The Effects of Short-Chain Fatty Acids in Urological Diseases by Hee Jo Yang, Doo Sang Kim

“…The gut microbiota supports the digestion and absorption of food, metabolizes fiber into bioactive short-chain fatty acids (SCFA), produces vitamins and nutrients, maintains gut integrity, and modulates host immunity. Among the above, there has been great interest in SCFA in microbiome research due to its beneficial effects on the intestinal barrier function and systemic anti-inflammatory effects. …”
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Novel Human Embryonic Stem Cell Regulators Identified by Conserved and Distinct CpG Island Methylation State. by Steve Pells, Eirini Koutsouraki, Sofia Morfopoulou, Sara Valencia-Cadavid, Simon R Tomlinson, Ravi Kalathur, Matthias E Futschik, Paul A De Sousa

“…Human embryonic stem cells (hESCs) undergo epigenetic changes in vitro which may compromise function, so an epigenetic pluripotency "signature" would be invaluable for line validation. …”
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Attention-Guided Deep Reinforcement Learning for Realistic Neural Painting by Xin Huang, Minglun Gong

“…Specifically, the attention module computes an attention map to guide stroke generation, and a feature-masked reward function prioritizes important regions. …”
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Rab21 recruits EEA1 and competes with Rab5 for Rabex-5 activation by Francisco Yanguas, Cinzia Progida

“…Overexpression of Rab21 rescues the defects in EEA1 localization and endosomal size caused by the depletion of PI3P or the inhibition of Rab5 function, both needed for the recruitment of EEA1 to early endosomes. …”
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Illustration image style transfer method design based on improved cyclic consistent adversarial network. by Xiaojun Wang, Jing Jiang

“…The results show that when running on the Monet2photo dataset, when the system iterates to 72 times, the loss function value of the research method approaches the target value of 0.00. …”
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Mathematical and Physical Analysis of the Fractional Dynamical Model by Mohammed Ahmed Alomair, Haitham Qawaqneh

“…Through the application of the modified extended tanh function technique and the modified <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>(</mo><msup><mi>G</mi><mo>′</mo></msup><mo>/</mo><msup><mi>G</mi><mn>2</mn></msup><mo>)</mo></mrow></semantics></math></inline-formula>-expansion technique, we are able to achieve the series of exact solitons. …”
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Target Detection and Image Enhancement for Underwater Environment: Research on Improving YOLOv7 by Yang Luo, Wen Feng

“…In addition, by introducing the Focal-EIoU loss function, combined with a more accurate penalty mechanism, the matching between the predicted frame and the actual labelled frame is made more accurate, which effectively improves the accuracy and reliability of detection. …”
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Cerebroventricular microinjection (CVMI) into adult zebrafish brain is an efficient misexpression method for forebrain ventricular cells. by Caghan Kizil, Michael Brand

“…We also provide data on the use of CVMI for growth factor administration to the brain--in our case FGF8, which modulates the proliferation rate of the ventricular cells. …”
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Retromer regulates HIV-1 envelope glycoprotein trafficking and incorporation into virions. by Elisabetta Groppelli, Alice C Len, Luke A Granger, Clare Jolly

“…Consistent with this function, inactivating retromer using RNAi targeting the cargo selective trimer complex inhibited retrograde trafficking of endocytosed Env to the Golgi. …”
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Long non-coding RNA SPRY4-IT1 promotes proliferation and invasion by acting as a ceRNA of miR-101-3p in colorectal cancer cells by Jianguang Jin, Zhijie Chu, Pengfei Ma, Yuanpu Meng, Yanhui Yang

“…The aim of this study is to evaluate the expression and function of SPRY4-IT1 in colorectal carcinoma. In this study, we analyzed SPRY4-IT1 expression levels in a series of colorectal carcinoma patients by quantitative reverse transcription polymerase chain reaction. …”
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Gut microbiota and alcohol use disorder: a new frontier in treatment and recovery by Valentin Skryabin

“…Chronic alcohol consumption induces gut dysbiosis, characterised by reduced microbial diversity, impaired gut barrier function and systemic inflammation, which perpetuate neuroinflammation, stress dysregulation and neurotransmitter imbalances. …”
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ΔNp63 regulates Sfrp1 expression to direct salivary gland branching morphogenesis. by Theresa Wrynn, Sangwon Min, Erich Horeth, Jason Osinski, Satrajit Sinha, Rose-Anne Romano

“…Here, we performed in vivo and ex vivo studies of the embryonic mouse submandibular gland to determine the function of the transcription factor ΔNp63, in directing branching morphogenesis. …”
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Physical activity and glioblastoma: a paradigm shift in neuro-oncology therapy by Lin Xie, Feng Wang

“…Clinical and preclinical evidence suggests that exercise may improve cognitive function, reduce treatment-related toxicity, and prolong survival in GBM patients. …”
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Emerging role of the itaconate-mediated rescue of cellular metabolic stress by Der-Shan Sun, Hsin-Hou Chang

“…Evidence have suggested that ATF3 and nuclear factor erythroid 2–related factor 2 (NRF2) are critical for maintaining cell function, metabolism, and inflammation/anti-inflammation regulations when cells are under stress, while the upstream regulators in the stressed cells remain elusive. …”
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Polyphenols and post-exercise muscle damage: a comprehensive review of literature by Xiaofeng Zhang, Yuanfu Zhong, Sogand Rajabi

“…These protective effects are facilitated through several mechanisms, including the modulation of inflammatory pathways, acceleration of muscle repair processes, and enhancement of mitochondrial function, all of which bolster overall muscle health. …”
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Multiband adjustment engineering strategy for broadband range in photonic crystals by Wenjia Yu, Shiyu Liu, Hang Sun, Jicheng Wang, Yuting Yang, Xiaopeng Shen

“…Topological edge states are crucial for optical modulation, and the overlapping Brillouin zones in nested structures can effectively control multiband edge states. …”
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Synergy-Dependent Center-of-Mass Control Strategies During Sit-to-Stand Movements by Simone Ranaldi, Leonardo Gizzi, Giacomo Severini, Cristiano De Marchis

“…The characterization, through the concept of muscle synergies, of clinical functional tests is a valid tool that has been widely adopted in the research field. …”
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Advanced stress imaging in periodically strained, suspended, quasi-2D membranes: Manifestation of Fano resonance and phonon dynamics insights by Souvik Bhattacharjee, Biswajit Das, Anibrata Banerjee, Kalyan Kumar Chattopadhyay

“…The theoretical foundation is derived from density functional theory (DFT)-based calculations on phonon dispersion, Raman spectra, and associated thermodynamic attributes for layer-specific graphene against varying biaxial tensile stress. …”
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Harnessing the therapeutic value of Tanshinone IIA: a breakthrough therapy in cardiovascular diseases by Lanxiang Du, Chengyan Guan, Hao Zhang, Haoyue Jia, Qiang Wan, Qiang Wan

“…The therapeutic efficacy is mediated through multiple mechanisms, including but not limited to anti-atherosclerotic effects, lipid homeostasis regulation, anti-arrhythmic properties, myocardial functional enhancement, and hemodynamic stabilization. …”
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Learning-induced remodelling of inhibitory synapses in the motor cortex by Nishita Bhembre, Annalisa Paolino, Sooraj S. Das, Sumasri Guntupalli, Laura R. Fenlon, Victor Anggono

“…Robust structural and functional plasticity occurs at excitatory synapses in the motor cortex in response to learning. …”
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