Species-specific gene regulatory network rewiring mediated by the GATA-type regulator NsdD in Aspergillus by Heungyun Moon, Mi-Kyung Lee, Junha Shin, Sung Chul Park, Julio C. Rivera Vazquez, Daniel Amador-Noguez, Nancy P. Keller, Hee-Soo Park, Kap-Hoon Han, Jae-Hyuk Yu

“…In this study, we systematically dissect the regulatory functions of NsdD, a highly conserved GATA-type TF in Pezizomycotina, using network-based multi-omics approaches in two distantly related species, A. nidulans and A. flavus. …”
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Study of Urban Rail Train Renewable Braking Energy Feedback System by JI Hui, LI Kunpeng, YI Yunlan

“…In order to verify the function and reliability of urban rail train renewable energy feedback system, mathematical model of energy feedback converter with double-loop control strategy and SVPWM modulation was built, and the simulation and test were brought out. …”
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IDH1 regulates human erythropoiesis by eliciting chromatin state reprogramming by Mengjia Li, Hengchao Zhang, Xiuyun Wu, Mengqi Yu, Qianqian Yang, Lei Sun, Wei Li, Zhongxing Jiang, Fumin Xue, Ting Wang, Xiuli An, Lixiang Chen

“…However, the function and mechanism of IDH1 in human erythropoiesis still remains unclear. …”
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Intraarticular gold for knee osteoarthritis: An ancillary analysis of biomarkers and outcome of a pilot study by Sten Rasmussen, Christopher Aboo, Jacob Skallerup, Allan Stensballe

“…Clinical outcome measures at inclusion, 8 weeks, and 2 years, were the PainDetect questionnaire, WOMAC pain, stiffness, and function. In addition, Quantitative Sensory Testing, Pain Pressure Threshold, Temporal Summation, Conditioned Pain Modulation, and pain diary were assessed at inclusion and after 8 weeks. …”
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Design and Implementation of Football Player Training Management System Based on Intelligent Image by Yang Sun, Changjun Hu

“…The overall architecture of the system, and the detailed design of each functional module of the system. It mainly includes football player information management module, football player training plan viewing module, training goal formulation module and training information feedback module. …”
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Rumen DNA virome and its relationship with feed efficiency in dairy cows by Xiaohan Liu, Yifan Tang, Hongyi Chen, Jian-Xin Liu, Hui-Zeng Sun

“…The study annotated 2,382 auxiliary metabolic genes (AMGs), comprising 1,752 lytic virus-associated AMGs across 51 functional categories and 589 temperate virus-associated AMGs across 29 categories. …”
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Microgravity and Human Body: Unraveling the Potential Role of Heat-Shock Proteins in Spaceflight and Future Space Missions by Olga Maria Manna, Stefano Burgio, Domiziana Picone, Adelaide Carista, Alessandro Pitruzzella, Alberto Fucarino, Fabio Bucchieri

“…Previous studies have demonstrated that long-term exposure to microgravity during spaceflight can cause various changes in the human body, such as muscle atrophy, changes in muscle fiber composition, cardiovascular function, bone density, and even immune system functions. …”
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Mechanistic Insights Into Qidan Yixin Decoction for Diabetic Cardiomyopathy via Macrophage Polarization by Yi Liu, Juan Zhang, Wei Gao, Quancheng Han, Yitao Xue, Xiujuan Liu

“…Conclusion: QDYXD improves cardiac function in DCM by attenuating M1 macrophage polarization and inhibiting the HIF-1 signaling pathway, specifically through the modulation of PGK1, LDHA, and HIF1A. …”
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The role of mycoplasmas as an infectious agent in carcinogenesis by M. A. Galyamina, O. V. Pobeguts, A. Yu. Gorbachev

“…Mycoplasmas are of particular interest because they have unique abilities to readily attach to and enter eukaryotic cells, modulate their functional state, and induce chronic inflammation while evading the host’s immune system. …”
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miRNA‐221 and miRNA‐222 induce apoptosis via the KIT/AKT signalling pathway in gastrointestinal stromal tumours by Michaela Angelika Ihle, Marcel Trautmann, Helen Kuenstlinger, Sebastian Huss, Carina Heydt, Jana Fassunke, Eva Wardelmann, Sebastian Bauer, Hans-Ulrich Schildhaus, Reinhard Buettner, Sabine Merkelbach-Bruse

“…In gastrointestinal stromal tumours (GISTs) expression of miR‐221 and miR‐222 is reduced compared to control tissue and other sarcomas but the functional effects of this downregulation are not fully understood. …”
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mTOR-related linc-PMB promotes mitochondrial biogenesis via stabilizing SIRT1 mRNA through binding to the HuR protein by Chen Qian, Zhang Huaying, Wang Daokun, Liao Wenjing, Liu Yazhou, Cai Yurui, Wang Siyou, Yu Mengqian

“…Collectively, our findings reveal a novel regulatory pathway in which linc-PMB, through its interaction with HuR, modulates the SIRT1/PGC-1α/mtTFA axis to maintain mitochondrial biogenesis and function.…”
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Cascade-Gain-Switching for Generating 3.5-<inline-formula><tex-math notation="LaTeX">$\mu$</tex-math> </inline-formula>m Nanosecond Pulses From Monolithic Fiber Lasers by Jianlong Yang, Haizhe Zhong, Shuaiyi Zhang, Yulong Tang, Dianyuan Fan

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Identification of SNPs in the second intron of IGF2BP1 and their Association with growth traits in Nanjiang Yellow goat by Shuheng Chen, Liang Xu, Junchen Leng, Zitong Chen, Yu. Chen, Li. Li, Hongping Zhang, Mingzhou Li, Jiaxue Cao

“…Seven SNPs were mapped to the conserved region of the second intron, necessitating further investigation into their functional relevance and association with growth traits. …”
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TRPV4 activation by TGFβ2 enhances cellular contractility and drives ocular hypertension by Christopher Nass Rudzitis, Monika Lakk, Ayushi Singh, Sarah N Redmon, Denisa Kirdajová, Yun-Ting Tseng, Michael L De Ieso, W Daniel Stamer, Samuel Herberg, David Krizaj

“…Here, we employed molecular, optical, electrophysiological, and tonometric strategies to establish the role of TGFβ2 in transcription and functional expression of mechanosensitive channel isoforms alongside studies of TM contractility in biomimetic hydrogels and intraocular pressure (IOP) regulation in a mouse model of TGFβ2-induced OHT. …”
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Polarization Reconstruction Study of Wide Field-of-view Photoelectric Polarimeter for POLAR-2/LPD by Zu-Ke Feng, Hong-Bang Liu, Di-Fan Yi, Li-Rong Xie, Cong Dai, Huan-Bo Feng, Jian-Chao Sun, Jiang He, Yuan-Hao Wang, Rui-Ting Ma, Bin-Long Wang, Qian-Nan Mai, Jiang-Chuan Tuo, Qian Zhong, Zhen-Yu Tang, Qian Liu, Fei Xie, Shuang-Nan Zhang, En-Wei Liang

“…It was found that the reconstruction of the emission azimuthal angles of photoelectron tracks is the main factor affecting the shape of the modulation function for off-axis radiation. Therefore, a modulation function correction method based on Monte Carlo (MC) simulation is proposed. …”
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Semantic Segmentation Method for High-Resolution Tomato Seedling Point Clouds Based on Sparse Convolution by Shizhao Li, Zhichao Yan, Boxiang Ma, Shaoru Guo, Hongxia Song

“…In order to reduce the number of parameters so as to further improve the inference speed, the SpConv module is designed to function through the residual concatenation of the skeleton convolution kernel and the regular convolution kernel. …”
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Infrared Aircraft Detection Algorithm Based on High-Resolution Feature-Enhanced Semantic Segmentation Network by Gang Liu, Jiangtao Xi, Chao Ma, Huixiang Chen

“…This paper constructs an infrared aircraft detection algorithm based on a high-resolution feature-enhanced semantic segmentation network which combines the location attention feature fusion network, the hybrid atrous spatial pyramid pooling module, the dice loss function, and a network that maintains the resolution of feature maps. …”
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SR-YOLO: Spatial-to-Depth Enhanced Multi-Scale Attention Network for Small Target Detection in UAV Aerial Imagery by Shasha Zhao, He Chen, Di Zhang, Yiyao Tao, Xiangnan Feng, Dengyin Zhang

“…Finally, the model’s detection performance for small targets is improved by utilizing the Normalized Wasserstein Distance loss function to optimize the Complete Intersection over Union loss function. …”
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Burden of cystic fibrosis in children by Kathryn Bresnick, Emilio Arteaga-Solis, Stefanie J Millar, Glen Laird, Cecile LeCamus

“…The burden of illness (BOI) in children with CF is incompletely characterised, particularly as it relates to CFTR genotypes prior to the availability of the first CFTR modulators. This retrospective, cross-sectional, descriptive study evaluated the BOI in US children with CF &lt;12 years of age prior to the first approval of CFTR modulators.Methods Data from the US Cystic Fibrosis Foundation Patient Registry from 2011 were used to summarise key patient and disease characteristics using descriptive statistics, overall and grouped by age (0 to &lt;2 years, 2 to &lt;6 years and 6 to &lt;12 years) and genotype (F508del/F508del, F508del/minimal function (MF), MF/MF, gating mutation on ≥1 allele, residual function mutation on ≥1 allele and R117H on ≥1 allele) group.Results The analysis included 9185 children. …”
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Lipofilling—A Regenerative Alternate for Remodeling Burn Scars: A Clinico-Immunohistopathological Study by Bhojani Jatin, Durga Karki, Charanjeet Ahluwalia, Vamseedharan Muthukumar, Divyanjali Karki

“…Scar tissue can cause functional limitations, cosmetic impairments, pain, and itch. …”
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