Cystatin F-a key player in central nervous system disease by Yi-Ting Wang, Qiang Li, Jun-Chao Liu, Chen Chen, He-Xuan Ding, Xu Zha, Ke Zhang

“…It has several unique characteristic structures that determine some of its specific functions. Cystatin F is expressed predominantly in peripheral immune cells and in the microglia of the central nervous system (CNS). …”
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Exploring the oncogenic role and prognostic value of CKS1B in human lung adenocarcinoma and squamous cell carcinoma by Md. Solayman Hossain, Tariqul Islam Tusar, Nairita Ahsan Faruqui, Tanjim Ishraq Rahaman, Yasin Arafath Sharker, Shimran Saharia Santo, Abu Tayab Moin, Yusha Araf, Ibrahim Khalil Afif, Shoaib Saikat, Mohammad Jakir Hosen

“…Functional enrichment analysis highlighted its involvement in critical oncogenic pathways, including cell cycle regulation and immune modulation.DiscussionThe results suggest that CKS1B serves as a potential biomarker for early detection and prognosis in NSCLC. …”
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Application of MCKD-cyclic Domain Demodulation Method in Gearbox Fault Diagnosis by Wang Zhijian, Wang Junyuan, Zeng Zhiqiang, Zhang Jiping

“…Firstly,the strong background noise of the original signal is decreased by the MCKD method in order to extract the interest period component,the above given signal is processed by the cyclic autocorrelation function demodulation. The new method can decrease the cross- term interference caused by multi- modulator and multi- carrier and improve the reliability of the analysis. …”
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Switching Characteristic of HiPak 6.5 kV IGBT and the Influence of Gate Unit by Makan Chen, Raffael Schnell

“…It presented the investigation on the reverse recovery of ABB HiPak 6 500 V/750 A IGBT module. For the first time, the forward recovery and the reverse recovery of diode and its anti-parallel connected IGBT were researched as a function of di/dt, and the impact on IGBT module was analyzed. …”
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Genome-wide identification and molecular characterization of the MAPK family members in sand pear (Pyrus pyrifolia) by Yue Xu, Huiying Wang, Haiyan Shi

“…Although the importance of this family has been extensively studied in other plants, the precise composition and functional mechanisms of MAPK members in sand pear remain elusive. …”
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Regulation of Inflammatory Responses by Pulsed Electromagnetic Fields by Amr Kaadan, Simona Salati, Ruggero Cadossi, Roy Aaron

“…Mechanistically, PEMFs act via adenosine receptors, specifically A_2A, which play a key role in inflammation modulation and tissue repair. In some clinical trials, PEMF has yielded short-term symptom relief and functional improvements in early-stage osteoarthritis patients, arthroscopy patients, and anterior cruciate ligament reconstruction patients.…”
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齿根过渡曲线优化方法研究 by 芮井中, 吴志学

“…The goal is to obtain optimal fillet curve for minimum bending stress using parameterized geometry models.The boundary shape for fillet curve is described by generalized elliptic function.Thus it becomes very easy to describe and obtain optimal fillet curve just making use of the optimization module provided in a commercial finite element package due to the less number of design variables.The gear model is founded by ANSYS,and adopting first step optimization in ANSYS optimize the maximum Von Mises stress of tooth root.As compared to the known solutions in the literature,it was shown that extremely good results could be obtained while using the proposed parameterized equations.…”
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The VDAC3/DHODH Axis Ameliorates Sepsis-induced Myocardial Injury by Regulating Ferroptosis by Jiali Wang, Fan Zhang, Chaoqing Tan, Nana Wang, Xuexia Xia, Yun Ye, Yue Cao, Xin Huang, Zhenjiang Bai, He Zhao, Ling Sun, Qiuqin Xu, Huiting Zhou, Jie Huang

“…This study aimed to explore the function and mechanism of VDAC3 in SIMI pathogenesis, with a particular emphasis on its regulatory role in ferroptosis. …”
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The Dynamic Interactions of m6A Modification and R-Loops: Implications for Genome Stability by Nicholas Kim, Hong Sun

“…Here, we discuss the reported functions of various m6A regulatory proteins in relation to R-loops, highlighting their distinct roles in recognizing and modulating the formation, stability, and resolution of these structures. …”
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Metabolism-associated marker gene-based predictive model for prognosis, targeted therapy, and immune landscape in ovarian cancer: an integrative analysis of single-cell and bulk RN... by Lele Ling, Bingrong Li, Boliang Ke, Yinjie Hu, Kaiyong Zhang, Siwen Li, Te Liu, Peng Liu, Bimeng Zhang

“…Methods Single-cell RNA sequencing (scRNA-seq) data related to OC were analyzed using AUCell scores to identify subpopulations at the single-cell level. The “AddModuleScore” function of the “Seurat” package was adopted to score and select marker genes from four gene sets: glycolysis metabolism, lipid metabolism, choline metabolism, and sphingolipid metabolism. …”
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Dehydrodiisoeugenol alleviates palmitate-induced mitochondrial dysfunction in human vascular smooth muscle cells through the activation of SIRT1-mediated Drp1 deacetylation by Jianjun Zhao, Zhiyun Shu, Xiangjun Li, Wenqing Zhang, Mengze Sun, Wenxiao Song, Hongyuan Cheng, Shaomin Shi

“…Methods A PA-induced high-fat model of VSMCs was established, and the effect of PA on the VSMCs on function was detected by evaluating the oxidative stress and apoptosis of cells, as well as mitochondrial function. …”
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The effect of transcranial direct current stimulation on the interplay between executive control, behavioral variability and mind wandering: A registered report by Andreas Alexandersen, Gábor Csifcsák, Josephine Groot, Matthias Mittner

“…Additionally phasic pupil size also showed a tendency to be increased during periods of high executive function use. Importantly, none of the EEG or pupil measures were modulated by HD-tDCS. …”
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Therapeutic role of gut microbiota in lung injury-related cognitive impairment by Yanxia Cheng, Guangtao Hu, Lin Deng, Yalan Zan, Xia Chen

“…It can also relieve lung injury and therapeutically modulate brain function and behavior. This perspective provides a new idea for the follow-up treatment of lung injury-related cognitive impairment caused by dysregulation of gut microbiota.…”
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MCPIP3 orchestrates the balance of epidermal proliferation and differentiation by Agata Lichawska-Cieslar, Weronika Szukala, Pawel Pilat, Leopold Eckhart, Jacek C Szepietowski, Jolanta Jura

“…Conclusions The MCPIP3 protein modulates the balance of keratinocyte proliferation and differentiation and functions as a regulator of epidermal morphology in vivo.…”
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Moving impedance profiles make one-way, spectrum-reshaping mirrors by Mingjie Li, S. A. R. Horsley

“…We find a set of exact solutions to Maxwell's equations in spacetime-varying materials, where the refractive index is constant, while the impedance exhibits effective motion, i.e., it is a function of x−vt. We find that waves copropagating with the modulation are not reflected within the material, while counterpropagating waves are continually reflected by the changing impedance. …”
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Design of Topology and Parameters of Interleaved Double Buck Single-phase Rectifier by Jingwen AI, Qing DING, Yinghan GAO, Fen TANG, Yibing TONG

“…The double buck rectifier can directly realize single-stage buck rectification, and has power decoupling function, which can suppress the secondary ripple in the DC side. …”
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Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expression by Shengze Yao, Yesu Jeon, Barry Kesner, Jeannie T Lee

“…The target genes are diverse in function but are unified by their active chromatin status. …”
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Acupuncture mediates the “gut–testis axis” to improve asthenozoospermia by Jianheng Hao, Jianheng Hao, Huichao Xu, Boya Chang, Jia Ren, Haijun Wang, Laixi Ji, Laixi Ji

“…Furthermore, reproductive function improvements in asthenozoospermic mice through acupuncture were achieved via an FMT.ConclusionAcupuncture may alleviate asthenozoospermia symptoms by modulating the gut–testis axis and repairing the gut–testis barrier.…”
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Light regulates the synthesis and accumulation of plant secondary metabolites by Wenyuan Wu, Huan Wu, Rentao Liang, Shiping Huang, Luxiao Meng, Miao Zhang, Miao Zhang, Miao Zhang, Miao Zhang, Fengfeng Xie, Fengfeng Xie, Fengfeng Xie, Fengfeng Xie, Hua Zhu, Hua Zhu, Hua Zhu, Hua Zhu

“…The findings may offer an insight for enhancing bioactive compounds in medicinal plants and developing functional agricultural products.…”
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Symmetry-adapted Markov state models of closing, opening, and desensitizing in α 7 nicotinic acetylcholine receptors by Yuxuan Zhuang, Rebecca J. Howard, Erik Lindahl

“…Recent studies have resolved and functionally annotated closed, open, and desensitized states of these receptors, providing insight into ion permeation and lipid binding. …”
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