-
6521
-
6522
Exploring immunological alterations of B cells in peripheral immunity via single-cell RNA sequencing: insights into primary membranous nephropathy
Published 2025-08-01“…Additionally, serum galectin-9 levels increased in PMN patients and showed a correlation with proteinuria and renal function in PMN.ConclusionsWe reveal novel insights into the heterogeneity and functional diversity of B cells in patients with PMN. …”
Get full text
Article -
6523
Unraveling the influence of astrocytes on endothelial cell transcription: Towards understanding blood-brain barrier in vitro models’ dynamics
Published 2025-05-01“…Furthermore, astrocytes significantly enhanced transendothelial electrical resistance (TEER) and reduced permeability to tracer Cascade Blue dye, confirming their functional impact on BBB models.By providing a comprehensive human primary cell dataset, this research underscores the pivotal role astrocytes play in shaping endothelial cell gene expression and function in contact coculture systems. …”
Get full text
Article -
6524
Controlled Coffee Intake Enhances Erythrocyte Deformability, Na,K-ATPase Activity, and GSH/GSSG Ratio in Healthy Young Adults
Published 2024-11-01“…Conclusions: The results of this study suggest that controlled coffee intake in healthy young adults can positively influence various indices of erythrocyte functional status. Although the observed statistically significant changes were modest, the findings consistently indicate a positive modulation of erythrocyte properties—cell deformability, oxidative resilience, and active membrane transport of cations—following coffee consumption.…”
Get full text
Article -
6525
-
6526
dFLASH; dual FLuorescent transcription factor activity sensor for histone integrated live-cell reporting and high-content screening
Published 2025-04-01“…We validate dFLASH for functional genomics and drug screening, demonstrating HIF regulation via CRISPRoff and application to whole-genome CRISPR KO screening. …”
Get full text
Article -
6527
Nebivolol effects on myocardial remodelling, inflammation markers and endothelial dysfunction in chronic heart failure patients with or without Type 2 diabetes mellitus
Published 2011-02-01“…The study included 65 patients with functional class (FC) I-III CHF (NYHA classification) of ischemic origin and LV ejection fraction (EF) <50%. …”
Get full text
Article -
6528
The multifaceted role of m5C RNA methylation in digestive system tumorigenesis
Published 2025-03-01“…This review summarizes recent advances in m5C RNA methylation research within digestive system tumors, focusing on its functional mechanisms, clinical significance, and potential applications. …”
Get full text
Article -
6529
Disclosing the benefits of multi-strain compounds and their health impact mechanisms utilizing intestinal biomimetic technology
Published 2025-05-01“…The gut microbiota plays a vital function in preserving intestinal homeostasis and general health. …”
Get full text
Article -
6530
Throughput and delay analysis for IEEE 802.11 multi-hop networks considering data rate
Published 2020-09-01“…In an IEEE 802.11 Distributed Coordination Function–based wireless network with multiple hops, a node operates on its own with several predefined data rates (i.e. following modulation and coding schemes). …”
Get full text
Article -
6531
A Lightweight Model Enhancing Facial Expression Recognition with Spatial Bias and Cosine-Harmony Loss
Published 2024-10-01“…Additionally, a new loss function called Cosine-Harmony Loss is designed. This function optimizes the relative positions of feature vectors in high-dimensional space, resulting in better feature separation and clustering. …”
Get full text
Article -
6532
Dance Movement Recognition Based on Feature Expression and Attribute Mining
Published 2021-01-01“…The test and analysis results on the data set show that the algorithm can recognize the dance movement and improve the accuracy of the dance movement recognition effectively, thus realizing the movement correction function of the dancer.…”
Get full text
Article -
6533
A Hybrid Algorithm Based Static Model Updating Method and Its Application to Spacecraft
Published 2022-01-01“…The re-entry module is taken as the case study, whose thermal deformation is used to construct the objective function for optimization, and precise results are achieved. …”
Get full text
Article -
6534
Long noncoding RNA MARL regulates antiviral responses through suppression miR-122-dependent MAVS downregulation in lower vertebrates.
Published 2020-07-01“…However, the function roles of lncRNAs in lower vertebrates are still unknown. …”
Get full text
Article -
6535
DSIF factor Spt5 coordinates transcription, maturation and exoribonucleolysis of RNA polymerase II transcripts
Published 2025-01-01“…Abstract Precursor messenger RNA (pre-mRNA) is processed into its functional form during RNA polymerase II (Pol II) transcription. …”
Get full text
Article -
6536
TERT PfeRNA regulates telomere length during cellular senescence of normal human bronchial epithelial cells
Published 2025-07-01“…Although telomerase reverse transcriptase (TERT) is central to telomere maintenance, the discrepancy between TERT level and telomere length highlights the unidentified molecules that regulate TERT’s functional activities. Here, we identify novel TERT-associated protein functional effector sncRNAs (TpfeRNAs) that modulate telomerase activity and telomere length during cellular senescence of normal human bronchial epithelial (NHBE) cells. …”
Get full text
Article -
6537
The underlying molecular mechanisms and biomarkers of Hip fracture combined with deep vein thrombosis based on self sequencing bioinformatics analysis
Published 2025-05-01“…Functional enrichment analysis was then performed to explore the roles of the candidate genes. …”
Get full text
Article -
6538
Can repetitive transcranial magnetic stimulation promote recovery of consciousness in patients with disorders of consciousness? A randomized controlled trial
Published 2025-01-01“…It might get involved in modulating the balance among cerebral functional networks and facilitating consciousness recovery.…”
Get full text
Article -
6539
-
6540
Development of KASP markers for FT family genes in soybean
Published 2025-06-01“…In this study, we identified 10 FT family genes in soybean and examined their functional divergences through sequence alignment analysis. …”
Get full text
Article