Neurophysiological Markers of Reward Processing Can Inform Preclinical Neurorehabilitation Approaches for Cognitive Impairments Following Brain Injury by Miranda Francoeur Koloski, Reyana Menon, Victoria Krasnyanskiy

“…Neuromodulation applied with anatomical specificity can ameliorate desired symptoms while leaving functional circuits intact. Before applying precision medicine approaches, preclinical animal studies are needed to explore potential neurophysiological signatures that could be modulated with neurostimulation. …”
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Versatile Click Chemistry-based Approaches to Illuminate DNA and RNA G-Quadruplexes in Human Cells by Angélique Pipier, David Monchaud

“…The existence and functional relevance of DNA and RNA G-quadruplexes (G4s) in human cells is now beyond debate, but how did we reach such a level of confidence? …”
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Establishment and validation of red fox (Vulpes vulpes) airway epithelial cell cultures at the air-liquid-interface by Andreas W. Oehm, Blandina I. Oliveira Esteves, Udo Hetzel, Marco P. Alves, Manuela Schnyder

“…Abstract The airway epithelium represents a central barrier against pathogens and toxins while playing a crucial role in modulating the immune response within the upper respiratory tract. …”
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Impact of elevated CO2 level and egg quiescence duration on gene expression in the peripheral olfactory system of Aedes aegypti by Sukritha Nalikkaramal, Sharon Rose Hill, Rickard Ignell

“…The transcriptome analysis demonstrates significant changes in the abundance of genes related to metabolism, xenobiotics degradation and chemosensory function, with the most pronounced effects observed in the CO2 sensing tissue, the maxillary palp. …”
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Research on Target Detection Algorithm for Solder Joint Defects Based on the Improved YOLOv8 by Chengkai Zhang, Xiaocui Feng, Pujun Mao, Fuyan Lv

“…Firstly, the FasterNet module was used to improve the C2f module of the baseline model, and the Efficient Multi-Scale Attention (EMA) attention mechanism was integrated to reduce model parameters and make the algorithm pay more attention to the solder joint targets. …”
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Mechanistic insights into the therapeutic effects on liver fibrosis in Wilson's disease: a transcriptomic and network pharmacology-based approach by Ying Ma, Yue Pu, Hong Chen, Lei Zhou, Bo Yang, Xiaofeng Huang, Juan Zhang

“…Furthermore, the target genes of DELncRNAs were identified, followed by GO functional enrichment and KEGG pathway analyses. DELncRNAs were validated using quantitative reverse transcription-polymerase chain reaction. …”
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A strong anti-inflammatory signature revealed by liver transcription profiling of Tmprss6-/- mice. by Michela Riba, Marco Rausa, Melissa Sorosina, Davide Cittaro, Jose Manuel Garcia Manteiga, Antonella Nai, Alessia Pagani, Filippo Martinelli-Boneschi, Elia Stupka, Clara Camaschella, Laura Silvestri

“…By using whole genome transcription profiling of the liver and analysis of spleen immune-related genes we identified several functional pathways differentially expressed in Tmprss6 KO mice, compared to IDA animals and thus irrespective of the iron status. …”
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Cysteinyl-Leukotriene Receptors and Cellular Signals by G. Enrico Rovati, Valérie Capra

“…The classification into subtypes of the cysteinyl-LT receptors (CysLTRs) was based initially on binding and functional data, obtained using the natural agonists and a wide range of antagonists. …”
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Impact of Temperature Stresses on Wheat Quality: A Focus on Starch and Protein Composition by Pei Han, Yaping Wang, Hui Sun

“…With climate change, maintaining wheat quality has become essential for the functional properties, end-use, commodity value, and nutritional benefits of wheat flour. …”
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Dissociating object directed and non-object directed action in the human mirror system; implications for theories of motor simulation. by Zarinah K Agnew, Richard J S Wise, Robert Leech

“…This study, for the first time, directly compares mirror responses, defined as the overlap between action execution and observation, during object directed and meaningless non-object directed actions. We present functional MRI data that demonstrate a clear dissociation between object directed and non-object directed actions within the human mirror system. …”
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A comparison of nucleosome organization in Drosophila cell lines. by Rebecca L Martin, John Maiorano, Greg J Beitel, John F Marko, Graham McVicker, Yvonne N Fondufe-Mittendorf

“…Changes in the distribution of nucleosomes along the genome influence chromatin structure and impact gene expression by modulating the accessibility of DNA to transcriptional machinery. …”
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Multimodal learning for enhanced SPECT/CT imaging in sports injury diagnosis by Zhengzheng Jiang, YaWen Shen

“…IntroductionSingle-photon emission computed tomography/computed tomography (SPECT/CT) imaging plays a critical role in sports injury diagnosis by offering both anatomical and functional insights. However, traditional SPECT/CT techniques often suffer from poor image quality, low spatial resolution, and limited capacity for integrating multiple data sources, which can hinder accurate diagnosis and intervention.MethodsTo address these limitations, this study proposes a novel multimodal learning framework that enhances SPECT/CT imaging through biomechanical data integration and deep learning. …”
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Light, Sound, and Melatonin: Investigating Multisensory Pathways for Visual Restoration by Dario Rusciano

“…However, direct evidence linking ipRGCs to audiovisual rehabilitation remains limited, with their role primarily inferred from anatomical and functional studies. Future implementations should prioritize quantitative optical metrics (e.g., melanopic irradiance, spectral composition) to standardize light-based interventions and enhance reproducibility. …”
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lncRNA HCG11 Promotes Colorectal Cancer Cell Malignant Behaviors via Sponging miR-26b-5p by Song Guo, Bingtan Song, Lin Li, Hesheng Li, Tao Yang, Lianmeng Cao, Jian Wang

“…However, whether lncRNA HLA complex group 11 (HCG11) played a functional role in CRC remained to be elucidated. Herein, we utilized qRT-PCR to analyze the expression of HCG11 and found that HCG11 was highly expressed in CRC cells. …”
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Biomaterial constructs for delivery of multiple therapeutic genes: a spatiotemporal evaluation of efficacy using molecular beacons. by Jennifer C Alexander, Shane Browne, Abhay Pandit, Yury Rochev

“…The dual gene releasing collagen-based scaffold provided both sustained and delayed release of functional polyplexes in vitro over a 14 day period which was corroborated with variation in expression levels seen using RT-PCR and MB imaging. …”
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Natural sounds can be reconstructed from human neuroimaging data using deep neural network representation. by Jong-Yun Park, Mitsuaki Tsukamoto, Misato Tanaka, Yukiyasu Kamitani

“…Although decoding visual content from functional MRI (fMRI) has seen significant success, reconstructing arbitrary sounds remains challenging due to the fine temporal structure of auditory signals and the coarse temporal resolution of fMRI. …”
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Fatty acid composition of total lipids and phospholipids of muscular tissue and brain of rats under the impact of vibration by N. M. Kostyshyn, M. R. Grzegotsky, J. F. Rivis

“…These changes indicate worsening of structural and functional organization of muscles and brain cell membranes of rats due to increased viscosity of lipids and changes in their intramembrane dynamics.…”
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Amphetamine sensitization alters reward processing in the human striatum and amygdala. by Owen G O'Daly, Daniel Joyce, Derek K Tracy, Adnan Azim, Klaas E Stephan, Robin M Murray, Sukhwinder S Shergill

“…These data show for the first time in humans that AS changes the functional impact of acute stimulant exposure on the processing of reward-related information within dopaminoceptive regions. …”
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Loss of serine/threonine protein phosphatase 6 severely impairs sexual stage development in malaria parasite Plasmodium berghei. by Yonghui Feng, Wenyan Gao, Chengqi Wang, Shuangrui Shi, Dan Zhou, Lin Sun, Liying Zhu, Liwang Cui, Yaming Cao, Xiaotong Zhu

“…Here, we performed a functional analysis of the Plasmodium berghei Ser/Thr protein phosphatase 6 (PbPP6), which is associated with the plasma membrane of macrogametes and ookinetes. …”
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Black mulberry (Morus Nigra) callus tissue lysate effect on mouse blood leukocytes by Pleskanovskaya S. A., Goshaev G., Semina I. F.

“…The effect of CCL on the functional activity of mouse blood leukocytes (MBL) was studied in a leucocytes migration inhibition reaction (LMIR) in a modification of one of the authors of the article. …”
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