EGRN-YOLO: An Enhanced Multi-View Remote Sensing Detection Algorithm for Onshore Wind Turbines Based on YOLOv7 by Renzheng Xue, Haiqiang Xu, Qianlong Wu

“…Finally, the NWD loss function is introduced to replace the CIoU loss function, thereby improving the accuracy of positive and negative sample allocation for small targets. …”
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Cell non-autonomous signaling through the conserved C. elegans glycoprotein hormone receptor FSHR-1 regulates cholinergic neurotransmission. by Morgan Buckley, William P Jacob, Letitia Bortey, Makenzi E McClain, Alyssa L Ritter, Amy Godfrey, Allyson S Munneke, Shankar Ramachandran, Signe Kenis, Julie C Kolnik, Sarah Olofsson, Milica Nenadovich, Tanner Kutoloski, Lillian Rademacher, Alexandra Alva, Olivia Heinecke, Ryan Adkins, Shums Parkar, Reesha Bhagat, Jaelin Lunato, Isabel Beets, Michael M Francis, Jennifer R Kowalski

“…Intestine-specific knockdown of FSHR-1 reduces neuromuscular function, indicating FSHR-1 is both necessary and sufficient in the intestine for its neuromuscular effects. …”
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Histone modifications and metabolic reprogramming in tumor-associated macrophages: a potential target of tumor immunotherapy by Yiting Xu, Han Zhang, Dengyun Nie

“…Histone modifications, including methylation, acetylation, lactylation, phosphorylation, ubiquitination, SUMOylation, ADP-ribosylation, and crotonylation, critically regulate tumor-associated macrophages (TAMs) polarization by modulating gene expression and functional states. Reprogramming TAMs from M2 to M1 phenotypes through epigenetic targeting has emerged as a promising strategy to enhance anti-tumor immunity and improve the efficacy of cancer immunotherapy. …”
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Design and Implementation of Intelligent Control Garbage Bin by Li-Fen Tu, Qi Peng, Rongpan Deng

“…Aiming at the problem that it was difficult to popularize accurate garbage sorting and delivery, a kind of intelligent garbage bin that is more intelligent, efficient, and functional than the traditional garbage bin was designed and manufactured. …”
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4D Biofabrication of Magnetically Augmented Callus Assembloid Implants Enables Rapid Endochondral Ossification via Activation of Mechanosensitive Pathways by Konstantinos Ioannidis, Andreas Dimopoulos, Isaak Decoene, Maya Guilliams, Hanna Svitina, Liudmyla Storozhuk, Rodrigo de Oliveira‐Silva, Sergey Basov, Nguyen Thi Kim Thanh, Stefanos Mourdikoudis, Margriet J. Van Bael, Bart Smeets, Dimitrios Sakellariou, Ioannis Papantoniou

“…Abstract The use of magnetic‐driven strategies for non‐contact manipulation of engineered living modules opens up new possibilities for tissue engineering. …”
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Ellagic Acid Alleviates Imidacloprid-Induced Thyroid Dysfunction via <i>PI3K/Akt/mTOR</i>-Mediated Autophagy by Amina A. Farag, Mahmoud Mostafa, Reham M. Abdelfatah, Alshimaa Ezzat ELdahshan, Samar Fawzy Gad, Shimaa K. Mohamed, Mona K. Alawam, Aya Aly Elzeer, Nesma S. Ismail, Sally Elsharkawey, Haneen A. Al-Mazroua, Hatun A. Alomar, Wedad S. Sarawi, Heba S. Youssef

“…Conversely, EA improved thyroid function and ameliorated histopathological alterations by enhancing autophagy-inducing pathways. …”
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ROS‐Responsive Microneedle Patches Enable Peri‐Lacrimal Gland Therapeutic Administration for Long‐Acting Therapy of Sjögren's Syndrome‐Related Dry Eye by Jingqing Mu, Xiangyu Ding, Yapeng Song, Baoyue Mi, Xiaolong Fang, Baihua Chen, Bin Yao, Xuguang Sun, Xiaoyong Yuan, Shutao Guo, Xia Hua

“…Herein, a ROS‐responsive microneedle patch with detachable functionality (CE‐MN) is developed to enable straightforward and minimally invasive administration to the lacrimal gland area by penetrating the periocular skin. …”
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Neuroimaging and Emotional Development in the Pediatric Population: Understanding the Link Between the Brain, Emotions, and Behavior by Giuseppe Marano, Maria Benedetta Anesini, Miriam Milintenda, Mariateresa Acanfora, Claudia Calderoni, Francesca Bardi, Francesco Maria Lisci, Caterina Brisi, Gianandrea Traversi, Osvaldo Mazza, Roberto Pola, Gabriele Sani, Eleonora Gaetani, Marianna Mazza

“…This narrative scoping review synthesizes current pediatric neuroimaging evidence, filling a gap in the literature by integrating structural, functional, and emerging modalities, to provide clear translational pathways for clinical and behavioral observations. …”
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Nonlinear phenomena make animal calls alarming for human listeners by Anna Terrade, Mathilde Massenet, Lise Pernel, Nicolas Mathevon, Andrey Anikin, David Reby

“…Summary: Animal vocalizations are extremely diverse, and evolutionary approaches to understanding this diversity assume some mapping between their acoustic form and communicative function, with specific features serving universal roles. …”
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Choroid plexus-mediated CSF secretion remains stable in aging rats via high and age-resistant metabolic activity by Sara D. Lolansen, Eszter O. Révész, Søren N. Andreassen, Marleen Trapp, Chiara Salio, Marco Sassoé-Pognetto, Jens Velde Andersen, Emil W. Westi, Trine L. Toft-Bertelsen, Jonathan H. Wardman, Anne-Kristine Meinild Lundby, Flemming Dela, Annarita Patrizi, Blanca I. Aldana, Nanna MacAulay

“…Here, we resolve age-dependent modulation of CSF dynamics and choroid plexus function by complementary in vivo determinations of intracranial pressure (ICP) and CSF secretion/absorption rates, combined with transcriptomic, morphological, and metabolic analysis of choroid plexus in aging male rats. …”
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Improved CAR internalization and recycling through transmembrane domain optimization reduces CAR-T cytokine release and exhaustion by Shufeng Xie, Shufeng Xie, Jinlan Long, Ruiheng Wang, Ruiheng Wang, Rufang Xiang, Rufang Xiang, Huajian Xian, Yixin Wang, Weiyu Dou, Wenjie Zhang, Dan Li, Ting Kang, Zhihong Chen, Zhihong Chen, Chunjun Zhao, Zhenshu Xu, Han Liu

“…Through co-culture with tumor cells, we evaluate CAR dynamic change, activation levels, exhaustion markers, mitochondrial function, and differentiation in both CAR-T cells. …”
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Scavenger Receptors and Their Potential as Therapeutic Targets in the Treatment of Cardiovascular Disease by Sam L. Stephen, Katie Freestone, Sarah Dunn, Michael W. Twigg, Shervanthi Homer-Vanniasinkam, John H. Walker, Stephen B. Wheatcroft, Sreenivasan Ponnambalam

“…One approach is using gene therapy to modulate scavenger receptor function in atherosclerosis. …”
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Environmental justice index and prevalence of asthma and COPD in US neighborhoods- a population-based studyResearch in context by Sumanth Khadke, Vidhatri Khadke, Ashish Kumar, Bhargav Makwana, Sourbha S. Dani, Sadeer Al-Kindi, Sanjay Rajagopalan, Yixin Kong, Khurram Nasir, Gary Adamkiewicz, Anju Nohria, Timothy N. Liesching, Sarju Ganatra, Victor Pinto-Plata

“…Multivariable quasi-Poisson regression with an offset function was used to compare covariate-adjusted risk ratios of health indicators across quartiles of neighborhood socio-environmental burden. …”
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ROMO1 overexpression protects the mitochondrial cysteinome from oxidations in aging by Fengli Xu, Haipeng Huang, Kun Peng, Chongshu Jian, Hao Wu, Zhiwen Jing, Shan Qiu, Ying Chen, Keke Liu, Ling Fu, Yanru Wang, Jing Yang, Xiaotao Duan, Chu Wang, Heping Cheng, Xianhua Wang

“…Here we show that ROS modulator 1 (ROMO1), a small inner mitochondrial membrane protein, plays a role in protecting the mitochondrial cysteinome. …”
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Research progress on the regulatory effects of probiotics and their metabolites on intestinal homeostasis in piglets by SONG Mengzhen, LI Jingjing, LI Jiaxuan, TAO Shiyu

“…Probiotics and their metabolites are important for piglet growth and development as they exert beneficial effects by enhancing intestinal barrier function and modulating the host immune response. This paper summarized the regulation of intestinal barrier functions by probiotics and the impact of probiotic metabolites on intestinal homeostasis in piglets, and the effects and mechanisms of probiotics and their metabolites on the regulation of intestinal homeostasis in piglets were comprehensively discussed, aiming to provide a theoretical reference for the application of probiotics in regulating the intestinal health of piglets.…”
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Fluorinated hydroxyapatite conditions a favorable osteo-immune microenvironment via triggering metabolic shift from glycolysis to oxidative phosphorylation by Kaidi Chen, Seongmin Ha, Leyao Xu, Chengwu Liu, Yuanxiang Liu, Xiayi Wu, Zhipeng Li, Shiyu Wu, Bo Yang, Zhuofan Chen

“…RNA-seq analysis suggested that the polarization-regulating function of FPHA may be related to changes in cellular metabolism. …”
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Ginsenoside Rb₁ Ameliorates Heart Failure Ventricular Remodeling by Regulating the Twist1/PGC-1α/PPARα Signaling Pathway by Ziwei Zhou, Zhimin Song, Xiaomeng Guo, Qi Wang, Meijing Li, Minyu Zhang, Muxin Gong

“…<b>Results:</b> Ginsenoside Rb₁ can restore cardiac function in HF rats, improve mitochondrial function, alleviate energy metabolism disorders, and inhibit ventricular remodeling. …”
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Porphyromonas gingivalis affects neutrophil pro-inflammatory activities by Agnieszka Zimny, Alicja Płonczyńska, Alicja Płonczyńska, Wiktor Jakubowski, Natalia Zubrzycka, Natalia Zubrzycka, Jan Potempa, Jan Potempa, Maja Sochalska

“…Although gingipains are the major virulence factor of the pathogen, their role in impairing apoptosis and immune cell function is not fully understood. To investigate the impact of gingipains on neutrophil viability and function, we conducted studies using murine HoxB8 neutrophils and primary human neutrophils infected with wild-type strains of Porphyromonas gingivalis (W83 and ATCC 33277), or a gingipains-null mutant with deleted gingipains encoding genes, or wild-type bacteria preincubated with specific gingipain inhibitors. …”
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Design and synthesis of 1,4,8-triazaspiro[4.5]decan-2-one derivatives as novel mitochondrial permeability transition pore inhibitors by Valentina Albanese, Gaia Pedriali, Martina Fabbri, Antonella Ciancetta, Silvia Ravagli, Chiara Roccatello, Remo Guerrini, Giampaolo Morciano, Delia Preti, Paolo Pinton, Salvatore Pacifico

“…The mitochondrial permeability transition pore (mPTP), a multiprotein platform including structural components of ATP synthase with putative gate function, is an emerging pharmacological target that could be modulated to facilitate the restoration of organ function after a hypoxic insult. …”
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Validating an IoT implementation framework for supporting industry 4.0 in SMEs: a Delphi and focus group approach by Qusay Adnan Abdulaziz, Hazilah Mad Kaidi, Maslin Masrom, Khairur Rijal Jamaludin, Shamsul Sarip, Suha Ibraheem Hamad, Halim Shah Hamzah

“…Despite recognizing the framework's comprehensiveness, experts highlighted the need for improved functionality and real-time performance, while expressing concerns about complexity. …”
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