The Effect of Bioactive Compounds in Multiple Sclerosis as the Adjuvant Immunomodulatory: A Comprehensive Review by Mathiyazhagan Narayanan, N. Prabhu

“…Results: Bioactive substances have several advantageous effects, such as antioxidant activity, suppression of pro-inflammatory cytokines, and modulation of immune cell function. Numerous investigations substantiate their function in mitigating neuroinflammation and decelerating illness advancement. …”
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Dread and the disvalue of future pain. by Giles W Story, Ivaylo Vlaev, Ben Seymour, Joel S Winston, Ara Darzi, Raymond J Dolan

“…For a minority of individuals pain has maximum negative value at intermediate delay, suggesting that the dread function may itself be prospectively discounted in time. …”
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Hederagenin's uric acid-lowering effects in hyperuricemic mice: Mechanistic insights from molecular docking and in vivo analysis. by Ping Chen, Ya-Ni Tian, Jing-Tao Wang, Xiang-Lin Yin, Bao-Sheng Guan, Xue Bai

“…Serum uric acid (UA) levels, liver and kidney function indicators, XOD activity, and oxidative stress markers were assessed. …”
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Cell surface receptors for signal transduction and ligand transport: a design principles study. by Harish Shankaran, Haluk Resat, H Steven Wiley

“…We have constructed a generalized mathematical model of receptor-ligand binding and internalization to understand how receptor internalization dynamics encodes receptor function and regulation. A given signaling or transport receptor system represents a particular implementation of this module with a specific set of kinetic parameters. …”
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MicroRNA-133 inhibits behavioral aggregation by controlling dopamine synthesis in locusts. by Meiling Yang, Yuanyuan Wei, Feng Jiang, Yanli Wang, Xiaojiao Guo, Jing He, Le Kang

“…This study shows the novel function and modulation pattern of a miRNA in phenotypic plasticity and provides insight into the underlying molecular mechanisms of the phase transition of locusts.…”
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Dual-robot formation transport in random environment and narrow restricted area via improved DDPG navigation by Liang Tang, Ronggeng Ma, Bowen Chen, Yisen Niu

“…Specifically, the paper first optimizes the reward function module in the DDPG network to incorporate a decision-swapping reward mechanism for training the formation's navigation capability. …”
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Synaptic plasticity in fronto-insular circuits underlying stress susceptibility and resilience by Devin Rocks, Conor Liston

“…Converging lines of evidence indicate that these mechanisms may converge on the dysregulation of synaptic transmission in the anterior cingulate and anterior insula, disrupting motivation and hedonic function. In this review, we examine how chronic stress and antidepressants modulate synaptic connectivity in stress-sensitive brain circuits. …”
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Research on the Injection Mold Design and Molding Process Parameter Optimization of a Car Door Inner Panel by Kefan Yang, Youmin Wang, Guoqing Wang

“…We established the objective function model with gate position as the independent variable, and used a multi-population genetic algorithm to solve the optimal position of the function model to get the best gate position. …”
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FyTok: An integrated modeling simulator for magnetic confinement fusion Tokamak by Xiaojuan Liu, Zhi Yu

“…FyTok handles each of these separately using data bindings, formula bindings and function bindings. FyTok can be easily configured using configuration files to organise the different module classes, generate the required physical workflows, and track the evolution of physical quantities in the workflows for modeling purposes. …”
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THE SOLUTION TO THE EQUATION OF THE SHOCK WAVE BURGERS IN THE PTC MATHCAD ENVIRONMENT by R. E. Oleynikova

“…However, this error is detected through the values of the nonlinear term included in the differential equation, which is determined according to the binomial representation through the quadratic forms of the matrix of the trial function. These trends allow us to obtain an approximate solution from a limited number of members of the trial 92 function sufficient for accurate simulation of the solution in a wide range of Reynolds numbers characterizing the ratio of nonlinear and dissipative terms in the Navier - Stokes equation. …”
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ESCRT-0 is not required for ectopic Notch activation and tumor suppression in Drosophila. by Emiliana Tognon, Nadine Wollscheid, Katia Cortese, Carlo Tacchetti, Thomas Vaccari

“…Drosophila genes encoding ESCRT-I, -II, -III components function in sorting signaling receptors, including Notch and the JAK/STAT signaling receptor Domeless. …”
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In Search of Novel Targets for Heart Disease: Myocardin and Myocardin-Related Transcriptional Cofactors by Alexander T. Mikhailov, Mario Torrado

“…A close examination of the findings identifies the MYOCD-related transcriptional cofactors as putative therapeutic targets to improve cardiac function in heart failure conditions through distinct context-dependent mechanisms. …”
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Comprehensive Optimization of Dual Threshold Independent-Gate FinFET and SRAM Cells by Haiyan Ni, Jianping Hu, Huishan Yang, Haotian Zhu

“…In this paper, we proposed a comprehensive method to optimize the Dual Threshold (DT) IG FinFET devices by carrying out modulations for the gate electrode work function, oxide thickness, and silicon body thickness. …”
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Multistep Finite Control Set Model Predictive Control of Photovoltaic Power Generation System with Harmonic Compensation by Xuejiao Gong, Shifeng Hu, Ruijin Zhu

“…This paper proposes a PV power generation grid-connected system to improve power quality, with an active power filter (APF) function. Through the maximum power point tracking (MPPT) method, PV power generation can operate at the maximum power point and play the function of harmonic and reactive power compensation at the load side. …”
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Metabolites as regulators of autoimmune diseases by Maria Tada, Michihito Kono

“…Immune cell metabolism is essential for regulating immune responses, including activation, differentiation, and function. Through glycolysis and oxidative phosphorylation (OXPHOS), metabolism supplies energy and key intermediates for cell growth and proliferation. …”
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CTRP2 overexpression improves insulin and lipid tolerance in diet-induced obese mice. by Jonathan M Peterson, Marcus M Seldin, Stefanie Y Tan, G William Wong

“…Its in vivo metabolic function, however, has not been established. We show here that acute and chronic metabolic perturbations induced by fasting or high-fat feeding up-regulated the mRNA expression of Ctrp2 in white adipose tissue without affecting its circulating plasma levels. …”
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Active power compensation circuit for resonance mitigation and harmonic reduction in microgrid system by Rakan Khalil Antar, Basil Mohammed Saied

“…An active power compensation circuit (APCC) is proposed and designed to function with two categories of linear/non-linear loads. …”
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Fitness landscapes of human microsatellites. by Ryan J Haasl, Bret A Payseur

“…Microsatellites that are subject to selection include loci known to cause trinucleotide expansion disorders and modulate gene expression, as well as intergenic loci with no obvious function. …”
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A novel yeast-derived aldehyde-reducing compound MF001 protects against alcohol-induced liver damage. by Eun-Ho Lee, Min-Hee Seo, Soo-Young Park, Sulagna Mukherjee, Jae-Ho Lee, Sora Kang, Ji-Yu Lee, Namgyu Lee, Hung Taeck Kwon, Seung-Soon Im

“…Histological analysis revealed decreased hepatic lipid deposition and inflammation following MF001 administration. Furthermore, MF001 modulated alcohol metabolism by downregulating Cyp2e1 and Adh1, thereby decreasing acetaldehyde accumulation and improving liver function, as evidenced by normalized ALT and AST levels. …”
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Do they understand more? Turkish EFL speakers perception of sentence stress in English by Anita Buczek-Zawiła

“…It most typically signals details of an utterance information structure, but it also performs a contrastive or emphasizing function, thus expressing focus in the spoken discourse. …”
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