Microbial Metabolite Effects on Vasculogenic Mimicry in Metastatic Cancers by Mohammad Kamalabadi Farahani, Aisa Bahar, Hamed Tahmasebi, Valentyn Oksenych, Mojdeh Jahantigh

“…Aggressive cancer cells can form new, functional blood vessel-like structures independently of endothelial cells, known as vasculogenic mimicry (VM), instead of the usual tumor blood vessel formation process. …”
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Astrocytes: Therapeutic targets for stroke by Jingxiu Li, Keyuan Gao, Lili Wang, Jiayue Wang, Mian Qin, Xinrui Wang, Kai Lian, Chao Li, Shan’e Gao, Chenxi Sun

“…In this comprehensive review, we initially provide an overview of the fundamental physiological functions of astrocytes in the brain, emphasizing their critical role in modulating neuronal homeostasis, synaptic activity, and blood–brain barrier integrity. …”
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Probiotic peptidoglycan skeleton enhances vaccine efficacy against MRSA by inducing trained immunity via the TLR2/JAK-STAT3 pathway by Lingdi Niu, Lingdi Niu, Haoyuan Duan, Jiaqing Wang, Zheng Jia, Hai Li, Junjie Guo, Shuhe Zhang, Ning Liu, Yaxin Miao, Junwei Ge, Fang Wang

“…Transcriptome analysis suggests that BLP may induce trained immunity by activating the IL-6-JAK-STAT3 pathway through TLR2 receptor activation, thereby modulating macrophage metabolic reprogramming and function. …”
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Muscle-homing peptides modified biomimetic curcumin nanoparticles ameliorate skeletal muscle dysfunction in aging mice by Jianjie Xie, Zongyu Huang, Nana Gao, Huicong Feng, Biaobiao Wang, Shuang Gao, He Tian, Chao Wu, Chang Liu

“…This study provides a therapeutic target of inflammatory and myogenic factors to improve the function of aging skeletal muscle, which provides valuable insights for the subsequent treatment of aging-related skeletal muscle function. …”
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Diffusion kurtosis imaging biomarkers associated with amelioration of neuroinflammation, gray matter microstructural abnormalities, and gut dysbiosis by central thalamic deep brain... by Lalitha Palanivelu, You-Yin Chen, Yao-Wen Liang, Ssu-Ju Li, Ching-Wen Chang, Yu-Ting Huang, Yu-Chun Lo

“…These findings support CTN-DBS as a safe and efficacious therapeutic strategy to reduce neuroinflammation, restore gray matter circuit function, and improve gut microbial composition in ASD via MGB axis modulation. …”
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Phase Noise Suppression Algorithm Based on Modified LLR Metric in SC-FDMA System by Zijie Xu, Guangliang Ren

“…Based on this model, we derive a closed-form expression of the likelihood function of the received symbol and calculate more accurate LLR information. …”
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Fibroblast activation protein and the tumour microenvironment: challenges and therapeutic opportunities by Hsing Hwa Lee, Zeyad Al-Ogaili

“…There are complex interactions between FAP-positive CAFs and various components of the immune system, highlighting their impact on T cell function and macrophage polarisation. This makes FAP a promising target for cancer therapy and potentially as a biomarker for immunotherapy treatment response. …”
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Research on noise suppression of electronic water pumps based on HRCSVPWM by HU Xinyang, MA Xipei, LIU Jie, FAN Pingqing

“…Secondly, the sawtooth wave period function was combined to increase the weakening effect on the pulse width modulation (PWM) harmonic amplitude. …”
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UAVAI-YOLO: dense small target detection algorithm based on UAV aerial images by HE Zhiqian, CAO Lijie

“…Finally, Wise-IoU was used to replace the original loss function to improve the accuracy of the model target detection frame. …”
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Research and Developments of Heterogeneous Catalytic Technologies by Milan Králik, Peter Koóš, Martin Markovič, Pavol Lopatka

“…Emphasis is placed on the fundamental interactions between reactants, solvents, and heterogeneous catalysts—specifically the roles of catalytic centers and support materials (e.g., functional groups) in modulating activation energies and stabilizing catalytic functionality. …”
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Glycosyltransferases: glycoengineers in human milk oligosaccharide synthesis and manufacturing by Alanna S. Slater, Alanna S. Slater, Andrew G. McDonald, Rita M. Hickey, Gavin P. Davey

“…This review provides an in-depth analysis of glycosyltransferases, beginning with their classification based on structural and functional characteristics. The catalytic activity of these enzymes is explored, highlighting the mechanisms by which they facilitate the precise addition of monosaccharides in HMO biosynthesis. …”
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Role of N6-methyladenosine methyltransferase component RBM15 in cancer progression and its therapeutic potential by Wenxiang Shen, Yulong Ma, Chunwang Yang, Shishun Yan, Kaishan Ye

“…This study endeavors to elucidate the structural characteristics and functional roles of RBM15, investigate its potential regulatory mechanisms across diverse tumors, uncover its distinct functions in tumor genesis, progression, and metastasis, and evaluate the therapeutic potential of targeting RBM15 in cancer treatment.…”
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Extracellular microRNAs initiate immunostimulation via activating toll-like receptor signaling pathways by Hongwei Liang, Koby Kidder, Yuan Liu

“…Abstract Since the discovery of the stability of extracellular microRNAs (miRNAs) in plasma and other body fluids about a decade ago, an increasing body of literature has addressed the function of extracellular miRNAs as novel regulators of gene expression. …”
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Decoding multicellular interaction networks–a new horizon in tumor microenvironment research by Roi Balaban, Merav Cohen

“…The tumor microenvironment (TME) milieu directs a plethora of tumor‐modulating functions. Recent years have seen pivotal breakthroughs in our understanding of the TME's role in tumor initiation and progression, with tangible clinical applications. …”
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Fusion of multi-scale and context for small target detection algorithm of unmanned aerial vehicle rescue by LIU Yuan, ZHAO Jing, JIANG Guoping, XU Fengyu, LU Ningyun

“…Finally, balance L1 loss was used to optimize the loss function of the baseline algorithm and enhance the stability of the model during the process of detection. …”
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Implementation and performance analysis of real time PPP software based on GAMP by Liu Ya, He Wentao, Zhang Jie

“…Aiming at the problem that GAMP software lacks the function of real-time precise point positioning at this stage, this paper analyzes and studies the principle and process of the post precise point positioning algorithm in the software, compares the different data sources and processing methods of the real-time and post precise point positioning, and combines with the processing method of existing real-time data processing software. …”
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Generative Adversarial Network-Based Distortion Reduction Adapted to Peak Signal-to-Noise Ratio Parameters in VVC by Weihao Deng, Zhenglong Yang

“…Furthermore, the perceptual function LPIPS loss is increased to align the image restoration effect more closely with human perception. …”
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Design and Implementation of a Hybrid-Driven Soft Robot by Ke Zhang, Yongqi Bi, Ruiyu Zhang

“…The hardware of the robot system is designed, a bending motion model is proposed, and SOFA framework is used to carry out finite element simulation (FEM) to verify the reasonableness of the design; linear motion speeds of up to 0.5 m/s, higher than the existing soft robots investigated, were verified experimentally separately after carrying the new module, and steering ability was retained; and the robot carrying the navigation module is verified to have a certain map building and localization function through the construction of the simultaneous localization and mapping (SLAM) experimental platform. …”
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Molecular mechanism of allosteric communication in Hsp70 revealed by molecular dynamics simulations. by Federica Chiappori, Ivan Merelli, Giorgio Colombo, Luciano Milanesi, Giulia Morra

“…By identifying the dynamically responsive protein regions and specific cross-domain hydrogen-bonding patterns that differentiate Hsp70 from Hsp110 as a function of the nucleotide, we propose a molecular mechanism for the allosteric signal propagation of the ATP-encoded conformational signal.…”
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Role of diet, physical activity and new drugs in the primary management of cancer cachexia in gastrointestinal tumors – a comprehensive review by Ester Oneda, Alessandra Manno, Silvia Noventa, Michela Libertini, Sara Cherri, Alberto Zaniboni

“…Targeted dietary strategies, such as a high-protein diet enriched with omega-3 and branched-chain amino acids (BCAAs), have proven effective in counteracting muscle loss and modulating inflammatory metabolism. Physical activity, particularly resistance training, contributes to preserving lean mass and improving physical function. …”
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