Human immune system: Exploring diversity across individuals and populations by Kim Han Hoang Nguyen, Nghi Vinh Le, Phuc Hoang Nguyen, Hien Hau Thi Nguyen, Duy Mai Hoang, Chien Dinh Huynh

“…The immune response is an intricate system that involves the complex connection of cellular and molecular components, each with distinct functional specialisations. It has a distinct capacity to adjust and mould the immune response in accordance with specific stimuli, influenced by both genetic and environmental factors. …”
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A review shows that ATG10 has been identified as a potential prognostic marker and therapeutic target for cancer patients based on real-world studies by Ke Shi, Di Ke, Feng Li, Rong-Shu Shi, Tao Liu, Dan Li, Qun-Xian Zhang

“…This review explores the functional and clinical significance of ATG10 across various cancers, highlighting its potential as a biomarker and therapeutic target.…”
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p63: A Master Regulator at the Crossroads Between Development, Senescence, Aging, and Cancer by Lakshana Sruthi Sadu Murari, Sam Kunkel, Anala Shetty, Addison Bents, Aayush Bhandary, Juan Carlos Rivera-Mulia

“…This review aims to elaborate on the diverse roles of p63, focusing on disease, development, and the mechanisms controlling genome organization and function.…”
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Unraveling the Role of the Microbiota in Cancer Immunotherapy: A New Frontier by Shouliang Wang, Shun Li, Mengli Zhang, Ruihan Liu, Xigang Ye, Siyi Mao, Jianwu Yu, Xinhua Xie, Weige Tan

“…Recent research has shown that the microbiota is crucial in shaping immune function and that its modulation can influence antitumor immunity. …”
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The role of deubiquitinases in cardiac disease by Xiaona Zhan, Yi Yang, Qing Li, Fan He

“…This review summarizes the function of different deubiquitinases in cardiac disease, including cardiac hypertrophy, myocardial infarction and diabetes mellitus-related cardiac disease. …”
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Latent EBV enhances the efficacy of anti-CD3 mAb in Type 1 diabetes by Ana Lledó-Delgado, Paula Preston-Hurlburt, Lauren Higdon, Alex Hu, Eddie James, Noha Lim, S. Alice Long, James McNamara, Hai Nguyen, Elisavet Serti, Tomokazu S. Sumida, Kevan C. Herold

“…Mechanistically, single cell transcriptomics and functional assays identify the downregulation of NFκB and T cell activation pathways after treatment in EBV-seropositive patients; among diabetes antigen-specific CD8+ T cells, T cell receptor and mTOR signaling are also reduced. …”
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Research summary, possible mechanisms and perspectives of gut microbiota changes causing precocious puberty by Maorong Bao, Rui Wu, Jingwei Li, Runan Tang, Cui Song

“…This review delineates taxonomic alterations in central precocious puberty (CPP) and obesity-related subtypes, including Streptococcus enrichment and Alistipes depletion, alongside functional shifts in microbial metabolite production. …”
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Stem Cell-Derived Extracellular Vesicles as Immunomodulatory Therapeutics by Yoojin Seo, Hyung-Sik Kim, In-Sun Hong

“…Mesenchymal stem cells (MSCs) have been reported to possess regulatory functions on immune cells which make them alternative therapeutics for the treatment of inflammatory and autoimmune diseases. …”
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Decoding innate lymphoid cells and innate-like lymphocytes in asthma: pathways to mechanisms and therapies by Christina Li-Ping Thio, Jheng-Syuan Shao, Chia-Hui Luo, Ya-Jen Chang

“…Regulatory mechanisms, including cytokine signaling, metabolic and dietary cues, and interactions with other immune cells, play critical roles in modulating their functions. In this review, we highlight current findings on the role of ILCs and innate-like lymphocytes in asthma development and pathogenesis. …”
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Influence of Dendritic Cells on B-Cell Responses during HIV Infection by Johanne Poudrier, Josiane Chagnon-Choquet, Michel Roger

“…DC populations have been reported to be affected in number, phenotype and function during HIV infection and such alterations may contribute to the dysregulation of the B-cell compartment. …”
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Observations on Rotating Instabilities and Spike Type Stall Inception in a High-Speed Multistage Compressor by Johannes Schreiber, Benoit Paoletti, Xavier Ottavy

“…Two different types of instabilities arise in this compressor as a function of shaft speed. At part speed, a controversy called “rotating instability” type flow field modulation is identified with the measurements. …”
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Differential and directional estrogenic signaling pathways induced by enterolignans and their precursors. by Yun Zhu, Kayoko Kawaguchi, Ryoiti Kiyama

“…We hypothesized that, while estrogen signaling is initiated by the enterolignans/precursors examined, their signals are differentially and directionally modulated later in the pathways, resulting in the differences at the cell function level.…”
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Indole metabolism and its role in diabetic macrovascular and microvascular complications by W. Hu, C. Garrison, R. Prasad, M.E. Boulton, M.B. Grant

“…Trp metabolites extend their influence beyond protein biosynthesis to affect a spectrum of pathophysiological mechanisms including, but not limited to, neuronal function, immune modulation, inflammatory responses, oxidative stress regulation, and maintenance of intestinal health. …”
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Study on Optimal Decision of Unit Commitment with Flexible Reserve Participation in Power Grid by ZHOU Yi, LI Yichen, FU Youshu, QIN Kangping, ZHU Wen, FAN Dongqi

“…New energy frequency modulation, DC modulation and interruptible load are classified as grid flexible reserve, and the reserve potential is quantified. …”
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Detection method of potato leaf disease based on YOLOv5s by Jingtao Li, Hao Chen, Guisong Li, Yueqi Liu, Yanli Yang, Xia Liu, Chang Yi Wang

“…Secondly, CBAM attention module is introduced into the convolutional module to enhance local feature extraction and fusion capability of the network, while WIoU_Loss serves as Bounding box loss function SRN-DeblurNet deblurnet is combined with YOLOv5s network to convert part of fuzzy images into clear ones before being integrated with multi-scale features for model prediction. …”
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The Role of Exercise on Glial Cell Activity in Neuropathic Pain Management by Willians Fernando Vieira, Caroline C. Real, Daniel Oliveira Martins, Marucia Chacur

“…Exercise not only improves overall health and quality of life but also influences the function of GCs. Recent research highlights the ability of exercise to mitigate neuroinflammatory responses and modulate the activity of GCs by reducing the activation of microglia and astrocytes, as well as modulating the expression biomarkers, thereby attenuating pain hypersensitivity. …”
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Saccharomyces boulardii (CNCM I-745) improves intestinal damage in sepsis by remodeling intestinal flora structure by Hui-Ying Liu, Yao Li, Yi-Lu Lin, Yu-Jia Tang, Jin-Da Zhao, Jia Xu, Kuo Wang, Ying-Fei Zhi, Yan Zhang, Jia-Le Deng, Kai Kang, Ying Chen, Yang Gao

“…Moreover, the composition of the gut microbiota underwent a discernible alteration.ConclusionSepsis induces impairment of intestinal barrier function and exacerbates inflammatory responses. The use of S. boulardii (CNCM I-745) can modulate the composition of the intestinal flora by enhancing the colonization of beneficial bacteria while reducing the presence of harmful bacteria. …”
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CYP1B1 Knockout in a Bovine Hepatocyte-like Cell Line (BFH12) Unveils Its Role in Liver Homeostasis and Aflatoxin B1-Induced Hepatotoxicity by Silvia Iori, Ludovica Montanucci, Caterina D’Onofrio, Maija Lahtela-Kakkonen, Lorena Lucatello, Anisa Bardhi, Andrea Barbarossa, Francesca Capolongo, Anna Zaghini, Marianna Pauletto, Mauro Dacasto, Mery Giantin

“…These findings provide novel insights into <i>CYP1B1</i>’s function in bovine hepatocytes, highlighting its dual role in maintaining liver homeostasis and mediating AFB1 metabolism. …”
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IL-10: A Multifunctional Cytokine in Viral Infections by José M. Rojas, Miguel Avia, Verónica Martín, Noemí Sevilla

“…IL-10 can be produced by virtually all immune cells, and it can also modulate the function of these cells. Understanding the effects of this multifunctional cytokine is therefore a complex task. …”
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The Immunologic Role of Gut Microbiota in Patients with Chronic HBV Infection by Ruilin Yang, Yao Xu, Zhifeng Dai, Xuhong Lin, Huichao Wang

“…However, the gut and liver have the same embryonic origin; therefore, a close relationship must exist in terms of anatomy and function, and the gut microbiota plays an important role in host metabolic and immune modulation. …”
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