The protocol for a pilot feasibility trial of Improving Neurodevelopmental ouTcomes After prenatal Cannabinoid in uTero exposure (INTACT) study for a multi-center trial. by Jessie R Maxwell, Leigh-Anne Cioffredi, Maria M Talavera-Barber, Matthew Henry, Sandra Beauman, Anne Hittson, Meggie McCoy, Laurie Chassereau, Jing Jin, Preetha A Abraham, Linda Y Fu, Hengameh Raissy, Jessica N Snowden

“…In other high-risk populations, interventions aimed at increasing parental responsiveness have improved cognitive functioning in the children. This pilot trial aims to utilize a contingent responding training program in birthing parent-infant dyads with prenatal cannabinoid exposure to assess the feasibility of recruitment, completion of the proposed intervention and adherence.…”
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XCF-LSTMSATNet: A Classification Approach for EEG Signals Evoked by Dynamic Random Dot Stereograms by Tingting Zhang, Xu Yan, Xin Chen, Yi Mao

“…This capability is deeply intertwined with cognitive brain functions. To explore the impact of stereograms with varied motions on brain activities, we collected Electroencephalography (EEG) signals evoked by Dynamic Random Dot Stereograms (DRDS). …”
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Mechanical and finite element models of corneal keratoprostheses by A. N. Soloviev, N. I. Glushko, A. N. Epikhin, M. Swain, О. N. Lesnyak, А. Е. Ivanov

“…Two types of keratoprostheses are considered: the first type with a support plate and the second type with an intermediate functionally gradient layer. The stress-strain state of the prosthesis is calculated for the first type. …”
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m6A-related genes of peripheral white blood cell in spinal cord injury as potential targets for prognosis and treatment by Mingran Luo, Qian Wang, Jian Chen, Guoyong Yin

“…Further understanding of the functions of the identified SCI hub genes may provide deeper insights into the molecular mechanisms of SCI.…”
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Unraveling the role of neuregulin-mediated astrocytes-OPCs axis in the pathogenesis of age-related macular degeneration and Parkinson’s disease by Shuyan Zhang, Cheng Zhang, Yinjian Zhang, Yibin Feng

“…Cell-cell chat was utilized to predict intercellular communication and signaling pathways. Module eigengenes (MEs) were calculated to identify specific gene modules. …”
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Automation facilities for agricultural machinery control by A. Yu. Izmaylov, V. K. Khoroshenkov, V. A. Kolesnikova, I. S. Alekseev, S. E. Lonin, N. T. Goncharov

“…Feedback at technological processes control in agricultural production allows to optimally solve a problem of rational distribution of functions in man-distributed systems and forming the intelligent ergonomic interfaces, consistent with professional perceptions of decision-makers. …”
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geodl: An R package for geospatial deep learning semantic segmentation using torch and terra. by Aaron E Maxwell, Sarah Farhadpour, Srinjoy Das, Yalin Yang

“…The geodl package provides utility functions for creating raster masks or labels from vector-based geospatial data and image chips and associated masks from larger files and extents. …”
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User activity monitoring and automated office IT infrastructure management system by V.V. Vorotnikov, O.O. Shelukha, K.I. Matvieiev

“…The platform is designed to incorporate self-learning mechanisms, contextual awareness, and multi-agent coordination–supporting the transition from conventional monitoring tools to an adaptive, intelligent infrastructure aligned with Industry 4.0 paradigms, where each workstation functions as a smart sensor-actuator unit in the organizational IT landscape.…”
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Variation-Difference Method of Calculation of Layered Rubber-Metal Vibration Isolators Used for Protection of Reinforced Concrete Buildings from Anthropogenic Vibration by D. K. Sizov

“…Only some of the software packages implementing the FEM solve optimization problems of the shape of the product being calculated, most often it is related to foreign software products with universal functionality. Variation-difference method (VDM) is the closest to the finite element method (FEM) in terms of its computational capabilities. …”
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IoT-Based Smart Utility Control System by Khansa niazi, Waleed Ahmad, Muhammad Hassan Nadeem

“…These systems require specialized and costly appliances for their functionality, making them less accessible to average users, especially in regions with limited resources [1].  …”
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Artificial Intelligence Systems for Solving Problems of Agro­Industrial Complex Digitalization and Robotization by A. L. Ronzhin, A. I. Savel'ev

“…The authors carried out wireless registration of measured and calculated parameters received from the distributed sensors, conducted their analysis based on big data technologies and proactive control of cyber-physical devices responsible for the functioning of the aqua and phytocultures life support systems. …”
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Regulatory T cells in neurological disorders and tissue regeneration: Mechanisms of action and therapeutic potentials by Jing Jie, Xiaomin Yao, Hui Deng, Yuxiang Zhou, Xingyu Jiang, Xiu Dai, Yumin Yang, Pengxiang Yang

“…By leveraging the pivotal and diverse functions of Tregs in immune modulation and tissue repair, regulatory T cells–based therapies may lead to transformative breakthroughs in the treatment of neurological diseases.…”
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New Perspectives on Postmenopausal Osteoporosis: Mechanisms and Potential Therapeutic Strategies of Sirtuins and Oxidative Stress by Huiying Zhao, Fan Yu, Wei Wu

“…SIRTs are enzymes that function as NAD+-dependent deacetylases. SIRTs can modulate osteocyte function, sustain mitochondrial homeostasis, and modulate relevant signaling pathways, thereby improving bone metabolic imbalances, reducing bone resorption, and promoting bone formation. …”
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The whole genome analysis of the wild-type and attenuated orf virus reveals that ORF022 facilitates viral replication by Tian Jing, Yunpeng Wang, Yukun Bu, Xi Chen, Shutong Feng, Wenbo Liu, Zhannur Niyazbekova, Dekun Chen, Xiaolong Gao, Wentao Ma

“…Additionally, we noticed that 24 genes in the attenuated strain had SNPs, with the highest number of mutations occurring in the ORF022 gene. The function of the ORF022 gene has not been previously reported. …”
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Whole-Exome Sequencing Identified Molecular Variants Linked to the Progression of Gastric Precancerous Lesions in Patients from Southwestern Colombia—An Exploratory Approach by Lizeth Mejia-Ortiz, Jovanny Zabaleta, Jone Garai, Luis Eduardo Bravo, Andres Castillo

“…Associations between molecular variants and lesion progression were analyzed using Fisher’s exact test and the Cochran–Armitage trend test. Additionally, functional impact and pathway enrichment analyses were performed for variants that showed significant associations. …”
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Predictors of pain reduction following manual therapy in patients with temporomandibular disorders: a protocol for a prospective observational study by Alison B Rushton, Nicola R Heneghan, Deborah Falla, Giacomo Asquini, Andrea Edoardo Bianchi, Giulia Borromeo, Matteo Locatelli

“…Manual therapy, like other recommended conservative treatments included in clinical guidelines, is commonly used to treat patients with TMD to reduce pain and improve function. However, outcomes may be variable. The aim of this study is to identify predictors associated with pain reduction in patients with TMD following manual therapy by analysing a combination of patient-reported outcome measures and clinical tests. …”
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Hsa_circ_0001859 promotes NSCLC progression through the miRNA-101-3p/MMP1 axis by Jianxin Tan, Zhenyu Fan, Rongguo Lu, Shugao Ye

“…Bioinformatics analysis and rescue experiments disclosed that circ_0001859 functioned as a sponge for miR-101-3p, modulating MMP1 expression and thereby controlling NSCLC development and metastasis. …”
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Hsa-miR-21 promoted the progression of lung adenocarcinoma by regulating LRIG1 expression by Li Liu, Xinhua Liu, Chengpeng Gao, Meijuan Liu, Mengmeng Peng, Leqiang Wang

“…The differential expression analysis and gene set enrichment analysis (GSEA) were performed using “limma” and “clusterProfiler” function package, respectively. The levels of hsa-miR-21 mRNA and LRIG1 mRNA and LRIG1 protein expressions were analyzed using RT-qPCR and western blot analysis. …”
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Hydrolyzable Bio‐Based Bisphenols Enabled by the Tishchenko Reaction for Polyurethane Vitrimers with Closed‐Loop Recyclability by Jiewen Wang, Hongru Qiang, Rong Huang, Dan Zhao, Zihan Tong, Zhen Fan, Jianzhong Du, Yunqing Zhu

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Current Review of Heart Failure-Related Risk and Prognostic Factors by Michał Maksymilian Wilk, Jakub Wilk, Szymon Urban, Piotr Gajewski

“…These findings underscore the importance of miRNAs in modulating the structural and functional changes seen in HF. …”
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