Regulating Adsorption Behaviors in Crystalline Porous Materials by External Electric Fields by Yang Yang, Tianyi Zhang, Tianqi Wang, Teng Zhou, Youssef Belmabkhout, Qinfen Gu, Jin Shang

“…In this work, it is aimed to summarize recent advances and identify gaps in the understanding of E‐field effects on CPMs, providing a foundation for the rational development of next‐generation materials with E‐field modulated functionalities.…”
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Cryptic genetic variation shapes the fate of gene duplicates in a protein interaction network by Soham Dibyachintan, Alexandre K. Dubé, David Bradley, Pascale Lemieux, Ugo Dionne, Christian R. Landry

“…Abstract Paralogous genes are often functionally redundant for long periods of time. While their functions are preserved, paralogs accumulate cryptic changes in sequence and expression, which could modulate the impact of future mutations through epistasis. …”
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An Efficient and Cost-Effective Vehicle Detection and Tracking System for Collision Avoidance in Foggy Weather by Naeem Raza, Muhammad Asif Habib, H. M. Sajid Imran, Abdul Qayum, Sajida Perveen, Sohail Jabbar, Shahzad Sarwar, Mudassar Ahmad

“…The backbone network of the baseline YOLO-V5s algorithm is optimized by integrating the SimSPPF module, a variant of the standard SPPF module. Furthermore, diverse distance metrics and loss functions, such as CIOU, DIOU, EIOU, GIOU, and SIOU, are considered to enhance the baseline YOLO-V5s bounding box localization accuracy. …”
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Optimization of cryoprotectants and storage temperatures for preserving viability and probiotic properties of lyophilized bacterial strains from chicken gut. by Dipankar Sardar, Istiaq Morol, Johra Bari, Amalan Sarkar, Adnan Habib

“…Probiotics, particularly strains from the genera Bacillus, Lactobacillus, and Staphylococcus, play a vital role in gut health, immune modulation, and pathogen inhibition. However, environmental stressors during storage often compromise their long-term viability and probiotic functionality. …”
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Etiology of Late-Onset Alzheimer’s Disease, Biomarker Efficacy, and the Role of Machine Learning in Stage Diagnosis by Manash Sarma, Subarna Chatterjee

“…Employing a systems biology approach, our analysis encompassed the genetic, epigenetic, metabolic, and environmental factors that modulate the molecular networks and pathways. These factors affect the brain’s structural integrity, functional capacity, and connectivity, ultimately leading to the manifestation of the disease. …”
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A new methodology to associate SNPs with human diseases according to their pathway related context. by Burcu Bakir-Gungor, Osman Ugur Sezerman

“…Importantly, within these pathways, the associations between some of these additionally found genes, such as HLA-C, HLA-G, PRKCQ, PRKCZ, TAP1, TAP2 and RA were verified by either OMIM database or by literature retrieved from the NCBI PubMed module. With the whole-genome sequencing on the horizon, we show that the full potential of GWAS can be achieved by integrating pathway and network-oriented analysis and prior knowledge from functional properties of a SNP.…”
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Crosstalk Within the Intestinal Epithelium: Aspects of Intestinal Absorption, Homeostasis, and Immunity by Liang-En Yu, Wen-Chin Yang, Yu-Chaun Liang

“…To maximize the effect of a healthy gastrointestinal tract (GIT), an understanding of the regulation of intestinal functions is needed. Proper intestinal functions depend on the activity, composition, and behavior of intestinal epithelial cells (IECs). …”
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Targeting epigenetic and post-translational modifications of NRF2: key regulatory factors in disease treatment by Xinyi Yang, Yingchao Liu, Jinghao Cao, Cuiyun Wu, Lusheng Tang, Wenxia Bian, Yuhan Chen, Lingyan Yu, Yunyi Wu, Sainan Li, Yuhuan Shen, Jun Xia, Jing Du

“…PTMs, including phosphorylation, ubiquitination, and acetylation, play a pivotal role in modulating NRF2’s stability, activity, and subcellular localization, thereby precisely controlling its function in the antioxidant response. …”
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Unveiling macrophage dynamics and efferocytosis-related targets in diabetic kidney disease: insights from single-cell and bulk RNA-sequencing by Binshan Zhang, Yunqi Wu, Zhongli Wang, Suhua Gao, Hongyan Liu, Yao Lin, Pei Yu, Pei Yu

“…Further analysis pointed to the most enrichment of macrophage function is the phagosome. We overlapped the DEGs with efferocytosis-related genes and identified key genes, including CD36, ITGAM, and CX3CR1, which exhibited significant correlations with macrophages and T cells. …”
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Ovarian Epithelial-Stromal Interactions: Role of Interleukins 1 and 6 by Kamisha T. Woolery, Patricia A. Kruk

“…The objective of this paper is to provide a brief consideration of ovarian surface epithelial-stromal interactions in regard to normal physiological function and tumor progression as influenced by two potentially key interleukins, interleukins-1 (IL-1) and -6 (IL-6), present in the microenvironment. …”
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Deciphering Arabidopsis Aquaporin Networks: Comparative Analysis of the STRING and BioGRID Interactomes by Alvaro Lopez-Zaplana

“…Therefore, understanding the function and interactions of these proteins with others—known as interactomes—is of significant agronomic and biological interest. …”
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PGRN as an emerging regulator of lipid metabolism in neurodegenerative diseases by Yiyue Shi, Wenyu Hou, Bei Li, Caihong Zhu

“…Progranulin (PGRN) is a lysosomal glycoprotein encoded by GRN. Loss-of-function mutations or variants of GRN have been linked to various neurodegenerative diseases. …”
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Exploring the correlation between Drp1 protein and the neurotoxicity of propofol by Pu Guo, Jing Mei

“…Dynamin-related protein 1 (Drp1) is a key regulator of mitochondrial fission that can modulate the dynamic balance of mitochondria and plays an important role in maintaining mitochondrial morphology and function. …”
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Sex hormones and immune regulation in ovarian cancer by Rui Zhao, Wenqin Lian, Qiong Xu

“…We delve into the mechanisms by which these hormones influence immune cell function, modulate immune checkpoints, and alter the tumor microenvironment. …”
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Germ granule-mediated mRNA storage and translational control by Hoang-Anh Pham-Bui, Mihye Lee

“…Germ cells depend on specialized post-transcriptional regulation for proper development and function, much of which is mediated by dynamic RNA granules. …”
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Renal Implications of Dysregulated Protein Homeostasis: Insights into Ubiquitin–Proteasome and Autophagy Systems by Charlotte Delrue, Marijn M. Speeckaert

“…The ubiquitin–proteasome system (UPS) and autophagy maintain protein homeostasis, which is critical to cellular function and survival. The dysregulation of these pathways has been recognized as a hallmark of acute kidney injury and chronic kidney disease. …”
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Comparison of Two Types of Combined Measures, STI and U50, for Predicting Speech Intelligibility in Classrooms by Young-Ji CHOI

“…The measured impulse responses of the classrooms were used to determine the modulation transfer function, $m(F)$, for the STI calculation according to IEC 60268-16. …”
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Characterization of the Gut Microbiota in Patients with Psoriasis: A Systematic Review by Yingjun Gao, Yanfeng Lou, Yun Hui, Huan Chen, Hong Sang, Fang Liu

“…Future research should prioritize the functional characterization of microbiota–host interactions to optimize therapeutic applications.…”
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Quantitative Approach to Explore Regulatory T Cell Activity in Immuno-Oncology by Alejandro Serrano, Sara Zalba, Juan Jose Lasarte, Iñaki F. Troconiz, Natalia Riva, Maria J. Garrido

“…Characterization of immunological and functional profiles could help to identify the mechanisms that need to be inhibited or activated to ensure Treg modulation in the tumor. …”
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Jingui Shenqi Wan alleviates bone loss induced by primary osteoporosis by inhibiting osteoblast pyroptosis by Yuwangxuan Qian, Yihe Yu, Fan Yang, Qixing Liang, Dan Xu, Jiaxiang Chen, Xueqin Hu

“…Additionally, JGSQW significantly downregulates the expression of GSDMD in osteoblasts and mitigates the abnormal release of inflammatory factors, thereby maintaining the normal functional activities of osteoblasts. Conclusion JGSQW may effectively mitigate the progression of estrogen deficiency-induced PMOP by inhibiting the dysregulated activation of osteoblast pyroptosis.…”
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