Showing 7,641 - 7,660 results of 14,318 for search '(functional OR function) modules', query time: 0.25s Refine Results
  1. 7641

    Growth arrest and DNA damage-inducible 45: a new player on inflammatory diseases by Yanmei Ma, Yanmei Ma, Yanmei Ma, Md Munnaf Hossen, Md Munnaf Hossen, Md Munnaf Hossen, Jennifer Jin Huang, Zhihua Yin, Zhihua Yin, Jing Du, Zhizhong Ye, Zhizhong Ye, Miaoyu Zeng, Miaoyu Zeng, Zhong Huang, Zhong Huang

    Published 2025-02-01
    “…Growth arrest and DNA damage-inducible 45 (GADD45) proteins are critical stress sensors rapidly induced in response to genotoxic/physiological stress and regulate many cellular functions. Even though the primary function of the proteins is to block the cell cycle, inhibit cell proliferation, promote cell apoptosis, and repair DNA damage to cope with the damage caused by internal and external stress on the body, evidence has shown that GADD45 also has the function to modulate innate and adaptive immunity and plays a broader role in inflammatory and autoimmune diseases. …”
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  2. 7642

    Balanced CoQ6 biosynthesis is required for lifespan and mitophagy in yeast by I. González-Mariscal, A. Martín-Montalvo, C. Ojeda-González, A. Rodríguez-Eguren, P. Gutiérrez-Ríos, P. Navas, C. Santos-Ocaña

    Published 2017-02-01
    “…In yeast its biosynthesis depends on a multiprotein complex in which Coq7 protein has both catalytic and regulatory functions. Coq7 modulates CoQ6 levels through a phosphorylation cycle, where dephosphorylation of three amino acids (Ser/Thr) by the mitochondrial phosphatase Ptc7 increases the levels of CoQ6. …”
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  3. 7643

    Arthropod autophagy molecules facilitate Anaplasma phagocytophilum infection of Ixodes scapularis tick cells by Jeremy W. Turck, Hameeda Sultana, Girish Neelakanta

    Published 2025-03-01
    “…RNAi-mediated knockdown of shp-2 or functional blocking with SHP-2 inhibitor resulted in significantly increased bacterial burden and reduced phospho-mTOR levels in A. phagocytophilum-infected tick cells. …”
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  4. 7644

    Differential aging of growth plate cartilage underlies differences in bone length and thus helps determine skeletal proportions. by Julian C Lui, Youn Hee Jee, Presley Garrison, James R Iben, Shanna Yue, Michal Ad, Quang Nguyen, Bijal Kikani, Yoshiyuki Wakabayashi, Jeffrey Baron

    Published 2018-07-01
    “…Here, we show evidence that these functional, structural, and molecular senescent changes occur earlier in the growth plates of smaller bones (metacarpals, phalanges) than in the growth plates of larger bones (femurs, tibias) and that this differential aging contributes to the disparities in bone length. …”
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  5. 7645

    Mechanosensitive Piezo channels in mineralized tissues: emerging roles in osteodental adaptation and disease by Junchi Dong, Ran Li, Yuhuang Chen, Guixin Zhu, Xing Liang

    Published 2025-07-01
    “…They detect and respond to mechanical forces via mechanosensitive Piezo channels, modulating physiological and pathological processes. …”
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  6. 7646

    The emerging roles of platelet-derived extracellular vesicles in disease by Can Lou, Xiaohong Cai

    Published 2025-12-01
    “…Their role in cellular signal transduction is examined, and their functional properties are compared with other platelet-derived products such as platelet-rich plasma.Results pEVs show potential as both therapeutic agents and diagnostic biomarkers. …”
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  7. 7647

    Neural Network Underlying Recovery from Disowned Bodily States Induced by the Rubber Hand Illusion by In-Seon Lee, Younbyoung Chae

    Published 2016-01-01
    “…We used functional magnetic resonance imaging to investigate how causal influences between brain regions during the rubber hand illusion (RHI) are modulated by tactile and visual stimuli. …”
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  8. 7648

    Understanding quality of life in Danish women with metastatic breast cancer undergoing multiple treatments by Helle Pappot, Annasofie Jørgensen, Anna Hincheli Bjørum, Christina Bøgh Jakobsen, Camilla Uhre Jørgensen, Beverley Lim Høeg, Pernille Bidstrup, Ann Knop, Line Bentsen

    Published 2025-02-01
    “…QoL, symptoms, and daily life function were measured using the European Organization for Research and Treatment of Cancer (EORTC) core questionnaire (QLQ-C30) and the breast cancer module (BR45). …”
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  9. 7649
  10. 7650

    Insight on the complete process of photoacoustic generation and propagation of cerebrovascular in brain via multi-physics coupling method by Shangkun Hou, Anzhi Lv, Jiabin Lin, Bokang You, Shuaixin Huang, Xianlin Song

    Published 2025-01-01
    “…This visualization study provides theoretical guidance for the research and application of photoacoustic imaging in brain structural and functional imaging.…”
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  11. 7651

    Design of Stable Controller for Flexible Solar Panel by H∞ Loop-Shaping Method by Dini Wang, Fanwei Meng, Shengya Meng, Aiping Pang

    Published 2020-01-01
    “…We adopt H∞ loop-shaping design and put forward a directive method for selecting the weighting function. The simulation results indicate that system bandwidth is optimized based on the stable controller. …”
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  12. 7652

    Hawking-Page and entanglement phase transition in 2d CFT on curved backgrounds by Akihiro Miyata, Masahiro Nozaki, Kotaro Tamaoka, Masataka Watanabe

    Published 2024-08-01
    “…By means of conformal mapping we study the equivalent system on flat space governed by the deformed Hamiltonian, which is a spatial integral of the Hamiltonian density modulated by an enveloping function. Focusing on holographic CFTs, we observe Hawking-Page like phase transition for the thermal and the entanglement entropy as we vary the background metric. …”
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  13. 7653

    Psychological and Biological Aspects of “Without-Body Bereavement”: Reflections at COVID-19 Pandemic Time by Francesco Franza, Alba Cervone, Barbara Solomita, Wilma Di Napoli, Maurilio Tavormina, Giuseppe Tavormina

    Published 2024-01-01
    “…Furthermore, some biological and neurological processes that modulate and allow for the mourning process will be synthesized.…”
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  14. 7654

    Molecular Action of Lenalidomide in Lymphocytes and Hematologic Malignancies by Jessica M. McDaniel, Javier Pinilla-Ibarz, P. K. Epling-Burnette

    Published 2012-01-01
    “…Although treatment with lenalidomide has translated into a significant extension in overall survival in MM and MDS and has superior safety and efficacy relative to thalidomide, the mechanism of action as it relates to immune modulation remains elusive. Based on preclinical models and clinical trials, lenalidomide, as well as other structural thalidomide derivatives, enhances the proliferative and functional capacity of T-lymphocytes and amplifies costimulatory signaling pathways that activate effector responses and suppress inflammation. …”
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  15. 7655

    Analytically Explicit Results for the Distribution of the Number of Customers Served during a Busy Period for Special Cases of the M/G/1 Queue by M. L. Chaudhry, Veena Goswami

    Published 2019-01-01
    “…This paper presents analytically explicit results for the distribution of the number of customers served during a busy period for special cases of the M/G/1 queues when initiated with m customers. The functional equation for the Laplace transform of the number of customers served during a busy period is widely known, but several researchers state that, in general, it is not easy to invert it except for some simple cases such as M/M/1 and M/D/1 queues. …”
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  16. 7656

    Exploring the role of unconventional T cells in rheumatoid arthritis by Tangqing Xu, Hao Cai, Jianye Liu, Xingxing Mao, Yulong Chen, Minhao Chen, Youhua Wang

    Published 2025-08-01
    “…NKT, MAIT, and γδ T cells contribute to the amplification of inflammatory responses and joint tissue destruction through diverse mechanisms, exhibiting unique tissue tropism and functional plasticity. Recently, novel therapeutic strategies have been developed to target these subsets, including modulation of antigen presentation pathways, inhibition of pro-inflammatory signaling cascades, and reprogramming of cellular functionalities. …”
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  17. 7657
  18. 7658

    Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation by Jiawei Huang, Qingwen Deng, Lai Ling Tsang, Guozhu Chang, Jinghui Guo, Ye Chun Ruan, Chi Chiu Wang, Gang Li, Hon Fai Chan, Xiaohu Zhang, Xiaohua Jiang

    Published 2025-02-01
    “…The PEGDA/SA/Col-I hydrogel supports MSC viability and function offering a promising scaffold for DFU treatment. …”
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  19. 7659

    Naringenin and SMER28 target lysosomal reformation and rescue SPG11 and SPG15 hereditary spastic paraplegia phenotypes by Chiara Vantaggiato, Giulia Guarato, Francesca Brivio, Elena Panzeri, Beatrice Speltoni, Sentiljana Gumeni, Genny Orso, Filippo Maria Santorelli, Maria Teresa Bassi

    Published 2025-08-01
    “…Our work indicates that lysosomal reformation is a good strategy for herditary spastic parapegia forms with impaired lysosomal function and identifies naringenin as new modulator of this process, offering further hand to planning phase II clinical trials in SPG11-SPG15 patients.…”
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  20. 7660

    Does the presence of only specific active sites control the switch of selectivity from C1 to C2+ products in CO2RR? by Angela Mercedes Ronsisvalle, Daniele Giusi, Mario Samperi, Chiara Genovese, Siglinda Perathoner, Gabriele Centi, Claudio Ampelli

    Published 2025-10-01
    “…By analysing Faradaic selectivity as a function of applied potential across CuO nanoplate samples with different wettability, we observe a transition from 100 % C2+ selectivity to 100 % C1 selectivity, with the potential threshold for this switch dependent on wettability. …”
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