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NK cell activity in the tumor microenvironment by A. V. Kuznetsova, A. V. Kuznetsova, X. A. Glukhova, I. P. Beletsky, A. A. Ivanov

“…This review focusses on the biophysical characteristics of TME and specific components of the extracellular matrix (ECM) that affect NK cell activity, with the goal of identifying therapeutic approaches to modulate the TME and create a supportive niche for adaptive immune cell function. …”
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Intermittent fasting, fatty acid metabolism reprogramming, and neuroimmuno microenvironment: mechanisms and application prospects by Anren Zhang, Junyu Wang, Yinuo Zhao, Yu He, Nianyi Sun

“…IF not only facilitates fatty acid oxidation and improves metabolic health, but also enhances mitochondrial function, mitigates oxidative stress, promotes autophagy, and inhibits apoptosis and ferroptosis. …”
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Hepatoprotective Effect of Kaempferol—A Review by Przemysław Niziński, Anna Krajewska, Tomasz Oniszczuk, Beata Polak, Anna Oniszczuk

“…This substance activates the SIRT1/AMPK signalling pathway, improves mitochondrial function, inhibits proinflammatory cytokine production via TLR4/NF-κB suppression and attenuates hepatic stellate cell activation by modulating the TGF-β/Smad pathway. …”
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Harnessing exercise to combat chronic diseases: the role of Drp1-Mediated mitochondrial fission by Yingxin Sun, Junchen He, Junchen He, Lei Bao, Xiaoming Shi, Jinghong Wang, Qingwen Li

“…This, in turn, enhances mitochondrial function and cellular metabolism. This review synthesizes the current understanding of Drp1 structure and activation mechanisms, and analyzes the effects of exercise interventions on Drp1-mediated mitochondrial fission in different disease models to improve common chronic conditions. …”
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Adoptive transfer of natural killer cells in therapeutic treatment of COVID-19 patients by Abdulaziz Alamri

“…Their antiviral capabilities stem from direct cytotoxic activity against infected cells and immunoregulatory functions that modulate adaptive immune responses. …”
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The impact of pharmacological agents on neuroinflammation in neurodegenerative diseases by Sharma Anurag, Khan Zoya, Nath Rajendra, Dixit Rakesh Kumar

“…The review further highlights innovative pharmacologic strategies that modulate microglial function, moving beyond the outdated M1/M2 polarization models and embracing a more dynamic view of microglial plasticity, where activation depends on the local environment and disease context. …”
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Hollow Fiber Microreactor Combined with Digital Twin to Optimize the Antimicrobial Evaluation Process by Kazuhiro Noda, Toshihiro Kasama, Marie Shinohara, Masakaze Hamada, Yukiko T. Matsunaga, Madoka Takai, Yoshikazu Ishii, Ryo Miyake

“…By integrating functions of the HFIM, the extra-capillary space volume was reduced to less than 1/10 of conventional HFIM. …”
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LS-YOLO: A Lightweight, Real-Time YOLO-Based Target Detection Algorithm for Autonomous Driving Under Adverse Environmental Conditions by Cheng Ju, Yuxin Chang, Yuansha Xie, Dina Li

“…The LS-YOLO incorporates a MACA module to capture both global and local features, an SPDD module to reduce computational complexity, and a DR-Concat module to optimize feature fusion. …”
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Study on the vibration prediction model of step group hole blasting considering non-stationarity by LI Hongchao, ZHANG Qipeng, HUANG Guoquan, SHI Yulian, HUANG Yonghui, HAN Haoxuan, YI Jiaxin, QU Chenliang

“…The model expresses the frequency and intensity non-stationarity through modulated white noise and gamma function, and optimizes the parameters with residual similarity and orthogonal-pole difference analysis, finally realizing high accuracy prediction. …”
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3D-printed PCL scaffolds combined with injectable sodium alginate/magnesium-doped mesoporous bioactive glass nanosphere hydrogel for meniscus regeneration: In vitro, In vivo, and m... by Hao Li, Yongkang Yang, Tianze Gao, Runmeng Li, Chao Wang, Xue Wang, Tianyuan Zhao, Qinyu Tian, Zhixing Zhang, Ruiyang Zhang, Quanyi Guo, Zhiguo Yuan, Peifu Tang

“…Mechanistically, Mg-BGNs first activate the TRPM7 ion channel through the PI3K/AKT signaling pathway to promote the cellular function of synovium-derived mesenchymal stem cells and then activate the PPARγ/NF-κB axis to modulate macrophage polarization and inflammatory reactions. …”
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Secrecy Performance Analysis of Mixed <italic>&#x03B1;</italic> &#x2212; <italic>&#x03BC;</italic> and Exponentiated Weibull RF-FSO Cooperative Relaying System by Nazmul Hassan Juel, A. S. M. Badrudduza, S. M. Riazul Islam, Sheikh Habibul Islam, Milton Kumar Kundu, Imran Shafique Ansari, Md. Munjure Mowla, Kyung-Sup Kwak

“…Exploiting the amplify-and-forward (AF) relaying scheme while considering two detection techniques (i.e. heterodyne detection and intensity modulation/direct detection) with pointing error impairments, the mathematical formulations of the unified probability density function and cumulative distribution function are performed for the equivalent signal-to-noise ratio of the considered dual-hop RF-FSO link. …”
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Transcranial magnetic stimulation in the treatment of phantom limb pain: a systematic review by Gabriel Rocha Santos Knorst, Phamella Rocha de Souza, Armani Gontijo Plácido Di Araújo, Samantha Avanço Ferraz Knorst, Denise Sisterolli Diniz, Hélio Fernandes da Silva Filho

“…Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation method capable of influencing brain function and modulating cortical excitability. Its effectiveness in treating chronic pain is promising.…”
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Hematopoietic Stem Cell Mobilization and Homing after Transplantation: The Role of MMP-2, MMP-9, and MT1-MMP by Neeta Shirvaikar, Leah A. Marquez-Curtis, Anna Janowska-Wieczorek

“…Hematopoietic stem/progenitor cells (HSPCs) are used in clinical transplantation to restore hematopoietic function. Here we review the role of the soluble matrix metalloproteinases MMP-2 and MMP-9, and membrane type (MT)1-MMP in modulating processes critical to successful transplantation of HSPC, such as mobilization and homing. …”
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Method and System for Heart Rate Estimation Using Linear Prediction Filtering by Vitor O. T. Souza, Fabrício G. S. Silva, José M. Araújo, Jaimilton S. Lima

“…The proposal was validated with a Tektronix AFG1022 function generator that produces ECG signals and obtained measurements with accuracy above 98.87%, showing performance similar to studies presented in the literature. …”
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Research on the Method of Crop Pest and Disease Recognition Based on the Improved YOLOv7-U-Net Combined Network by Wenchao Xiang, Zitao Du, Xinran Liu, Zehui Lu, Yuna Yin

“…Experimental results show the improved algorithm achieves 97.49% detection accuracy, with mean average precision (mAP) reaching 96.91% and detection speed increasing to 90.41 FPS. The loss function of the improved U-Net network decreases towards 0 with training iterations, validating its effectiveness. …”
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Interferon Regulator Factor 8 (IRF8) Limits Ocular Pathology during HSV-1 Infection by Restraining the Activation and Expansion of CD8+ T Cells. by Lin Sun, Anthony J St Leger, Cheng-Rong Yu, Chang He, Rashid M Mahdi, Chi-Chao Chan, Hongsheng Wang, Herbert C Morse, Charles E Egwuagu

“…Although IRF8 expression is induced in activated T cells, the functional relevance of IRF8 in T cell-mediated immunity is not well understood. …”
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Rational Design of Covalent Organic Frameworks-Based Single Atom Catalysts for Oxygen Evolution Reaction and Oxygen Reduction Reaction by Wenli Xie, Bin Cui, Desheng Liu, Haicai Huang, Chuanlu Yang

“…Herein, the OER and ORR catalytic performance of a series of SACs based on TQBQ-COFs were systematically investigated through density functional theory (DFT) calculations, with particular emphasis on the role of the coordination environment in modulating catalytic activity. …”
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A comprehensive analysis of transcription factors identified TCF3 as a prognostic target for glioma by Qiao Li, Peng Feng, Shangyu Liu, Goupeng Tian, Guoqiang Yuan, Yawen Pan

“…Among these genes, TCF3 has emerged as a potential key prognostic marker because of its distinct expression patterns and functional relevance. By performing multi-omics and multi-dataset analyses, we explored the aberrant expression of TCF3 across multiple cancers, with robust validation at both the cellular and tissue levels. …”
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Long-term muscarinic inhibition increases intrinsic excitability through the upregulation of A-type potassium currents in cortical neurons by Denise Riquelme, Patricia Romo-Toledo, Paula Leyton, Claudio Moreno, Elias Leiva-Salcedo

“…Together, our work demonstrates that prolonged mAChR, but not nAChR, blockade induces structural and functional changes to compensate for the lack of mAChR signaling and to sustain a target level of electrical activity.…”
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