Transcriptome analysis of multiple tissues and identification of tissue-specific genes in Lueyang black-bone chicken by Pan Li, Yufei Yang, Bo Ning, Yingmin Tian, Ling Wang, Wenxian Zeng, Hongzhao Lu, Tao Zhang

“…MGs were closely associated with tissue-specific physiological functions, providing valuable insights into the molecular mechanisms governing tissue functionality. …”
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SUMOylation of TP53INP1 is involved in miR-30a-5p-regulated heart senescence by Yi-Xiang Hong, Chan Wu, Jing-Zhou Li, Fei Song, Yu Hu, Yue Han, Yi-Jie Mao, Wei-Yin Wu, Yan Wang, Gang Li

“…Abstract Heart senescence is critical for cardiac function. This study aimed to characterize the role and mechanism of action of miR-30a-5p in cardiac senescence. miR-30a-5p was downregulated in aged mouse hearts and neonatal rat cardiomyocytes (NRCMs). …”
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Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways. by Charlie W Lees, William J Zacharias, Mark Tremelling, Colin L Noble, Elaine R Nimmo, Albert Tenesa, Jennine Cornelius, Leif Torkvist, John Kao, Susan Farrington, Hazel E Drummond, Gwo-Tzer Ho, Ian D R Arnott, Henry D Appelman, Lauri Diehl, Harry Campbell, Malcolm G Dunlop, Miles Parkes, Sarah E M Howie, Deborah L Gumucio, Jack Satsangi

“…Reduced GLI1 function predisposes to a heightened myeloid response to inflammatory stimuli, potentially leading to IBD.…”
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Rho-Associated Kinase Inhibitor Fasudil Protects from Sepsis-Induced Acute Kidney Injury in Rat via Suppressing STAT-3 and NLRP-3 Pathway by Neslihan Şahin, Ejder Saylav Bora, Osman Sezer Çınaroğlu, Oytun Erbaş

“…Kidney function markers, including BUN and creatinine, showed marked improvement. …”
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Exhale-Focused Thermal Image Segmentation Using Optical Flow-Based Frame Filtering and Transformer-Aided Deep Networks by Do-Kyeong Lee, Jae-Sung Shin, Jae-Sung Choi, Min-Hyung Choi, Min Hong

“…To redress this, we propose a thermal imaging-based framework for respiratory segmentation aimed at estimating non-invasive pulmonary function. The proposed method uses an optical flow magnitude-based thresholding technique to automatically extract exhalation frames and segment them into frame sequences. …”
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Efficacy of ginkgo biloba extract in the treatment of idiopathic pulmonary fibrosis: a systematic review and meta-analysis of randomized controlled trials by Xuxin Sun, Ling Peng, Wenchao Xiao, Keying Li, Sheng Chen

“…Additionally, there was a significant reduction in arterial carbon dioxide partial pressure, interleukin-4, hyaluronan, and laminin levels.ConclusionGBE may offer therapeutic benefits in IPF by improving respiratory function, modulating inflammation, and affecting fibrosis markers. …”
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Research Progress on the Protective Effects of Active Components of Huangqi (Astragali Radix) on Pancreatic β-Cells by Liyi Yan, Zhenhua Li, Yuan Chen

“…Furthermore, Huangqi (Astragali Radix) can promote β-cell proliferation by modulating dedifferentiation and transdifferentiation, improve the islet microenvironment by regulating immune function and reducing M1 macrophage polarization, and may delay β-cell senescence. …”
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Subtilases: a major prospect to the genome editing in horticultural crops by Umashankar Chandrasekaran, Umashankar Chandrasekaran, Woo Jong Hong, Hyeran Kim, Hyeran Kim

“…However, current knowledge about SBTs is largely limited to ‘in vitro cleavage assays,’ with few studies exploring loss of function analyses for more in depth characterization. …”
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High-Performance YOLOv5s: Traffic Sign Detection Algorithm for Small Target by Mengxia Hu, Shengwen Pi, Jinying Zhou, Xinming Wan, Qiaoshou Liu

“…Finally, we replace the original corrected intersection over union (CIOU) loss function with inner-shape intersection over union (Inner-SIOU) loss function, which improves both the training speed and accuracy of the model. …”
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Pro-Fibrotic Macrophage Subtypes: SPP1+ Macrophages as a Key Player and Therapeutic Target in Cardiac Fibrosis? by Moritz Uhlig, Sebastian Billig, Jan Wienhold, David Schumacher

“…These interventions have effectively reduced fibrosis and improved cardiac function in animal models. The mechanisms underlying SPP1+ macrophage function in cardiac fibrosis provide a foundation for innovative therapies aimed at mitigating pathological remodeling and improving outcomes in patients with heart failure. …”
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Gut Microbiome rewiring via fecal transplants: Uncovering therapeutic avenues in Alzheimer’s disease models by Prabhat Upadhyay, Sudhir Kumar, Anurag Tyagi, Aayush Raj Tyagi, Tarun Barbhuyan, Sarika Gupta

“…Conclusion Targeted modulation of the gut microbiome through strategies like FMT may offer potential benefits in Alzheimer’s disease by influencing neuroinflammation, oxidative stress, and cognitive function. …”
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PPARG in Human Adipogenesis: Differential Contribution of Canonical Transcripts and Dominant Negative Isoforms by M. Aprile, M. R. Ambrosio, V. D'Esposito, F. Beguinot, P. Formisano, V. Costa, A. Ciccodicola

“…The existence of different PPARG variants suggests that alternative splicing is crucial to modulate PPARγ function, underlying some underestimated aspects of its regulation. …”
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SKGRec: A Semantic-Enhanced Knowledge Graph Fusion Recommendation Algorithm with Multi-Hop Reasoning and User Behavior Modeling by Siqi Xu, Ziqian Yang, Jing Xu, Ping Feng

“…A relationship-aware aggregation module is designed to dynamically integrate higher-order relational features in the knowledge graph through the attention scoring function. …”
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Imaging performance of a CaWO4/CMOS sensor by Niki Martini, Vaia Koukou, George Fountos, Ioannis Valais, Ioannis Kandarakis, Christos Michail, Athanasios Bakas, Eleftherios Lavdas, Konstantinos Ninos, Georgia Oikonomou, Lida Gogou, George Panayiotakis

“…The aim of this study was to investigate the modulation transfer function (MTF) and the effective gain transfer function (eGTF) of a non-destruc­­tive testing (NDT)/industrial inspection complementary metal oxide semi­conductor (CMOS) sensor in conjunction with a thin calcium tungstate (CaWO4) screen. …”
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Propagation of the main signal in a dispersive Lorentz medium by A. Ciarkowski

“…The signal propagating in the medium is excited by a sine-modulated pulse signal, with its envelope described by a hyperbolic tangent function. …”
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Exosomes derived from a mesenchymal-like endometrial regenerative cells ameliorate renal ischemia reperfusion injury through delivery of CD73 by Bo Shao, Hong-da Wang, Shao-hua Ren, Qiang Chen, Zhao-bo Wang, Yi-ni Xu, Tong Liu, Cheng-lu Sun, Yi-yi Xiao, Hong-yu Jiang, Yi-cheng Li, Peng-yu Zhao, Guang-mei Yang, Xu Liu, Yu-fan Ren, Hao Wang

“…However, its immunosuppressive function in regulating purinergic metabolism has been largely neglected. …”
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MODELLING OF THE ALGORITHM FOR DEFINITION OF THE TOOTH CROWN'S COLOR SHADE BASED ON STM32F4XX SERIES MICROCONTROLLERS by P. A. Burdavitsyn, V. V. Shatalova

“…Here's a variant of implementation of the algorithm for definition of the tooth crown's color shade with adaptation’s function to external conditions based on stm32f4xx series microcontrollers and color sensor module TCS3200.…”
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Motor-based prediction mediates implicit vocal imitation by Yuchunzi Wu, Zhili Han, Xing Tian

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Cell cycle- and cancer-associated gene networks activated by Dsg2: evidence of cystatin A deregulation and a potential role in cell-cell adhesion. by Abhilasha Gupta, Daniela Nitoiu, Donna Brennan-Crispi, Sankar Addya, Natalia A Riobo, David P Kelsell, Mỹ G Mahoney

“…Our findings here offer a novel pathway of CSTA regulation involving Dsg2 and a potential crosstalk between Dsg2 and CSTA that modulates cell adhesion. These results further support the recent human genetic findings that loss of function mutations in the CSTA gene result in skin fragility due to impaired cell-cell adhesion: autosomal-recessive exfoliative ichthyosis or acral peeling skin syndrome.…”
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Mechanism of Insomnia After Stroke Based on Intestinal Flora by Wang Y, Pan L, Guan R

“…Numerous studies have emphasized the crucial function of intestinal flora in the pathological changes associated with insomnia after stroke. …”
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