Subunits of the Drosophila actin-capping protein heterodimer regulate each other at multiple levels. by Ana Rita Amândio, Pedro Gaspar, Jessica L Whited, Florence Janody

“…We propose that the ability of the α and β subunits to control each other's levels assures that a pool of functional heterodimer is produced in sufficient quantities to restrict the development of tumor but not in excess to sustain normal tissue growth.…”
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Host long non-coding RNAs during bacterial infection by Abha Sahni, Sanjeev K. Sahni

“…Host lncRNAs play a pivotal role during bacterial infections, influencing cellular pathways to orchestrate a robust defense. Unraveling their functional mechanisms and therapeutic potential is crucial for advancing our understanding. …”
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The Role of Nanoparticle Elasticity on Biological Hydrogel Penetration by Chathuri I. Sodimanage, Marc Schneider

“…This review examines biological hydrogels’ structural and functional features as diffusion barriers, provides an overview of particle elasticity, key elasticity measurement techniques, and explores strategies for elasticity modulation in nanoparticles, such as composition, crosslinking density, and structural design. …”
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Fundamentals of muscle training of the horse: New paradigms for sports medicine specialists by José Luis López Rivero

“…As the main purpose of training is to modulate the muscular physiology according to the functional demands of each sporting discipline, it seems reasonable that those who in practice direct the training of the horse should know the fundamentals of these adaptations. …”
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Discovery of mosquito saliva microRNAs during CHIKV infection. by Payal D Maharaj, Steven G Widen, Jing Huang, Thomas G Wood, Saravanan Thangamani

“…Mosquito saliva is a complex concoction of many secretory factors that modulate the feeding foci to enhance pathogen infection and establishment. …”
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Co-transmission of neuropeptides and monoamines choreograph the C. elegans escape response. by Jeremy T Florman, Mark J Alkema

“…While co-transmission can increase the flexibility of cellular communication, understanding the functional impact on neural dynamics and behavior remains a major challenge. …”
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Primary cilia and inflammatory response: unveiling new mechanisms in osteoarthritis progression by Yuyan Sun, Ziyu Luo, Yuanyuan Fu, ThaiNamanh Ngo, Wen Wang, Yuanrong Wang, Ying Kong

“…This inflammatory response accelerates the progression of OA and contributes to pain and functional impairment. Primary cilia play a crucial role in cellular signal transduction and the maintenance of cartilage matrix homeostasis, and their dysfunction is closely linked to inflammatory responses. …”
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Sage extract and ascorbic acid derivative inhibit melanogenesis via downregulating keratinocyte-derived GM-CSF. by Hirokazu Kubo, Mariko Moriyama, Saya Goto, Yuko Miyake, Maki Nakamura, Yuki Ozeki, Yukio Nakamura, Hiroyuki Moriyama

“…Salvia officinalis (sage) extract has demonstrated potential as a functional ingredient for skin care application. However, its effect and mechanism in regulating skin pigmentation remain largely unclear. …”
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MYC Promotes LDHA Expression through MicroRNA-122-5p to Potentiate Glycolysis in Hepatocellular Carcinoma by Xiaofei Wang, Penghua Zhang, Ke Deng

“…In conclusion, the MYC/miR-122-5p/LDHA axis modulates glycolysis in HCC cells and possibly affects HCC progression.…”
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BASIC INTRACELLULAR MECHANISMS OF FORMATION OF MORPHOLOGICAL CHANGES OF INTERNAL ORGANS IN FLUOROSIS (LITERATURE REVIEW) by Мария Сергеевна Бугаева, Олег Иванович Бондарев

“…The indicated pathological processes mediate the formation of morphological changes and functional failure of both the musculoskeletal system and non-skeletal tissues, which requires a comprehensive approach to the treatment of fluoride intoxication and methods of its prevention.…”
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Mutant Huntingtin Does Not Affect the Intrinsic Phenotype of Human Huntington's Disease T Lymphocytes. by James R C Miller, Ulrike Träger, Ralph Andre, Sarah J Tabrizi

“…In contrast to the innate immune system, the intrinsic phenotype of T lymphocytes does not appear to be affected by the presence of mutant huntingtin, with Huntington's disease T lymphocytes exhibiting no significant functional differences compared to control cells. The transcriptional profile of T lymphocytes also does not appear to be significantly affected, suggesting that peripheral immune dysfunction in Huntington's disease is likely to be mediated primarily by the innate rather than the adaptive immune system. …”
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Inhibition of Migration of SW-480 Cells Induced by Royal Jelly Due to Reduction of β-Catenin by Milena Jovanović, Dragana Šeklić

“…These findings underscore the potential of RJ as a functional food to regulate colorectal cancer cell motility through modulation of β-catenin, thereby reducing disease aggressiveness.…”
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Anticancer Properties of Macroalgae: A Comprehensive Review by Sara Frazzini, Luciana Rossi

“…Among these, macroalgae have garnered significant attention due to their functional properties, which make them interesting in therapeutic applications, including cancer treatment. …”
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DPSTCN: Dynamic Pattern-Aware Spatio-Temporal Convolutional Networks for Traffic Flow Forecasting by Zeping Dou, Danhuai Guo

“…Spatially, the model constructs static and dynamic pattern-aware convolutions, leveraging geographical and area-functional information to effectively capture intricate spatial patterns, including dynamics and heterogeneity. …”
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PTPN11 in cartilage development, adult homeostasis, and diseases by Wentian Yang, Véronique Lefebvre

“…It promotes RAS/MAPK signaling downstream of receptor tyrosine kinases, cytokine receptors, and extracellular matrix proteins, and was shown in various lineages to modulate cell survival, proliferation, differentiation, and migration. …”
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Cellular and Molecular Mechanisms Underlying Transcranial Magnetic Stimulation: Experimental Data for Evaluating Changes in Nervous Tissue by Anna P. Krasilnikova, Anna V. Egorova, Dmitry N. Voronkov, Alexandra G. Poydasheva, Valeria V. Glinkina, Vladimir S. Sukhorukov

“…The aim of this review was to evaluate and summarize new experimental data on the fundamental mechanisms underlying the action of TMS and its potential in modulating structural and functional changes in nervous tissue. …”
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Optoelectronic control of surface plasmon polaritons at metal-doped semiconductor interfaces by Raj K Vinnakota, Mayra M Schliemann, Shaimum Shahriar

“…We present a metal–semiconductor (M–S) based electro-optic modulator designed for functional plasmonic circuits, utilizing the active control of surface plasmon polaritons (SPPs) at M–S junction interfaces. …”
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Targeting EZH2 in Cancer: Mechanisms, Pathways, and Therapeutic Potential by Maria Saveria Gilardini Montani, Rossella Benedetti, Mara Cirone

“…Enhancer of zeste homolog 2 (EZH2) is a methyltransferase involved in cell cycle regulation, cell differentiation, and cell death and plays a role in modulating the immune response. Although it mainly functions by catalyzing the tri-methylation of H3 histone on K27 (H3K27), to inhibit the transcription of target genes, EZH2 can directly methylate several transcription factors or form complexes with them, regulating their functions. …”
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Lactylation and viral infections: A novel link between metabolic reprogramming and immune regulation. by Shanshan Chen, Tongxue Qin, Shengrui Luo, Fengyi Wang, Feirong Chen, Hailun Wei, Yuting Wu, Rongfeng Chen, Wudi Wei, Jingzhen Lai, Hao Liang, Li Ye, Zongxiang Yuan, Junjun Jiang

“…Post-translational modifications (PTMs) regulate protein structure, function, and interactions, playing pivotal roles in cellular processes and disease progression. …”
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Optimal tuning of bacterial sensing potential by Anand Pai, Lingchong You

“…Abstract Through production and sensing of small signal molecules, quorum sensing (QS) enables bacteria to detect changes in their density and regulate their functions accordingly. QS systems are tremendously diverse in terms of their specific sensory components, the biochemical and transport properties of signaling molecules, their target functions and the context in which QS‐mediated functions are activated. …”
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