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6981
Improving Performance of Integrated Ground-HAPS FSO Communication Links With MIMO Application
Published 2024-01-01“…Capitalizing on this PDF expression, we present novel results for fundamental performance metrics, including outage probability, average bit-error rate (BER) of on-off keying (OOK) modulation scheme, and ergodic capacity expressed in terms of the Meijer's G function. …”
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6982
Host species and temperature drive beech and Scots pine phyllosphere microbiota across European forests
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6983
Regulation of polyamine interconversion enzymes affects α-Synuclein levels and toxicity in a Drosophila model of Parkinson’s Disease
Published 2025-08-01“…Abstract Parkinson’s Disease (PD) is a neurodegenerative disorder characterized by α-synuclein accumulation and aggregation, leading to disrupted cellular homeostasis, impaired mitochondrial function, and neuroinflammation, ultimately causing neuronal death. …”
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6984
Research on data loss probability and its impact of CTCS-3 train ground communication based on GSM-R
Published 2014-12-01“…In order to solve the problem that Euroradio's safe functional module (SFM) of CTCS-3 train control system can not apply protective measures for time-related transmission risks,communication model and failure recovery model for transmission of CTCS-3 train control system are built which based on deterministic and stochastic Petri nets (DSPN).Combining the two models and using TimeNET 4.0 to simulate the result of data loss probability,a conclusion can be concluded that even considering that only data loss will cause dangerous of train control system,the result still can not meet the requirement of SIL4 based on the relevant specification for the CTCS-3.…”
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6985
circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes
Published 2025-08-01“…It also examines their subsequent effects on mitochondrial function and oxidative stress. H9c2 cardiomyocytes were subjected to H/R to model myocardial injury. …”
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6986
The Dectin-1 Receptor Signaling Pathway Mediates the Remyelination Effect of Lentinan through Suppression of Neuroinflammation and Conversion of Microglia
Published 2022-01-01“…Microglia rapidly respond to changes in the environment by altering morphotype and function during the progressive disease stage. Although substantial progress has been made in the drug development for MS, treatment of the progressive forms of the disease remains unsatisfactory. …”
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6987
A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development.
Published 2017-08-01“…We further showed that expression of Bmp4 in the ureteric mesenchyme depends on HH signaling and Foxf1, and that exogenous BMP4 rescued cell proliferation and epithelial differentiation in ureters with abrogated HH signaling or FOXF1 function. We conclude that SHH uses a FOXF1-BMP4 module to coordinate the cellular programs for ureter elongation and differentiation, and suggest that deregulation of this signaling axis occurs in human congenital anomalies of the kidney and urinary tract (CAKUT).…”
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6988
Role and mechanisms of histone methylation in osteogenic/odontogenic differentiation of dental mesenchymal stem cells
Published 2025-03-01“…Here is a concise overview of the pivotal functions of epigenetic histone methylation at H3K4, H3K9, and H3K27 in the regulation of osteo-/odontogenic differentiation and renewal of DMSCs in both non-inflammatory and inflammatory microenvironments. …”
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6989
The Impact of brain-gut microbiota composition on depression
Published 2024-11-01“…However, in the last decade, numerous studies have demonstrated the impact of gut bacteria dysbiosis on brain functions and, consequently, its role in the pathogenesis of depression. …”
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6990
Impacts of trace minerals (zinc, copper, and selenium) supplementation on pig’s health under different challenge models
Published 2025-08-01“…Various experimental models replicate challenges faced on commercial farms, in which Zn supports immune function by stabilizing cell membranes, modulating cytokine expression, and strengthening the intestinal barrier through increased synthesis of tight junction proteins, which collectively help reduce inflammation and pathogen translocation. …”
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6991
Brown and beige adipose tissue‐derived metabokine and lipokine inter‐organ signalling in health and disease
Published 2025-07-01“…Abstract Adipose tissue has an established endocrine function through the secretion of adipokines. However, a role for bioactive metabolites and lipids, termed metabokines and lipokines, is emerging in adipose tissue‐mediated autocrine, paracrine and endocrine signalling and inter‐organ communication. …”
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6992
Bacterial Colonization and the Development of Intestinal Defences
Published 2004-01-01“…Neither function exists in the germ-free state, but rapidly develops after conventionalization (colonization) of the germ-free animal. …”
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6993
Immune cell diversity and regenerative markers reveal interactions among macrophages, rodlet cells, and stem cells in the kidney of Poecilia sphenops
Published 2025-07-01“…Inflammatory markers IL-1β and NF-κB were highly expressed in rodlet cells and macrophages, respectively, suggesting their role in immune modulation. The expression of S100 protein in rodlet cells and acetylcholine in macrophages further highlights their specialized functions in immune regulation. …”
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6994
Genetic interaction profiles of regulatory kinases differ between environmental conditions and cellular states
Published 2020-05-01“…How signaling networks function to respond to diverse signals that result in cell cycle exit and establishment of a quiescent state is poorly understood. …”
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6995
Mitochondrial metabolism and cancer therapeutic innovation
Published 2025-08-01“…Within the tumor microenvironment, mitochondria profoundly impact immune responses by modulating T-cell survival and function, macrophage polarization, NK cell cytotoxicity, and neutrophil activation. …”
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6996
Effects of Brain-Derived Neurotrophic Factor on Local Inflammation in Experimental Stroke of Rat
Published 2010-01-01“…Exogenous BDNF significantly improved motor-sensory, sensorimotor function, and vestibulomotor function, while BDNF did not decrease the infarct volume. …”
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6997
发动机前端附件驱动系统静动态性能设计计算软件
Published 2013-01-01“…EFEAD-Kit software is an automated analysis tool for evaluating static and dynamic characteristics of Engine Front End Accessory Drive(EFEAD) system.Introduction of the program including static design module and dynamic design module is proposed firstly.Then the characteristics of user interface and the function of EFEAD-Kit software are described.Finally,a generic EFEAD system is taken as a studying example,and its static and dynamic performance are calculated using the software and are compared with experiment.…”
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6998
Palmitoylation in cardiometabolic diseases: From molecular mechanisms to clinical implications
Published 2025-10-01“…By modulating protein hydrophobicity, stability, subcellular localization, enzymatic activity, and membrane trafficking, palmitoylation exerts profound effects on cellular function. …”
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6999
Recirculation of digestive enzymes
Published 2011-06-01“…Enzymes, being switched off from circulation by recretion, are involved in gastro-intestinal digestion and carry out a signal role in modulation of secretory, motor and absorptive functions of the gut. …”
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7000
Thyroid Hormones and Metabolism Regulation: Which Role on Brown Adipose Tissue and Browning Process?
Published 2025-03-01“…Thyroid hormones (THs) are important modulators of many metabolic processes, being strictly associated with the control of energy balance, mainly through activities on the brain, white and brown adipose tissue, skeletal muscle, liver, and pancreas. …”
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