Subthalamic nucleus deep brain stimulation for cranial-cervical dystonia: optimal stimulation sites and networks by Hutao Xie, Jiansong Huang, Ningfei Li, Houyou Fan, Shihang Yang, Zixiao Yin, Zhaoting Zheng, Zehua Zhao, Yin Jiang, Lin Shi, Anchao Yang, Fangang Meng, Guanyu Zhu, Quan Zhang, Jianguo Zhang

“…Functional network mapping further revealed connectivity to the sensorimotor cortex as significantly associated with clinical improvement (R = 0.43, p = 0.002). …”
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Achieving High‐Performance Organic Long Persistent Luminescence Materials via Manipulation of Radical Cation Stability by Hongxin Gao, Guangming Wang, Tengyue Wang, Zi Ye, Qianqian Yan, Qianhui Chong, Chin‐Yiu Chan, Biaobing Wang, Kaka Zhang

“…Furthermore, these OLPL materials exhibit time‐encoded afterglow properties and promising applications in advanced anti‐counterfeiting, as well as background‐independent bioimaging functions. This work not only provides a novel strategy for constructing high‐performance OLPL materials but also lays a foundation for their widespread application in various fields.…”
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Effect of propofol and ciprofol in patients undergoing bronchoscopy: protocol for a double-blind, randomised controlled trial by Fang Chen, Cheng Li, Dongliang Li, Jinxuan Tang, Jiayu Huang

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The Impact of Zinc Supplementation on the Course of Infections by Justyna Woźniak, Ewelina Kopczyńska, Piotr Kulej, Wiktor Biesiada, Justyna Weronika Kmieć, Anna-Mariia Chernysh, Aleksandra Dusińska, Jakub Waszczyński, Kamila Fuczyło, Karolina Stankevič

“…Introduction Zinc plays a vital role in immune function, enhancing defense mechanisms and reducing infection duration and severity. …”
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The role of microglia in multiple sclerosis: implications for treatment with Bruton’s tyrosine kinase inhibitors by Patrick Vermersch, Laura Airas, Laura Airas, Thomas Berger, Thomas Berger, Florian Deisenhammer, Nikolaos Grigoriadis, Hans-Peter Hartung, Hans-Peter Hartung, Hans-Peter Hartung, Melinda Magyari, Melinda Magyari, Veronica Popescu, Veronica Popescu, Veronica Popescu, Carlo Pozzilli, Maura Pugliatti, Maura Pugliatti, Bart Van Wijmeersch, Bart Van Wijmeersch, Bart Van Wijmeersch, Magd Zakaria, Celia Oreja-Guevara, Celia Oreja-Guevara

“…BTK inhibitors and other novel treatments for MS, including masitinib and frexalimab, show promise in modulating microglial function and influencing the disease progression rate.ConclusionsThe multifaceted roles of microglia in CNS development, immune surveillance, and particularly in the pathogenesis of MS highlight the potential of targeting microglial functions in MS treatment. …”
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Analysis of the Changes in Physicochemical Properties and Microbial Communities During Fermentation of Sweet Fermented Rice by Jiaqiong Wan, Ping Tian, Xiaozhen Liu, Hanyao Zhang

“…Moreover, the three primary functions of glycosyltransferases (GTs), glycoside hydrolases (GHs), and carbohydrate-binding modules (CBMs) in carbohydrate enzyme analysis were involved in the whole fermentation process. …”
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Obesity and cervical intraepithelial neoplasia: regulation of mitochondrial energy metabolism via the Kisspeptin/GPR54 signaling pathway by Jiajia Pan, Yuanyuan Chen, Yan Ye, Peipei Li, Feifei Ni, Haizhen He

“…Transcriptomic analysis identified KISS1R as a key gene. Functional assays in cervical cancer (CC) cell lines, including CCK-8, wound healing, and Transwell assays, were used to evaluate the effects of KISS1 modulation. …”
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Dynamic causal modeling of neural responses to an orofacial pneumotactile velocity array by Yingying Wang, Rebecca Custead, Hyuntaek Oh, Steven M. Barlow

“…Moreover, the velocity pneumotactile stimuli influenced the contralateral M1 through contralateral SI and SII, indicating that passive pneumotactile stimulation may positively impact motor function rehabilitation. Furthermore, the medium velocity 25 cm/s pneumotactile stimuli modulated both forward and backward connections between the right cerebellar lobule VI and the contralateral left SI and M1. …”
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Geometric Detail-Preserved Point Cloud Upsampling via a Feature Enhanced Self-Supervised Network by Shengwei Qin, Yao Jin, Hailong Hu

“…The first module, called the feature enhancement module (FEM), aims to prevent feature blurring. …”
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Rapid plasticity of visually evoked responses in rat monocular visual cortex. by Trevor C Griffen, Melissa S Haley, Alfredo Fontanini, Arianna Maffei

“…In V1m there is currently no evidence for functional changes occurring within a time window compatible with that of local circuit plasticity. …”
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Metabolism: a potential regulator of neutrophil fate by Zhou Yipeng, Cao Chao, Li Ranran, Pan Tingting, Qu Hongping

“…Neutrophils are essential components of the innate immune system that defend against the invading pathogens, such as bacteria, viruses, and fungi, as well as having regulatory roles in various conditions, including tissue repair, cancer immunity, and inflammation modulation. The function of neutrophils is strongly related to their mode of cell death, as different types of cell death involve various cellular and molecular alterations. …”
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Trimetallic@Cyclodextrin Nanocomposite: Photocatalyst for Degradation of Amoxicillin and Catalyst for Esterification Reactions by Gaurav Sharma, Alberto García-Peñas, Mu. Naushad, Amit Kumar, Mika Sillanpää, Forian J. Stadler

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Raman spectroscopy and bioinformatics-based identification of key genes and pathways capable of distinguishing between diffuse large B cell lymphoma and chronic lymphocytic leukemi... by Haoyue Liang, Haoyue Liang, Zhijie Cao, Zhijie Cao, Yansong Ren, Yansong Ren, Yihan Li, Yihan Li, Haoyu Wang, Haoyu Wang, Fanfan Sun, Fanfan Sun, Mei Xue, Guoqing Zhu, Guoqing Zhu, Yuan Zhou, Yuan Zhou

“…This strategy revealed many up- and down-regulated DEGs, with functional enrichment analyses identifying these genes as being closely associated with inflammatory and immune response activity. …”
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Mechanism of action behind the pain-relief effects of extracellular vesicles in microfragmented adipose tissue: an in vitro and in vivo study by Francesco De Francesco, Letizia Ferroni, Ilaria Zanolla, Lucia Sileo, Maria Pia Cavaleri, Mario Fordellone, Letizia Senesi, Anna Maria Monachino, Elena Tremoli, Ilenia Pia Cappucci, Eduardo Maria Sommella, Massimo Bonora, Alfredo Ronca, Ugo D’Amora, Noemi De Cesare, Luca Lovatti, Michele Riccio, Ali Mobasheri, Paolo Pinton, Barbara Zavan

“…Results Functional studies demonstrated that EVs modulate calcium signaling and mitochondrial activity, enhancing cellular bioenergetics and mitigating inflammation-induced dysfunction. …”
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Restoration of antibiotic associated diarrhea induced gut microbiota disorder by using Dictyophora indusiata water-insoluble polysaccharides in C57BL/6J mice by Yong Lai, Yong Lai, Qifan Zhang, Maohan Xu, Xiurong Guo, Quan Zhou, Qiuyu Liu, Huiling Deng, Can Song

“…Also, compared with the NR group, DIPY increasing the relative abundance of Parasutterella and Blautia, increasing the production of acetic acid (p < 0.001), and decreasing the levels of LPS, MCP-1, TNF-α, and IL-6 (p < 0.05) which attenuating inflammatory responses.ConclusionThis study demonstrated that DIPY has intestinal prebiotic function, which provides a basis for further development of functional products for the treatment of AAD.…”
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Lysosomal targeting of liposomes with acidic pH and Cathepsin B induces protein aggregate clearance by Minsol Jeon, Da-Eun Kim, So Young Choi, Seoyoung Kim, Seongchan Kim, Hyojin Lee, Hyunkyung Kim

“…In this study, liposome-based lysosomal pH-modulating particles (LPPs), containing a liquid solution to adjust lysosomal pH, have been developed to restore lysosomal function. …”
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Double-blind, randomized, placebo-controlled pilot clinical trial with gamma-band transcranial alternating current stimulation for the treatment of schizophrenia refractory auditor... by Xiaojuan Wang, Xiaochen Zhang, Yuan Chang, Jingmeng Liao, Shuang Liu, Dong Ming

“…Transcranial alternating current stimulation is thought to enhance connectivity between different brain regions by modulating brain oscillations. In this work, we applied a frontal-temporal-parietal 40 Hz-tACS stimulation strategy for treating auditory hallucinations and further explored the effect of tACS on functional connectivity of brain networks. 32 schizophrenia patients with refractory auditory hallucinations received 20daily 20-min, 40 Hz, 1 mA sessions of active or sham tACS on weekdays for 4 consecutive weeks, followed by a 2-week follow-up period without stimulation. …”
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Effects of in Vitro Fermentation of Citrus medica var. sarcodactylis Polysaccharides on Hypoglycemic Activity, Gut Microbiota and Structural Alterations by Cheng ZHONG, Junyun LUO, Wencong MA, Aimei ZHOU

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Polarization of macrophages: mechanisms, markers and factors of induction by A. A. Fedorov, N. A. Ermak, T. S. Gerashchenko, E. B. Topolnitskii, N. A. Shefer, E. O. Rodionov, M. N. Stakheyeva

“…The  variability  of  the  macrophage’s participation in tumor progression, determined by their functional polarization, opens up a wide prospect for modulating their functional profile, primarily in the direction of increasing antitumor activity. …”
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The Role of Genistein in Type 2 Diabetes and Beyond: Mechanisms and Therapeutic Potential by Mateusz Kciuk, Weronika Kruczkowska, Katarzyna Wanke, Julia Gałęziewska, Damian Kołat, Somdutt Mujwar, Renata Kontek

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