Nitric oxide dysregulation in platelets from patients with advanced Huntington disease. by Albino Carrizzo, Alba Di Pardo, Vittorio Maglione, Antonio Damato, Enrico Amico, Luigi Formisano, Carmine Vecchione, Ferdinando Squitieri

“…Nitric oxide (NO) is a biologically active inorganic molecule involved in the regulation of many physiological processes, such as control of blood flow, platelet adhesion, endocrine function, neurotransmission and neuromodulation. In the present study, for the first time, we investigated the modulation of NO signaling in platelets of HD patients. …”
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Targeting the HGF-cMET Axis in Hepatocellular Carcinoma by Neeta K. Venepalli, Laura Goff

“…The authors review HGF-cMET structure and function in normal tissue and in HCC, cMET inhibition in HCC, and future strategies for biomarker identification.…”
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Dynamics Feature and Synchronization of a Robust Fractional-Order Chaotic System by Xuan-Bing Yang, Yi-Gang He, Chun-Lai Li

“…The important finding by analysis is that the position of signal x3 descends at the speed of 1/c as the parameter b increases, and the signal amplitude of x1, x2 can be controlled by the parameter m in terms of the power function with the index −1/2. What is more, the dynamics remains constant with the variation of parameters b and m. …”
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Effects of anesthetics on development of gynecological cancer by Yingxiang Cheng, Yunzhi Wu, Lingzhong Xu

“…Anesthetic drugs may influence cancer metabolic reprogramming and modulate immune function through the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic nervous system (SNS). …”
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Computer Teaching System Based on Internet of Things and Machine Learning by Lei Chen, Li Zhang

“…The hardware structure is designed according to the functions of each module of the system, in which the student learning module is composed of a teaching coordination agent and a number of other agents, responsible for the presentation of specific teaching materials, problem solving, knowledge sharing through a collaborative mechanism, and providing personalized teaching basis for the system. …”
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The Impact of Omega-3 Fatty Acids on the Onset and Management of Alzheimer's Disease by Marta Biskup, Aleksandra Bartoszek, Karolina Kopeć, Agnieszka Marut, Jagoda Misiuk, Julia Adamiuk, Adriana Skuba, Katarzyna Załuska, Agnieszka Świdniak, Sylwia Nykiel

“…Omega-3 acids have been linked to improved neuronal function and reduced cognitive decline in aging populations. …”
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BLH3 Regulates the ABA Pathway and Lignin Synthesis Under Salt Stress in <i>Lilium pumilum</i> by Wenhao Wan, Lingshu Zhang, Xingyu Liu, Huitao Cui, Miaoxin Shi, Hao Sun, Wei Yang, Xinran Wang, Fengshan Yang, Shumei Jin

“…Additionally, the functional analysis of the BLH transcription factor family provides new insights into how crops adapt to the extreme growth environment of saline-alkali soils.…”
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Fecal Microbiota and Performance of Dairy Cattle from a West Mexican Family Dairy Farm Supplemented with a Fiber-Degrading Enzymatic Complex by José Martín Ruvalcaba-Gómez, Ramón Ignacio Arteaga-Garibay, Luis Miguel Anaya-Esparza, Lorena Jacqueline Gómez-Godínez, Jazmín Guadalupe Martínez-Sotelo, Elías Hernández-Cruz, Luis Eduardo Arias-Chávez

“…The structure and composition of fecal bacterial communities, as well as PICRUSt2-based functional prediction of bacterial communities, were also evaluated. …”
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Increased antitumor efficacy of PD-1-deficient melanoma-specific human lymphocytes by Nathalie Labarrière, Lucine Marotte, Sylvain Simon, Virginie Vignard, Emilie Dupre, Malika Gantier, Jonathan Cruard, Jean-Baptiste Alberge, Melanie Hussong, Cecile Deleine, Jean-Marie Heslan, Jonathan Shaffer, Tiffany Beauvais, Joelle Gaschet, Emmanuel Scotet, Delphine Fradin, Anne Jarry, Tuan Nguyen

“…Background Genome editing offers unique perspectives for optimizing the functional properties of T cells for adoptive cell transfer purposes. …”
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Small target drone algorithm in low-altitude complex urban scenarios based on ESMS-YOLOv7 by Yuntao Wei, Xiujia Wang, Chunjuan Bo, Zhan Shi

“…Additionally, the SIOU loss function is employed to increase the model's robustness. …”
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Animal Models of MS Reveal Multiple Roles of Microglia in Disease Pathogenesis by Zhen Gao, Stella E. Tsirka

“…Microglia activation classically accompanies MS development, and regulation of microglia function changes the outcome of the disease. In this paper, we review the contributions of microglia to MS pathogenesis and discuss microglial functions in antigen presentation, cytokine release, and phagocytosis. …”
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What Are the Molecules Involved in Regulatory T-Cells Induction by Dendritic Cells in Cancer? by Rodrigo Nalio Ramos, Cristiano Jacob de Moraes, Bruna Zelante, José Alexandre M. Barbuto

“…Dendritic cells (DCs) are essential for the maintenance of homeostasis in the organism, and they do that by modulating lymphocyte priming, expansion, and response patterns according to signals they receive from the environment. …”
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TFE3-mediated lysosomal biogenesis and homeostasis alleviates arsenic-induced lysosomal and immune dysfunction in macrophages by Guowei Xu, Haiyang Chen, Zheng Cong, Ling Zhou, Ning Zhao, Yuqing Yang, Ting Li, Xuping Liu, Yi Wang, Bing Li

“…Targeting the MiT/TFE family may provide new strategies for modulating lysosomal homeostasis and immune function.…”
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A bioinformatics-driven approach to identify biomarkers and elucidate the pathogenesis of type 2 diabetes concurrent with pulmonary tuberculosis by Yan Liu, Yonglan Pu, Jie Wang, Zhiyong Li, Songliang Liu, Shenjie Tang

“…Weighted gene co-expression network analysis (WGCNA) and Gene Ontology and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were employed to identify key gene modules and functions related to PTB + T2DM. Immune cell infiltration and drug sensitivity were compared between PTB + T2DM patients and healthy controls (HCs), with a bioinformatic approach. …”
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A Study on the Consistency and Efficiency of Student Performance Evaluation Methods: A Mathematical Framework and Comparative Simulation Results by Cecilia Leal-Ramírez, Héctor Alonso Echavarría-Heras, Enrique Villa-Diharce, Horacio Haro-Avalos

“…Methods: We propose a scheme aimed at identifying inconsistencies in student evaluation related to the mathematical framework of the used grading method. To explain the functioning of our construct, we provide mathematical representation of conventional grading methods, including summative assessments, rubrics, and the Systematic Task-Based Assessment Method (STBAM) that we have recently developed, which incorporates both traditional and fuzzy logic-based grading modules. …”
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Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics by Asma Bibi, Asma Bibi, Famin Zhang, Famin Zhang, Jilong Shen, Jilong Shen, Ahmad Ud Din, Yuanhong Xu, Yuanhong Xu

“…Although antibiotics disrupt the gut microbiota’s fundamental structure, the mechanisms that modulate the response and their impact on brain function are still unclear. …”
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Leucyl-tRNA synthetase regulates casein synthesis in dairy cows via the mTORC1-LAT1 pathway by Yongding Ke, Ximeng Du, Binglan Chen, Xi Chen, Chengchuang Song, Xingtang Fang, Yanhong Wang, Chunlei Zhang

“…Despite its significance, the precise mechanisms of these functions are yet to be fully delineated. This study examines LARS and its role in modulating milk protein synthesis. …”
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Monolithically integrated ultra-wideband photonic receiver on thin film lithium niobate by Marco Moller de Freitas, Xiaofeng Zhu, Md Saheed Ullah, Shouyuan Shi, Peng Yao, Garrett Schneider, Dennis W. Prather

“…The challenge, however, is the ability to monolithically integrate both electronic and photonic devices into functional components that provide ultra-wideband performance up into the millimeter wave and terahertz regions. …”
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Regulation of gene expression under high hydrostatic pressure: the versatile role of the master regulator SurR in energy metabolism by Yann Moalic, Toan Bao Hung Nguyen, Jordan Hartunians, Tiphaine Birien, Axel Thiel, Mohamed Jebbar

“…Overall, our findings indicate that hydrostatic pressure shapes SurR function in T. barophilus, reflecting its adaptive plasticity in extreme environments.…”
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Chaotic Secure Communication Systems with an Adaptive State Observer by Wei-Der Chang, Shun-Peng Shih, Chih-Yung Chen

“…Therefore, in order to achieve this purpose, a state observer will be designed and its function is to estimate full system states only by using the system output signals. …”
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