THE CHANGES OF THE ELECTROPHYSIOLOGICAL PROPERTIES OF NEURONS BY THE ACTION OF SEVOFLURANE AND THEIR ROLE IN THE MECHANISMS OF PRECONDITIONING AND CYTOPROTECTION by A. I. Vislobokov, Yu. S. Polushin, A. Yu. Polushin, V. V. Alferova

“…The  repeated neuron exposure with  the  same anesthetic is  always reproduced followed by  the  florid hyperpolarization. The  modulation of  the  electrical activity with  sevoflurane (the  hyperpolarization of  the  neurons and the decrease/termination of AP generation that evidenced the "improvement" of their functional status) may be the basis for the preconditioning, neuro- and cardioprotection.…”
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Electric Drive Discrete Control System with Automatic Switching-On Reserve for Autonomous Settlement by Tsytovich L.I., Brylina O.G., Nesterov A.S., Tyugaev A.V, Loginova N.A, Lopukhova E.A.

“…The system provides automatic switching to a reserve control channel at refusal of any of the functional elements of the working regulation channel. …”
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Dynamic anti-correlations of water hydrogen bonds by Lucas Gunkel, Amelie A. Ehrhard, Carola S. Krevert, Bogdan A. Marekha, Mischa Bonn, Maksim Grechko, Johannes Hunger

“…Broader inhomogeneous linewidths of the OD band of HOD compared to the symmetric and asymmetric OD stretching modes of D2O together with density functional theory calculations provide evidence for markedly anti-correlated H-bonds: water preferentially forms one weak and one strong H-bond. …”
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A Protocol to Purify Human Mediator Complex From Freestyle 293-F Cells by Hui- Tang, Kuang- Tsai, Ti- Chao

“…This protocol provides a time- and cost-efficient way to purify the endogenous Mediator complex for structural- and functional-based studies.…”
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A phase II double-blind multicentre, placebo-controlled trial to assess the efficacy and safety of alpelisib (BYL719) in paediatric and adult patients with Megalencephaly-CApillary... by Jean-Marc Treluyer, Benedicte Demeer, Laurence Faivre, Marc Bardou, Nathalie Boddaert, Paul Kuentz, Florence Petit, Christine Francannet, Pierre Vabres, Nadia Bahi-Buisson, Estelle Colin, Laurent Guibaud, Romaric Loffroy, Maxime Luu, Caroline Racine, Aurore Garde, Philippe Khau Van Kien, Aurore Curie, Nawale Hadouiri, Aurélie Espitalier, Agnès Maurer, Maud Carpentier, Adélaide Rega, Mouna Chebbi, Julie Charligny, Guillaume Canaud, Camille Fleck, Amelie Cransac, Elise Boucher-Brischoux, Adélaïde Brosseau-Beauvir, Florian Cherik, Alice Phan, Michaela Semeraro, Marion Nys, Charles Joris Roux, Alinoë Lavillaureix, Isabelle Maruani

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Methylprednisolone Administration Following Spinal Cord Injury Reduces Aquaporin 4 Expression and Exacerbates Edema by Eibar Ernesto Cabrera-Aldana, Fernando Ruelas, Cristina Aranda, Ruth Rincon-Heredia, Angelina Martínez-Cruz, Alejandro Reyes-Sánchez, Gabriel Guizar-Sahagún, Luis B. Tovar-y-Romo

“…We studied the functional expression of AQP4 modulated by MP following SCI in an experimental model in rats along with the associated changes in the permeability of the blood-spinal cord barrier. …”
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Human umbilical cord mesenchymal stem cells-derived extracellular vesicles as a therapeutic approach to ameliorate bladder injury in animal models of radiation cystitis by Parmida Sadat Pezeshki, Amir Mahboubi, Negar Mohammadi Ganjaroudi, Reza Ghalehtaki, Masoumeh Majidi Zolbin, Samaneh Salarvand, Somayeh Jolany Vangah, Asma Mehrjoo, Abdol-mohammad Kajbafzadeh

“…Conclusions Local huMSC-EVs therapy effectively reduces RC-related bladder injury and preserves function, likely by modulating inflammatory response and epithelial regeneration. …”
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Effectiveness of Probiotics, Prebiotics, and Symbiotic Supplementation in Cystic Fibrosis Patients: A Systematic Review and Meta-Analysis of Clinical Trials by Freiser Eceomo Cruz Mosquera, Claudia Lorena Perlaza, Anisbed Naranjo Rojas, Saray Murillo Rios, Alejandra Carrero Gallego, Sara Isabel Fischersworring, Juan Sebastián Rodríguez, Yamil Liscano

“…Sensitivity analyses did not modify the effect of the intervention on pulmonary function or exacerbation frequency, supporting the robustness of the findings. …”
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High directional optical transmitter with phased array of nanoptical emitters and efficient error correction for long distance space communications by Elisa Bazzani, Anna Valeria Guglielmi, Roberto Corvaja, Nicola Laurenti, Filippo Romanato, Gianluca Ruffato, Andrea Vogliardi, Giuseppe Vallone, Lorenzo Vangelista, Paolo Villoresi

“…We also discuss the lower and upper limits of the beam steering technique as a function of the array and emitter size, respectively. …”
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Texture-preserving and information loss minimization method for infrared and visible image fusion by Qiyuan He, Yongdong Huang

“…TPFusion consists of the following key components: a multi-scale feature extraction module for enhancing the capability of capturing features; a texture enhancement module and contrast enhancement module, which helps to preserve fine-grained textures and extract salient contours and contrast information; a dual-attention fusion module for fusing the features extracted from the source images; an information content based loss function minimizing the feature discrepancy between the fused images and the source images and effectively reducing the information loss. …”
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Oxidation-Triggered Formation of Diradical Cations from Paramagnetic Molecules and Their Spin Density Evolution by Di Wang, Dan Yao, Xinyu Li, Lingli Shi, Chunyuan Wang, Jie Li, Weili Kong, Yongliang Qin, Martin Baumgarten

“…UV-Vis absorption spectroscopy, cyclic voltammetry (CV), electron paramagnetic resonance (EPR), and density functional theory (DFT) were employed to confirm the formation of diradical cations during the redox processes. …”
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DAMI-YOLOv8l: A multi-scale detection framework for light-trapping insect pest monitoring by Xiao Chen, Xinting Yang, Huan Hu, Tianjun Li, Zijie Zhou, Wenyong Li

“…The DAMI-YOLOv8l model integrates three key innovations: the Depth-wise Multi-Scale Convolution (DMC) module, the Attentional Scale Sequence Fusion with a P2 detection layer (ASFP2) neck structure, and a novel bounding box regression loss function named Minimum Point Distance inner Intersection over Union (MPDinner-IoU). …”
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IL-6 Negatively Regulates IL-22Rα Expression on Epidermal Keratinocytes: Implications for Irritant Contact Dermatitis by Benjamin Frempah, Lerin R. Luckett-Chastain, Randle M. Gallucci

“…Furthermore, it was shown that IL-6 negatively regulates the expression of IL-22Rα on epidermal keratinocytes. This effect is functional as the effects of IL-22 on keratinocyte proliferation and differentiation were markedly reduced when keratinocytes were pretreated with IL-6 prior to IL-22 treatment. …”
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Fruit Astringency: Mechanisms, Technologies, and Future Directions by Wanru Zhao, Meizhu Zheng, Xue Li, Kai Song, Dongfang Shi

“…Finally, future research directions are discussed, emphasizing the importance of precise genetic improvement using tools such as gene editing, developing green and efficient processes, achieving intelligent process control, and focusing on synergistic quality regulation and the exploration of functional value. This review aims to provide an integrated knowledge framework for developing innovative, efficient, safe, and sustainable fruit de-astringency solutions, offering a scientific reference to advance technological upgrades in the fruit industry.…”
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A framework for assessing grey multitasking effectiveness of satellite communication constellation by Ruirui Shao, Ximing Wang, Su Gao, Yuhong Li, Weiqing You, Qian Zhang

“…Secondly, the network structure is modeled using the Satellite Tool Kit, which aids in determining the completion times and variances for each functional module. Thirdly, the multitasking effectiveness of the constellation is quantified by combining the effectiveness and importance weights of each communication link task. …”
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Direct comparisons of neural activity during placebo analgesia and nocebo hyperalgesia between humans and rats by Damien C. Boorman, Lewis S. Crawford, Luke A. Henderson, Kevin A. Keay

“…Using c-Fos immunohistochemistry in rats and fMRI in humans, we examined neural activity in 70 pain-related brain regions, identifying both conserved and species-specific connectivity changes. Functional connectivity analysis, refined by pruning connections based on known anatomical pathways, revealed significant overlap in key regions, including the amygdala, anterior cingulate cortex, and nucleus accumbens, highlighting conserved circuits driving placebo and nocebo responses. …”
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RTide: Automating the Tidal Response Method by Thomas Monahan, Tianning Tang, Stephen Roberts, Thomas A. A. Adcock

“…Moreover, specialized approaches impose problem‐specific functional forms and rely on auxiliary data, limiting their applicability across different nonstationary tidal processes. …”
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Response of dorsal horn neurons in mice to high‐frequency (kHz) biphasic stimulation is not sensitive to local temperature rise by Sergei Karnup, Stephanie Daugherty, Changfeng Tai, Naoki Yoshimura

“…This is equivalent to the release of more heat in a surrounding tissue, which may change the functional state of affected neural elements. In the case of SCS, plausible candidates to be affected by thermal a component of kHz‐frequency electric field stimulation (kHz‐FS) are dorsal column axons and neurons of the superficial layers of the dorsal horn. …”
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Development of an embedded diagnostic tool for visual misalignment screening by Daniel Soto Rodriguez, Andres Eduardo Rivera Gomez, Ruthber Rodriguez Serrezuela

“…The graphical interface allows users to capture or upload images, perform automated analysis, generate diagnostic PDF reports, and access a gamified treatment module. Functional validation included a proprietary dataset of 27 images, achieving a 96.30 % classification accuracy. …”
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Profiling with senescence-associated secretory phenotype score identifies GDC-0879 as a small molecule sensitizing glioblastoma to anti-PD1 by Yang Liu, Yuan Feng, Lin Cheng, Yangxi Xu, Anhua Wu, Peng Cheng

“…Then, we validate this score with functional assays and transcriptomic profiling of Doxorubicin-induced senescence GBM cells. …”
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