-
8441
Role of Cav1.3 Channels in Brain–Heart Interactions: An Unexpected Journey
Published 2025-06-01“…This review aims to delve into the under-explored role of Cav1.3 in brain–heart interaction, specifically examining how it modulates ANS activity and, consequently, the cardiac function. …”
Get full text
Article -
8442
YOLO-CBD: Classroom Behavior Detection Method Based on Behavior Feature Extraction and Aggregation
Published 2025-05-01“…Finally, the Wise-IoU loss function is incorporated to handle sample imbalance issues. …”
Get full text
Article -
8443
A Study of Resolution Improvement in Noncoherent Optical Coherence Imaging
Published 2022-01-01“…Using a spatial light modulator (SLM) loaded with a bit-phase mask with multiplexed lens function, the incident light wavefield is phase-modulated to achieve diffraction spectroscopy and phase shifting. …”
Get full text
Article -
8444
Predicting the Behavior of Road Users in Rural Areas for Self-Driving Cars
Published 2023-07-01“…As a solution, we propose to use a neural network that includes the following submodules: a graph-based scene encoder, a multimodal trajectory decoder, and a trajectory filtering module. Another proposed feature is to use an adapted loss function that penalizes the network for generating trajectories that go beyond the drivable area. …”
Get full text
Article -
8445
-
8446
VPS4B orchestrates response to nuclear envelope stress by regulating ESCRT-III dynamics in glioblastoma
Published 2024-12-01“…Here, we found that VPS4B expression was lower in U251MG than in U87MG. Our functional analysis demonstrated that insufficient VPS4B triggers an inadequate response to NE stress and that VPS4B regulates the dynamics of ESCRT-III, uncovering the mechanism underlying the NE stress response in GBM.…”
Get full text
Article -
8447
Prevalence of transcription promoters within archaeal operons and coding sequences
Published 2009-06-01“…A significant fraction of these alternate transcriptional events correlate to binding locations of 11 transcription factors and regulators (TFs) inside operons and annotated genes—events usually considered spurious or non‐functional. Using experimental validation, we illustrate the prevalence of overlapping genomic signals in archaeal transcription, casting doubt on the general perception of rigid boundaries between coding sequences and regulatory elements.…”
Get full text
Article -
8448
Role and regulatory mechanism of GPR37 in neurological diseases
Published 2025-07-01“…This review summarizes current advances in the structural and functional understanding of GPR37, including its genomic localization, receptor architecture, endogenous ligands, and downstream signaling pathways. …”
Get full text
Article -
8449
Effects of fluorine modification on the photocatalytic hydrogen production performance of TiO2
Published 2025-06-01“…Surface fluorine adsorption or lattice fluorine doping can deftly modulate the surface chemical attributes and electronic configuration of the TiO2 photocatalyst, thereby amplifying its functional performance. …”
Get full text
Article -
8450
Restoring calcium crosstalk between ER and mitochondria promotes intestinal stem cell rejuvenation through autophagy in aged Drosophila
Published 2025-05-01“…Here, we show that genetically restoring MitoCa2+ can reverse ISC functional decline and promote intestinal homeostasis by activating autophagy in aged flies. …”
Get full text
Article -
8451
Probing amplified Josephson plasmons in YBa2Cu3O6+x by multidimensional spectroscopy
Published 2025-06-01“…Abstract The nonlinear driving of collective modes in quantum materials can lead to a number of striking non-equilibrium functional responses, which merit a comprehensive exploration of underlying dynamics. …”
Get full text
Article -
8452
Modular assembly of self-healing flexible thermoelectric devices with integrated cooling and heating capabilities
Published 2025-05-01“…Yet, current devices lack functional module expansion, which limits the customization for diverse energy-harvesting heat sources and complicates their assembly to meet the specific power requirements of electrical appliances. …”
Get full text
Article -
8453
Repurposing FDA-Approved Agents to Develop a Prototype <i>Helicobacter pylori</i> Shikimate Kinase (HPSK) Inhibitor: A Computational Approach Using Virtual Screening, MM-GBSA Calcu...
Published 2025-01-01“…Additionally, Density Functional Theory (DFT) analysis was conducted, and the Highest Occupied Molecular Orbitals (HOMOs), Lowest Unoccupied Molecular Orbitals (LUMOs), and the energy gap (HLG) between them were calculated. …”
Get full text
Article -
8454
Diagnostic and therapeutic role of non-coding RNAs regulating programmed cell death in melanoma
Published 2024-12-01“…Moreover, non-coding RNAs have the ability to modulate tumor cell autophagy, pyroptosis, and ferroptosis at the transcriptional or post-transcriptional stage, as well as function as oncogenes and tumor suppressor genes, which can have considerable effects on the incidence and growth of tumors. …”
Get full text
Article -
8455
Involvement of Norepinephrine in the Control of Activity and Attentive Processes in Animal Models of Attention Deficit Hyperactivity Disorder
Published 2004-01-01“…Functional and morphological studies in children affected by Attention Deficit Hyperactivity Disorder (ADHD) suggest a prefrontal cortex (PFc) dysfunction. …”
Get full text
Article -
8456
Dynamic Path Planning of Unknown Environment Based on Deep Reinforcement Learning
Published 2018-01-01“…The reward and punishment function and the training method are designed for the instability of the training stage and the sparsity of the environment state space. …”
Get full text
Article -
8457
Sox2-overexpressing neural stem cells alleviate ventricular enlargement and neurological dysfunction in posthemorrhagic hydrocephalus
Published 2026-02-01“…The results showed that NSCSox2 attenuated the ventricular enlargement caused by posthemorrhagic hydrocephalus and improved neurological function. NSCSox2 also promoted nerve regeneration, inhibited neuroinflammation and promoted M2 polarization (anti-inflammatory phenotype), thereby reducing cerebrospinal fluid secretion in choroid plexus. …”
Get full text
Article -
8458
Space-Time-Frequency Adaptive Processor for Multiple Interference Suppression in GNSS Applications
Published 2018-01-01“…Firstly, based on the analysis of the autocorrelation function of the multicomponent signal, we propose a common period estimation and data block technique to segment the received signal data into blocks. …”
Get full text
Article -
8459
Nanocurcumin in myocardial infarction therapy: emerging trends and future directions
Published 2025-01-01“…Curcumin nanoparticles have been observed to successfully reduce infarct size, maintain heart function by modulating essential molecular pathways in MI. …”
Get full text
Article -
8460
LTE Signal Transmission Over a Linearized Analog Photonic Link With High Fidelity
Published 2019-01-01“…The third-order intermodulation (IMD3) attributed to the MZM transfer function is suppressed by asymmetric RF and optical feeding that impose a <italic>π</italic>-phase difference between the signals in the two MZM channels. …”
Get full text
Article