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6441
Advances in enhancing hydrodeoxygenation selectivity of lignin-derived oxygenates: From synthetic strategies to fundamental techniques
Published 2025-02-01“…However, LDOs, existing as complex aromatic mixtures with diverse oxygen-containing functional groups, pose a challenge as they cannot be easily separated via distillation for direct utilization. …”
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6442
Peptide Drug: Design and Clinical Applications
Published 2025-08-01“…They exert critical roles in disease‐associated metabolic reprogramming and immune modulation by activating cell signaling pathways, regulating metabolic processes, and immune cell functions. …”
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6443
Single‐Cell Analysis of Alternative Splicing and Gene Regulatory Network Reveals Remarkable Expression and Regulation Dynamics During Human Early Embryonic Development
Published 2025-07-01“…Additionally, we identified functionally important specific gene regulatory modules for each stage and revealed dynamic usage of transcription factor binding motifs (TFBMs). …”
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6444
Dynamic gene regulatory networks drive seed dormancy and germination of Pinus tabuliformis
Published 2025-08-01“…Notably, PtbZIP25 (Pt4G12300) a homolog of Arabidopsis thaliana bZIP transcription factors, was functionally validated as a negative regulator of germination via overexpression and mutant assays. …”
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6445
Impact of temperature humidity index-based climate services for Murrah buffaloes of India on operational decision-making and economic outcome of the farm
Published 2024-12-01“…Climate change is likely to affect both the productive and reproductive functions of Murrah buffaloes, the major milch breed of India. …”
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6446
SECURITY ASSESSMENT OF MOODLE-BASED DISTANCE LEARNING SYSTEM COMPONENTS USING STATIC ANALYSIS TOOLS
Published 2025-07-01“…Moodle is one of the most popular open source solutions used in university environments, and its modular architecture requires regular security audits due to continuous functional expansion. Within the scope of the study, a critically important module — moodle-tool_componentlibrary – was selected for analysis. …”
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6447
FMRI reveals a dissociation between grasping and perceiving the size of real 3D objects.
Published 2007-05-01“…<h4>Background</h4>Almost 15 years after its formulation, evidence for the neuro-functional dissociation between a dorsal action stream and a ventral perception stream in the human cerebral cortex is still based largely on neuropsychological case studies. …”
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6448
Xylose-Oligosaccharide Alleviating Type 2 Diabetes in Mice via Reducing Blood Glucose, Oxidative Stress, Inflammation and Regulating Intestinal Microbiota
Published 2025-06-01“…These results suggested that xylose-oligosaccharide had hypoglycemic effects, reduced insulin resistance and oxidative stress, possessed anti-inflammatory properties, and modulated intestinal microbiota. Thus, xylose-oligosaccharide shows promise as a functional food for managing type 2 diabetes.…”
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6449
Design and implementation of J2EE-based statement feature recognition in English teaching system optimization
Published 2024-12-01“…This paper analyzes and explains the overall structure of the J2Ee-based English teaching system, briefly introduces the overall framework of the whole website, and introduces the main functions of each functional module of the website. …”
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6450
A cryptic promoter in the exon of HKR1 drives expression of a truncated form of Hkr1 in Saccharomyces cerevisiae.
Published 2024-01-01“…This shorter protein still conferred resistance to the HM-1 killer toxin, suggesting that this cryptic promoter helps carry out Hkr1-mediated signal transduction efficiently by producing a specific Hkr1 domain with functions as a signaling messenger. Notably, reporter assays using the fluorescent protein gene mUkG1 and the β-galactosidase gene lacZ revealed that the transcriptional activity of this cryptic promoter was modulated by its upstream sequence within the single exon. …”
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6451
The regulative role and mechanism of BNST in anxiety disorder
Published 2024-12-01“…Innovative multimodal imaging techniques, such as functional magnetic resonance imaging (fMRI) and positron emission tomography (PET), have non-invasively illuminated BNST activities and their functional connections with other brain areas. …”
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6452
Software and Hardware Control System for Implementing the Balance Error Scoring System
Published 2025-05-01“…For real-time data transmission to the PC screen and smartphone, wireless modules HC-05 (Bluetooth) or ESP32 (Wi-Fi) were used. …”
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6453
Expression characteristics, molecular mechanisms, and clinical significance of DICER1 in breast cancer
Published 2025-07-01“…Weighted gene co-expression network analysis (WGCNA) was used to identify gene modules associated with the breast cancer phenotype, and gene set enrichment analysis (GSEA) was performed to explore their biological functions. …”
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6454
A Novel Molecular Classification Method for Glioblastoma Based on Tumor Cell Differentiation Trajectories
Published 2023-01-01“…Each cluster exhibited different potential drug sensitivities, pathways, functions, and transcriptional modules. The classification model was further examined in TCGA and CGGA datasets. …”
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6455
The chromosome-level genome of Hemerocallis middendorffii provides new insights into the floral scents and color biosynthesis in Chinese native daylily
Published 2025-07-01“…Conclusions This study not only provides new insights into the molecular mechanisms of floral scent and color, but also lays a foundation for subsequent research on key gene functions and molecular breeding in Hemerocallis.…”
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6456
TREE: Bridging the gap between reconfigurable computing and secure execution
Published 2025-06-01“…Additionally, TREE provides essential TEE services within the FPGA fabric, including secure storage and cryptographic functions, enabling TAs to securely store sensitive data and perform critical operations in an isolated environment. …”
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6457
Spatial-Spectral Linear Extrapolation for Cross-Scene Hyperspectral Image Classification
Published 2025-05-01“…However, recent studies have shown that the activation functions of neurons in a network exhibit asymmetry for different categories, which results in the learning of task-irrelevant features while attempting to learn task-related features (called “feature contamination”). …”
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6458
BePresent Universal Internet-Based Parenting Intervention: Single-Arm Pre-Post Intervention Study
Published 2025-03-01“…Parents reported improvement in the daily functioning of their child when it was measured with a questionnaire adapted from the Barkley Home Situations Questionnaire (P=.01; d=0.14). …”
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6459
GIRH-Unet: Improved Residual Tobacco Segmentation Algorithm Based on GhostNetV3-Unet
Published 2025-01-01“…Additionally, we optimize the residual modules and activation functions to enhance the extraction of detailed features and the deep transmission of information. …”
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6460
TriM-Net: Trinityformer-Mamba fusion for road extraction in remote sensing
Published 2025-09-01“…The feedforward network employs a Kolmogorov-Arnold network (KAN), reducing neuron count while enhancing local detail capture using edge activation functions and the Arnold transform. Additionally, the normalization layer integrates the benefits of BatchNorm and LayerNorm for better performance. …”
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