Pharmacologically targeting Schwann cells to improve regeneration following nerve damage by Alaa A. Alhamdi, Alaa A. Alhamdi, Shona Mackie, Shona Mackie, Ryan P. Trueman, Ryan P. Trueman, Melissa L. D. Rayner, Melissa L. D. Rayner

“…Schwann cells provide essential support for nerve growth and survival following peripheral nerve damage by producing various growth factors and other signalling molecules. Modulating the proliferation, differentiation, migration, or myelination of Schwann cells could result in accelerated repair and regeneration of injured nerves, ultimately leading to improved motor and sensory function. …”
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Thermal nonreciprocity tuned by wrinkle patterns in graphene by Bohan Li, Qingxiang Ji, Qi Zhang, Changguo Wang, Muamer Kadic

“…The findings provide insights into the physics of thermal transport in wrinkled graphene, and paves a new avenue for mechanically modulating thermal nonreciprocity. Our method to obtain thermal nonreciprocity is reversible, tunable and controllable, meanwhile remains structural integrity, which benefits functional applications such as heat management in electronics.…”
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Design of Silicon Nitride Based TE-Pass Polarizer at 850 nm for Integrated Fiber Optic Gyroscope by Zhiyu Guo, Ningfang Song, Linghai Kong, Jing Jin, Zuchen Zhang

“…The proposed polarizer could directly edge-couple to the thin film lithium niobate (TFLN) modulator with a negligible loss (<0.19 dB) to form a combined hybrid modulator, which integrates the function of modulating, splitting, and polarizing. …”
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Stem cell extracellular vesicles: a new dawn for anti-inflammatory treatment of neurodegenerative diseases by Miao Yu, Miao Yu, Hongxia Ma, Xiaoyi Lai, Jiannan Wu, Mengmeng Shen, Junqiang Yan, Junqiang Yan

“…Their vesicular structure, with a diameter of 30–150 nm, can penetrate the blood–brain barrier and modulate the activity of microglia and astrocytes by delivering functional molecules. …”
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Cross‐species chemogenomic profiling reveals evolutionarily conserved drug mode of action by Laura Kapitzky, Pedro Beltrao, Theresa J Berens, Nadine Gassner, Chunshui Zhou, Arthur Wüster, Julie Wu, M Madan Babu, Stephen J Elledge, David Toczyski, R Scott Lokey, Nevan J Krogan

“…We found that compound–functional module relationships are more conserved than individual compound–gene interactions between these two species. …”
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Regulation of nanomaterials in peripheral nerve regeneration from a microenvironmental perspective: biological effects and mechanisms by Xiner Tan, Yiyuan Kang, Wei Du, Ziyang Wang, Jia Liu, Longquan Shao

“…The pathological microenvironment following peripheral nerve injury (PNI) comprises a dynamic interplay of cellular and molecular events that critically influence neuronal regeneration and functional recovery. Recent advances in nanotechnology have demonstrated the transformative potential of nanomaterials (NMs) in nerve repair, capitalizing on their unique physicochemical properties to engineer a pro-regenerative milieu that facilitates axonal regrowth. …”
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Basal ganglia deep brain stimulation restores cognitive flexibility and exploration-exploitation balance disrupted by NMDA-R antagonism by Nir Asch, Noa Rahamim, Anna Morozov, Uri Werner-Reiss, Zvi Israel, Rony Paz, Hagai Bergman

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The role of A-kinase anchoring proteins in cardiovascular diseases and recent advances by Xu Zhang, Xu Zhang, Feng Zhu, Zhaoqiang Xiao, Hegui Wang

“…This review provides a comprehensive analysis of AKAPs’ involvement in the pathogenesis of cardiovascular diseases, emphasizing their key function in coordinating diverse signaling molecules, directing them to specific cellular microdomains, and minimizing signal interference. …”
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Human colonic intraepithelial lymphocytes regulate the cytokines produced by lamina propria mononuclear cells by P. Hoang, J. P. Dehennin, Li Li, C. Sibille, A. Geubel, J. P. Vaerman

“…Using an in vitro autologous human system, the immunomodulatory function of colonic intraepithelial lymphocytes (IEL) on cytokine production by lamina propria mononuclear cells (LPMNC) has been investigated. …”
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Repetitive Control Compensation Joint Control for Hydraulic Quadruped Robot by SHAO Jun-peng, XU Yan-shuai, SUN Gui-tao, LIU Meng-meng

“…According to the mathematical model of the electro.hydraulic servo.system of the hydraulic quadruped robot, the transfer function of the simplified hydraulic position driving unit is obtained. …”
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Regulation of embryonic cell adhesion by the prion protein. by Edward Málaga-Trillo, Gonzalo P Solis, Yvonne Schrock, Corinna Geiss, Lydia Luncz, Venus Thomanetz, Claudia A O Stuermer

“…Zebrafish and mouse PrP mRNAs can partially rescue this knockdown phenotype, indicating conserved PrP functions. Using zebrafish, mouse, and Drosophila cells, we show that PrP: (1) mediates Ca(+2)-independent homophilic cell adhesion and signaling; and (2) modulates Ca(+2)-dependent cell adhesion by regulating the delivery of E-cadherin to the plasma membrane. …”
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Sodium citrate pretreatment enhances CAR-T cell persistence and anti-tumor efficacy through inhibition of calcium signaling by Xuechen Yin, Wenwen Chen, Xudong Ao, Luxia Xu, Jiujiu Cao, Tinghui Huang, Junqing Liang, Jianhua Hu, Jiaqi Liu, Xinping Wang, Wenying Li, Muya Zhou, Lingfeng He, Zhigang Guo

“…The characteristics and functionality of sodium citrate-pretreated CAR-T cells were assessed through in vitro and in vivo experiments. …”
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Regulation of hedonic feeding rhythms by circadian clocks in leptin-receptive neurons by Jazmin Osorio-Mendoza, Jana-Thabea Kiehn, Sarah Stenger, Keno O. Heinen, Laura Griewahn, Christiane E. Koch, Undine Haferkamp, Violetta Pilorz, Johanna L. Barclay, Parth Joshi, Lisbeth Harder, Olaf Jöhren, Peter Kühnen, Gregor Eichele, Henrik Oster

“…In mammals, the circadian system consists of a master clock in the suprachiasmatic nucleus (SCN), which synchronizes subordinate tissue clocks, including extra-SCN central nervous system (CNS) clocks involved in functions such as sleep and appetite regulation. Appetite is controlled by both homeostatic and non-homeostatic (hedonic) circuits. …”
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The dual regulatory effects of intestinal microorganisms and their metabolites in gouty arthritis pathogenesis: a balance between promotion and inhibition by Peng Qi, Longcan Li, Jianrong Zhang, Ling Ren, Xingwen Xie

“…The gut microbiome profoundly influences gout pathogenesis, progression, and management by affecting uric acid metabolism, immune responses, and intestinal barrier function. Studies reveal that gut microorganisms exert a dual role in gout development. …”
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Lactiplantibacillus plantarum FRT4 protects against fatty liver hemorrhage syndrome: regulating gut microbiota and FoxO/TLR-4/NF-κB signaling pathway in laying hens by Daojie Li, Kun Meng, Guohua Liu, Zhiguo Wen, Yunsheng Han, Weiwei Liu, Xin Xu, Liye Song, Hongying Cai, Peilong Yang

“…This efficacy is attributed to its antioxidant and anti-inflammatory properties, which are mediated by modulating the structure and function of gut microbiota, and further intervening in the FoxO/TLR-4/NF-κB signaling pathway. …”
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Peripheral cranio-spinal nerve communication for trapezius muscle control using axonal profiling through immunostaining by Miri Kim, In-Seung Yeo, Tae-Hyeon Cho, Ju-Eun Hong, Shin Hyung Kim, Hun-Mu Yang

“…This study used immunostaining (using antibodies against neurofilament 200 for all axons, choline acetyltransferase for cholinergic axons, tyrosine hydroxylase for sympathetic axons, and alpha 3 sodium potassium ATPase for proprioceptive afferent axons) of human samples to verify the functional contributions of nerves. Study highlights the pivotal role of C3 and C4 in regulating precise movements of trapezius, contributing to motor control, proprioceptive feedback, and sympathetic modulation. …”
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Parallel wave-based analog computing using metagratings by Rajabalipanah Hamid, Momeni Ali, Rahmanzadeh Mahdi, Abdolali Ali, Fleury Romain

“…In this paper, we propose a multi-functional metagrating to modulate both spatial and angular properties of the input signal whereby both symmetric and asymmetric optical transfer functions are realized using high-order space harmonics. …”
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Antihypertensive, Anti-Inflammatory, and Antiangiogenic In Silico Activity of Lactoferrin-Derived Peptides of Equine Milk Hydrolysate by Meiramkul Narmuratova, Dmitriy Berillo, Zhanar Narmuratova, Pavel Tarlykov, Assiya Serikbayeva, Shattyk Kanayat

“…Conclusions: The three-dimensional modeling of lactoferrin hydrolysate peptides was performed to support the development of computational models or simulations, as well as to investigate their potential antimicrobial, anti-inflammatory, or immune-modulating functions in clinical or nutritional applications.…”
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A mini-hairpin shaped nascent peptide blocks translation termination by a distinct mechanism by Yushin Ando, Akinao Kobo, Tatsuya Niwa, Ayako Yamakawa, Suzuna Konoma, Yuki Kobayashi, Osamu Nureki, Hideki Taguchi, Yuzuru Itoh, Yuhei Chadani

“…Abstract Protein synthesis by ribosomes produces functional proteins but also serves diverse regulatory functions, which depend on the coding amino acid sequences. …”
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Cerebellar Transcranial Direct Current Stimulation Effects on Saccade Adaptation by Eric Avila, Jos N. van der Geest, Sandra Kengne Kamga, M. Claire Verhage, Opher Donchin, Maarten A. Frens

“…Transcranial direct current stimulation (tDCS) induces changes in neuronal excitability in a polarity-specific manner and offers a modulatory, noninvasive, functional insight into the learning aspects of different brain regions. …”
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