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7861
Inelastic Electron Tunneling Spectroscopy of Aryl Alkane Molecular Junction Devices with Graphene Electrodes
Published 2025-05-01“…The observed IETS spectra exhibit distinct peaks corresponding to the vibrational modes of the sandwiched aryl alkane molecules, and all major features are assigned through density functional theory calculations of molecular vibrational modes. …”
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7862
Leveraging Digital Library to Enhance Research and Learning Experience of College Students: An In-Depth Study
Published 2022-01-01“…Thus, the digital library provides a platform to assist students to develop an inclination towards learning and emotional shaping. Its functional system thus serves both comprehensive and harmonious development of students. …”
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7863
Immunological microenvironment and targeted therapeutics in multiple sclerosis: new insights in crosstalk between immune niches and CNS
Published 2025-08-01“…., T/B cells, myeloid cells and microglia) in disease progression, highlighting their functional heterogeneity across different MS subtypes. …”
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7864
Toll-like receptor 1/2 activation reduces immunoglobulin free light chain production by multiple myeloma cells in the context of bone marrow stromal cells and fibronectin.
Published 2025-01-01“…Toll-like receptor (TLRs) activation in multiple myeloma (MM) cells induces heterogeneous functional responses including cell growth and proliferation, survival or apoptosis. …”
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7865
Alternative Splicing of Barley Clock Genes in Response to Low Temperature.
Published 2016-01-01“…We identify changes in AS of various barley core clock genes including the barley orthologues of Arabidopsis AtLHY and AtPRR7 which showed the most pronounced AS changes in response to low temperature. The AS events modulate the levels of functional and translatable mRNAs, and potentially protein levels, upon transition to cold. …”
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7866
Targeting Caveolin-1 for enhanced rotator cuff repair: findings from single-cell RNA sequencing
Published 2025-03-01“…Abstract Rotator cuff injury (RCI), a prevalent cause of shoulder pain and disability, often leads to significant functional impairments due to adipocyte infiltration into the damaged tissue. …”
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7867
In Vivo Imaging of Retinoic Acid Receptor Activity using a Sodium/Iodide Symporter and Luciferase Dual Imaging Reporter Gene
Published 2004-07-01“…To visualize the intranuclear responses of functional retinoic acid receptors, we have developed a dual-imaging reporter gene system based on the use of sodium/iodide symporter (NIS) and luciferase in cancer cell lines. …”
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7868
Beyond Tumors: The Pivotal Role of TRIM Proteins in Chronic Non-Tumor Lung Diseases
Published 2025-02-01“…These include the dual functional nature of TRIM proteins, their context-dependent roles, the complexity of their downstream signaling networks, and the limitations of current therapeutic strategies in achieving tissue-specific targeting with minimal off-target effects. …”
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7869
Identification of an Epigenetic Signature for Coronary Heart Disease in Postmenopausal Women’s PBMC DNA
Published 2022-01-01“…After that, we used functional epigenetic module analysis and Cytoscape to remove the hub genes from the protein–protein interaction networks. …”
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7870
Revolutionizing consumer insights: the impact of fMRI in neuromarketing research
Published 2024-07-01“…Abstract This study performs a comprehensive bibliometric (performance analysis) and thematic content analysis of global research in "neuromarketing or consumer neuroscience" and "functional magnetic resonance imaging or fMRI." Utilizing the PRISMA framework and R package software, we analyzed thirty-six Scopus-indexed articles. …”
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7871
Supraspinal facilitation of painful stimuli by glutamatergic innervation from the retrosplenial to the anterior cingulate cortex.
Published 2025-01-01“…Although the projections from the RSC to the ACC have been found, the specifics of the synaptic connections and the functional implications of the RSC-ACC projections remain less understood. …”
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7872
Instability-induced crystal self-assembly in film-substrate system for the construction of large-area micro- and nano-chiral structures
Published 2025-07-01“…These chiral structures further demonstrate programmable wettability modulation for surface engineering applications. This study deciphers mechanisms of supramolecular chirality generation and cross-scale transmission while providing a controllable paradigm for constructing mesoscopic/macroscopic chiral systems, advancing functional chiral material design.…”
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7873
Theoretical Prediction of the Impact of Phosphorus Doping on the Elastic Constants of Silicon
Published 2025-06-01“…The Goodwin–Skinner–Pettifor functional form was applied to estimate dopant-induced stress potentials and their effect on lattice stiffness. …”
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7874
The microbiota, the malarial parasite, and the mice—a three-sided relationship
Published 2025-06-01“…Meanwhile, Plasmodium infection induces decreased microbial diversity and functional pathway deviation in murine microbiota, exacerbating host immunometabolic imbalance. …”
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7875
Unraveling Charge Transfer Mechanisms in Graphene–Quantum Dot Hybrids for High-Sensitivity Biosensing
Published 2025-04-01“…We demonstrate that PL quenching and its recovery are primarily driven by charge transfer, as evidenced by an unchanged fluorescence lifetime upon quenching. Density functional theory calculations reveal a significant charge redistribution at the graphene–QD interface, corroborating experimental observations. …”
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7876
Laforin, a dual specificity phosphatase involved in Lafora disease, is present mainly as monomeric form with full phosphatase activity.
Published 2011-01-01“…In the current study, we investigated the functional and physiological relevance of laforin dimerization. …”
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7877
KSHV manipulates Notch signaling by DLL4 and JAG1 to alter cell cycle genes in lymphatic endothelia.
Published 2009-10-01“…Here, we describe the mechanism through which KSHV directly modulates the expression of the Notch ligands JAG1 and DLL4 in lymphatic endothelial cells. …”
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7878
Rule-based cell systems model of aging using feedback loop motifs mediated by stress responses.
Published 2010-06-01“…Investigating the complex systems dynamics of the aging process requires integration of a broad range of cellular processes describing damage and functional decline co-existing with adaptive and protective regulatory mechanisms. …”
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7879
DNA methylation abnormalities in atherosclerosis
Published 2019-12-01“…In this review, we focus on recent achievements in the functional and description interpretation of the DNA methylation pattern of cells and tissues implicated in atherosclerosis. …”
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7880
Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension.
Published 2013-01-01“…The defects range from severe reduction of motor axon extension as observed in the dorsal forelimb to shortening of presynaptic branches of the phrenic nerve, as observed in the diaphragm. Molecular functional analysis showed that in the context of the spinal cord Ark2C enhances transcriptional responses of the Smad1/5/8 effectors, which are activated (phosphorylated) downstream of Bone Morphogenetic Protein (BMP) signals. …”
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