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8401
Droplet Trajectory Movement Modeling Using a Drop-on-Demand Inkjet Printhead Simulations
Published 2025-01-01“…By considering the dynamics of a droplet surrounded by air, we modeled them using the two-phase flow coupling and level set function from the computational fluid dynamics module by COMSOL Multiphysics. …”
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8402
Helminths: Immunoregulation and Inflammatory Diseases—Which Side Are Trichinella spp. and Toxocara spp. on?
Published 2013-01-01“…Molecular crosstalk between the host and the parasite starts immediately after their encounter, which influences the course and development of both the innate and adaptive arms of the immune response. Helminths can modulate dendritic cells (DCs) function and induce immunosuppression which is mediated by a regulatory network that includes regulatory T (Treg) cells, regulatory B (Breg) cells, and alternatively activated macrophages (AAMs). …”
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8403
The microtubule-severing enzyme spastin regulates spindle dynamics to promote chromosome segregation in Trypanosoma brucei
Published 2025-07-01“…We further show that the function of spastin requires the catalytic AAA-ATPase domain, the microtubule-binding domain, and the microtubule interacting and trafficking domain, and that the association of spastin with spindle depends on the microtubule-binding domain. …”
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8404
An Annulus-Sector Segmented Primary Mirror
Published 2017-01-01“…Experimental results show that modulation transfer function of annulus-sector segment optical system can be up to 0.23(50 lp/mm), which approaches the optical resolution of full aperture optical system with smaller size and lighter weight.…”
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8405
Longevity pathways and maintenance of the proteome: the role of autophagy and mitophagy during yeast ageing
Published 2014-04-01“…Ageing is a complex and multi-factorial process that results in the progressive accumulation of molecular alterations that disrupt different cellular functions. The budding yeast Saccharomyces cerevisiae is an important model organism that has significantly contributed to the identification of conserved molecular and cellular determinants of ageing. …”
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8406
Parameter Extraction for Photovoltaic Models with Flood-Algorithm-Based Optimization
Published 2024-12-01“…This study explores two distinct objective functions to enhance accuracy: one based on experimental current–voltage data and another integrating the Newton–Raphson method. …”
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8407
Regulation of sharp wave-ripples by cholecystokinin-expressing interneurons and parvalbumin-expressing basket cells in the hippocampal CA3 region
Published 2025-05-01“…The results emphasize the crucial role of inhibitory interneurons in maintaining normal hippocampal oscillations, which are essential for proper brain function, particularly in the domains of memory consolidation and cognitive processes.…”
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8408
Epigenetic regulatory protein chromobox family regulates multiple signalling pathways and mechanisms in cancer
Published 2025-03-01“…The Chromobox (CBX) family proteins, which serve as significant epigenetic regulators, exhibit tumour-specific expression patterns and biological functionalities. These proteins are influenced by a multitude of factors and could modulate the activation of diverse signalling pathways within tumour cells through alterations in epigenetic modifications, thereby acting as either oncogenic agents or tumour suppressors. …”
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8409
SLC10A3 regulates ferroptosis of glioblastoma through the STAT3/GPX4 pathway
Published 2025-07-01“…In this research, bioinformatics revealed that SLC10A3 is upregulated in GBM and correlates with poor patient prognosis. Functional analysis showed that SLC10A3 regulates GBM growth and progression through ferroptosis and that silencing SLC10A3 enhances sensitivity to the ferroptosis inducer Erastin. …”
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8410
Whole Genome Sequence of the gut commensal protist Tritrichomonas musculus isolated from laboratory mice
Published 2025-04-01“…Parasite colonization reshapes the gut microbiome and modulates mucosal immunity. This parasite is refractory to axenic culture. …”
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8411
Tissue Regeneration without Stem Cell Transplantation: Self-Healing Potential from Ancestral Chemistry and Physical Energies
Published 2018-01-01“…To recover the damaged tissues and regenerate functional organs, scientific research in the field of regenerative medicine is firmly trying to understand the molecular mechanisms through which the regenerative potential of stem cells may be unfolded into a clinical application. …”
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8412
Parameters of Reserpine Analogs That Induce MSH2/MSH6-Dependent Cytotoxic Response
Published 2010-01-01“…Mismatch repair proteins modulate the cytotoxicity of several chemotherapeutic agents. …”
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8413
Microbiota and iron metabolism
Published 2025-08-01“…Both iron deficiency and iron overload in the gut can negatively affect the composition and function of the intestinal microbiota. Conversely, beneficial members of the colonic microbiota play a key role in enhancing systemic iron absorption. …”
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8414
Human neural organoid microphysiological systems show the building blocks necessary for basic learning and memory
Published 2025-08-01“…Neural organoids showed synapse formation, glutamatergic and GABAergic receptor expression, immediate early gene expression basally and evoked, functional connectivity, criticality, and synaptic plasticity in response to theta-burst stimulation. …”
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8415
Ultrastrong Graphene Absorption Induced by One-Dimensional Parity-Time Symmetric Photonic Crystal
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8416
Exploration of the Dual Role of Dectin-1 in Tumor Development and Its Therapeutic Potential
Published 2024-11-01“…Dectin-1, a C-type lectin receptor primarily involved in antifungal immunity, has emerged as a significant player in cancer biology, exhibiting both pro-tumor and anti-tumor roles. This dual function largely depends on the tumor type and microenvironment. …”
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8417
Stress, Inflammation and the Irritable Bowel Syndrome
Published 1999-01-01“…Studies in animals have shown that inflammation of the mucosa of the gastrointestinal tract is accompanied by changes in enteric nerve and smooth muscle function, and in gut motility and sensation. In some instances, these changes persist long after resolution of the mucosal inflammation. …”
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8418
Release of adenosine from human neutrophils stimulated by platelet activating factor, leukotriene B4 and opsonized zymosan
Published 1992-01-01“…These resuits suggest that adenosine, when bound specifically to membrane receptor sites, may initiate signal transduction, and, in co-operation with other inflammatory mediators, may modulate phagocyte function, e.g. production of chemoluminescence (CL).…”
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8419
Megavoltage X-Ray Imaging Based on Cerenkov Effect: A New Application of Optical Fibres to Radiation Therapy
Published 2012-01-01“…Properties, such as modulation transfer function, detection quantum efficiency (DQE), and energy response of the detector, were investigated. …”
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8420
Molecular Mechanisms of Action of Undenatured Type II Collagen: Experimental and Clinical Evidence
Published 2022-10-01“…The use of UDC-II in OA leads to a significant reduction in pain, an increase in the range of joint motion, an improvement in joint function according to WOMAC and quality of life.…”
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