Circ_0008043 promotes the metastasis of hepatocellular carcinoma by regulating the miR-661/PLEKHG4B axis by Kangjun Zhang, Taishi Fang, Qijun Chen, Xu Yan, Xin Jin, Nan Ma

“…Although circ_0008043 is predicted to be highly expressed in HCC tissues, its functional role and molecular mechanisms remain poorly understood. …”
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Andrias davidianus bone peptides alleviates hyperuricemia-induced kidney damage in vitro and in vivo by Wei Li, Haihong Chen, Hongliang Chen, Ziyin Li, Wei Hu, Qinxuan Zhou, Bing Xu, Yi Wang, Xinhui Xing

“…Hyperuricemia (HUA) is a vital risk factor for chronic kidney diseases (CKD) and development of functional foods capable of protecting CKD is of importance. …”
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Exploring plant-microbe interactions in adapting to abiotic stress under climate change: a review by Ali Muhammad, Ali Muhammad, Xiangjun Kong, Shuaichao Zheng, Na Bai, Lijie Li, Muhammad Hafeez Ullah Khan, Sajid Fiaz, Zhiyong Zhang

“…Plants coexist with microorganisms, which play a significant role in influencing their growth and functional traits. The rhizosphere serves as an ecological niche encompassing plant roots and is a chemically complex environment that supports the growth and development of diverse plant-interactive microbes. …”
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Metabolic mapping of the human solute carrier superfamily by Tabea Wiedmer, Shao Thing Teoh, Eirini Christodoulaki, Gernot Wolf, Chengzhe Tian, Vitaly Sedlyarov, Abigail Jarret, Philipp Leippe, Fabian Frommelt, Alvaro Ingles-Prieto, Sabrina Lindinger, Barbara M G Barbosa, Svenja Onstein, Christoph Klimek, Julio Garcia, Iciar Serrano, Daniela Reil, Diana Santacruz, Mary Piotrowski, Stephen Noell, Christoph Bueschl, Huanyu Li, Gamma Chi, Stefan Mereiter, Tiago Oliveira, Josef M Penninger, David B Sauer, Claire M Steppan, Coralie Viollet, Kristaps Klavins, J Thomas Hannich, Ulrich Goldmann, Giulio Superti-Furga

“…Abstract Solute carrier (SLC) transporters govern most of the chemical exchange across cellular membranes and are integral to metabolic regulation, which in turn is linked to cellular function and identity. Despite their key role, individual functions of the SLC superfamily members were not evaluated systematically. …”
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Influence of Pregnancy on Whole-Transcriptome Sequencing in the Mammary Gland of Kazakh Mares by Zhenyu Zhang, Zhixin Lu, Xinkui Yao, Linling Li, Jun Meng, Jianwen Wang, Yaqi Zeng, Wanlu Ren

“…The results showed differential expression in 2136 mRNAs, 180 lncRNAs, 104 miRNAs, and 1162 circRNAs. Gene ontology functional annotation indicates that these differentially expressed genes are involved in multiple key biological processes, such as the cellular process (BP), metabolic process, and biological regulation. …”
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Microbiota-dependent metabolites – New engine for T cell warriors by Yang Tang, Anbo Fu, Liangjing Wang, Qiwei Ge

“…One of their most important roles is their regulatory effects on the immune system, particularly in shaping the development, differentiation, and function of T cells, which are key players in the adaptive immune response. …”
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Anomalous Reflection of Acoustic Waves in Air with Metasurfaces at Low Frequency by Huaijun Chen

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Tactile exploration and imagery elicit distinct neural dynamics in the parietal cortical network by Qi Zhang, Qi Zhang, Yang Yang, Zhemeng Wang, Zhemeng Wang, Jiayue Zhou, Jiayue Zhou, Runshi Gao, Xingyi Yang, Xingyi Yang, Siwei Li, Tao Yu, Jin Zhou, Changyong Wang, Changyong Wang

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miRNA-based regulation in growth plate cartilage: mechanisms, targets, and therapeutic potential by Prachi Thakore, Anne M. Delany

“…Demonstration that a human gain-of-function mutation in miR-140 causes skeletal dysplasia underscores the clinical relevance of understanding miRNA-mediated regulation. …”
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MORE FLORET1 Interacts with C-type Replication Protein A Complex and Regulates Male Meiosis in Rice by Lianjun Zhu, Rou Chen, Yu Huang, Guobin Liang, Jinwen Wu, Haibin Guo, Xiangdong Liu, Zijun Lu

“…Although the impact of MOF1 on floral organ development and its negative regulation of the key tapetal gene PKS2 have been established, the specific function of MOF1 in male meiotic process remains elusive. …”
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Implementation HR information system – part of a unified information environment of MPEI by I. M. Krepkov, M. R. Ovsyannikova, S. A. Petrov, A. B. Fedorov

“…The result of the work on the HR information system is stably functioning, supporting all business processes of the subject area and have successfully integrated within other software system. …”
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An unraveled mystery: What's the role of brain sphingolipids in neurodegenerative and psychiatric disorders by Xintian Bie, Maoxing Zhang, Qingyu Wang, Ying Wang

“…In recent years, with the development of lipidomics, the role of brain sphingolipids in neurological disorders have raised lots of interests due to their function in neuronal signal transduction and survival. …”
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Comparison of visual outcomes in patients with cataracts and high myopia after implantation of a zonal refractive multifocal or diffractive bifocal intraocular lens by Xinyue Yang, Zhuoya Li, He Zou, Fuqiang Li, Hui Zhang

“…A retrospective analysis was conducted to measure visual acuity at far, intermediate, and near distances, defocus curves, wavefront aberrations, modulation transfer function (MTF), a Quality of Vision questionnaire (QoV) and visual quality self-evaluation were examined at 3 months. …”
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A Twist in Yeast: New Perspectives for Studying TDP-43 Proteinopathies in <i>S. cerevisiae</i> by Roberto Stella, Alessandro Bertoli, Raffaele Lopreiato, Caterina Peggion

“…Additionally, we will explore how modulating proteins involved in these processes reduce TDP-43 toxicity, aiding in restoring normal TDP-43 function or preventing its pathological aggregation. …”
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Four challenging cases of eosinophilic endocarditis or myocarditis with literature review by Ping Chen, Huiling Cheng, Yun Mou

“…After the application of steroid treatment, eosinophil levels decreased rapidly, myocardial thickening was relieved, and cardiac function was gradually recovered. Conclusion This case series embodies the high heterogeneity in the clinical manifestation of the eosinophilic myocarditis or endocarditis, and the important role of multi-module imaging. …”
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PF4 in rejuvenation therapy: neuroprotection and cognitive enhancement by Li Li, Chunming Xie

“…Systemic administration of exogenous PF4 has been shown to reduce circulating pro-aging immune factors and restore peripheral immune function in the aged brain by mitigating age-related hippocampal neuroinflammation, promoting molecular changes in synaptic plasticity, and improving cognitive function in aged mice. …”
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EFM-ResNet: A Feature Enhanced Network for Tobacco Strips Classification by Bo Zhang, Shanshan Zheng, Leyuan Han, Yucan Qiu

“…Finally, a WFL loss function is used to address the limitations of the traditional cross-entropy loss function. …”
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Low-Dose Ribavirin Treatments Attenuate Neuroinflammatory Activation of BV-2 Cells by Interfering with Inducible Nitric Oxide Synthase by Iva Bozic, Danijela Savic, Marija Jovanovic, Ivana Bjelobaba, Danijela Laketa, Nadezda Nedeljkovic, Mirjana Stojiljkovic, Sanja Pekovic, Irena Lavrnja

“…Here, we examined potential of low-dose ribavirin (0.1 and 1 μM) to modulate activated BV-2 microglia. Morphological and functional activation of BV-2 cells was achieved with lipopolysaccharide (LPS) stimulation. …”
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Six-Pack Balancing Act: A Conceptual Model for the Intestinal Lining by PK Rangachari

“…The membranes surrounding these cells show functional differences at the luminal and contraluminal surfaces. …”
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The role of IL-33/ST2 axis in esophageal inflammatory diseases and cancers: implications for the immunopathogenesis and immunotherapeutic target? by Gaofeng Lu, Guanglin Cui

“…Considerable scientific evidence confirms that interleukin (IL)-33 and its main receptor, suppression of tumorigenicity 2 (ST2), form a functional axis to modulate the development of esophageal inflammatory disorders, such as eosinophilic esophagitis and gastroesophageal reflux disease. …”
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